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Intra-vaginal prostaglandin E2 versus double-balloon catheter for labor induction in term oligohydramnios

Abstract

Objective:

Compare mechanical and pharmacological ripening for patients with oligohydramnios at term.

Study design:

Fifty-two patients with oligohydramnios 5 cm and Bishop score 6 were randomized for labor induction with a vaginal insert containing 10 mg timed-release dinoprostone (PGE2) or double-balloon catheter. The primary outcome was time from induction to active labor. Time to labor, neonatal outcomes and maternal satisfaction were also compared.

Result:

Baseline characteristics were similar. Time from induction to active labor (13 with PGE2 vs 19.5 h with double-balloon catheter; P=0.243) was comparable, with no differences in cesarean rates (15.4 vs 7.7%; P=0.668) or neonatal outcomes. The PGE2 group had higher incidence of early device removal (76.9 vs 26.9%; P=0.0001), mostly because of active labor or non-reassuring fetal heart rate. Fewer PGE2 patients required oxytocin augmentation for labor induction (53.8 vs 84.6% P=0.034). Time to delivery was significantly shorter with PGE2 (16 vs 20.5 h; P=0. 045)

Conclusion:

Intravaginal PGE2 and double-balloon catheter are comparable methods for cervical ripening in term pregnancies with oligohydramnios.

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Acknowledgements

This study was not supported by external funding. Faye Schreiber is thanked for help in preparing this manuscript.

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Correspondence to G Shechter-Maor.

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Shechter-Maor, G., Haran, G., Sadeh-Mestechkin, D. et al. Intra-vaginal prostaglandin E2 versus double-balloon catheter for labor induction in term oligohydramnios. J Perinatol 35, 95–98 (2015). https://doi.org/10.1038/jp.2014.173

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  • DOI: https://doi.org/10.1038/jp.2014.173

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