TABLE OF CONTENTS

Volume 129, Issue 4 (April 2009)

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Editorials

Research Snippets FREE

J Invest Dermatol 129: 812; doi:10.1038/jid.2009.53

Editors' Picks FREE

J Invest Dermatol 129: 813; doi:10.1038/jid.2009.38

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Journal Club

Defense of the Skin with LL-37 FREE

Navid Bouzari, Nancy Kim and Robert S Kirsner

J Invest Dermatol 129: 814; doi:10.1038/jid.2009.37

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Commentaries

Building Complex Tissues: High-Throughput Screening for Molecules Required in Hair Engineering

Lily F Lee and Cheng-Ming Chuong

J Invest Dermatol 129: 815-817; doi:10.1038/jid.2008.434

See also: Original Article by Havlickova et al.

Ectodysplasin Signaling in Cutaneous Appendage Development: Dose, Duration, and Diversity

Denis J Headon

J Invest Dermatol 129: 817-819; doi:10.1038/jid.2008.426

See also: Original Article by Cui et al.

New Aspects of Nitrite Homeostasis in Human Skin

Christian Opländer and Christoph V Suschek

J Invest Dermatol 129: 820-822; doi:10.1038/jid.2009.11

See also: Original Article by Mowbray et al.

Bullous Pemphigoid: A Prototypical Antibody-Mediated Organ-Specific Autoimmune Disease

Cassian Sitaru

J Invest Dermatol 129: 822-824; doi:10.1038/jid.2009.12

See also: Original Article by Iwata et al.

Antimicrobial Peptides and Suppression of Apoptosis in Human Skin

Michael Zasloff

J Invest Dermatol 129: 824-826; doi:10.1038/jid.2008.455

See also: Original Article by Chamorro et al.
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Review Article

Genetic Variations in Cytokines and Cytokine Receptors Associated with Psoriasis Found by Genome-Wide Association

Kristina Callis Duffin and Gerald G Krueger

J Invest Dermatol 129: 827-833; advance online publication, October 2, 2008; doi:10.1038/jid.2008.308

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Original Articles

Cell Biology

Enzyme-Independent NO Stores in Human Skin: Quantification and Influence of UV Radiation

Megan Mowbray, Sara McLintock, Rebecca Weerakoon, Natalia Lomatschinsky, Sarah Jones, Adriano G Rossi and Richard B Weller

J Invest Dermatol 129: 834-842; advance online publication, September 25, 2008; doi:10.1038/jid.2008.296

See also: Commentary by Opländer & Suschek

Connective Tissue

Collagen Synthesis Is Suppressed in Dermal Fibroblasts by the Human Antimicrobial Peptide LL-37

Hyun Jeong Park, Dae Ho Cho, Hee Jung Kim, Jun Young Lee, Baik Kee Cho, Sa Ik Bang, Sang Yong Song, Kenshi Yamasaki, Anna Di Nardo and Richard L Gallo

J Invest Dermatol 129: 843-850; advance online publication, October 16, 2008; doi:10.1038/jid.2008.320

Cytokine Profiling and Stat3 Phosphorylation in Epithelial–Mesenchymal Interactions between Keloid Keratinocytes and Fibroblasts

Cheh P Lim, Toan T Phan, Ivor J Lim and Xinmin Cao

J Invest Dermatol 129: 851-861; advance online publication, November 27, 2008; doi:10.1038/jid.2008.337

Genetics

Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing

Thomas Alef, Serena Torres, Ingrid Hausser, Dieter Metze, Ümit Türsen, Gilles G Lestringant and Hans Christian Hennies

J Invest Dermatol 129: 862-869; advance online publication, October 9, 2008; doi:10.1038/jid.2008.311

Connexin Mutations Causing Skin Disease and Deafness Increase Hemichannel Activity and Cell Death when Expressed in Xenopus Oocytes

Jack R Lee, Adam M DeRosa and Thomas W White

J Invest Dermatol 129: 870-878; advance online publication, November 6, 2008; doi:10.1038/jid.2008.335

Immunology/Infection

Role of CCL17 in the Generation of Cutaneous Inflammatory Reactions in Hu-PBMC-SCID Mice Grafted with Human Skin

Jules Gilet, Ying Chang, Cécile Chenivesse, Benjamin Legendre, Han Vorng, Catherine Duez, Benoît Wallaert, Henri Porte, Stéphanie Senechal and Anne Tsicopoulos

