TABLE OF CONTENTS

Volume 128, Issue 6 (June 2008)

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Editorials

JID Welcomes Hypothesis Letters FREE

J Invest Dermatol 128: 1345; doi:10.1038/jid.2008.79

See also: Letter to the Editor by Stenn et al.

Research Snippets FREE

J Invest Dermatol 128: 1348; doi:10.1038/jid.2008.126

Editor's Picks FREE

J Invest Dermatol 128: 1349; doi:10.1038/jid.2008.115

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Journal Club

Catestatin: A New Member of the Cutaneous Defense System FREE

Lucy K Martin, Shasa Hu and Robert S Kirsner

J Invest Dermatol 128: 1350; doi:10.1038/jid.2008.130

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Meeting Report

56th Annual Montagna Symposium on the Biology of Skin: Epidermal T-Cell Interactions—Clinicopathological and Basic Mechanisms FREE

Kevin D Cooper, Richard D Sontheimer, Jan Dutz, Sam T Hwang, Brian J Nickoloff, Shinji Shimada, Molly Kulesz-Martin and Jackie R Bickenbach

J Invest Dermatol 128: 1351-1353; doi:10.1038/jid.2008.99

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Commentaries

Synergistic Signaling from Extracellular Matrix–Growth Factor Complexes FREE

Richard A.F. Clark

J Invest Dermatol 128: 1354-1355; doi:10.1038/jid.2008.75

See also: Original Article by Upton et al.

beta-Papillomavirus Infection and Skin Cancer FREE

Jan Nico Bouwes Bavinck, Elsemieke I Plasmeijer and Mariet C W Feltkamp

J Invest Dermatol 128: 1355-1358; doi:10.1038/jid.2008.123

See also: Original Article by Asgari et al.

Unraveling the Mysteries of IGF-1 Signaling in Melanoma FREE

John T Lee, Patricia Brafford and Meenhard Herlyn

J Invest Dermatol 128: 1358-1360; doi:10.1038/jid.2008.124

See also: Original Article by Hilmi et al.

First-Class Delivery: Getting Growth Factors to Their Destination FREE

Jeffrey M Davidson

J Invest Dermatol 128: 1360-1362; doi:10.1038/jid.2008.128

See also: Original Article by Escámez et al.

Filaggrin Mutations and Allergic Contact Sensitization FREE

Jon M Hanifin

J Invest Dermatol 128: 1362-1364; doi:10.1038/sj.jid.5701253

See also: Original Article by Novak et al.
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Review

Cell Biology

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The Epidermal Growth Factor Receptor System in Skin Repair and Inflammation FREE

Saveria Pastore, Francesca Mascia, Valentina Mariani and Giampiero Girolomoni

J Invest Dermatol 128: 1365-1374; advance online publication, November 29, 2007; doi:10.1038/sj.jid.5701184

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Original Articles

Appendages

Plakophilin-3-Deficient Mice Develop Hair Coat Abnormalities and Are Prone to Cutaneous Inflammation FREE

Tatyana Sklyarova, Stefan Bonné, Petra D'Hooge, Geertrui Denecker, Steven Goossens, Riet De Rycke, Gaetan Borgonie, Michael Bösl, Frans van Roy and Jolanda van Hengel

J Invest Dermatol 128: 1375-1385; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701189

Cell Biology

Cells Isolated from the Epidermis by Hoechst Dye Exclusion, Small Size, and Negative Selection for Hematopoietic Markers Can Generate B Lymphocyte Precursors FREE

Mathew M Stern, Lorraine T Tygrett, Thomas J Waldschmidt and Jackie R Bickenbach

J Invest Dermatol 128: 1386-1396; advance online publication, December 20, 2007; doi:10.1038/sj.jid.5701202

Interaction of Extracellular Matrix Protein 1 with Extracellular Matrix Components: ECM1 Is a Basement Membrane Protein of the Skin FREE

Sandy Sercu, Mei Zhang, Noritaka Oyama, Uwe Hansen, Abdoel E L Ghalbzouri, Gu Jun, Kristof Geentjens, Lurong Zhang and Joseph H Merregaert

J Invest Dermatol 128: 1397-1408; advance online publication, January 17, 2008; doi:10.1038/sj.jid.5701231

Clinical Research

Detection of Human Papillomavirus DNA in Cutaneous Squamous Cell Carcinoma among Immunocompetent Individuals FREE

Maryam M Asgari, Nancy B Kiviat, Cathy W Critchlow, Joshua E Stern, Zsolt B Argenyi, Gregory J Raugi, Daniel Berg, Peter B Odland, Stephen E Hawes and Ethel-Michele de Villiers

J Invest Dermatol 128: 1409-1417; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701227

See also: Commentary by Bavinck et al.

