TABLE OF CONTENTS

Volume 126, Issue 7 (July 2006)

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Editorials

Picking Your Peers FREE

Lowell A Goldsmith Editor, Elizabeth N Blalock Managing Editor, Heather Bobkova Editorial Assistant and Russell P Hall III Deputy Editor

J Invest Dermatol 126: 1429-1430; doi:10.1038/sj.jid.5700387

Research Snippets FREE

J Invest Dermatol 126: 1432; doi:10.1038/sj.jid.5700446

Editors' Picks FREE

J Invest Dermatol 126: 1433; doi:10.1038/sj.jid.5700426

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Meeting Report

Obstacles to Translation Conference FREE

Ervin H Epstein Jr, Barbara A Gilchrest and Leonard M Milstone

J Invest Dermatol 126: 1434-1437; doi:10.1038/sj.jid.5700420

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Commentaries

Assessing the Impact of Psoriasis and the Relevance of Qualitative Research FREE

Ray Jobling and Luigi Naldi

J Invest Dermatol 126: 1438-1440; doi:10.1038/sj.jid.5700223

See also: Original Article by Unaeze et al.

Pseudoxanthoma Elasticum: a Metabolic Disease? FREE

Qiujie Jiang and Jouni Uitto

J Invest Dermatol 126: 1440-1441; doi:10.1038/sj.jid.5700267

See also: Original Article by Le Saux et al.

S100A7 (Psoriasin): a Story of Mice and Men FREE

Richard L Eckert and Kathleen C Lee

J Invest Dermatol 126: 1442-1444; doi:10.1038/sj.jid.5700265

See also: Original Article by Wolf et al.

HLA-Independent Antibacterial Host Response toward Th1 Immunity Mediated by IL-12: a New Concept for the Pathogenesis of Adamantiades–Behçet's Disease FREE

Christos C Zouboulis

J Invest Dermatol 126: 1444-1447; doi:10.1038/sj.jid.5700281

See also: Original Article by Yanagihori et al.

A New Wrinkle on Topical Vitamin E and Photo-inflammation: Mechanistic Studies of a Hydrophilic bold gamma-Tocopherol Derivative Compared with alpha-Tocopherol FREE

Raymond L Konger

J Invest Dermatol 126: 1447-1449; doi:10.1038/sj.jid.5700308

See also: Original Article by Yoshida et al.
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Perspectives

Keratinocytes/Epidermis

Interfollicular Epidermal Stem Cells: Identification, Challenges, Potential FREE

Pritinder Kaur

J Invest Dermatol 126: 1450-1458; doi:10.1038/sj.jid.5700184

Epithelial Stem Cells: A Folliculocentric View FREE

George Cotsarelis

J Invest Dermatol 126: 1459-1468; doi:10.1038/sj.jid.5700376

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Original Articles

Cell Biology

Defining the Regulatory Elements in the Proximal Promoter of DeltaNp63 in Keratinocytes: Potential Roles for Sp1/Sp3, NF-Y, and p63 FREE

Rose-Anne Romano, Barbara Birkaya and Satrajit Sinha

J Invest Dermatol 126: 1469-1479; advance online publication, April 27, 2006; doi:10.1038/sj.jid.5700297

Clinical Research

Impact of Psoriasis on Health-Related Quality of Life Decreases Over Time: An 11-Year Prospective Study FREE

Jane Unaeze, Tamar Nijsten, Amy Murphy, Caitlin Ravichandran and Robert S Stern

J Invest Dermatol 126: 1480-1489; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700229

See also: Commentary by Jobling & Naldi
The Epidemiology of Nevi and Signs of Skin Aging in the Adult General Population: Results of the KORA-Survey 2000 FREE

Torsten Schäfer, Jessica Merkl, Eckart Klemm, Heinz-Erich Wichmann and Johannes Ring the KORA study group