J Invest Dermatol 129: 879-890; advance online publication, November 13, 2008; doi:10.1038/jid.2008.333

Reduced Oxazolone-Induced Skin Inflammation in MAPKAP Kinase 2 Knockout Mice

Anne T Funding, Claus Johansen, Matthias Gaestel, Bo M Bibby, Louise L Lilleholt, Knud Kragballe and Lars Iversen

J Invest Dermatol 129: 891-898; advance online publication, November 6, 2008; doi:10.1038/jid.2008.322

Chronic Mouse Model of TMA-Induced Contact Hypersensitivity

Claudia Schneider, Wolf-Dietrich F Döcke, Thomas M Zollner and Lars Röse

J Invest Dermatol 129: 899-907; advance online publication, October 2, 2008; doi:10.1038/jid.2008.307

Keratinocytes/Epidermis

Disruption of Desmosome Assembly by Monovalent Human Pemphigus Vulgaris Monoclonal Antibodies FREE

Xuming Mao, Eun Jung Choi and Aimee S Payne

J Invest Dermatol 129: 908-918; advance online publication, November 27, 2008; doi:10.1038/jid.2008.339

IgG from Patients with Bullous Pemphigoid Depletes Cultured Keratinocytes of the 180-kDa Bullous Pemphigoid Antigen (Type XVII Collagen) and Weakens Cell Attachment

Hiroaki Iwata, Naoko Kamio, Yumi Aoyama, Yukari Yamamoto, Yoshiaki Hirako, Katsushi Owaribe and Yasuo Kitajima

J Invest Dermatol 129: 919-926; advance online publication, January 29, 2009; doi:10.1038/jid.2008.305

See also: Commentary by Sitaru
The "Caveolae Brake Hypothesis" and the Epidermal Barrier

Truus Roelandt, Christina Giddelo, Carol Heughebaert, Geertrui Denecker, Melanie Hupe, Debra Crumrine, Andy Kusuma, Marek Haftek, Diane Roseeuw, Wim Declercq, Kenneth R Feingold, Peter M Elias and Jean-Pierre Hachem

J Invest Dermatol 129: 927-936; advance online publication, November 13, 2008; doi:10.1038/jid.2008.328

The Human Antimicrobial Peptide LL-37 Suppresses Apoptosis in Keratinocytes FREE

Clara I Chamorro, Günther Weber, Alvar Grönberg, Andor Pivarcsi and Mona Ståhle

J Invest Dermatol 129: 937-944; advance online publication, October 16, 2008; doi:10.1038/jid.2008.321

See also: Commentary by Zasloff

Melanocytes/Melanoma

SOX9 and SOX10 but Not BRN2 Are Required for Nestin Expression in Human Melanoma Cells

Anna Flammiger, Robert Besch, Anthony L Cook, Tanja Maier, Richard A Sturm and Carola Berking

J Invest Dermatol 129: 945-953; advance online publication, October 16, 2008; doi:10.1038/jid.2008.316

Plexin C1, A Receptor for Semaphorin 7A, Inactivates Cofilin and Is a Potential Tumor Suppressor for Melanoma Progression

Glynis A Scott, Lindy A McClelland, Alex F Fricke and Anne Fender

J Invest Dermatol 129: 954-963; advance online publication, November 6, 2008; doi:10.1038/jid.2008.329

BH3 Mimetic ABT-737 and a Proteasome Inhibitor Synergistically Kill Melanomas through Noxa-Dependent Apoptosis

Leslie A Miller, Nathaniel B Goldstein, Widya U Johannes, Christine H Walton, Mayumi Fujita, David A Norris and Yiqun G Shellman

J Invest Dermatol 129: 964-971; advance online publication, November 6, 2008; doi:10.1038/jid.2008.327

Neurobiology

A Human Folliculoid Microsphere Assay for Exploring Epithelial– Mesenchymal Interactions in the Human Hair Follicle FREE

Blanka Havlickova, Tamás Bíró, Alessandra Mescalchin, Miriam Tschirschmann, Hans Mollenkopf, Albrecht Bettermann, Paolo Pertile, Roland Lauster, Enikö Bodó and Ralf Paus

J Invest Dermatol 129: 972-983; advance online publication, October 16, 2008; doi:10.1038/jid.2008.315

