Original Article

Journal of Investigative Dermatology (1978) 71, 382–384; doi:10.1111/1523-1747.ep12556814

New Method for Assessing Epidermal Wound Healing: The Effects of Triamcinolone Acetonide and Polyethelene Film Occlusion

William H Eaglstein and Patricia M Mertz

University of Miami School of Medicine, Department of Dermatology, Miami, Florida, U.S.A.

Received 6 February 1978; Accepted 13 June 1978.

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Abstract

Epidermal healing of superficial, excised wounds in domestic white pigs was evaluated visually and histologically after separation of the epidermis and dermis. The visual determination of epidermal healing correlated well with the histologic studies of surface re-epithelialization. Wounds healed 40% faster when occluded with polyethelene film. Topical triamcinolone acetonide treatment delayed healing (62% slower than control).

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References

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