Clinical Snippets FREE

J Invest Dermatol 128: 1871; doi:10.1038/jid.2008.187

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Research Snippets FREE

J Invest Dermatol 128: 1872; doi:10.1038/jid.2008.195

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Proteolytically Active Allergens Cause Barrier Breakdown FREE

Truus Roelandt, Carol Heughebaert and Jean-Pierre Hachem

J Invest Dermatol 128: 1878-1880; doi:10.1038/jid.2008.168

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Langerhans Cell Dogma: Another Round of Rejections FREE

Mark C Udey and Amy S Rosenberg

J Invest Dermatol 128: 1881-1883; doi:10.1038/jid.2008.167

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Overexpression of Extracellular Epimorphin Leads to Impaired Epidermal Differentiation in HaCaT Keratinocytes FREE

Yoji Okugawa and Yohei Hirai

J Invest Dermatol 128: 1884-1893; advance online publication, February 14, 2008; doi:10.1038/jid.2008.22

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Expression of Uncoupling Proteins in Human Skin and Skin-Derived Cells FREE

Shinobu Mori, Naonobu Yoshizuka, Minoru Takizawa, Yoshinori Takema, Takatoshi Murase, Ichiro Tokimitsu and Masayuki Saito

J Invest Dermatol 128: 1894-1900; advance online publication, February 28, 2008; doi:10.1038/jid.2008.20

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A Protective Effect of Glutathione-S-Transferase GSTP1*Val¹⁰⁵ against Polymorphic Light Eruption FREE

Thomas P Millard, Anthony A Fryer and Jane M McGregor

J Invest Dermatol 128: 1901-1905; advance online publication, February 21, 2008; doi:10.1038/jid.2008.14

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Akt Blockade Downregulates Collagen and Upregulates MMP1 in Human Dermal Fibroblasts FREE

Andreea M Bujor, Jaspreet Pannu, Shizhong Bu, Edwin A Smith, Robin C Muise-Helmericks and Maria Trojanowska

J Invest Dermatol 128: 1906-1914; advance online publication, March 6, 2008; doi:10.1038/jid.2008.39

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Rescue of Migratory Defects of Ehlers–Danlos Syndrome Fibroblasts In Vitro by Type V Collagen but not Insulin-Like Binding Protein-1 FREE

Simona Viglio, Nicoletta Zoppi, Antonella Sangalli, Angelo Gallanti, Sergio Barlati, Monica Mottes, Marina Colombi and Maurizia Valli

J Invest Dermatol 128: 1915-1919; advance online publication, February 28, 2008; doi:10.1038/jid.2008.33

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Increased Frequency of Ig Heavy-Chain HS1,2-A Enhancer *2 Allele in Dermatitis Herpetiformis, Plaque Psoriasis, and Psoriatic Arthritis FREE

Rossella Cianci, Vincenzo Giambra, Claudia Mattioli, Maria Esposito, Giovanni Cammarota, Graziella Scibilia, Giuseppe Magazzù, Ambrogio Orlando, Giancarlo Sandri, Luca Bianchi, Giovanni Battista Gasbarrini, Franco Pandolfi and Domenico Frezza

J Invest Dermatol 128: 1920-1924; advance online publication, March 6, 2008; doi:10.1038/jid.2008.40

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Genetic Variation in Efflux Transporters Influences Outcome to Methotrexate Therapy in Patients with Psoriasis FREE

Richard B Warren, Rhodri Ll Smith, Emanuela Campalani, Steve Eyre, Catherine H Smith, Jonathan N W N Barker, Jane Worthington and Christopher E M Griffiths

J Invest Dermatol 128: 1925-1929; advance online publication, February 7, 2008; doi:10.1038/jid.2008.16

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Mite and Cockroach Allergens Activate Protease-Activated Receptor 2 and Delay Epidermal Permeability Barrier Recovery FREE

Se Kyoo Jeong, Hyun Jeong Kim, Jong-Kyung Youm, Sung Ku Ahn, Eung Ho Choi, Myung Hyun Sohn, Kyu-Earn Kim, Jeong Hee Hong, Dong Min Shin and Seung Hun Lee

J Invest Dermatol 128: 1930-1939; advance online publication, February 28, 2008; doi:10.1038/jid.2008.13

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PPAR Is a Type 1 IFN Target Gene and Inhibits Apoptosis in T Cells FREE

Nadya al Yacoub, Malgorzata Romanowska, Sybille Krauss, Susann Schweiger and John Foerster

J Invest Dermatol 128: 1940-1949; advance online publication, February 28, 2008; doi:10.1038/jid.2008.32

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Langerhans Cells Are Not Required for Efficient Skin Graft Rejection FREE

Jagdeep S Obhrai, Martin Oberbarnscheidt, Na Zhang, Daniel L Mueller, Warren D Shlomchik, Fadi G Lakkis, Mark J Shlomchik and Daniel H Kaplan

J Invest Dermatol 128: 1950-1955; advance online publication, March 13, 2008; doi:10.1038/jid.2008.52

