Perinatal/Neonatal Case Presentation

Journal of Perinatology (2009) 29, 66–68; doi:10.1038/jp.2008.137

Persistent vancomycin and high-level gentamicin-resistant Enterococcus faecium bacteremia and intra-aortic thrombus in an extremely low birth-weight infant

N Hapnes1, A Twomey1 and S Knowles2

  1. 1Department of Neonatology, The National Maternity Hospital, Dublin, Ireland
  2. 2Department of Microbiology, The National Maternity Hospital, Dublin, Ireland

Correspondence: Dr N Hapnes, Apt 12 Temple Place, Grenville Street, Dublin 1, Ireland. E-mail: ninahapnes@hotmail.com

Received 11 February 2008; Revised 28 July 2008; Accepted 31 July 2008.

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Abstract

Vancomycin-resistant Enterococcus (VRE) sepsis is emerging as a significant problem in the intensive care setting. The treatment at any age is challenging, but there is a dearth of information on this infection and its treatment in the very premature infant. We describe successful treatment of persistent bacteremia caused by Enterococcus faecium with vancomycin and high-level gentamicin resistance in a 10-day-old former 23-week premature male infant.

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