Journal of Investigative Dermatology

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Calcineurin Activity and Inhibition in Skin and (Epi)Dermal Cell Cultures

N P M Smit, H H Van Rossum, F P Romijn, K J Sellar, M Breetveld, S Gibbs and J Van Pelt

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Figure 2.

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Calcineurin activity measurements in different fibroblast, keratinocyte, and melanocyte cultures. Cn activity measurements were performed in lysates of fibroblasts (Fb, n=14), keratinocytes (Kc, n=9), and melanocytes (Mc, n=3). Significant differences in Cn activity were observed between fibroblasts and keratinocytes (* P=0.018) and between keratinocytes and melanocytes (** P=0.030). All keratinocyte cultures were maintained in Fei medium.

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