Original Article

Journal of Investigative Dermatology (1972) 58, 103–108; doi:10.1111/1523-1747.ep12538894

THE HISTOPATHOLOGY OF EXPERIMENTAL PINTA IN THE CHIMPANZEE

Francis W Chandler Jr1, Arnold F Kaufmann2 and U S G Kuhn III1

  1. 1Venereal Disease Research Laboratory, Venereal Disease Program, State and Community Services Division, Center for Disease Control, Health Services, and Mental Health Administration, Public Health Service, U.S. Department of Health, Atlanta, GA 30333
  2. 2Chief Bacterial Zooneses Section, Bacterial Diseases Branch, Epidemiology Program, CDC, HSMHA, PHS, HEW, Atlanta, GA 30333

Received 15 September 1971; Accepted 17 September 1971.

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Abstract

Pinta lesions in various stages of development from experimentally infected chimpanzees were subjected to histopathologic examination. Both early lesions and lesions of long duration were strikingly similar to the corresponding lesions in man. However, observed differences in the chimpanzee lesions included the demonstration of Treponema carateum in the upper dermis, a location in which they are rarely found in man. The endstage of chimpanzee pinta was hyperpigmentation or normal pigmentation of the affected area as opposed to irreversible hypopigmentation more commonly seen in man.

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References

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