See also: Commentary by Lee & Chuong
Analysis of the Temporal Requirement for Eda in Hair and Sweat Gland Development

Chang-Yi Cui, Makoto Kunisada, Diana Esibizione, Eric G Douglass and David Schlessinger

J Invest Dermatol 129: 984-993; advance online publication, October 16, 2008; doi:10.1038/jid.2008.318

See also: Commentary by Headon

Photobiology

UVB and Proinflammatory Cytokines Synergistically Activate TNF-alpha Production in Keratinocytes through Enhanced Gene Transcription

Muhammad M Bashir, Meena R Sharma and Victoria P Werth

J Invest Dermatol 129: 994-1001; advance online publication, November 13, 2008; doi:10.1038/jid.2008.332

Long-Lasting Molecular Changes in Human Skin after Repetitive In Situ UV Irradiation

Michaela Brenner, Sergio G Coelho, Janusz Z Beer, Sharon A Miller, Rainer Wolber, Christoph Smuda and Vincent J Hearing

J Invest Dermatol 129: 1002-1011; advance online publication, October 23, 2008; doi:10.1038/jid.2008.325

Tumor Biology

Hotspot Mutation of Brahma in Non-Melanoma Skin Cancer

Fergal J Moloney, J Guy Lyons, Vanessa L Bock, Xiao X Huang, Matthew J Bugeja and Gary M Halliday

J Invest Dermatol 129: 1012-1015; advance online publication, October 16, 2008; doi:10.1038/jid.2008.319

Tumor-Associated Macrophage-Induced Invasion and Angiogenesis of Human Basal Cell Carcinoma Cells by Cyclooxygenase-2 Induction

Jeng-Wei Tjiu, Jau-Shiuh Chen, Chia-Tung Shun, Sung-Jan Lin, Yi-Hua Liao, Chia-Yu Chu, Tsen-Fang Tsai, Hsien-Ching Chiu, Yang-Shia Dai, Hiroyasu Inoue, Pan-Chyr Yang, Min-Liang Kuo and Shiou-Hwa Jee

J Invest Dermatol 129: 1016-1025; advance online publication, October 9, 2008; doi:10.1038/jid.2008.310

High beta-HPV DNA Loads and Strong Seroreactivity Are Present in Epidermodysplasia Verruciformis

Valentina Dell'Oste, Barbara Azzimonti, Marco De Andrea, Michele Mondini, Elisa Zavattaro, Giorgio Leigheb, Sönke J Weissenborn, Herbert Pfister, Kristina M Michael, Tim Waterboer, Michael Pawlita, Ada Amantea, Santo Landolfo and Marisa Gariglio

J Invest Dermatol 129: 1026-1034; advance online publication, October 16, 2008; doi:10.1038/jid.2008.317

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Letters to the Editor

Basophil Phenotypes in Chronic Idiopathic Urticaria in Relation to Disease Activity and Autoantibodies

Clive E H Grattan and Elena Borzova

J Invest Dermatol 129: 1035-1036; doi:10.1038/jid.2008.334

Response to Grattan et al.

John A Eckman, Robert G Hamilton and Sarbjit S Saini

J Invest Dermatol 129: 1036-1038; doi:10.1038/jid.2008.336

Isotretinoin Temporally Regulates Distinct Sets of Genes in Patient Skin

Amanda M Nelson, Wei Zhao, Kathryn L Gilliland, Andrea L Zaenglein, WenLei Liu and Diane M Thiboutot

J Invest Dermatol 129: 1038-1042; advance online publication, November 6, 2008; doi:10.1038/jid.2008.338

Heterozygous Null Alleles in Filaggrin Contribute to Clinical Dry Skin in Young Adults and the Elderly

Ann Sergeant, Linda E Campbell, Peter R Hull, Martin Porter, Colin N A Palmer, Frances J D Smith, W H Irwin McLean and Colin S Munro

J Invest Dermatol 129: 1042-1045; advance online publication, November 6, 2008; doi:10.1038/jid.2008.324

Circumscribed Palmo-Plantar Hypokeratosis: A Disease With Two Subtypes

Miki Tanioka, Aya Miyagawa-Hayashino, Toshiaki Manabe, Eiko Toichi, Yoshiki Miyachi and Kenzo Takahashi

J Invest Dermatol 129: 1045-1047; advance online publication, September 25, 2008; doi:10.1038/jid.2008.306

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