TABLE 2
FROM:
Latest Insights into Skin Hyperpigmentation
Jean-Paul Ortonne and Donald L Bissett
BACK TO ARTICLETable 2. Pigmentation control targets and effective agents
| Pigmentation control target | Effective agent |
|---|---|
| Tyrosinase inhibition | Hydroquinone, resorcinols, kojic acid, arbutin, ascorbic acid (vitamin C), deoxyarbutin |
| Tyrosinase copper chelation | Ellagic acid |
| Inhibition of tyrosinase glycosylation | Glucosamine, N-acetyl glucosamine, tunicamycin |
| Melanosome transfer | Niacinamide, protease inhibitors |
| Downregulation of tyrosinase | Retinoid (trans-retinoic acid, retinol and its esters, retinaldehyde) |
| Antioxidant | Vitamin C compounds, vitamin E, sulfhydryl compounds |
| Anti-inflammatory agent | Hydrocortisone, phytosterol, glycyrrhetinic acid |
| Increase epidermal turnover | Retinoids, salicylic acid |
