TABLE OF CONTENTS

Volume 126, Issue 6 (June 2006)

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Editorials

Errors in the Lab and in Publications FREE

Lowell A Goldsmith Editor, Russell P Hall III Deputy Editor and Bahjat Qaqish Editor for Epidemiology and Statistics

J Invest Dermatol 126: 1195-1196; doi:10.1038/sj.jid.5700279

Research Snippets FREE

J Invest Dermatol 126: 1198; doi:10.1038/sj.jid.5700378

Editors' Picks FREE

J Invest Dermatol 126: 1199; doi:10.1038/sj.jid.5700358

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Commentaries

Breaking the (Un)Sound Barrier: Filaggrin Is a Major Gene for Atopic Dermatitis FREE

Alan D Irvine and W H Irwin McLean

J Invest Dermatol 126: 1200-1202; doi:10.1038/sj.jid.5700365

See also: Original Article by Gao et al.

Epidermal Differentiation Complex Yields a Secret: Mutations in the Cornification Protein Filaggrin Underlie Ichthyosis Vulgaris FREE

Julia A Segre

J Invest Dermatol 126: 1202-1204; doi:10.1038/sj.jid.5700367

See also: Commentary by Irvine & McLean

PSORS1: Linking Genetics and Immunology FREE

James T Elder

J Invest Dermatol 126: 1205-1206; doi:10.1038/sj.jid.5700357

Cutaneous Microdialysis: Is it Worth the Sweat? FREE

Chris D Anderson

J Invest Dermatol 126: 1207-1209; doi:10.1038/sj.jid.5700221

See also: Original Article by Morgan et al.

The Skin as a Site of Initiation of Systemic Autoimmune Disease: New Opportunities for Treatment FREE

Jan P Dutz

J Invest Dermatol 126: 1209-1212; doi:10.1038/sj.jid.5700238

See also: Original Article by Loser et al.

"Bak (and Bax) to the Future" — of Primary Melanoma Prognosis? FREE

Martin Leverkus and Harald Gollnick

J Invest Dermatol 126: 1212-1214; doi:10.1038/sj.jid.5700239

See also: Original Article by Fecker et al.

Genomic Instability and Tumor Stem Cells FREE

James M Grichnik

J Invest Dermatol 126: 1214-1216; doi:10.1038/sj.jid.5700240

See also: Original Article by Wang et al.

More than One Gene Involved in Monilethrix: Intracellular but also Extracellular Players FREE

Jurgen Schweizer

J Invest Dermatol 126: 1216-1219; doi:10.1038/sj.jid.5700266

See also: Original Article by Shimomura et al. See also: Original Article by Schaffer et al. See also: Original Article by Zlotogorski et al.
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Original Articles

Appendages

Cutaneous Microdialysis as a Novel Means of Continuously Stimulating Eccrine Sweat Glands In Vivo  FREE

Caroline J Morgan, Peter S Friedmann, Martin K Church and Geraldine F Clough

J Invest Dermatol 126: 1220-1225; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700197

See also: Commentary by Anderson
Insulin-Like Growth Factor-1 Induces Lipid Production in Human SEB-1 Sebocytes Via Sterol Response Element-Binding Protein-1 FREE

Terry M Smith, Zhaoyuan Cong, Kathryn L Gilliland, Gary A Clawson and Diane M Thiboutot

J Invest Dermatol 126: 1226-1232; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700278

Cell Biology

PKCdelta Clustering at the Leading Edge and Mediating Growth Factor-Enhanced, but not ECM-Initiated, Dermal Fibroblast Migration FREE

Jianhua Fan, Shengxi Guan, Chieh-Fang Cheng, Michele Cho, Joshua W Fields, Mei Chen, Mitchell F Denning, David T Woodley and Wei Li

J Invest Dermatol 126: 1233-1243; doi:10.1038/sj.jid.5700149

Clinical Research

Testing and Reducing Skindex-29 Using Rasch Analysis: Skindex-17 FREE

Tamar E C Nijsten, Francesca Sampogna, Mary-Margaret Chren and Damiano D Abeni

J Invest Dermatol 126: 1244-1250; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700212

