TABLE OF CONTENTS

Volume 129, Issue 6 (June 2009)

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Editorials

The Taiwanese Dermatological Association and the Taiwanese Society for Investigative Dermatology: Brief History and Current Status FREE

Hsin-Su Yu, Cheng-Che E Lan and Li-Fang Wang

J Invest Dermatol 129: 1313-1314; doi:10.1038/jid.2009.101

Research Snippets FREE

J Invest Dermatol 129: 1316; doi:10.1038/jid.2009.110

Editors' Picks FREE

J Invest Dermatol 129: 1317; doi:10.1038/jid.2009.100

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Journal Club

Progression of NRAS and BRAF Mutations in Cutaneous Melanoma FREE

Ritchie Rosso, Yvonne Romagosa and Robert S Kirsner

J Invest Dermatol 129: 1318; doi:10.1038/jid.2009.107

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Commentaries

Autosomal Recessive Congenital Ichthyosis

Judith Fischer

J Invest Dermatol 129: 1319-1321; doi:10.1038/jid.2009.57

See also: Original Article by Eckl et al.

Shedding Light on Proteolytic Cleavage of CD44: The Responsible Sheddase and Functional Significance of Shedding

Ivan Stamenkovic and Qin Yu

J Invest Dermatol 129: 1321-1324; doi:10.1038/jid.2009.13

See also: Original Article by Anderegg et al.

Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role?

Ralf Paus and Petra Arck

J Invest Dermatol 129: 1324-1326; doi:10.1038/jid.2009.111

See also: Original Article by Zhang et al.
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Reviews

The Biology of Cystatin M/E and its Cognate Target Proteases

Patrick L J M Zeeuwen, Tsing Cheng and Joost Schalkwijk

J Invest Dermatol 129: 1327-1338; advance online publication, March 5, 2009; doi:10.1038/jid.2009.40

The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis

Antonella Di Cesare, Paola Di Meglio and Frank O Nestle

J Invest Dermatol 129: 1339-1350; advance online publication, March 26, 2009; doi:10.1038/jid.2009.59

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Original Articles

Cell Biology

Mcl-1 Functions as Major Epidermal Survival Protein Required for Proper Keratinocyte Differentiation

Leonid A Sitailo, Anita Jerome-Morais and Mitchell F Denning

J Invest Dermatol 129: 1351-1360; doi:10.1038/jid.2008.363

The Relationship between the Aging- and Photo-Dependent T414G Mitochondrial DNA Mutation with Cellular Senescence and Reactive Oxygen Species Production in Cultured Skin Fibroblasts

Matthew J Birket, João F Passos, Thomas von Zglinicki and Mark A Birch-Machin

J Invest Dermatol 129: 1361-1366; advance online publication, December 4, 2008; doi:10.1038/jid.2008.373

Vitamin D Receptor and Coactivators SRC2 and 3 Regulate Epidermis-Specific Sphingolipid Production and Permeability Barrier Formation

Yuko Oda, Yoshikazu Uchida, Sam Moradian, Debra Crumrine, Peter M Elias and Daniel D Bikle

J Invest Dermatol 129: 1367-1378; advance online publication, December 4, 2008; doi:10.1038/jid.2008.380

Reevaluation of the Normal Epidermal Calcium Gradient, and Analysis of Calcium Levels and ATP Receptors in Hailey–Hailey and Darier Epidermis

Pekka T Leinonen, Päivi M Hägg, Sirkku Peltonen, Eeva-Mari Jouhilahti, Jukka Melkko, Timo Korkiamäki, Aarne Oikarinen and Juha Peltonen

J Invest Dermatol 129: 1379-1387; advance online publication, December 4, 2008; doi:10.1038/jid.2008.381

Elevated Dietary Magnesium Prevents Connective Tissue Mineralization in a Mouse Model of Pseudoxanthoma Elasticum (Abcc6 -/-)

Jennifer LaRusso, Qiaoli Li, Qiujie Jiang and Jouni Uitto

J Invest Dermatol 129: 1388-1394; advance online publication, January 1, 2009; doi:10.1038/jid.2008.391

Induction of SREBP-1c mRNA by Differentiation and LXR Ligand in Human Keratinocytes

Ai Yokoyama, Makoto Makishima, Mihwa Choi, Yoshitake Cho, Shigeru Nishida, Yuichi Hashimoto and Tadashi Terui

J Invest Dermatol 129: 1395-1401; advance online publication, February 26, 2009; doi:10.1038/jid.2009.15

Connective Tissue

TIA Nuclear Proteins Regulate the Alternate Splicing of Lysyl Hydroxylase 2

Heather N Yeowell, Linda C Walker, David M Mauger, Puneet Seth and Mariano A Garcia-Blanco

J Invest Dermatol 129: 1402-1411; advance online publication, December 25, 2008; doi:10.1038/jid.2008.386

Increased Hyaluronan Production and Decreased E-Cadherin Expression by Cytokine-Stimulated Keratinocytes Lead to Spongiosis Formation

