Meeting Paper

The Journal of Investigative Dermatology (1967) 49, 526–532; doi:10.1038/jid.1967.78

Fatty Acids of Surface Lipids from Uninvolved Skin in Psoriasis1

This work was supported by a grant from the John A. Hartford Foundation.

Presented before the 28th Annual Meeting of the Society for Investigative Dermatology, June 18–20, 1967, Atlantic City, New Jersey.

David I Wilkinson PhD and Eugene M Farber MD

1 From the Department of Dermatology, Stanford University School of Medicine, Palo Alto, California.

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References

  1. Rothman, S.: Abnormalities in the chemical composition of the skin surface film in psoriasis. Arch. Derm. (Chicago), 62: 814, 1950.
  2. Wilkinson, D. I. and Farber, E. M.: Free and esterified sterols in surface lipids from uninvolved skin in psoriasis. J. Invest. Derm., 48: 249, 1967.
  3. Herrmann, F. M., Scher, R., Coon, W. M. and Mandol, L.: The acid number of the lipids on the intact and stripped skin surface in psoriatics. J. Invest. Derm., 35: 47, 1960.
  4. Coon, W M., Herrmann, F. M. and Mandol, L.: Acid number of skin surface lipids in psoriasis. Arch. Derm. (Chicago), 83: 619, 1961.
  5. Wheatley, V. R.: The lipid components of the psoriatic skin. Proc. of the XII International Congress of Dermatology, 1962, Vol. 1, p. 157.
  6. Coon, W. M., Wheatley, V. R., Herrmann, F. and Mandol, L.: Free fatty acids of the skin surface and barrier zone in normal and abnormal keratinization. J. Invest. Derm., 41: 259, 1963.
  7. Duncombe, W. G.: The calorimetric microdetermination of longchain fatty acids. Biochem. J., 85: 7, 1963.
  8. Marsh, J. B. and Weinstein, D. B.: Simple charring method for determination of lipids. J. Lipid Res., 7: 574, 1966. | PubMed |
  9. Nicholaides, N. and Foster, R.C.: Esters in human hair fat. J. Amer. Oil Chem. Soc, 33: 404, 1956. | ChemPort |
  10. Wilkinson, D. I.: Psoriasis and dietary fat: The fatty acid composition of surface and scale (ether-soluble) lipids. J. Invest. Derm., 47: 185, 1966. | PubMed | ChemPort |
  11. Vandenheuvel, F. A., Hinderks, G. J., Nixon, J. C. and Layng, W. G.: Precise ultramicro determinations of steroid hormones by combined TLC and GLC analysis. J. Amer. Oil. Chem. Soc, 42: 283, 1965.
  12. Feldman, G. L. and Rouser, G.: Ultramicro fatty acid analysis of polar lipids : Gas-Liquid chromatography after column and thinlayer chromatography separation. J. Amer. Oil Chem. Soc, 42: 290, 1965.
  13. Vandenheuvel, F. A.: Quantitative analysis of submicrogram amounts of high boiling compounds by flame ionization GLC. Anal. Chem., 35: 1186, 1963.
  14. Herrmann, F. and Prose, P. H.: Studies on the ethersoluble substances on the human skin. I. Quantity and "replacement sum." J. Invest. Derm., 16: 217, 1951.
  15. Nicolaides, N.: Human skin surface lipidsorigin, composition, and possible function. In Montagna, W., Ellis, R. A., and Silver, A. F.: Advances in Biology of Skin. Vol. 4, Macmillan, New York, 1963.
  16. Scher, R., Herrmann, F., Coon, W. M. and Mandol, L.: The acid number of lipids on the stripped skin surface of patients with psoriasis and other parakeratotic plaques. Acta Dermatovener. (Stockholm), 42: 363, 1962.
  17. Harber, L.C., Herrmann, F., Mandol, L. and Sulzberger, M. B.: Lipid studies on the human skin surface by means of the monomolecular layer method. J. Invest. Derm., 29: 55, 1957.
  18. Lewis, C. A., Hayward, J. B. and MacKenna, R. M. B.: Saturated hydrocarbons in skin surface lipids. Brit. J. Derm., 77: 303, 1965. | PubMed | ChemPort |
  19. Kirk, J. E.: Hand washing. Acta Dermatovener. (Stockholm), 46: suppl. 57, 1966.
  20. Gara, A., Estrada, E., Rothman, S. and Lorincz, A. L.: Deficient cholesterol esterifying ability of lesion-free skin surfaces in psoriatic individuals. J. Invest. Derm., 43: 559, 1964.
  21. Wilkinson, D. I.: Unpublished experiments.
  22. Carruthers, C: Fatty acid composition of the phopshatide and triglyceride fractions of human epidermis. Proc Soc. Exper. Biol. Med., 115: 215, 1964.
  23. Nicolaides, N.: Skin lipids. II. Lipid class com-position of samples from various species and anatomical sites. J. Amer. Oil Chem. Soc, 42: 691, 1965. | ChemPort |

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