Imiquimod for Actinic Keratosis: Systematic Review and Meta-Analysis FREE

Gina Hadley, Sheena Derry and Robert A Moore

J Invest Dermatol 126: 1251-1255; advance online publication, March 23, 2006; doi:10.1038/sj.jid.5700264

Photoadaptation during Narrowband Ultraviolet-B Therapy Is Independent of Skin Type: A Study of 352 Patients FREE

Roy A Palmer, Susan Aquilina, Peter J Milligan, Susan L Walker, John L M Hawk and Antony R Young

J Invest Dermatol 126: 1256-1263; advance online publication, April 6, 2006; doi:10.1038/sj.jid.5700287

Connective Tissue

Dexamethasone Induction of Keloid Regression through Effective Suppression of VEGF Expression and Keloid Fibroblast Proliferation FREE

Wen-Sheng Wu, Feng-Sheng Wang, Kuender D Yang, Chao-Cheng Huang and Yur-Ren Kuo

J Invest Dermatol 126: 1264-1271; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700274

Ellagic and Tannic Acids Protect Newly Synthesized Elastic Fibers from Premature Enzymatic Degradation in Dermal Fibroblast Cultures FREE

Felipe Jimenez, Thomas F Mitts, Kela Liu, Yanting Wang and Aleksander Hinek

J Invest Dermatol 126: 1272-1280; advance online publication, April 6, 2006; doi:10.1038/sj.jid.5700285

Genetics

Mutations in the Desmoglein 4 Gene Are Associated with Monilethrix-like Congenital Hypotrichosis FREE

Yutaka Shimomura, Fumiko Sakamoto, Naoyuki Kariya, Kayoko Matsunaga and Masaaki Ito

J Invest Dermatol 126: 1281-1285; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700113

See also: Commentary by Schweizer
Mutations in the Desmoglein 4 Gene Underlie Localized Autosomal Recessive Hypotrichosis with Monilethrix Hairs and Congenital Scalp Erosions FREE

Julie V Schaffer, Hisham Bazzi, Anna Vitebsky, Agnieszka Witkiewicz, Olympia I Kovich, Hideko Kamino, Lawrence S Shapiro, Snehal P Amin, Seth J Orlow and Angela M Christiano

J Invest Dermatol 126: 1286-1291; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700237

See also: Commentary by Schweizer
An Autosomal Recessive Form of Monilethrix Is Caused by Mutations in DSG4: Clinical Overlap with Localized Autosomal Recessive Hypotrichosis FREE

Abraham Zlotogorski, Dina Marek, Liran Horev, Almogit Abu, Dan Ben-Amitai, Liora Gerad, Arieh Ingber, Moshe Frydman, Haike Reznik-Wolf, Daniel A Vardy and Elon Pras

J Invest Dermatol 126: 1292-1296; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700251

See also: Commentary by Schweizer
A Gene Locus Responsible for Reticulate Pigmented Anomaly of the Flexures Maps to Chromosome 17p13.3 FREE

Cheng-Rang Li, Qing-He Xing, Ming Li, Wei Qin, Xue-Zhuang Yue, Xiao-Ju Zhang, Hui-Jun Ma, Da-Guang Wang, Guo-Yin Feng, Wen-Yuan Zhu and Lin He

J Invest Dermatol 126: 1297-1301; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700271

Inversa Acne (Hidradenitis Suppurativa): A Case Report and Identification of the Locus at Chromosome 1p21.1–1q25.3 FREE

Min Gao, Pei-Guang Wang, Yong Cui, Sen Yang, Yu-Hui Zhang, Da Lin, Kai-Yue Zhang, Yan-Hua Liang, Liang-Dan Sun, Kai-Lin Yan, Feng-Li Xiao, Wei Huang and Xue-Jun Zhang

