TABLE OF CONTENTS

Volume 129, Issue 3 (March 2009)

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Editorial

Research Snippets FREE

J Invest Dermatol 129: 522; doi:10.1038/jid.2009.2

Editors' Picks FREE

J Invest Dermatol 129: 523; doi:10.1038/jid.2009.7

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Journal Club

Epidermal Growth Factor Receptor Regulates Skin Nerve Outgrowth and Branching FREE

Robb Marchione, Nancy Kim and Robert S Kirsner

J Invest Dermatol 129: 524; doi:10.1038/jid.2008.462

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Meeting Report

Society for Investigative Dermatology Skin Disease Co-Morbidities Project Launch Conference Proceedings FREE

Heather Yarnall Schultz

J Invest Dermatol 129: 525-528; doi:10.1038/jid.2008.417

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Commentaries

Dysregulation of the mTOR Pathway Secondary to Mutations or a Hostile Microenvironment Contributes to Cancer and Poor Wound Healing

Richard A F Clark and Michelle Pavlis

J Invest Dermatol 129: 529-531; doi:10.1038/jid.2008.441

See also: Original Article by Goren et al.

A TR(I)P to Pruritus Research: Role of TRPV3 in Inflammation and Itch

Martin Steinhoff and Tamás Bíró

J Invest Dermatol 129: 531-535; doi:10.1038/jid.2008.440

See also: Original Article by Yoshioka et al.

Selection and Validation of Candidate Housekeeping Genes for Studies of Human Keratinocytes—Review and Recommendations

Michael Bär, Dorit Bär and Bodo Lehmann

J Invest Dermatol 129: 535-537; doi:10.1038/jid.2008.428

See also: Letter to the Editor by Minner & Poumay

Unexpected Autocrine Role of Vascular Endothelial Growth Factor in Squamous Cell Carcinoma

Jack L Arbiser

J Invest Dermatol 129: 538-540; doi:10.1038/jid.2008.427

See also: Original Article by Mirones et al.

Woolly Antics between the Sheaths

Desmond J Tobin

J Invest Dermatol 129: 540-542; doi:10.1038/jid.2008.429

See also: Original Article by Shimomura et al.
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Perspective

Eczema Genetics: Current State of Knowledge and Future Goals

Sara J Brown and W H Irwin McLean

J Invest Dermatol 129: 543-552; doi:10.1038/jid.2008.413

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Original Articles

Cell Biology

Mutations in the GGCX and ABCC6 Genes in a Family with Pseudoxanthoma Elasticum-Like Phenotypes

Qiaoli Li, Dorothy K Grange, Nicole L Armstrong, Alison J Whelan, Maria Y Hurley, Mark A Rishavy, Kevin W Hallgren, Kathleen L Berkner, Leon J Schurgers, Qiujie Jiang and Jouni Uitto

J Invest Dermatol 129: 553-563; advance online publication, September 18, 2008; doi:10.1038/jid.2008.271

Cadherin-Mediated Cell–Cell Contact Regulates Keratinocyte Differentiation

Joseph L Charest, Jean M Jennings, William P King, Andrew P Kowalczyk and Andrés J García

J Invest Dermatol 129: 564-572; advance online publication, August 28, 2008; doi:10.1038/jid.2008.265

Endogenous Galectin-3 Is Localized in Membrane Lipid Rafts and Regulates Migration of Dendritic Cells

Daniel K Hsu, Alexander I Chernyavsky, Huan-Yuan Chen, Lan Yu, Sergei A Grando and Fu-Tong Liu

J Invest Dermatol 129: 573-583; advance online publication, October 9, 2008; doi:10.1038/jid.2008.276

Calcium Ion Gradients and Dynamics in Cultured Skin Slices of Rat Hindpaw in Response to Stimulation with ATP

Moe Tsutsumi, Sumiko Denda, Kaori Inoue, Kazuyuki Ikeyama and Mitsuhiro Denda

J Invest Dermatol 129: 584-589; advance online publication, October 2, 2008; doi:10.1038/jid.2008.299