J Invest Dermatol 126: 1490-1496; advance online publication, April 27, 2006; doi:10.1038/sj.jid.5700269

Genetics

Serum Factors from Pseudoxanthoma Elasticum Patients Alter Elastic Fiber Formation In Vitro  FREE

Olivier Le Saux, Severa Bunda, Christopher M VanWart, Vanessa Douet, Laurence Got, Ludovic Martin and Aleksander Hinek

J Invest Dermatol 126: 1497-1505; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700201

See also: Commentary by Jiang & Uitto
Homozygous Missense Mutation in Fibulin-5 in an Iranian Autosomal Recessive Cutis Laxa Pedigree and Associated Haplotype FREE

Elahe Elahi, Reza Kalhor, Setareh S Banihosseini, Noorossadat Torabi, Hamid Pour-Jafari, Massoud Houshmand, Seyed S H Amini, Ahmad Ramezani and Bart Loeys

J Invest Dermatol 126: 1506-1509; advance online publication, May 11, 2006; doi:10.1038/sj.jid.5700247

MC1R and PTCH Gene Polymorphism in French Patients with Basal Cell Carcinomas FREE

Muriel Liboutet, Marc Portela, Gisèle Delestaing, Catherine Vilmer, Nicolas Dupin, Isabelle Gorin, Philippe Saiag, Céleste Lebbé, Delphine Kerob, Louis Dubertret, Bernard Grandchamp, Nicole Basset-Seguin and Nadem Soufir

J Invest Dermatol 126: 1510-1517; advance online publication, April 27, 2006; doi:10.1038/sj.jid.5700263

Compound Heterozygous Mutations Including a De Novo Missense Mutation in ABCA12 Led to a Case of Harlequin Ichthyosis with Moderate Clinical Severity FREE

Masashi Akiyama, Kaori Sakai, Yoriko Sugiyama-Nakagiri, Yasuko Yamanaka, James R McMillan, Daisuke Sawamura, Hironori Niizeki, Sachiko Miyagawa and Hiroshi Shimizu

J Invest Dermatol 126: 1518-1523; advance online publication, May 4, 2006; doi:10.1038/sj.jid.5700295

Immunology/Infection

Induction of Regulatory T Cells by Leflunomide in a Murine Model of Contact Allergen Sensitivity FREE

Benno Weigmann, Elizabeth R Jarman, Stephan Sudowe, Matthias Bros, Jürgen Knop and Angelika B Reske-Kunz

J Invest Dermatol 126: 1524-1533; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700228

Role of IL-12B Promoter Polymorphism in Adamantiades–Behcet's Disease Susceptibility: An Involvement of Th1 Immunoreactivity against Streptococcus Sanguinis Antigen FREE

Hirokatsu Yanagihori, Noritaka Oyama, Koichiro Nakamura, Nobuhisa Mizuki, Keiji Oguma and Fumio Kaneko

J Invest Dermatol 126: 1534-1540; advance online publication, March 2, 2006; doi:10.1038/sj.jid.5700203

See also: Commentary by Zouboulis
Multiphoton High-Resolution 3D Imaging of Langerhans Cells and Keratinocytes in the Mouse Skin Model Adopted for Epidermal Powdered Immunization FREE

William J Mulholland, Edward A H Arbuthnott, Brian J Bellhouse, J Frederick Cornhill, Jonathan M Austyn, Mark A F Kendall, Zhanfeng Cui and Uday K Tirlapur

J Invest Dermatol 126: 1541-1548; advance online publication, April 27, 2006; doi:10.1038/sj.jid.5700290

Identification and Characterization of Endogenous Langerin Ligands in Murine Extracellular Matrix FREE

Yayoi Tada, Elisabeth Riedl, Mark S Lowenthal, Lance A Liotta, David M Briner, Erika C Crouch and Mark C Udey

J Invest Dermatol 126: 1549-1558; advance online publication, March 23, 2006; doi:10.1038/sj.jid.5700283

