Journal of Investigative Dermatology

TABLE 2

FROM:

Cutaneous Human Papillomaviruses Persist on Healthy Skin

Kristina Hazard, Anna Karlsson, Kristin Andersson, Henrik Ekberg, Joakim Dillner and Ola Forslund

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Table 2. Multivariate analysis of parameters affecting a persistent infection of any HPV type

  Subjects with persistence/ total (%) Crude OR (95% CI) Adjusted 1 OR (95% CI)
All subjects 19/44 (43)  
 Healthy14/29 (48.3)1.0 (referent)1.0 (referent)
 RTR5/15 (33.3)0.54 (0.12–2.30)0.84 (0.12–5.74)
    
Sex    
 Female13/24 (54.2)1.0 (referent)1.0 (referent)
 Male6/20 (30.0)0.37 (0.09–1.48)0.23 (0.03–1.16)
    
Age (years)    
 <445/14 (35.7)1.0 (referent)1.0 (referent)
 45–546/15 (40.0)1.19 (0.21–7.03)0.56 (0.04–5.53)
 >558/15 (53.3)2.01 (0.37–11.86)0.94 (0.05–17.9)
    
Warts at any site    
 No15/33 (45.5)1.0 (referent)1.0 (referent)
 Yes4/11 (36.4)0.69 (0.12–3.37)0.79 (0.09–6.97)
    
Previous skin cancer    
 No18/42 (42.9)1.0 (referent)1.0 (referent)
 Yes1/2 (50.0)1.33 (0.02–109)2.98 (0.009–1,015)
    
Any previous cancer    
 No17/39 (43.6)1.0 (referent)1.0 (referent)
 Yes2/5 (40.0)0.87 (0.06–8.47)0.31 (0.004–8.9)
    
Any allergy    
 No14/30 (46.7)1.0 (referent)1.0 (referent)
 Yes5/14 (35.7)0.64 (0.13–2.77)0.42 (0.05–2.84)
    
Eczema    
 No14/35 (40.0)1.0 (referent)1.0 (referent)
 Yes5/9 (55.6)1.85 (0.33–11.1)2.43 (0.35–20.3)
    
Genus of HPV    
 gamma 2/12 (16.7)1.0 (referent)1.0 (referent)
 beta 12/20 (60.0)7.02 (1.08–82.7)5.94 (0.64–105)
 gamma+beta 5/12 (41.7)3.38 (0.40–45.4)4.37 (0.33–97.5)

 CI, confidence interval; HPV, human papillomavirus; OR, odds ratio; RTR, renal transplant recipient.

 Only patients positive for HPV in the first sample were included in the analysis. Questions answered at collection of the first sample.

1 Adjusted for all parameters in the table.

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