Journal of Investigative Dermatology

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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November 19 2009

Original Articles

Functional MC1R-Gene Variants Are Associated with Increased Risk for Severe Photoaging of Facial Skin

Anissa Elfakir, Khaled Ezzedine, Julie Latreille, Laurence Ambroisine, Randa Jdid, Pilar Galan, Serge Hercberg, Florian Gruber, Denis Malvy, Erwin Tschachler and Christiane Guinot

J Invest Dermatol advance online publication, November 19, 2009; doi:10.1038/jid.2009.366

Abstract | Full Text | PDF | Supplementary information

Molecular Analysis of Tumor-Promoting CD8⁺ T Cells in Two-Stage Cutaneous Chemical Carcinogenesis

Bernice Y Kwong, Scott J Roberts, Tobias Silberzahn, Renata B Filler, Jason H Neustadter, Anjela Galan, Swapna Reddy, William M Lin, Peter D Ellis, Cordelia F Langford, Adrian C Hayday and Michael Girardi

J Invest Dermatol advance online publication, November 19, 2009; doi:10.1038/jid.2009.362

ADVANCE ONLINE PUBLICATION

November 19 2009

Original Articles

Functional MC1R-Gene Variants Are Associated with Increased Risk for Severe Photoaging of Facial Skin

Molecular Analysis of Tumor-Promoting CD8+ T Cells in Two-Stage Cutaneous Chemical Carcinogenesis

The Suppressor of Cytokine Signaling (SOCS)-3 Determines Keratinocyte Proliferative and Migratory Potential during Skin Repair

Epithelial Overexpression of SOCS-3 in Transgenic Mice Exacerbates Wound Inflammation in the Presence of Elevated TGF-1

Compound Heterozygous Desmoplakin Mutations Result in a Phenotype with a Combination of Myocardial, Skin, Hair, and Enamel Abnormalities

Seroreactivity of 38 Human Papillomavirus Types in Epidermodysplasia Verruciformis Patients, Relatives, and Controls

Keratinocytes Synthesize Enteropeptidase and Multiple Forms of Trypsinogen during Terminal Differentiation

Possible Roles of IL-27 in the Pathogenesis of Psoriasis

Alterations of the Cell-Cycle Inhibitors p27KIP1 and p16INK4a Are Frequent in Blastic Plasmacytoid Dendritic Cell Neoplasms

Letter to the Editor

Epidermal Barrier Dysfunction in Non-Atopic HIV: Evidence for an "Inside-to-Outside" Pathogenesis

November 12 2009

Original Articles

Bmi-1 Reduction Plays a Key Role in Physiological and Premature Aging of Primary Human Keratinocytes

The Histamine H4 Receptor Mediates Inflammation and Pruritus in Th2-Dependent Dermal Inflammation

November 5 2009

Original Articles

Genome-Wide Association Study of Generalized Vitiligo in an Isolated European Founder Population Identifies SMOC2, in Close Proximity to IDDM8

Resistance of Cutaneous Anaplastic Large-Cell Lymphoma Cells to Apoptosis by Death Ligands Is Enhanced by CD30-Mediated Overexpression of c-FLIP

Epidermal Langerhans Cells Rapidly Capture and Present Antigens from C-Type Lectin-Targeting Antibodies Deposited in the Dermis

EGFR Regulates the Expression of Keratinocyte- Derived Granulocyte/Macrophage Colony-Stimulating Factor In Vitro and In Vivo

Genotypic and Clinical Spectrum of Self-Improving Collodion Ichthyosis: ALOX12B, ALOXE3, and TGM1 Mutations in Scandinavian Patients

Letters to the Editor

No Correlation between the Molecular Subtype of COL1A1–PDGFB Fusion Gene and the Clinico-Histopathological Features of Dermatofibrosarcoma Protuberans

Mind the (Gender) Gap: Does Prolactin Exert Gender and/or Site-Specific Effects on the Human Hair Follicle?