Connective Tissue

Cell Permeant Peptide Analogues of the Small Heat Shock Protein, HSP20, Reduce TGF-beta1-Induced CTGF Expression in Keloid Fibroblasts

Luciana B Lopes, Elizabeth J Furnish, Padmini Komalavilas, Charles R Flynn, Patricia Ashby, Adam Hansen, Daphne P Ly, George P Yang, Michael T Longaker, Alyssa Panitch and Colleen M Brophy

J Invest Dermatol 129: 590-598; advance online publication, September 11, 2008; doi:10.1038/jid.2008.264

Genetics

Seasonal Palmar Keratoderma in Erythropoietic Protoporphyria Indicates Autosomal Recessive Inheritance

S Alexander Holme, Sharon D Whatley, Andrew G Roberts, Alexander V Anstey, George H Elder, Russell D Ead, M Felicity Stewart, Peter M Farr, Helen M Lewis, Nicholas Davies, Marion I White, R Simon Ackroyd and Michael N Badminton

J Invest Dermatol 129: 599-605; advance online publication, September 11, 2008; doi:10.1038/jid.2008.272

Association of Skin Barrier Genes within the PSORS4 Locus Is Enriched in Singaporean Chinese with Early-Onset Psoriasis

Huijia Chen, Terry K L Toh, Ildiko Szeverenyi, Rick T H Ong, Colin T S Theng, W H Irwin McLean, Mark Seielstad and E Birgitte Lane

J Invest Dermatol 129: 606-614; advance online publication, September 11, 2008; doi:10.1038/jid.2008.273

Mechanisms of Loss of Heterozygosity in Neurofibromatosis Type 1-Associated Plexiform Neurofibromas

Katharina Steinmann, Lan Kluwe, Reinhard E Friedrich, Victor-Felix Mautner, David N Cooper and Hildegard Kehrer-Sawatzki

J Invest Dermatol 129: 615-621; advance online publication, September 18, 2008; doi:10.1038/jid.2008.274

Mutations in the Lipase H Gene Underlie Autosomal Recessive Woolly Hair/Hypotrichosis

Yutaka Shimomura, Muhammad Wajid, Lynn Petukhova, Lawrence Shapiro and Angela M Christiano

J Invest Dermatol 129: 622-628; advance online publication, October 2, 2008; doi:10.1038/jid.2008.290

See also: Commentary by Tobin
Further Genetic Evidence for Three Psoriasis-Risk Genes: ADAM33, CDKAL1, and PTPN22

Yonghong Li, Wilson Liao, Monica Chang, Steven J Schrodi, Nam Bui, Joseph J Catanese, Annie Poon, Nori Matsunami, Kristina P Callis-Duffin, Mark F Leppert, Anne M Bowcock, Pui-Yan Kwok, Gerald G Krueger and Ann B Begovich

J Invest Dermatol 129: 629-634; advance online publication, October 16, 2008; doi:10.1038/jid.2008.297

Immunology/Infection

Lack of Evidence for Activation of the Hedgehog Pathway in Psoriasis

Johann E Gudjonsson, Abhishek Aphale, Marina Grachtchouk, Jun Ding, Rajan P Nair, Timothy Wang, John J Voorhees, Andrzej A Dlugosz and James T Elder

J Invest Dermatol 129: 635-640; advance online publication, August 28, 2008; doi:10.1038/jid.2008.266

The Antimicrobial Protein Psoriasin (S100A7) Is Upregulated in Atopic Dermatitis and after Experimental Skin Barrier Disruption

Regine Gläser, Ulf Meyer-Hoffert, Jürgen Harder, Jesko Cordes, Maike Wittersheim, Julia Kobliakova, Regina Fölster-Holst, Ehrhardt Proksch, Jens-Michael Schröder and Thomas Schwarz

J Invest Dermatol 129: 641-649; advance online publication, August 28, 2008; doi:10.1038/jid.2008.268

Functional Characterization of IL-17F as a Selective Neutrophil Attractant in Psoriasis

