Original Article

Journal of Perinatology (2009) 29, 606–611; doi:10.1038/jp.2009.57; published online 21 May 2009

Patient selection for neonatal extracorporeal membrane oxygenation: beyond severity of illness
JPEROpen

R L Chapman1,4, S M Peterec1,3,4, M J Bizzarro1 and M R Mercurio1,2

  1. 1Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
  2. 2Yale Pediatric Ethics Program, Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
  3. 3Department of Pediatrics, Lawrence & Memorial Hospital, New London, CT, USA

Correspondence: Dr SM Peterec, Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, PO Box 208064, New Haven, CT 06520-5426, USA. E-mail: steven.peterec@yale.edu

4These authors contributed equally to this work.

Received 21 November 2008; Revised 9 March 2009; Accepted 29 March 2009; Published online 21 May 2009.

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Abstract

Objective:

 

To explore how neonates with respiratory failure are selected for extracorporeal membrane oxygenation (ECMO) once severity of illness criteria are met, and to determine how conflicts between ECMO providers and parents over the initiation of ECMO are addressed.

Study Design:

 

A cross-sectional study was conducted using a data collection survey, which was sent to the directors of neonatal respiratory ECMO centers.

Result:

 

The lowest birth weight and gestational age at which respondents would consider placing a neonate on ECMO were frequently below recommended thresholds. There was wide variability in respondents' willingness to place neonates on ECMO in the presence of conditions such as intraventricular hemorrhage and hypoxic ischemic encephalopathy. The number of respondents who would never seek to override parental refusal of ECMO was equal to the number who would always do so.

Conclusion:

 

Significant variability exists in the selection criteria for neonatal ECMO and in how conflicts with parents over the provision of ECMO are resolved.

Keywords:

ECMO, newborn, respiratory failure, ethics

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