J Invest Dermatol 126: 1302-1306; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700272

See also: Commentary by Irvine & McLean

Immunology/Infection

FK506 Controls CD40L-Induced Systemic Autoimmunity in Mice FREE

Karin Loser, Sandra Balkow, Tetsuya Higuchi, Jenny Apelt, Annegret Kuhn, Thomas A Luger and Stefan Beissert

J Invest Dermatol 126: 1307-1315; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700185

See also: Commentary by Dutz
40 nm, but not 750 or 1,500 nm, Nanoparticles Enter Epidermal CD1a+ Cells after Transcutaneous Application on Human Skin FREE

Annika Vogt, Behazine Combadiere, Sabrina Hadam, Karola M Stieler, Juergen Lademann, Hans Schaefer, Brigitte Autran, Wolfram Sterry and Ulrike Blume-Peytavi

J Invest Dermatol 126: 1316-1322; advance online publication, April 13, 2006; doi:10.1038/sj.jid.5700226

Induction of Epidermolysis Bullosa Acquisita in Mice by Passive Transfer of Autoantibodies from Patients FREE

David T Woodley, Ramin Ram, Arvin Doostan, Pubali Bandyopadhyay, Yi Huang, Jennifer Remington, Yingping Hou, Douglas R Keene, Zhi Liu and Mei Chen

J Invest Dermatol 126: 1323-1330; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700254

Cutaneous Endothelial Cell Activation in Normal Skin of Patients with Dermatitis Herpetiformis Associated with Increased Serum Levels of IL-8, sE-Selectin, and TNF-alpha  FREE

Russell P Hall III, Fumiko Takeuchi, Keith M Benbenisty and Robert D Streilein

J Invest Dermatol 126: 1331-1337; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700277

The Small Antitumoral Immune Response Modifier Imiquimod Interacts with Adenosine Receptor Signaling in a TLR7- and TLR8-Independent Fashion FREE

Michael P Schön, Margarete Schön and Karl-Norbert Klotz

J Invest Dermatol 126: 1338-1347; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700286

Keratinocytes/Epidermis

Rottlerin, a Specific Inhibitor of Protein Kinase C-delta, Impedes Barrier Repair Response by Increasing Intracellular Free Calcium FREE

Bong K Ahn, Se K Jeong, Hee S Kim, Ki J Choi, Jung T Seo, Eung H Choi, Sung K Ahn and Seung H Lee

J Invest Dermatol 126: 1348-1355; advance online publication, March 30, 2006; doi:10.1038/sj.jid.5700244

Hyaluronan–CD44 Interaction Stimulates Keratinocyte Differentiation, Lamellar Body Formation/Secretion, and Permeability Barrier Homeostasis FREE

Lilly Y W Bourguignon, Mohamed Ramez, Eli Gilad, Patrick A Singleton, Mao-Qiang Man, Debra A Crumrine, Peter M Elias and Kenneth R Feingold

J Invest Dermatol 126: 1356-1365; advance online publication, March 23, 2006; doi:10.1038/sj.jid.5700260

Melanocytes/Melanoma

Loss of Proapoptotic Bcl-2-Related Multidomain Proteins in Primary Melanomas Is Associated with Poor Prognosis FREE

Lothar F Fecker, Christoph C Geilen, Georgi Tchernev, Uwe Trefzer, Chalid Assaf, Bachtier M Kurbanov, Constanze Schwarz, Peter T Daniel and Jürgen Eberle

J Invest Dermatol 126: 1366-1371; advance online publication, March 9, 2006; doi:10.1038/sj.jid.5700192

See also: Commentary by Leverkus & Gollnick
Clonal Persistence and Evolution During a Decade of Recurrent Melanoma FREE

Ena Wang, Sonia Voiculescu, Isabelle C Le Poole, Mona El-Gamil, Xin Li, Marianna Sabatino, Paul F Robbins, Brian J Nickoloff and Francesco M Marincola

J Invest Dermatol 126: 1372-1377; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700193