Genetics

Identification of a Genetic Locus for Ichthyosis Vulgaris on Chromosome 10q22.3–q24.2 FREE

Ping Liu, Qingyu Yang, Xu Wang, Aiping Feng, Tao Yang, Rong Yang, Pengyun Wang, Mingxiong Yuang, Mugen Liu, Jing Yu Liu and Qing K Wang

J Invest Dermatol 128: 1418-1422; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701191

Normophosphatemic Familial Tumoral Calcinosis Is Caused by Deleterious Mutations in SAMD9, Encoding a TNF-alpha Responsive Protein FREE

Ilana Chefetz, Danny Ben Amitai, Sarah Browning, Karl Skorecki, Noam Adir, Mark G Thomas, Larissa Kogleck, Orit Topaz, Margarita Indelman, Jouni Uitto, Gabriele Richard, Neil Bradman and Eli Sprecher

J Invest Dermatol 128: 1423-1429; advance online publication, December 20, 2007; doi:10.1038/sj.jid.5701203

Loss-of-Function Mutations in the Filaggrin Gene and Allergic Contact Sensitization to Nickel FREE

Natalija Novak, Hansjörg Baurecht, Torsten Schäfer, Elke Rodriguez, Stefan Wagenpfeil, Norman Klopp, Joachim Heinrich, Heidrun Behrendt, Johannes Ring, Erich Wichmann, Thomas Illig and Stephan Weidinger

J Invest Dermatol 128: 1430-1435; advance online publication, November 29, 2007; doi:10.1038/sj.jid.5701190

See also: Commentary by Hanifin
Specific Filaggrin Mutations Cause Ichthyosis Vulgaris and Are Significantly Associated with Atopic Dermatitis in Japan FREE

Toshifumi Nomura, Masashi Akiyama, Aileen Sandilands, Ikue Nemoto-Hasebe, Kaori Sakai, Akari Nagasaki, Mitsuhito Ota, Hiroo Hata, Alan T Evans, Colin N A Palmer, Hiroshi Shimizu and W H Irwin McLean

J Invest Dermatol 128: 1436-1441; advance online publication, January 17, 2008; doi:10.1038/sj.jid.5701205

A p.C217R Mutation in Fibulin-5 from Cutis Laxa Patients Is Associated with Incomplete Extracellular Matrix Formation in a Skin Equivalent Model FREE

Stephanie Claus, Judith Fischer, Hala Mégarbané, André Mégarbané, Florence Jobard, Romain Debret, Simone Peyrol, Safa Saker, Martine Devillers, Pascal Sommer and Odile Damour

J Invest Dermatol 128: 1442-1450; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701211

Immunology/Infection

The IgE-Reactive Autoantigen Hom s 2 Induces Damage of Respiratory Epithelial Cells and Keratinocytes via Induction of IFN-bold gamma FREE

Irene Mittermann, Renate Reininger, Maya Zimmermann, Katharina Gangl, Jürgen Reisinger, Karl J Aichberger, Elli K Greisenegger, Verena Niederberger, Joachim Seipelt, Barbara Bohle, Tamara Kopp, Cezmi A Akdis, Susanne Spitzauer, Peter Valent and Rudolf Valenta

J Invest Dermatol 128: 1451-1459; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701195

Human Natural Killer T Cells Infiltrate into the Skin at Elicitation Sites of Allergic Contact Dermatitis FREE

Michael D Gober, Rita Fishelevich, Yuming Zhao, Derya Unutmaz and Anthony A Gaspari

J Invest Dermatol 128: 1460-1469; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701199

CD24a Expression Levels Discriminate Langerhans Cells from Dermal Dendritic Cells in Murine Skin and Lymph Nodes FREE

Susanne Stutte, Bettina Jux, Charlotte Esser and Irmgard Förster

J Invest Dermatol 128: 1470-1475; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701228

Keratinocytes/Epidermis

Protein Therapeutics for Junctional Epidermolysis Bullosa: Incorporation of Recombinant beta3 Chain into Laminin 332 in beta3- /- Keratinocytes In Vitro  FREE

Olga Igoucheva, Aislinn Kelly, Jouni Uitto and Vitali Alexeev

J Invest Dermatol 128: 1476-1486; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701197

Lysophospholipid Receptor-Mediated Calcium Signaling in Human Keratinocytes FREE

Karin Lichte, Roberto Rossi, Kerstin Danneberg, Michael ter Braak, Ulrich Kürschner, Karl H Jakobs, Burkhard Kleuser and Dagmar Meyer zu Heringdorf

