TABLE OF CONTENTS

Volume 126, Issue 4 (April 2006)

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Editorials

Albert M. Kligman: 90 Years Old on March 17, 2006 FREE

John R Stanley, Associate Editor

J Invest Dermatol 126: 697-698; doi:10.1038/sj.jid.5700259

Research Snippets FREE

J Invest Dermatol 126: 700; doi:10.1038/sj.jid.5700261

Editors' Picks FREE

J Invest Dermatol 126: 701; doi:10.1038/sj.jid.5700262

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Commentaries

The Focal Nature of Darier's Disease Lesions: Calcium Pumps, Stress, and Mutation? FREE

Carolyn R Byrne

J Invest Dermatol 126: 702-703; doi:10.1038/sj.jid.5700141

See also: Original Article by Müller et al.

Pseudoxanthoma Elasticum: the End of the Autosomal Dominant Segregation Myth FREE

Arthur A B Bergen

J Invest Dermatol 126: 704-705; doi:10.1038/sj.jid.5700129

See also: Original Article by Ringpfeil et al.

Langerhans Cells on Guard in the Epidermis: Poised to dSEARCH and ...? FREE

Mark C Udey

J Invest Dermatol 126: 705-707; doi:10.1038/sj.jid.5700222

See also: Original Article by Nishibu et al.

Fibroblasts as Target Cells for DEB Gene Therapy FREE

Mei Chen and David T Woodley

J Invest Dermatol 126: 708-710; doi:10.1038/sj.jid.5700216

See also: Original Article by Goto et al.
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Original Articles

Appendages

Doxorubicin-Induced Alopecia Is Associated with Sebaceous Gland Degeneration FREE

Silvia Selleri, Holger Seltmann, Silvia Gariboldi, Yuri F Shirai, Andrea Balsari, Christos C Zouboulis and Cristiano Rumio

J Invest Dermatol 126: 711-720; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700175

Cell Biology

Consequences of Depleted SERCA2-Gated Calcium Stores in the Skin FREE

Eliane J Müller, Reto Caldelari, Carine Kolly, Lina Williamson, Dominique Baumann, Gabriele Richard, Pamela Jensen, Peter Girling, Franco Delprincipe, Marianne Wyder, Vreni Balmer and Maja M Suter

J Invest Dermatol 126: 721-731; advance online publication, January 5, 2006; doi:10.1038/sj.jid.5700091

See also: Commentary by Byrne
Retinoid-Induced Epidermal Hyperplasia Is Mediated by Epidermal Growth Factor Receptor Activation Via Specific Induction of its Ligands Heparin-Binding EGF and Amphiregulin in Human Skin In Vivo  FREE

Laure Rittié, James Varani, Sewon Kang, John J Voorhees and Gary J Fisher

J Invest Dermatol 126: 732-739; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700202

Clinical Research

Distinct Clinical Differences Between HLA-Cw*0602 Positive and Negative Psoriasis Patients – An Analysis of 1019 HLA-C- and HLA-B-Typed Patients FREE

Johann E Gudjonsson, Ari Karason, E Hjaltey Runarsdottir, Arna A Antonsdottir, Valdimar B Hauksson, Hjörtur H Jónsson, Jeff Gulcher, Kari Stefansson and Helgi Valdimarsson

J Invest Dermatol 126: 740-745; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700118

See also: Editorial by

Connective Tissue

Functional Characterization and Expression Analysis of the Proteinase-Activated Receptor-2 in Human Cutaneous Mast Cells FREE

Corinna Moormann, Metin Artuc, Elena Pohl, Georg Varga, Jörg Buddenkotte, Nathalie Vergnolle, Randolf Brehler, Beate M Henz, Stefan W Schneider, Thomas A Luger and Martin Steinhoff

J Invest Dermatol 126: 746-755; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700169

Novel Functions of Intracellular IL-1ra in Human Dermal Fibroblasts: Implications in the Pathogenesis of Fibrosis FREE

Siva Kanangat, Arnold E Postlethwaite, Gloria C Higgins and Karen A Hasty

J Invest Dermatol 126: 756-765; advance online publication, February 2, 2006; doi:10.1038/sj.jid.5700097

Genetics

Fibroblasts Show More Potential as Target Cells than Keratinocytes in COL7A1 Gene Therapy of Dystrophic Epidermolysis Bullosa FREE

Maki Goto, Daisuke Sawamura, Kei Ito, Masataka Abe, Wataru Nishie, Kaori Sakai, Akihiko Shibaki, Masashi Akiyama and Hiroshi Shimizu

J Invest Dermatol 126: 766-772; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700117

See also: Commentary by Chen & Woodley
Three Severe Cases of EBS Dowling-Meara Caused by Missense and Frameshift Mutations in the Keratin 14 Gene FREE

Matthias Titeux, Juliette Mazereeuw-Hautier, Smaïl Hadj-Rabia, Catherine Prost, Laure Tonasso, Sylvie Fraitag, Yves de Prost, Alain Hovnanian and Christine Bodemer