Tomoyuki Ohtani, Ai Memezawa, Ryuhei Okuyama, Tetsuya Sayo, Yoshinori Sugiyama, Shintaro Inoue and Setsuya Aiba

J Invest Dermatol 129: 1412-1420; advance online publication, January 1, 2009; doi:10.1038/jid.2008.394

Genetics

Molecular Analysis of 250 Patients with Autosomal Recessive Congenital Ichthyosis: Evidence for Mutation Hotspots in ALOXE3 and Allelic Heterogeneity in ALOX12B

Katja-Martina Eckl, Silvia de Juanes, Janine Kurtenbach, Marc Nätebus, Jenny Lugassy, Vinzenz Oji, Heiko Traupe, Marie-Luise Preil, Francisco Martínez, Josef Smolle, Avikam Harel, Peter Krieg, Eli Sprecher and Hans C Hennies

J Invest Dermatol 129: 1421-1428; advance online publication, January 8, 2009; doi:10.1038/jid.2008.409

See also: Commentary by Fischer
Development of an Ichthyosiform Phenotype in Alox12b-Deficient Mouse Skin Transplants

Silvia de Juanes, Nikolas Epp, Susanne Latzko, Mareen Neumann, Gerhard Fürstenberger, Ingrid Hausser, Hans-Jürgen Stark and Peter Krieg

J Invest Dermatol 129: 1429-1436; advance online publication, January 1, 2009; doi:10.1038/jid.2008.410

Immunology/Infection

Regulatory T Cells Control VEGF-Dependent Skin Inflammation

Ingrid Teige, Henning Hvid, Lars Svensson, Peter Helding Kvist and Kåre Kemp

J Invest Dermatol 129: 1437-1445; advance online publication, November 27, 2008; doi:10.1038/jid.2008.375

Keratinocytes/Epidermis

Highly Complex Peptide Aggregates of the S100 Fused-Type Protein Hornerin Are Present in Human Skin

Zhihong Wu, Ulf Meyer-Hoffert, Katrin Reithmayer, Ralf Paus, Britta Hansmann, Yinghong He, Joachim Bartels, Regine Gläser, Jürgen Harder and Jens-Michael Schröder

J Invest Dermatol 129: 1446-1458; advance online publication, November 20, 2008; doi:10.1038/jid.2008.370

Dual Role of COUP-TF-Interacting Protein 2 in Epidermal Homeostasis and Permeability Barrier Formation

Olga Golonzhka, Xiaobo Liang, Nadia Messaddeq, Jean-Marc Bornert, Adam L Campbell, Daniel Metzger, Pierre Chambon, Gitali Ganguli-Indra, Mark Leid and Arup K Indra

J Invest Dermatol 129: 1459-1470; advance online publication, December 18, 2008; doi:10.1038/jid.2008.392

Melanocytes/Melanoma

ADAM10 Is the Constitutive Functional Sheddase of CD44 in Human Melanoma Cells

Ulf Anderegg, Thea Eichenberg, Tanja Parthaune, Christian Haiduk, Anja Saalbach, Linda Milkova, Andreas Ludwig, Jens Grosche, Marco Averbeck, Carl Gebhardt, Verena Voelcker, Jonathan P Sleeman and Jan C Simon

J Invest Dermatol 129: 1471-1482; advance online publication, October 30, 2008; doi:10.1038/jid.2008.323

See also: Commentary by Stamenkovic & Yu
Frequencies of NRAS and BRAF Mutations Increase from the Radial to the Vertical Growth Phase in Cutaneous Melanoma

Victoria R Greene, Marcella M Johnson, Elizabeth A Grimm and Julie A Ellerhorst

J Invest Dermatol 129: 1483-1488; doi:10.1038/jid.2008.374

Inulavosin, a Melanogenesis Inhibitor, Leads to Mistargeting of Tyrosinase to Lysosomes and Accelerates its Degradation

Hideaki Fujita, Tomonori Motokawa, Takayuki Katagiri, Sadaki Yokota, Akitsugu Yamamoto, Masaru Himeno and Yoshitaka Tanaka

J Invest Dermatol 129: 1489-1499; advance online publication, December 25, 2008; doi:10.1038/jid.2008.376

Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide

Tobias Sinnberg, Konstantinos Lasithiotakis, Heike Niessner, Birgit Schittek, Keith T Flaherty, Dagmar Kulms, Evelyn Maczey, Minia Campos, Jeannette Gogel, Claus Garbe and Friedegund Meier

J Invest Dermatol 129: 1500-1515; advance online publication, December 11, 2008; doi:10.1038/jid.2008.379

Loss of Class III beta-Tubulin Induced by Histone Deacetylation Is Associated with Chemosensitivity to Paclitaxel in Malignant Melanoma Cells

Kiyomi Akasaka, Chihaya Maesawa, Masahiko Shibazaki, Fumihiko Maeda, Kazuhiro Takahashi, Toshihide Akasaka and Tomoyuki Masuda

J Invest Dermatol 129: 1516-1526; advance online publication, January 1, 2009; doi:10.1038/jid.2008.406