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Basophil Phenotypes in Chronic Idiopathic Urticaria in Relation to Disease Activity and Autoantibodies FREE

John A Eckman, Robert G Hamilton, Laura M Gober, Patricia M Sterba and Sarbjit S Saini

J Invest Dermatol 128: 1956-1963; advance online publication, March 20, 2008; doi:10.1038/jid.2008.55

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Critical Role of HIF-1 in Keratinocyte Defense against Bacterial Infection FREE

Carole Peyssonnaux, Adam T Boutin, Annelies S Zinkernagel, Vivekanand Datta, Victor Nizet and Randall S Johnson

J Invest Dermatol 128: 1964-1968; advance online publication, March 6, 2008; doi:10.1038/jid.2008.27

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FR255734, a Humanized, Fc-Silent, Anti-CD28 Antibody, Improves Psoriasis in the SCID Mouse-Psoriasis Xenograft Model FREE

Siba P Raychaudhuri, Smriti Kundu-Raychaudhuri, Kouichi Tamura, Taro Masunaga, Kaori Kubo, Kaori Hanaoka, Wen-Yue Jiang, Leonore A Herzenberg and Leonard A Herzenberg

J Invest Dermatol 128: 1969-1976; advance online publication, March 13, 2008; doi:10.1038/jid.2008.38

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Lack of Functionally Active Melan-A_26–35-Specific T Cells in the Blood of HLA-A2⁺ Vitiligo Patients FREE

Sylvia Adams, Michelle A Lowes, David W O'Neill, Stephen Schachterle, Pedro Romero and Nina Bhardwaj

J Invest Dermatol 128: 1977-1980; advance online publication, March 13, 2008; doi:10.1038/jid.2008.31

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Profiling Motility Signal-Specific Genes in Primary Human Keratinocytes FREE

Chieh-Fang Cheng, Jianhua Fan, Balaji Bandyopahdhay, Dennis Mock, Shengxi Guan, Mei Chen, David T Woodley and Wei Li

J Invest Dermatol 128: 1981-1990; advance online publication, March 6, 2008; doi:10.1038/jid.2008.34

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Restoration of the Expression of Transports Associated with Antigen Processing in Human Malignant Melanoma Increases Tumor-Specific Immunity FREE

Juan Tao, Yan Li, Ye-Qiang Liu, Lin Wang, Jing Yang, Jing Dong, Yan Wu, Guan-Xin Shen and Ya-Ting Tu

J Invest Dermatol 128: 1991-1996; advance online publication, April 3, 2008; doi:10.1038/jid.2008.10

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STAT3 as a Biomarker of Progression in Atypical Nevi of Patients with Melanoma: Dose–Response Effects of Systemic IFN Therapy FREE

Wenjun Wang, Howard D Edington, Uma N M Rao, Drazen M Jukic, Hong Wang, Janice M Shipe-Spotloe and John M Kirkwood

J Invest Dermatol 128: 1997-2002; advance online publication, February 28, 2008; doi:10.1038/jid.2008.26

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Phospho-ERK Staining Is a Poor Indicator of the Mutational Status of BRAF and NRAS in Human Melanoma FREE

Roland Houben, Claudia S Vetter-Kauczok, Sonja Ortmann, Ulf R Rapp, Eva B Broecker and Juergen C Becker

J Invest Dermatol 128: 2003-2012; advance online publication, March 6, 2008; doi:10.1038/jid.2008.30

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Combined Inhibition of MAPK and mTOR Signaling Inhibits Growth, Induces Cell Death, and Abrogates Invasive Growth of Melanoma Cells FREE

Konstantinos G Lasithiotakis, Tobias W Sinnberg, Birgit Schittek, Keith T Flaherty, Dagmar Kulms, Evelyn Maczey, Claus Garbe and Friedegund E Meier

J Invest Dermatol 128: 2013-2023; advance online publication, March 6, 2008; doi:10.1038/jid.2008.44

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Distribution and Significance of Occult Intraepidermal Tumor Cells Surrounding Primary Melanoma FREE

Jeffrey P North, Toshiro Kageshita, Daniel Pinkel, Philip E LeBoit and Boris C Bastian

J Invest Dermatol 128: 2024-2030; advance online publication, March 6, 2008; doi:10.1038/jid.2008.41

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Neurotrophins and Their Receptors Stimulate Melanoma Cell Proliferation and Migration FREE

Francesca Truzzi, Alessandra Marconi, Roberta Lotti, Katiuscia Dallaglio, Lars E French, Barbara L Hempstead and Carlo Pincelli

J Invest Dermatol 128: 2031-2040; advance online publication, February 28, 2008; doi:10.1038/jid.2008.21

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HSP70i Accelerates Depigmentation in a Mouse Model of Autoimmune Vitiligo FREE

Cecele J Denman, James McCracken, Vidhya Hariharan, Jared Klarquist, Kepa Oyarbide-Valencia, José A Guevara-Patiño and I Caroline Le Poole

J Invest Dermatol 128: 2041-2048; advance online publication, March 13, 2008; doi:10.1038/jid.2008.45

