Perinatal/Neonatal Case Presentation

Journal of Perinatology (2007) 27, 388–389; doi:10.1038/sj.jp.7211732

Premature twins of a mother with Graves' disease with discordant thyroid function: a case report

M J O'Connor1, A O Paget-Brown2 and W L Clarke3

  1. 1Division of General Pediatrics, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA, USA
  2. 2Division of Neonatology, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA, USA
  3. 3Division of Endocrinology, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA, USA

Correspondence: Dr WL Clarke, Division of Endocrinology, Department of Pediatrics, University of Virginia Health System, PO Box 800386, Charlottesville, VA 22908-0386, USA. E-mail: wlc@virginia.edu

Received 18 September 2006; Revised 3 February 2007; Accepted 9 February 2007.

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Abstract

Thyroid dysfunction is recognized in the newborns of mothers affected by Graves' disease during pregnancy. We describe the development of concurrent hyperthyroidism and hypothyroidism in the twin infants of a mother with Graves' disease diagnosed during pregnancy.

Keywords:

hypothyroidism, neonate, Graves' disease, pregnancy, hyperthyroidism

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