J Invest Dermatol 128: 1487-1498; advance online publication, January 3, 2008; doi:10.1038/sj.jid.5701207

Melanocytes/Melanoma

IGF1 Promotes Resistance to Apoptosis in Melanoma Cells through an Increased Expression of BCL2, BCL-X(L), and Survivin FREE

Caroline Hilmi, Lionel Larribere, Sandy Giuliano, Karine Bille, Jean-Paul Ortonne, Robert Ballotti and Corine Bertolotto

J Invest Dermatol 128: 1499-1505; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701185

See also: Commentary by Lee et al.
Transcriptional Modulation Using HDACi Depsipeptide Promotes Immune Cell-Mediated Tumor Destruction of Murine B16 Melanoma FREE

Takashi Murakami, Atsuko Sato, Nicole A L Chun, Mayumi Hara, Yuki Naito, Yukiko Kobayashi, Yasuhiko Kano, Mamitaro Ohtsuki, Yusuke Furukawa and Eiji Kobayashi

J Invest Dermatol 128: 1506-1516; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701216

Neurobiology

KRT14 Haploinsufficiency Results in Increased Susceptibility of Keratinocytes to TNF-alpha-Induced Apoptosis and Causes Naegeli–Franceschetti–Jadassohn Syndrome FREE

Jennie Lugassy, John A McGrath, Peter Itin, Revital Shemer, Julian Verbov, Helen R Murphy, Akemi Ishida-Yamamoto, John J DiGiovanna, Dani Bercovich, Nathan Karin, Alon Vitenshtein, Jouni Uitto, Reuven Bergman, Gabriele Richard and Eli Sprecher

J Invest Dermatol 128: 1517-1524; advance online publication, November 29, 2007; doi:10.1038/sj.jid.5701187

The Neuroendocrine Peptide Catestatin Is a Cutaneous Antimicrobial and Induced in the Skin after Injury FREE

Katherine A Radek, Belen Lopez-Garcia, Melanie Hupe, Ingrid R Niesman, Peter M Elias, Laurent Taupenot, Sushil K Mahata, Daniel T O'Connor and Richard L Gallo

J Invest Dermatol 128: 1525-1534; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701225

Wound Healing

Vitronectin: Growth Factor Complexes Hold Potential as a Wound Therapy Approach FREE

Zee Upton, Leila Cuttle, Anthony Noble, Margit Kempf, Gemma Topping, Jos Malda, Yan Xie, Julie Mill, Damien G Harkin, Olena Kravchuk, David I Leavesley and Roy M Kimble

J Invest Dermatol 128: 1535-1544; advance online publication, January 17, 2008; doi:10.1038/sj.jid.5701148

See also: Commentary by Clark
High-Mobility Group Box 1 Protein in Human and Murine Skin: Involvement in Wound Healing FREE

Stefania Straino, Anna Di Carlo, Antonella Mangoni, Roberta De Mori, Liliana Guerra, Riccardo Maurelli, Laura Panacchia, Fabio Di Giacomo, Roberta Palumbo, Cristiana Di Campli, Luigi Uccioli, Paolo Biglioli, Marco E Bianchi, Maurizio C Capogrossi and Antonia Germani

J Invest Dermatol 128: 1545-1553; advance online publication, January 31, 2008; doi:10.1038/sj.jid.5701212

Simplifying the Delivery of Melanocytes and Keratinocytes for the Treatment of Vitiligo Using a Chemically Defined Carrier Dressing FREE

Paula C Eves, Nial A Bullett, David Haddow, Alison J Beck, Christopher Layton, Louise Way, Alex G Shard, David J Gawkrodger and Sheila Mac Neil

J Invest Dermatol 128: 1554-1564; advance online publication, January 17, 2008; doi:10.1038/sj.jid.5701214

Assessment of Optimal Virus-Mediated Growth Factor Gene Delivery for Human Cutaneous Wound Healing Enhancement FREE

María J Escámez, Marta Carretero, Marta García, Lucía Martínez-Santamaría, Isabel Mirones, Blanca Duarte, Almudena Holguín, Eva García, Verónica García, Alvaro Meana, José L Jorcano, Fernando Larcher and Marcela Del Río

J Invest Dermatol 128: 1565-1575; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701217

See also: Commentary by Davidson
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Letters to the Editor

Appendages

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Phylogeny of the Hair Follicle: The Sebogenic Hypothesis FREE

K S Stenn, Y Zheng and S Parimoo

J Invest Dermatol 128: 1576-1578; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701200

