TABLE OF CONTENTS

Volume 127, Issue 8 (August 2007)

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Editorials

Conflicts of Interest in Dermatology: More than Skin Deep? FREE

Thomas Peter Stossel

J Invest Dermatol 127: 1829-1830; doi:10.1038/sj.jid.5700901

See also: Editorial by Williams

Full Disclosure—Nothing Less Will Do FREE

Hywel C Williams Section Editor

J Invest Dermatol 127: 1831-1833; doi:10.1038/sj.jid.5700931

See also: Editorial by Stossel

Research Snippets FREE

J Invest Dermatol 127: 1836; doi:10.1038/sj.jid.5701014

Editors' Picks FREE

J Invest Dermatol 127: 1837; doi:10.1038/sj.jid.5700984

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Meeting Report

Meeting Report of Immunology and Skin Disease: New Perspectives FREE

Rachael A Clark and Robert C Fuhlbrigge

J Invest Dermatol 127: 1838-1841; doi:10.1038/sj.jid.5700886

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In Memoriam

Clayton E. Wheeler Jr. 1917–2007: The Early Years as Teacher, Clinician, and Scientist FREE

Peyton E Weary

J Invest Dermatol 127: 1842; doi:10.1038/sj.jid.5700982

Clayton E. Wheeler Jr.: The Early Years at the University of North Carolina FREE

Al Briggaman

J Invest Dermatol 127: 1842-1844; doi:10.1038/sj.jid.5700976

Remembering Clayton E. Wheeler Jr. FREE

Luis A Diaz

J Invest Dermatol 127: 1844-1845; doi:10.1038/sj.jid.5700985

Clayton E. Wheeler Jr.: Learning at the Master's Knee FREE

William A Burke

J Invest Dermatol 127: 1845-1846; doi:10.1038/sj.jid.5700887

Clayton E. Wheeler Jr., Teacher: Diagnostic Skills and Bedside Manner FREE

Fred Ghali

J Invest Dermatol 127: 1846-1847; doi:10.1038/sj.jid.5700979

Becoming an Academic Clinician: Learning from Clayton E. Wheeler Jr. FREE

Joseph L Jorizzo

J Invest Dermatol 127: 1847-1848; doi:10.1038/sj.jid.5700980

Lessons Learned from Clayton E. Wheeler Jr. FREE

Dean S Morrell

J Invest Dermatol 127: 1848-1849; doi:10.1038/sj.jid.5700981

Clayton E. Wheeler Jr.: An Inspiring Teacher FREE

Boni E Elewski

J Invest Dermatol 127: 1850; doi:10.1038/sj.jid.5700978

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Commentaries

The Power and Limitations of Pharmacogenetic Epidemiology FREE

Kate Lapane and Martin A Weinstock

J Invest Dermatol 127: 1851-1852; doi:10.1038/sj.jid.5700854

See also: Original Article by Patel et al.

Inflammasome Activation in Delayed-Type Hypersensitivity Reactions FREE

Amir S Yazdi, Kamran Ghoreschi and Martin Röcken

J Invest Dermatol 127: 1853-1855; doi:10.1038/sj.jid.5700815

See also: Original Article by Watanabe et al.

TRP-ing Up Melanophores: TRPM7, Melanin Synthesis, and Pigment Cell Survival FREE

Aurel O Iuga and Ethan A Lerner

J Invest Dermatol 127: 1855-1856; doi:10.1038/sj.jid.5700773

See also: Original Article by McNeill et al.