Neurobiology

Development of Alopecia Areata Is Associated with Higher Central and Peripheral Hypothalamic–Pituitary–Adrenal Tone in the Skin Graft Induced C3H/HeJ Mouse Model

Xingqi Zhang, Mei Yu, Wayne Yu, Joanne Weinberg, Jerry Shapiro and Kevin J McElwee

J Invest Dermatol 129: 1527-1538; advance online publication, November 20, 2008; doi:10.1038/jid.2008.371

See also: Commentary by Paus & Arck

Photobiology

The Role of Interleukin-6 in UVA Protection against UVB-Induced Immunosuppression

Vivienne E Reeve, Rex M Tyrrell, Munif Allanson, Diane Domanski and Lynette Blyth

J Invest Dermatol 129: 1539-1546; advance online publication, December 25, 2008; doi:10.1038/jid.2008.377

Tumor Biology

Array-CGH Reveals Recurrent Genomic Changes in Merkel Cell Carcinoma Including Amplification of L-Myc

Kelly G Paulson, Bianca D Lemos, Bin Feng, Natalia Jaimes, Pablo F Peñas, Xiaohui Bi, Elizabeth Maher, Lisa Cohen, J Helen Leonard, Scott R Granter, Lynda Chin and Paul Nghiem

J Invest Dermatol 129: 1547-1555; advance online publication, November 20, 2008; doi:10.1038/jid.2008.365

Epstein-Barr Virus in Cutaneous T-Cell Lymphomas: Evaluation of the Viral Presence and Significance in Skin and Peripheral Blood

Mauro Novelli, Chiara Merlino, Renata Ponti, Massimiliano Bergallo, Pietro Quaglino, Irene Cambieri, Alessandra Comessatti, Francesca Sidoti, Cristina Costa, Daniele Corino, Rossana Cavallo, Alessandro Negro Ponzi, Maria T Fierro and Maria G Bernengo

J Invest Dermatol 129: 1556-1561; advance online publication, January 8, 2009; doi:10.1038/jid.2008.396

Single Nucleotide Polymorphism Array Analysis Defines a Specific Genetic Fingerprint for Well-Differentiated Cutaneous SCCs

Karin J Purdie, Catherine A Harwood, Abha Gulati, Tracy Chaplin, Sally R Lambert, Rino Cerio, Gavin P Kelly, Jean-Baptiste Cazier, Bryan D Young, Irene M Leigh and Charlotte M Proby

J Invest Dermatol 129: 1562-1568; advance online publication, January 8, 2009; doi:10.1038/jid.2008.408

Wound Healing

Chemokine-Mediated Migration of Skin-Derived Stem Cells: Predominant Role for CCL5/RANTES

Kim L Kroeze, Wouter J Jurgens, Behrouz Z Doulabi, Florine J van Milligen, Rik J Scheper and Susan Gibbs

J Invest Dermatol 129: 1569-1581; advance online publication, January 1, 2009; doi:10.1038/jid.2008.405

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Letters to the Editor

Comment on: "Reflectance Spectrophotometer: the Dermatologist's Sphygmomanometer for Skin Aging?"

Francisco J González

J Invest Dermatol 129: 1582-1583; doi:10.1038/jid.2008.436

Response to González

Lynn K Pershing, Laurence J Meyer and Sancy L Leachman

J Invest Dermatol 129: 1583-1584; doi:10.1038/jid.2008.437

Independent Evaluation of a Commercial Test for "Autoimmune" Urticaria in Normal and Chronic Urticaria Subjects

John A Eckman, Robert G Hamilton and Sarbjit S Saini

J Invest Dermatol 129: 1584-1586; advance online publication, January 8, 2009; doi:10.1038/jid.2008.416

Polyclonality of Multiple Sporadic Basal Cell Carcinomas

Ellen Heitzer, Franz Quehenberger and Peter Wolf

J Invest Dermatol 129: 1586-1589; advance online publication, January 8, 2009; doi:10.1038/jid.2008.411

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Errata/Corrigendum

High-Mobility Group Box 1 Protein in Human and Murine Skin: Involvement in Wound Healing FREE

J Invest Dermatol 129: 1590; doi:10.1038/jid.2008.326

Antibodies Elicited by Inactivated Propionibacterium acnes-Based Vaccines Exert Protective Immunity and Attenuate the IL-8 Production in Human Sebocytes: Relevance to Therapy for Acne Vulgaris FREE

J Invest Dermatol 129: 1590; doi:10.1038/jid.2008.355

Basophil Phenotypes in Chronic Idiopathic Urticaria in Relation to Disease Activity and Autoantibodies FREE

J Invest Dermatol 129: 1590; doi:10.1038/jid.2009.29

The Angiogenesis Inhibitor Thrombospondin-1 Inhibits Acute Cutaneous Hypersensitivity Reactions FREE

J Invest Dermatol 129: 1591; doi:10.1038/jid.2009.87

Primary Cutaneous T-Cell Lymphomas Do Not Show Specific NAV3 Gene Deletion or Translocation FREE

J Invest Dermatol 129: 1591; doi:10.1038/jid.2009.28

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