A Chronic Contact Eczema Impedes Migration of Antigen-Presenting Cells in Alopecia Areata FREE

Pooja Gupta, Pia Freyschmidt-Paul, Mario Vitacolonna, Sabine Kiessling, Susanne Hummel, Dagmar Hildebrand, Rachid Marhaba and Margot Zöller

J Invest Dermatol 126: 1559-1573; advance online publication, May 4, 2006; doi:10.1038/sj.jid.5700328

See also: Editorial by
SOCS1-Negative Feedback of STAT1 Activation Is a Key Pathway in the dsRNA-Induced Innate Immune Response of Human Keratinocytes FREE

Xiuju Dai, Koji Sayama, Kenshi Yamasaki, Mikiko Tohyama, Yuji Shirakata, Yasushi Hanakawa, Sho Tokumaru, Yoko Yahata, Lujun Yang, Akihiko Yoshimura and Koji Hashimoto

J Invest Dermatol 126: 1574-1581; advance online publication, April 20, 2006; doi:10.1038/sj.jid.5700294

Distinct Roles for IL-1 Receptor Type I Signaling in Early Versus Established Leishmania major Infections FREE

Susanna Lopez Kostka, Jürgen Knop, Abdo Konur, Mark C Udey and Esther von Stebut

J Invest Dermatol 126: 1582-1589; advance online publication, April 27, 2006; doi:10.1038/sj.jid.5700309

See also: Editorial by
Prominent Production of IL-20 by CD68+/CD11c+ Myeloid-Derived Cells in Psoriasis: Gene Regulation and Cellular Effects FREE

Frank Wang, Edmund Lee, Michelle A Lowes, Asifa S Haider, Judilyn Fuentes-Duculan, Maria Veronica Abello, Francesca Chamian, Irma Cardinale and James G Krueger

J Invest Dermatol 126: 1590-1599; advance online publication, April 27, 2006; doi:10.1038/sj.jid.5700310

See also: Editorial by

Keratinocytes/Epidermis

The Mouse S100A15 Ortholog Parallels Genomic Organization, Structure, Gene Expression, and Protein-Processing Pattern of the Human S100A7/A15 Subfamily During Epidermal Maturation FREE

Ronald Wolf, Christopher J Voscopoulos, Peter C FitzGerald, Paul Goldsmith, Christophe Cataisson, Michele Gunsior, Markus Walz, Thomas Ruzicka and Stuart H Yuspa

J Invest Dermatol 126: 1600-1608; advance online publication, March 9, 2006; doi:10.1038/sj.jid.5700210

See also: Commentary by Eckert & Lee
Serine Protease Activity and Residual LEKTI Expression Determine Phenotype in Netherton Syndrome FREE

Jean-Pierre Hachem, Fredrik Wagberg, Matthias Schmuth, Debra Crumrine, Willy Lissens, Arumugam Jayakumar, Evi Houben, Theodora M Mauro, Göran Leonardsson, Maria Brattsand, Torbjorn Egelrud, Diane Roseeuw, Gary L Clayman, Kenneth R Feingold, Mary L Williams and Peter M Elias

J Invest Dermatol 126: 1609-1621; advance online publication, April 6, 2006; doi:10.1038/sj.jid.5700288

See also: Original Article by Descargues et al.
Corneodesmosomal Cadherins Are Preferential Targets of Stratum Corneum Trypsin- and Chymotrypsin-like Hyperactivity in Netherton Syndrome FREE

Pascal Descargues, Céline Deraison, Catherine Prost, Sylvie Fraitag, Juliette Mazereeuw-Hautier, Marina D'Alessio, Akemi Ishida-Yamamoto, Christine Bodemer, Giovanna Zambruno and Alain Hovnanian

J Invest Dermatol 126: 1622-1632; advance online publication, April 20, 2006; doi:10.1038/sj.jid.5700284

See also: Original Article by Hachem et al.