The Pruritus Receptor Unit: A Target for Novel Therapies FREE

Gil Yosipovitch

J Invest Dermatol 127: 1857-1859; doi:10.1038/sj.jid.5700818

See also: Original Article by Andoh et al.
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Original ArticlesOriginal Articles

Clinical Research

Polymorphisms in Folate, Pyrimidine, and Purine Metabolism Are Associated with Efficacy and Toxicity of Methotrexate in Psoriasis FREE

Emanuela Campalani, Monica Arenas, Anthony M Marinaki, Cathryn M Lewis, Jonathan N W N Barker and Catherine H Smith

J Invest Dermatol 127: 1860-1867; advance online publication, April 5, 2007; doi:10.1038/sj.jid.5700808

Gene–Drug Interaction at the Glucocorticoid Receptor Increases Risk of Squamous Cell Skin Cancer FREE

Anita S Patel, Margaret R Karagas, Ann E Perry, Steven K Spencer and Heather H Nelson

J Invest Dermatol 127: 1868-1870; advance online publication, March 29, 2007; doi:10.1038/sj.jid.5700798

See also: Commentary by Lapane & Weinstock
Improving Sun-Protection Behavior among Children: Results of a Cluster-Randomized Trial in Italian Elementary Schools. The "SoleSi SoleNo-GISED" Project FREE

Luigi Naldi, Liliane Chatenoud, Paola Bertuccio, Cornelia Zinetti, Anna Di Landro, Lorenza Scotti and Carlo La Vecchia the Oncology Cooperative Group of the Italian Group for Epidemiologic Research in Dermatology (GISED)

J Invest Dermatol 127: 1871-1877; advance online publication, April 26, 2007; doi:10.1038/sj.jid.5700835

Filaggrin Null Alleles Are Not Associated with Psoriasis FREE

Yiwei Zhao, Ana Terron-Kwiatkowski, Haihui Liao, Simon P Lee, Michael H Allen, Peter R Hull, Linda E Campbell, Richard C Trembath, Francesca Capon, Christopher E M Griffiths, David Burden, Ross McManus, Rosalind Hughes, Brian Kirby, Sarah F Rogers, Oliver Fitzgerald, David Kane, Jonathan N W N Barker, Colin N A Palmer, Alan D Irvine and W H Irwin McLean

J Invest Dermatol 127: 1878-1882; advance online publication, April 5, 2007; doi:10.1038/sj.jid.5700817

Genetics

Spectrum of FGFR3 Mutations in Multiple Intraindividual Seborrheic Keratoses FREE

Christian Hafner, Arndt Hartmann, Francisco X Real, Ferdinand Hofstaedter, Michael Landthaler and Thomas Vogt

J Invest Dermatol 127: 1883-1885; advance online publication, March 29, 2007; doi:10.1038/sj.jid.5700804

TNF-alpha Gene Promoter -238G>A and -308G>A Polymorphisms Alter Risk of Psoriasis Vulgaris: A Meta-Analysis FREE

Chunying Li, Gang Wang, Ying Gao, Ling Liu and Tianwen Gao

J Invest Dermatol 127: 1886-1892; advance online publication, April 19, 2007; doi:10.1038/sj.jid.5700822

A Mouse Mutation in the 12R-Lipoxygenase, Alox12b, Disrupts Formation of the Epidermal Permeability Barrier FREE

Jennifer L Moran, Haiyan Qiu, Annick Turbe-Doan, Yujuan Yun, William E Boeglin, Alan R Brash and David R Beier

J Invest Dermatol 127: 1893-1897; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700825

Immunology/Infection

Differential Expression of TRAF1 Aids in the Distinction of Cutaneous CD30-Positive Lymphoproliferations FREE

Chalid Assaf, Burkhard Hirsch, Florian Wagner, Lothar Lucka, Maria Grünbaum, Sylke Gellrich, Ansgar Lukowsky, Wolfram Sterry, Harald Stein and Horst Dürkop

J Invest Dermatol 127: 1898-1904; advance online publication, March 29, 2007; doi:10.1038/sj.jid.5700800

Absence of Cutaneous TNFalpha-Producing CD4+ T Cells and TNFalpha may Allow for Fibrosis Rather than Epithelial Cytotoxicity in Murine Sclerodermatous Graft-Versus-Host Disease, a Model for Human Scleroderma FREE

David Askew, Lixin Zhou, Cayun Wu, Guofen Chen and Anita C Gilliam

J Invest Dermatol 127: 1905-1914; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700813