J Invest Dermatol 126: 773-776; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700154

Molecular Epidemiology of Hereditary Epidermolysis Bullosa in a Middle Eastern Population FREE

Judeh Abu Sa'd, Margarita Indelman, Ellen Pfendner, Tzipora C Falik-Zaccai, Mordechai Mizrachi-Koren, Stavit Shalev, Dani Ben Amitai, Annick Raas-Rothshild, Ayelet Adir-Shani, Zvi-Uri Borochowitz, Ruth Gershoni-Baruch, Morad Khayat, Daniela Landau, Gabriele Richard, Reuven Bergman, Jouni Uitto, Moien Kanaan and Eli Sprecher

J Invest Dermatol 126: 777-781; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700163

Pseudoxanthoma Elasticum Is a Recessive Disease Characterized by Compound Heterozygosity FREE

Franziska Ringpfeil, Kelly McGuigan, Lauren Fuchsel, Heidi Kozic, Margarita Larralde, Mark Lebwohl and Jouni Uitto

J Invest Dermatol 126: 782-786; advance online publication, January 12, 2006; doi:10.1038/sj.jid.5700115

See also: Commentary by Bergen

Immunology/Infection

Behavioral Responses of Epidermal Langerhans Cells In Situ to Local Pathological Stimuli FREE

Akiko Nishibu, Brant R Ward, James V Jester, Hidde L Ploegh, Marianne Boes and Akira Takashima

J Invest Dermatol 126: 787-796; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700107

See also: Commentary by Udey
Engagement of CD47 Inhibits the Contact Hypersensitivity Response Via the Suppression of Motility and B7 Expression by Langerhans Cells FREE

Xijun Yu, Atsushi Fukunaga, Hiroshi Nagai, Shuntaro Oniki, Nakayuki Honma, Masamitsu Ichihashi, Takashi Matozaki, Chikako Nishigori and Tatsuya Horikawa

J Invest Dermatol 126: 797-807; advance online publication, February 2, 2006; doi:10.1038/sj.jid.5700176

Environmentally Responsive and Reversible Regulation of Epidermal Barrier Function by bold italic gammadelta T Cells FREE

Michael Girardi, Julia M Lewis, Renata B Filler, Adrian C Hayday and Robert E Tigelaar

J Invest Dermatol 126: 808-814; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700120

CD8+ T Cells Are Effector Cells of Contact Dermatitis to Common Skin Allergens in Mice FREE

Marc Vocanson, Anca Hennino, Magalie Cluzel-Tailhardat, Pierre Saint-Mezard, Josette Benetiere, Cyril Chavagnac, Frederic Berard, Dominique Kaiserlian and Jean-François Nicolas

J Invest Dermatol 126: 815-820; advance online publication, February 2, 2006; doi:10.1038/sj.jid.5700174

Topical Imiquimod Treatment Prevents UV-Light Induced Loss of Contact Hypersensitivity and Immune Tolerance FREE

Thomas H Thatcher, Irina Luzina, Rita Fishelevich, Mark A Tomai, Richard L Miller and Anthony A Gaspari

J Invest Dermatol 126: 821-831; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700167

See also: Editorial by
Epitopes in the Linker Subdomain Region of Envoplakin Recognized by Autoantibodies in Paraneoplastic Pemphigus Patients FREE

Bingxin Zhang, Rui Zheng, Jing Wang, Dingfang Bu and Xuejun Zhu

J Invest Dermatol 126: 832-840; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700198

Keratinocytes/Epidermis

Heavy Water Labeling of Keratin as a Non-Invasive Biomarker of Skin Turnover In Vivo in Rodents and Humans FREE

Glen Lindwall, Elaine A Hsieh, Lisa M Misell, Christine M Chai, Scott M Turner and Marc K Hellerstein

J Invest Dermatol 126: 841-848; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700189

Melanocytes/Melanoma

Circulating Tyrosinase and MART-1 mRNA does not Independently Predict Relapse or Survival in Patients with AJCC Stage I–II Melanoma FREE

Henrik Schmidt, Boe S Sorensen, Pia Sjoegren, Ib Jarle Christensen, Kirsten Fode, Jorn Larsen, Ebba Nexo and Hans von der Maase

J Invest Dermatol 126: 849-854; advance online publication, January 12, 2006; doi:10.1038/sj.jid.5700139

sPLA2-X Stimulates Cutaneous Melanocyte Dendricity and Pigmentation Through a Lysophosphatidylcholine-Dependent Mechanism FREE

Glynis A Scott, Stacey E Jacobs and Alice P Pentland

J Invest Dermatol 126: 855-861; advance online publication, February 2, 2006; doi:10.1038/sj.jid.5700180