Photobiology

Topical Application of a Novel, Hydrophilic bold italic gamma-Tocopherol Derivative Reduces Photo-Inflammation in Mice Skin FREE

Emiko Yoshida, Tatsuya Watanabe, Jiro Takata, Akihiko Yamazaki, Yoshiharu Karube and Shizuko Kobayashi

J Invest Dermatol 126: 1633-1640; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700236

See also: Commentary by Konger

Tumor Biology

The Selective Protein Kinase C beta Inhibitor Enzastaurin Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines through the AKT Pathway FREE

Christiane Querfeld, Mujahid A Rizvi, Timothy M Kuzel, Joan Guitart, Alfred Rademaker, Simran S Sabharwal, Nancy L Krett and Steven T Rosen

J Invest Dermatol 126: 1641-1647; advance online publication, April 27, 2006; doi:10.1038/sj.jid.5700322

See also: Editorial by
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Letters to the Editor

Seasonal and Latitudinal Impact of Polymorphic Light Eruption on Quality of Life FREE

Tsui C Ling, Helen L Richards, Artiena S Janssens, Lina Anastassopoulou, Christina Antoniou, Francois Aubin, Thomas L Diepgen, Rosemary Fazakerley, Frank R de Gruijl, Christer T Jansen, Stan Pavel, Andrew Smedley, Alexander J Stratigos, Ann R Webb, Neil K Gibbs and Lesley E Rhodes

J Invest Dermatol 126: 1648-1651; advance online publication, April 20, 2006; doi:10.1038/sj.jid.5700306

See also: Editorial by

Early Death from Cardiomyopathy in a Family with Autosomal Dominant Striate Palmoplantar Keratoderma and Woolly Hair Associated with a Novel Insertion Mutation in Desmoplakin FREE

Elizabeth E Norgett, Tom W Lucke, Bill Bowers, Colin S Munro, Irene M Leigh and David P Kelsell

J Invest Dermatol 126: 1651-1654; advance online publication, April 20, 2006; doi:10.1038/sj.jid.5700291

Epidermolysis Bullosa Simplex with Mottled Pigmentation Resulting from a Recurrent Mutation in KRT14 FREE

Avikam Harel, Reuven Bergman, Margarita Indelman and Eli Sprecher

J Invest Dermatol 126: 1654-1657; advance online publication, April 6, 2006; doi:10.1038/sj.jid.5700296

The A148T Variant of the CDKN2A Gene Is Not Associated with Melanoma Risk in the French and Italian Populations FREE

Tania Spica, Marc Portela, Bénédicte Gérard, Federica Formicone, Vincent Descamps, Béatrice Crickx, Laurence Ollivaud, Alain Archimbaud, Nicolas Dupin, Pierre Wolkenstein, Dominique Vitoux, Céleste Lebbe, Philippe Saiag, Nicole Basset-Seguin, Maria Concetta Fargnoli, Bernard Grandchamp, Ketty Peris, Nadem Soufir and and MELAN-COHORT

J Invest Dermatol 126: 1657-1660; advance online publication, April 13, 2006; doi:10.1038/sj.jid.5700293

PI3-Kinase Subunits Are Infrequent Somatic Targets in Melanoma FREE

John A Curtin, Mitchell S Stark, Daniel Pinkel, Nicholas K Hayward and Boris C Bastian

J Invest Dermatol 126: 1660-1663; advance online publication, April 13, 2006; doi:10.1038/sj.jid.5700311

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Abstracts

Abstracts from the Weill Cornell Symposium on the Science of Dermatology: Stress and the Sun FREE

J Invest Dermatol 126: 1665-1681; doi:10.1038/sj.jid.5700423

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Corrigenda

Abstracts of the 67th Annual Meeting of the Society for Investigative Dermatology FREE

J Invest Dermatol 126: 1682; doi:10.1038/sj.jid.5700440

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