Hideaki Watanabe, Mio Kawaguchi, Sawa Fujishima, Miyoko Ogura, Satoshi Matsukura, Hiroko Takeuchi, Motoi Ohba, Hirohiko Sueki, Fumio Kokubu, Nobuyuki Hizawa, Mitsuru Adachi, Shau-Ku Huang and Masafumi Iijima

J Invest Dermatol 129: 650-656; advance online publication, October 2, 2008; doi:10.1038/jid.2008.294

Auf1/Hnrnpd-Deficient Mice Develop Pruritic Inflammatory Skin Disease

Navid Sadri and Robert J Schneider

J Invest Dermatol 129: 657-670; advance online publication, October 2, 2008; doi:10.1038/jid.2008.298

Keratinocytes/Epidermis

Cytokine-Induced CEACAM1 Expression on Keratinocytes Is Characteristic for Psoriatic Skin and Contributes to a Prolonged Lifespan of Neutrophils

Massilva Rahmoun, Jean-Pierre Molès, Nathalie Pedretti, Marc Mathieu, Isabelle Fremaux, Nadia Raison-Peyron, Jean-Claude Lecron, Hans Yssel and Jérôme Pène

J Invest Dermatol 129: 671-681; advance online publication, October 9, 2008; doi:10.1038/jid.2008.303

Clinical Severity Correlates with Impaired Barrier in Filaggrin-Related Eczema

Ikue Nemoto-Hasebe, Masashi Akiyama, Toshifumi Nomura, Aileen Sandilands, WH Irwin McLean and Hiroshi Shimizu

J Invest Dermatol 129: 682-689; advance online publication, September 25, 2008; doi:10.1038/jid.2008.280

Neurobiology

The EGFR Is Required for Proper Innervation to the Skin

Adel Maklad, Jodi R Nicolai, Kyle J Bichsel, Jackie E Evenson, Tang-Cheng Lee, David W Threadgill and Laura A Hansen

J Invest Dermatol 129: 690-698; advance online publication, October 2, 2008; doi:10.1038/jid.2008.281

Photobiology

Repair of Sparfloxacin-Induced Photochemical DNA Damage In Vivo

Melanie Struwe, Karl-Otto Greulich, Elias Perentes, Hans-Jörg Martus, Willi Suter and Ulla Plappert-Helbig

J Invest Dermatol 129: 699-704; advance online publication, September 4, 2008; doi:10.1038/jid.2008.263

IL-10-Producing Langerhans Cells and Regulatory T Cells Are Responsible for Depressed Contact Hypersensitivity in Grafted Skin

Ryutaro Yoshiki, Kenji Kabashima, Kazunari Sugita, Kenji Atarashi, Takatoshi Shimauchi and Yoshiki Tokura

J Invest Dermatol 129: 705-713; advance online publication, October 9, 2008; doi:10.1038/jid.2008.304

Vascular Biology

Impact of the Gly573Ser Substitution in TRPV3 on the Development of Allergic and Pruritic Dermatitis in Mice

Takeshi Yoshioka, Kinichi Imura, Makoto Asakawa, Minoru Suzuki, Itsuki Oshima, Tsutomu Hirasawa, Tsuneaki Sakata, Tatsuya Horikawa and Akinori Arimura

J Invest Dermatol 129: 714-722; advance online publication, August 28, 2008; doi:10.1038/jid.2008.245

See also: Commentary by Steinhoff & Bíró
Iron Chelators and Hypoxia Mimetics Inhibit IFNbold gamma-Mediated Jak-STAT Signaling

Amy K Gira, Andrew P Kowalczyk, Yue Feng and Robert A Swerlick

J Invest Dermatol 129: 723-729; advance online publication, September 11, 2008; doi:10.1038/jid.2008.269

Complexity of VEGF Responses in Skin Carcinogenesis Revealed through Ex Vivo Assays Based on a VEGF-A Null Mouse Keratinocyte Cell Line