Clinical Research

Activity and Safety of Pegylated Liposomal Doxorubicin as First-Line Therapy in the Treatment of Non-Visceral Classic Kaposi's Sarcoma: A Multicenter Study FREE

Giuseppe Di Lorenzo, Alexander Kreuter, Rossella Di Trolio, Attilio Guarini, Carmela Romano, Vincenzo Montesarchio, Norbert H Brockmeyer, Sabino De Placido, Mark Bower and Bruce J Dezube

J Invest Dermatol 128: 1578-1580; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701215

Comment on "Absence of Senescence-Associated beta-Galactosidase Activity in Human Melanocytic Nevi In Vivo" FREE

Vanessa C Gray-Schopfer, Julia K Soo and Dorothy C Bennett

J Invest Dermatol 128: 1581; doi:10.1038/sj.jid.5701220

Clinical Research

Comment on "Absence of Senescence-Associated beta-Galactosidase Activity in Human Melanocytic Nevi In Vivo" FREE

Chrysiis Michaloglou, Maria S Soengas, Wolter J Mooi and Daniel S Peeper

J Invest Dermatol 128: 1582-1583; doi:10.1038/sj.jid.5701221

Response to Gray-Schopfer et al. and Michaloglou et al.  FREE

Murray A Cotter, Scott R Florell, Sancy A Leachman and Douglas Grossman

J Invest Dermatol 128: 1583-1584; doi:10.1038/sj.jid.5701222

Melanocytes/Melanoma

Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, Contribute to Risk of Cutaneous Melanoma FREE

Chunying Li, Kexin Chen, Zhensheng Liu, Li-E Wang, Jeffrey E Gershenwald, Jeffrey E Lee, Victor G Prieto, Madeleine Duvic, Elizabeth A Grimm and Qingyi Wei

J Invest Dermatol 128: 1585-1588; advance online publication, November 29, 2007; doi:10.1038/sj.jid.5701186

Genetics

Polymorphism Patterns in the Promoter Region of the MC1R Gene Are Associated with Development of Freckles and Solar Lentigines FREE

Tomonori Motokawa, Tomomi Kato, Yuki Hashimoto, Hiroyuki Takimoto, Hiroaki Yamamoto and Takayuki Katagiri

J Invest Dermatol 128: 1588-1591; advance online publication, December 13, 2007; doi:10.1038/sj.jid.5701192

Prevalent and Low-Frequency Null Mutations in the Filaggrin Gene Are Associated with Early-Onset and Persistent Atopic Eczema FREE

Sara J Brown, Aileen Sandilands, Yiwei Zhao, Haihui Liao, Caroline L Relton, Simon J Meggitt, Richard C Trembath, Jonathan N W N Barker, Nick J Reynolds, Heather J Cordell and W H Irwin McLean

J Invest Dermatol 128: 1591-1594; advance online publication, December 20, 2007; doi:10.1038/sj.jid.5701206

Immunology/Infection

Filaggrin Expression in Oral, Nasal, and Esophageal Mucosa FREE

Anna De Benedetto, Cary M Qualia, Fuad M Baroody and Lisa A Beck

J Invest Dermatol 128: 1594-1597; advance online publication, January 3, 2008; doi:10.1038/sj.jid.5701208

Photobiology

Adult-Onset Neurological Degeneration in a Patient with Cockayne Syndrome and a Null Mutation in the CSB Gene FREE

Satoru Hashimoto, Tomohiro Suga, Erina Kudo, Hironobu Ihn, Makoto Uchino and Satoshi Tateishi

J Invest Dermatol 128: 1597-1599; advance online publication, January 10, 2008; doi:10.1038/sj.jid.5701210

Vascular Biology

Single-Nucleotide Polymorphisms and Haplotypes in the VEGF Receptor 3 Gene and the Haplotype GC in the VEGFA Gene Are Associated with Psoriasis in Koreans FREE

Joo-Heung Lee, Eun-Young Cho, Jung-Hyun Namkung, Eugene Kim, Sook Kim, Eun-Soon Shin, Jong-Eun Lee and Jun-Mo Yang

J Invest Dermatol 128: 1599-1603; advance online publication, December 20, 2007; doi:10.1038/sj.jid.5701204

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Corrigendum

Corrigendum: Loss-of-Function Mutations in the Filaggrin Gene Lead to Reduced Level of Natural Moisturizing Factor in the Stratum Corneum FREE

J Invest Dermatol 128: 1604; doi:10.1038/jid.2008.105

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Abstracts

Intersociety Liaison Committee Concurrent Session Advances in Dermatology: Medical Dermatology FREE

J Invest Dermatol 128: 1605-1607; doi:10.1038/jid.2008.87

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