Journal of Investigative Dermatology

FIGURE 3

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An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution

Abigail K Langton, Sarah E Herrick and Denis J Headon

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Figure 3.

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Wound reepithelialization in skin lacking HFs undergoes an acute delay followed by completion of repair. (a–h) Hematoxylin- and eosin-stained cross-sections of full thickness incisional wounds made in Edaradd cr/+ (a–d) and Edaradd cr/cr (e–h) tail skin. (a, e) Day 3, (b, f) day 4, (c, g) day 6, (d, h) day 8 post-wounding. Arrows indicate epidermal leading edges. Bar=100 mum. (i) Quantification of wound widths in Edaradd cr/cr and Edaradd cr/+ littermates from 3 to 8 days post-wounding. Error bars show SEM.

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