October 29 2009

Perspective

Familial Tumoral Calcinosis: From Characterization of a Rare Phenotype to the Pathogenesis of Ectopic Calcification

Original Articles

Pediatric Mastocytosis Is a Clonal Disease Associated with D816V and Other Activating c-KIT Mutations

AGE-Modified Collagens I and III Induce Keratinocyte Terminal Differentiation through AGE Receptor CD36: Epidermal–Dermal Interaction in Acquired Perforating Dermatosis

IL-18 Downregulates Collagen Production in Human Dermal Fibroblasts via the ERK Pathway

ADAM10 Is Upregulated in Melanoma Metastasis Compared with Primary Melanoma

A Comprehensive Analysis Reveals Mutational Spectra and Common Alleles in Chinese Patients with Oculocutaneous Albinism

Letter to the Editor

Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia

October 22 2009

Perspective

KIT as a Therapeutic Target in Melanoma

Original Article

ERK Involvement in Resistance to Apoptosis in Keratinocytes with Mutant Keratin

Letter to the Editor

Pemphigus Vulgaris in White Europeans Is Linked with HLA Class II Allele HLA DRB1*1454 but Not DRB1*1401

October 15 2009

Perspective

Vaccines and Microbicides Preventing HIV-1, HSV-2, and HPV Mucosal Transmission

Original Articles

Melanoma Thickness Trends in the United States, 1988–2006

Agents that Reverse UV-Induced Immune Suppression and Photocarcinogenesis Affect DNA Repair

Stem Cells with Neural Crest Characteristics Derived from the Bulge Region of Cultured Human Hair Follicles

Letters to the Editor

Indoleamine 2,3-Dioxygenase+ Cells Correspond to the BDCA2+ Plasmacytoid Dendritic Cells in Human Melanoma Sentinel Nodes

Lack of Correlation between IGFBP7 Expression and BRAF Mutational Status in Melanoma

October 8 2009

Review

Molecular Dissection of Psoriasis: Integrating Genetics and Biology

Original Articles

Vitamin D Production after UVB Exposure Depends on Baseline Vitamin D and Total Cholesterol but Not on Skin Pigmentation

Sequential Intramolecular Epitope Spreading of Humoral Responses to Human BPAG2 in a Transgenic Model

IRF4 Gene Rearrangements Define a Subgroup of CD30-Positive Cutaneous T-Cell Lymphoma: A Study of 54 Cases

A TGF-Responsive Gene Signature Is Associated with a Subset of Diffuse Scleroderma with Increased Disease Severity

Psoriasis May Not be an Independent Risk Factor for Acute Ischemic Heart Disease Hospitalizations: Results of a Large Population-Based Dutch Cohort

Extracellular Adherence Protein of Staphylococcus aureus Suppresses Disease by Inhibiting T-Cell Recruitment in a Mouse Model of Psoriasis

Letters to the Editor

Formation of Free Radicals in Human Skin during Irradiation with Infrared Light

Dermal Nitrite Application Enhances Global Nitric Oxide Availability: New Therapeutic Potential for Immunomodulation?

Staphylococcus aureus Extracellular Protease Causes Epidermal Barrier Dysfunction

Specific Immunological Response to Budesonide in a Patient with Delayed-Type Hypersensitivity Reaction

Somatic Mutation of Epidermal Growth Factor Receptor in a Small Subset of Cutaneous Squamous Cell Carcinoma

Biosynthesis of Dihydrotestosterone by a Pathway that Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line

Response to Imatinib Mesylate Depends on the Presence of the V559A-Mutated KIT Oncogene

October 1 2009

Original Article

Engineered Human Skin Substitutes Undergo Large-Scale Genomic Reprogramming and Normal Skin-Like Maturation after Transplantation to Athymic Mice

Letter to the Editor

Methylation of PTEN as a Prognostic Factor in Malignant Melanoma of the Skin

September 24 2009

Molecular Analysis of Tumor-Promoting CD8⁺ T Cells in Two-Stage Cutaneous Chemical Carcinogenesis

Alterations of the Cell-Cycle Inhibitors p27^KIP1 and p16^INK4a Are Frequent in Blastic Plasmacytoid Dendritic Cell Neoplasms

The Histamine H₄ Receptor Mediates Inflammation and Pruritus in Th2-Dependent Dermal Inflammation

Pediatric Mastocytosis Is a Clonal Disease Associated with D⁸¹⁶V and Other Activating c-KIT Mutations

Pemphigus Vulgaris in White Europeans Is Linked with HLA Class II Allele HLA DRB1^1454 but Not DRB1^1401

Indoleamine 2,3-Dioxygenase⁺ Cells Correspond to the BDCA2⁺ Plasmacytoid Dendritic Cells in Human Melanoma Sentinel Nodes