Early Inflammatory Changes in the "Perilesional Skin" of Psoriatic Plaques: Is there Interaction between Dendritic Cells and Keratinocytes? FREE

Mayumi Komine, Masaru Karakawa, Tomonori Takekoshi, Naoki Sakurai, Yosaku Minatani, Hiroshi Mitsui, Yayoi Tada, Hidehisa Saeki, Akihiko Asahina and Kunihiko Tamaki

J Invest Dermatol 127: 1915-1922; advance online publication, April 19, 2007; doi:10.1038/sj.jid.5700799

Smad3 Signal Transducer Regulates Skin Inflammation and Specific IgE Response in Murine Model of Atopic Dermatitis FREE

Minna Anthoni, Guoying Wang, Chuxia Deng, Henrik J Wolff, Antti I Lauerma and Harri T Alenius

J Invest Dermatol 127: 1923-1929; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700809

EC-SOD Suppresses Contact Hypersensitivity in Mouse Skin by Impairing Langerhans Cell Migration FREE

Kwangmin Na, Kyoung-Eun Kim, Sang-Tae Park and Tae-Yoon Kim

J Invest Dermatol 127: 1930-1937; advance online publication, March 29, 2007; doi:10.1038/sj.jid.5700802

Type I IL-1 Receptor Mediates IL-1 and Intracellular IL-1 Receptor Antagonist Effects in Skin Inflammation FREE

Gaby Palmer, Dominique Talabot-Ayer, Gürkan Kaya and Cem Gabay

J Invest Dermatol 127: 1938-1946; advance online publication, May 3, 2007; doi:10.1038/sj.jid.5700803

Serotonin Activates Human Monocytes and Prevents Apoptosis FREE

Fujiko Soga, Norito Katoh, Tomoko Inoue and Saburo Kishimoto

J Invest Dermatol 127: 1947-1955; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700824

Activation of the IL-1beta-Processing Inflammasome Is Involved in Contact Hypersensitivity FREE

Hideki Watanabe, Olivier Gaide, Virginie Pétrilli, Fabio Martinon, Emmanuel Contassot, Stéphanie Roques, Jean A Kummer, Jürg Tschopp and Lars E French

J Invest Dermatol 127: 1956-1963; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700819

See also: Commentary by Yazdi et al.
The 130-kDa Glycoform of CD43 Functions as an E-Selectin Ligand for Activated Th1 Cells In Vitro and in Delayed-Type Hypersensitivity Reactions In Vivo  FREE

Pilar Alcaide, Sandra L King, Charles J Dimitroff, Yaw-Chyn Lim, Robert C Fuhlbrigge and Francis W Luscinskas

J Invest Dermatol 127: 1964-1972; advance online publication, March 29, 2007; doi:10.1038/sj.jid.5700805

Genetics

Involucrin Expression Is Decreased in Hailey–Hailey Keratinocytes Owing to Increased Involucrin mRNA Degradation FREE

Karin M Aberg, Emoke Racz, Martin J Behne and Theodora M Mauro

J Invest Dermatol 127: 1973-1979; advance online publication, March 29, 2007; doi:10.1038/sj.jid.5700785

Keratinocytes/Epidermis

DeltaNp63alpha Promotes Apoptosis of Human Epidermal Keratinocytes FREE

Ling Zhu, Ellen A Rorke and Richard L Eckert

J Invest Dermatol 127: 1980-1991; advance online publication, March 29, 2007; doi:10.1038/sj.jid.5700797

Low Concentrations of Curcumin Induce Growth Arrest and Apoptosis in Skin Keratinocytes Only in Combination with UVA or Visible Light FREE

Jadranka Dujic, Stefan Kippenberger, Stephanie Hoffmann, Ana Ramirez-Bosca, Jaime Miquel, Joquin Diaz-Alperi, Jürgen Bereiter-Hahn, Roland Kaufmann and August Bernd

J Invest Dermatol 127: 1992-2000; advance online publication, April 5, 2007; doi:10.1038/sj.jid.5700801

