TABLE 1B
FROM:
Quantification of Eight Tissue Kallikreins in the Stratum Corneum and Sweat
Nahoko Komatsu, Brian Tsai, Michael Sidiropoulos, Kiyofumi Saijoh, Michael A Levesque, Kazuhiko Takehara and Eleftherios P Diamandis
BACK TO ARTICLETable 1b. Quantification of kallikreins in sweat from different body regions by ELISA
| Sweat (ng/mg of total protein) | ||||||
|---|---|---|---|---|---|---|
| Region | ||||||
| Face | Axilla | Abdomen | ||||
| hK |
Mean SD
| % |
MeanSD
| % |
MeanSD
| % |
| Chymotrypsin-like hK | ||||||
| hK7 | 345228 | 393306 | 434308 | |||
| M | ||||||
| F | 219165 | 165155 | 262227 | |||
| Trypsin-like hK | ||||||
| hK8 | ||||||
| M | 334207 | 58.0 | 255112 | 52.3 | 23492 | 61.0## |
| F | 379230 | 69.0 | 6249*
1
| 65.7 | 227115 | 67.6 |
| hK11 | ||||||
| M | 13464 | 23.4 | 14771 | 30.1 | 10076 | 26.2 |
| F | 10081 | 18.2 | 125.4*
2
| 12.7 | 7531 | 22.4 |
| hK5 | ||||||
| M | 8.82.3 | 1.5 | 4527*
3
| 9.2 | 1812 | 4.8 |
| F | 1711 | 3.1 | 1413 | 14.3 | 2220 | 6.5 |
| hK10 | ||||||
| M | 4118*
4
| 7.2 | 2118 | 4.3 | 1310 | 3.4# |
| F | 3123*
5
| 5.7 | 4.03.4 | 4.2 | 5.73.1 | 1.7 |
| hK6 | ||||||
| M | 3215*
5
| 5.6 | 7.84.0 | 1.6 | 105.5 | 2.7# |
| F | 121.7 | 2.3 | 1.41.3 | 1.4 | 3.91.5 | 1.2 |
| hK13 | ||||||
| M | 1821*
4
| 3.2 | 7.05.2 | 1.4 | 3.64.2 | 0.9 |
| F | 7.37.2 | 1.3 | 0.900.88 | 1.0 | 1.10.92 | 0.3 |
| hK14 | ||||||
| M | 6.13.4*
4
| 1.1 | 4.82.3 | 1.0 | 4.12.6 | 1.1# |
| F | 1.91.4 | 0.4 | 0.740.71 | 0.8 | 1.00.45 | 0.3 |
| Total of trypsin-like hKs | ||||||
| M | 575183 | 488157 | 383166 | |||
| F | 549221 | 9549*
6
| 33694 | |||
F=female; hK=kallikrein protein; M=male; SC=stratum corneum.
Kallikrein concentrations are in ng/mg total protein. The percentages represent the fraction of each trypsin-like hK within the total amount of trypsin-like hKs.
#Two-way ANOVA displayed significant differences between genders for hK6, hK10, and hK14 (P<0.05 for each). The post hoc test (Bonferroni method to reflect multiple comparisons) showed significant differences (P<0.05 for each) as follows: * 1, F-axilla versus F-face for hK8; * 2F-axilla versus M-axilla for hK11; * 3M-axilla versus M-face and F axilla for hK5; * 4M-face versus M-abdomen for hK6, hK13, and hK14; * 5face versus axilla and abdomen for F-hK10 and M-hK6; * 6F-axilla versus F-face, F-abdomen, and M-axilla for the total concentration of trypsin-like hKs.
##One-way ANOVA revealed significantly higher hK8 levels compared with the other trypsin-like hKs (P<0.05 for each), except in the axilla of females.