Isabel Mirones, Claudio J Conti, Jesús Martínez, Marta Garcia and Fernando Larcher

J Invest Dermatol 129: 730-741; advance online publication, September 25, 2008; doi:10.1038/jid.2008.292

See also: Commentary by Arbiser
Transgenic Expression of Interleukin-13 in the Skin Induces a Pruritic Dermatitis and Skin Remodeling

Tao Zheng, Min H Oh, Sun Y Oh, John T Schroeder, Adam B Glick and Zhou Zhu

J Invest Dermatol 129: 742-751; advance online publication, October 2, 2008; doi:10.1038/jid.2008.295

Wound Healing

Akt1 Controls Insulin-Driven VEGF Biosynthesis from Keratinocytes: Implications for Normal and Diabetes-Impaired Skin Repair in Mice

Itamar Goren, Elke Müller, Dana Schiefelbein, Paul Gutwein, Oliver Seitz, Josef Pfeilschifter and Stefan Frank

J Invest Dermatol 129: 752-764; advance online publication, July 31, 2008; doi:10.1038/jid.2008.230

See also: Commentary by Clark & Pavlis
Calmodulin-Like Protein Upregulates Myosin-10 in Human Keratinocytes and Is Regulated during Epidermal Wound Healing In Vivo

Richard D Bennett, Amy S Mauer, Mark R Pittelkow and Emanuel E Strehler

J Invest Dermatol 129: 765-769; advance online publication, September 25, 2008; doi:10.1038/jid.2008.288

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Letters to the Editor

Candidate Housekeeping Genes Require Evaluation before their Selection for Studies of Human Epidermal Keratinocytes

Frédéric Minner and Yves Poumay

J Invest Dermatol 129: 770-773; advance online publication, August 21, 2008; doi:10.1038/jid.2008.247

See also: Commentary by Bär et al.

Skin Equivalent and Natural Killer Cells: A New Model for Psoriasis and GVHD

Richard S Kalish, Marcia Simon, Robin Harrington, Alice B Gottlieb and Amos Gilhar

J Invest Dermatol 129: 773-776; advance online publication, September 11, 2008; doi:10.1038/jid.2008.285

Keratitis-Ichthyosis-Deafness Syndrome Caused by GJB2 Maternal Mosaicism

Matthias Titeux, Vanessa Mendonça, Audrey Décha, Elisabete Moreira, Sofia Magina, Ana Maia, Laetitia Lacaze-Buzy, José Enrique Mejía, Luís Torrão, Filipa Carvalho, Júlia Eça-Guimarães and Alain Hovnanian

J Invest Dermatol 129: 776-779; advance online publication, October 9, 2008; doi:10.1038/jid.2008.312

Hypothesis Letter: The Reason Sentinel and Lymph Node Dissections Do Not Improve Melanoma Mortality

James M Grichnik

J Invest Dermatol 129: 779-781; advance online publication, September 11, 2008; doi:10.1038/jid.2008.275

Absence of Germline Epimutation of the CDKN2A Gene in Familial Melanoma

Remco van Doorn, Willem H Zoutman and Nelleke A Gruis

J Invest Dermatol 129: 781-784; advance online publication, September 25, 2008; doi:10.1038/jid.2008.287

An Epinephrine-Dependent Mechanism for the Control of UV-Induced Pigmentation

Raja K Sivamani, Scott M Porter and R Rivkah Isseroff

J Invest Dermatol 129: 784-787; advance online publication, August 21, 2008; doi:10.1038/jid.2008.262

A New Paradigm for the Role of Aging in the Development of Skin Cancer

Davina A Lewis, Jeffrey B Travers and Dan F Spandau

J Invest Dermatol 129: 787-791; advance online publication, September 25, 2008; doi:10.1038/jid.2008.293

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Abstracts

Congres Annuel De Recherche Dermatologique (CARD) French-Speaking Congress of Dermatological Research Toulouse (France), 12–13 September 2008 FREE

J Invest Dermatol 129: 792-809; doi:10.1038/jid.2008.415

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