HaCaT Keratinocytes Overexpressing the S100 Proteins S100A8 and S100A9 Show Increased NADPH Oxidase and NF-kappaB Activities FREE

Malgorzata Benedyk, Claudia Sopalla, Wolfgang Nacken, Günther Bode, Harut Melkonyan, Botond Banfi and Claus Kerkhoff

J Invest Dermatol 127: 2001-2011; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700820

Mitogen- and Stress-Activated Protein Kinase 2 and Cyclic AMP Response Element Binding Protein are Activated in Lesional Psoriatic Epidermis FREE

Anne T Funding, Claus Johansen, Knud Kragballe and Lars Iversen

J Invest Dermatol 127: 2012-2019; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700821

Melanocytes/Melanoma

Cell Death of Melanophores in Zebrafish trpm7 Mutant Embryos Depends on Melanin Synthesis FREE

Matthew S McNeill, Jennifer Paulsen, Gregory Bonde, Erin Burnight, Mei-Yu Hsu and Robert A Cornell

J Invest Dermatol 127: 2020-2030; advance online publication, February 8, 2007; doi:10.1038/sj.jid.5700710

See also: Commentary by Iuga & Lerner
Targeting Tumor-Associated Macrophages and Inhibition of MCP-1 Reduce Angiogenesis and Tumor Growth in a Human Melanoma Xenograft FREE

Silvina Gazzaniga, Alicia I Bravo, Angelo Guglielmotti, Nico van Rooijen, Fabricio Maschi, Annunciata Vecchi, Alberto Mantovani, José Mordoh and Rosa Wainstok

J Invest Dermatol 127: 2031-2041; advance online publication, April 26, 2007; doi:10.1038/sj.jid.5700827

Neurobiology

Thromboxane A2 Induces Itch-Associated Responses through TP Receptors in the Skin in Mice FREE

Tsugunobu Andoh, Yumi Nishikawa, Tomomi Yamaguchi-Miyamoto, Hiroshi Nojima, Shu Narumiya and Yasushi Kuraishi

J Invest Dermatol 127: 2042-2047; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700810

See also: Commentary by Yosipovitch

Photobiology

Helium–Neon Laser Irradiation Stimulates Cell Proliferation through Photostimulatory Effects in Mitochondria FREE

Wan-Ping Hu, Jeh-Jeng Wang, Chia-Li Yu, Cheng-Che E Lan, Gow-Shing Chen and Hsin-Su Yu

J Invest Dermatol 127: 2048-2057; advance online publication, April 19, 2007; doi:10.1038/sj.jid.5700826

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Letters to the Editor

Loss of Heterozygosity Studies on Chromosome 12q in Disseminated Superficial Actinic Porokeratosis: Lessons to be Learned FREE

Jorge Frank, Michel van Geel and Maurice A M van Steensel

J Invest Dermatol 127: 2058-2059; advance online publication, July 5, 2007; doi:10.1038/sj.jid.5700783

Response to Loss of Heterozygosity Studies on Chromosome 12q in Disseminated Superficial Actinic Porokeratosis: Lessons to be Learned FREE

Zhenghua Zhang

J Invest Dermatol 127: 2059-2060; advance online publication, July 5, 2007; doi:10.1038/sj.jid.5700784

Editor's Note FREE

Lowell A Goldsmith Editor

J Invest Dermatol 127: 2060; advance online publication, July 5, 2007; doi:10.1038/sj.jid.5700955

A Novel Mutation in K6b in Pachyonychia Congenita Type 2 FREE

Vishakha M Sharma and Sarah L Stein

J Invest Dermatol 127: 2060-2062; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700814

P75 Plays a Key Role in the Induction of the Sprouting of Sensory Nerve Fibers in Inflamed Skin FREE

Manabu Taniguchi, Shinsuke Matsuzaki and Masaya Tohyama

J Invest Dermatol 127: 2062-2065; advance online publication, April 12, 2007; doi:10.1038/sj.jid.5700806

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