See also: Commentary by Grichnik
Tumor Microenvironment Modulates Hyaluronan Expression: The Lactate Effect FREE

Sri Rajalakshmi Rudrabhatla, Christie L Mahaffey and Mark E Mummert

J Invest Dermatol 126: 1378-1387; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700255

Tumor Biology

Heterogeneous Abnormalities of CCND1 and RB1 in Primary Cutaneous T-Cell Lymphomas Suggesting Impaired Cell Cycle Control in Disease Pathogenesis FREE

Xin Mao, Guy Orchard, Eric C Vonderheid, Peter C Nowell, Martine Bagot, Armand Bensussan, Robin Russell-Jones, Bryan D Young and Sean J Whittaker

J Invest Dermatol 126: 1388-1395; advance online publication, April 13, 2006; doi:10.1038/sj.jid.5700224

Vascular Biology

Carbazole Is a Naturally Occurring Inhibitor of Angiogenesis and Inflammation Isolated from Antipsoriatic Coal Tar FREE

Jack L Arbiser, Baskaran Govindarajan, Traci E Battle, Rebecca Lynch, David A Frank, Masuko Ushio-Fukai, Betsy N Perry, David F Stern, G Tim Bowden, Anquan Liu, Eva Klein, Pawel J Kolodziejski, N Tony Eissa, Chowdhury F Hossain and Dale G Nagle

J Invest Dermatol 126: 1396-1402; advance online publication, April 13, 2006; doi:10.1038/sj.jid.5700276

Wound Healing

The Accelerating Effect of Histamine on the Cutaneous Wound-Healing Process Through the Action of Basic Fibroblast Growth Factor FREE

Yukikazu Numata, Tadashi Terui, Ryuhei Okuyama, Noriyasu Hirasawa, Yoshie Sugiura, Ichiro Miyoshi, Takehiko Watanabe, Atsuo Kuramasu, Hachiro Tagami and Hiroshi Ohtsu

J Invest Dermatol 126: 1403-1409; advance online publication, March 16, 2006; doi:10.1038/sj.jid.5700253

Promotion of Human Dermal Fibroblast Migration, Matrix Remodelling and Modification of Fibroblast Morphology within a Novel 3D Model by Lucilia sericata Larval Secretions FREE

Adele J Horobin, Kevin M Shakesheff and David I Pritchard

J Invest Dermatol 126: 1410-1418; advance online publication, May 4, 2006; doi:10.1038/sj.jid.5700256

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Letter to the Editor

Detection of a Physiological Juvenile Phase and the Central Role of Pericytes in Human Dermal Microvascular Aging FREE

Peter Helmbold, Christine Lautenschläger, Wolfgang Ch Marsch and Ramesh C Nayak

J Invest Dermatol 126: 1419-1421; advance online publication, March 23, 2006; doi:10.1038/sj.jid.5700275

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Abstracts

Abstracts FREE

J Invest Dermatol 126: 1424-1425; doi:10.1038/sj.jid.5700343

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Corrigenda

Corrigendum: Inflammatory Destruction of Elastic Fibers in Acquired Cutis Laxa Is Associated with Missense Alleles in the Elastin and Fibulin-5 Genes FREE

 Hu et al.

J Invest Dermatol 126: 1426; doi:10.1038/sj.jid.5700353

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Errata

Erratum: Long-Term Culture of Murine Epidermal Keratinocytes FREE

 Caldelari et al.

J Invest Dermatol 126: 1426; doi:10.1038/sj.jid.5700354

Erratum: Genetic and Environmental Influences on Skin Pattern Deterioration FREE

 Shekar et al.

J Invest Dermatol 126: 1426-1427; doi:10.1038/sj.jid.5700355

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Corrigenda

Corrigendum: Molecular Epidemiology of Hereditary Epidermolysis Bullosa in a Middle Eastern Population FREE

 Abu Sa'd et al.

J Invest Dermatol 126: 1427; doi:10.1038/sj.jid.5700359

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