Commentary

Journal of Investigative Dermatology (2007) 127, 2710–2712. doi:10.1038/sj.jid.5701072

Differentiation of Postembryonic Skin Endothelial Cells

Marvin Karasek1

1Department of Dermatology, Stanford University, Stanford, California, USA

Correspondence: Dr Marvin Karasek, Department of Dermatology, Stanford University, 269 Campus Drive, CCSR-2, Room 2155, Stanford, California 94305-5168, USA. E-mail: marvek@stanford.edu

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Abstract

Specific cell markers for selective isolation and growth of cells from the lymphatic and vascular systems have increased our understanding of the structure–function relationships of both systems. Using these markers, a subset of blood vessel endothelial cells (BECs) with the properties of lymphatic endothelial cells (LECs) has been identified in psoriasis and eczema. The differentiation potential of BECs and LECs in vivo and in vitro is reviewed.

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