RhoC Promotes Human Melanoma Invasion in a PI3K/Akt-Dependent Pathway FREE

Mariah C Ruth, Yisheng Xu, Ian H Maxwell, Natalie G Ahn, David A Norris and Yiqun G Shellman

J Invest Dermatol 126: 862-868; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700211

Tumor Biology

Genomic Analysis Defines a Cancer-Specific Gene Expression Signature for Human Squamous Cell Carcinoma and Distinguishes Malignant Hyperproliferation from Benign Hyperplasia FREE

Asifa S Haider, Sara B Peters, Helen Kaporis, Irma Cardinale, Ji Fei, Jurg Ott, Miki Blumenberg, Ann M Bowcock, James G Krueger and John A Carucci

J Invest Dermatol 126: 869-881; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700157

See also: Editorial by

Vascular Biology

Structure–Function Relation of Efomycines, a Family of Small-Molecule Inhibitors of Selectin Functions FREE

B Gregor Wienrich, Thomas Krahn, Margarete Schön, Maria L Rodriguez, Bernd Kramer, Matthias Busemann, W Henning Boehncke and Michael P Schön

J Invest Dermatol 126: 882-889; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700159

Wound Healing

Delayed Cutaneous Wound Healing in Mice Lacking Solute Carrier 11a1 (Formerly Nramp1): Correlation with Decreased Expression of Secretory Leukocyte Protease Inhibitor FREE

Thusanth Thuraisingam, Hakeem Sam, Jacques Moisan, Yi Zhang, Aihao Ding and Danuta Radzioch

J Invest Dermatol 126: 890-901; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700182

Delayed Wound Healing and Epidermal Hyperproliferation in Mice Lacking JunB in the Skin FREE

Lore Florin, Julia Knebel, Paola Zigrino, Birgitta Vonderstrass, Cornelia Mauch, Marina Schorpp-Kistner, Axel Szabowski and Peter Angel

J Invest Dermatol 126: 902-911; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700123

See also: Editorial by
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Letters to the Editor

Increased JunB mRNA and Protein Expression in Psoriasis Vulgaris Lesions FREE

Asifa S Haider, Judilyn Duculan, Julia A Whynot and James G Krueger

J Invest Dermatol 126: 912-914; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700183

Circulating Tumor Cells and Detection of the Melanoma-Associated Antigen HMW-MAA in the Serum of Melanoma Patients FREE

Anja Ulmer and Gerhard Fierlbeck

J Invest Dermatol 126: 915; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700158

Response to: Circulating Tumor Cells and Detection of Melanoma-Associated Antigen HMW-MAA in the Serum of Melanoma Patients FREE

Sandra R Reynolds, Soldano Ferrone and Jean-Claude Bystryn

J Invest Dermatol 126: 916; advance online publication, January 12, 2006; doi:10.1038/sj.jid.5700156

In Vivo and Ex Vivo UV-Induced Analysis of Pigmentation Gene Expressions FREE

Sébastien Corre, Karim Mekideche, Henri Adamski, Jean Mosser, Eric Watier and Marie-Dominique Galibert

J Invest Dermatol 126: 917-919; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700190

See also: Editorial by

An Important Role of Lymphatic Vessels in the Control of UVB-Induced Edema Formation and Inflammation FREE

Kentaro Kajiya and Michael Detmar

J Invest Dermatol 126: 920-922; advance online publication, February 9, 2006; doi:10.1038/sj.jid.5700126

Vascular Biology

Tumor Necrosis Factor Alpha Gene Polymorphism Associated with Increased Susceptibility to Venous Leg Ulceration FREE

Hilary J Wallace, Yvonne K Vandongen and Michael C Stacey

J Invest Dermatol 126: 923-926; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700143

Quantification of Eight Tissue Kallikreins in the Stratum Corneum and Sweat FREE

Nahoko Komatsu, Brian Tsai, Michael Sidiropoulos, Kiyofumi Saijoh, Michael A Levesque, Kazuhiko Takehara and Eleftherios P Diamandis

J Invest Dermatol 126: 927-931; advance online publication, February 2, 2006; doi:10.1038/sj.jid.5700146

Perifollicular and Perivascular Mouse Skin Mast Cells Express Corticotropin-Releasing Hormone Receptor FREE

Jill Donelan, James E Marchand, Duraisamy Kempuraj, Nikoletta Papadopoulou, Dean Papaliodis and Theoharis C Theoharides

J Invest Dermatol 126: 932-935; advance online publication, January 26, 2006; doi:10.1038/sj.jid.5700153

Male Restricted Genetic Association of Variant R620W in PTPN22 with Psoriatic Arthritis FREE

Ulrike Hüffmeier, André Reis, Michael Steffens, Jesús Lascorz, Beate Böhm, Jörg Lohmann, Jörg Wendler, Heiko Traupe, Wolfgang Küster, Thomas F Wienker and Harald Burkhardt

J Invest Dermatol 126: 936-938; advance online publication, February 2, 2006; doi:10.1038/sj.jid.5700179

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