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Computer-Based Classification of Dermoscopy Images of Melanocytic Lesions on Acral Volar Skin FREE

Hitoshi Iyatomi, Hiroshi Oka, M Emre Celebi, Koichi Ogawa, Giuseppe Argenziano, H Peter Soyer, Hiroshi Koga, Toshiaki Saida, Kuniaki Ohara and Masaru Tanaka

J Invest Dermatol 128: 2049-2054; advance online publication, March 6, 2008; doi:10.1038/jid.2008.28

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Xeroderma Pigmentosum-Variant Patients from America, Europe, and Asia FREE

Hiroki Inui, Kyu-Seon Oh, Carine Nadem, Takahiro Ueda, Sikandar G Khan, Ahmet Metin, Engin Gozukara, Steffen Emmert, Hanoch Slor, David B Busch, Carl C Baker, John J DiGiovanna, Deborah Tamura, Cornelia S Seitz, Alexei Gratchev, Wen Hao Wu, Kee Yang Chung, Hye Jin Chung, Esther Azizi, Roger Woodgate, Thomas D Schneider and Kenneth H Kraemer

J Invest Dermatol 128: 2055-2068; advance online publication, March 27, 2008; doi:10.1038/jid.2008.48

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TNF- Impairs the S-G2/M Cell Cycle Checkpoint and Cyclobutane Pyrimidine Dimer Repair in Premalignant Skin Cells: Role of the PI3K–Akt Pathway FREE

Annesofie Faurschou, Robert Gniadecki, Damien Calay and Hans Christian Wulf

J Invest Dermatol 128: 2069-2077; advance online publication, February 14, 2008; doi:10.1038/jid.2008.19

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Imiquimod Leads to a Decrease of Human Papillomavirus DNA and to a Sustained Clearance of Anal Intraepithelial Neoplasia in HIV-Infected Men FREE

Alexander Kreuter, Anja Potthoff, Norbert H Brockmeyer, Thilo Gambichler, Markus Stücker, Peter Altmeyer, Jochen Swoboda, Herbert Pfister and Ulrike Wieland for the German Competence Network HIV/AIDS

J Invest Dermatol 128: 2078-2083; advance online publication, February 14, 2008; doi:10.1038/jid.2008.24

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Microtubule-Targeted Drugs Inhibit VEGF Receptor-2 Expression by both Transcriptional and Post-Transcriptional Mechanisms FREE

Markus Meissner, Andreas Pinter, Despina Michailidou, Igor Hrgovic, Natalia Kaprolat, Monika Stein, Wolfgang Holtmeier, Roland Kaufmann and Jens Gille

J Invest Dermatol 128: 2084-2091; advance online publication, March 6, 2008; doi:10.1038/jid.2008.37

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Profibrinolytic Effects of Metalloproteinases during Skin Wound Healing in the Absence of Plasminogen FREE

Kirsty A Green, Kasper Almholt, Michael Ploug, Birgitte Rønø, Francis J Castellino, Morten Johnsen, Thomas H Bugge, John Rømer and Leif R Lund

J Invest Dermatol 128: 2092-2101; advance online publication, March 13, 2008; doi:10.1038/jid.2008.54

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The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment FREE

Héctor G Pálmer, Dolores Martinez, Geert Carmeliet and Fiona M Watt

J Invest Dermatol 128: 2113-2117; advance online publication, March 13, 2008; doi:10.1038/jid.2008.43

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Loss-of-Function Mutations in the Filaggrin Gene Lead to Reduced Level of Natural Moisturizing Factor in the Stratum Corneum FREE

Sanja Kezic, Patrick M J H Kemperman, Ellen S Koster, Cindy M de Jongh, Hok Bing Thio, Linda E Campbell, Alan D Irvine, Irwin W H McLean, Gerwin J Puppels and Peter J Caspers

J Invest Dermatol 128: 2117-2119; advance online publication, February 28, 2008; doi:10.1038/jid.2008.29

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Depletion of Human Peripheral Blood Lymphocytes in CD25+ Cells Allows for the Sensitive In Vitro Screening of Contact Allergens FREE

Marc Vocanson, Magalie Cluzel-Tailhardat, Gaelle Poyet, Magalie Valeyrie, Cyril Chavagnac, Béatrice Levarlet, Pascal Courtellemont, Aurore Rozières, Ana Hennino and Jean-François Nicolas

J Invest Dermatol 128: 2119-2122; advance online publication, February 7, 2008; doi:10.1038/jid.2008.15

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Increased Melanocytic Nevi and Nevus Density in a G-34T CDKN2A/p16 Melanoma-Prone Pedigree FREE

Scott R Florell, Laurence J Meyer, Kenneth M Boucher, Douglas Grossman, Lisa A Cannon-Albright, Ronald M Harris, Wolfram E Samlowski, John J Zone and Sancy A Leachman

J Invest Dermatol 128: 2122-2125; advance online publication, March 13, 2008; doi:10.1038/jid.2008.51

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