TABLE OF CONTENTS

Volume 126, Issue 2 (February 2006)

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Editorials

How Big Is the Universe? FREE

Lowell A Goldsmith, Editor

J Invest Dermatol 126: 235; doi:10.1038/sj.jid.5700145

Research Snippets FREE

J Invest Dermatol 126: 237; doi:10.1038/sj.jid.5700166

Editors' Picks FREE

J Invest Dermatol 126: 238; doi:10.1038/sj.jid.5700144

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Commentaries

Microchimerism and Skin Disease: True-True Unrelated? FREE

Anita C Gilliam

J Invest Dermatol 126: 239-241; doi:10.1038/sj.jid.5700061

See also: Original Article by Khosrotehrani et al.

(P)PARsing Epidermal Development FREE

Sandrine Dubrac and Matthias Schmuth

J Invest Dermatol 126: 241-242; doi:10.1038/sj.jid.5700137

See also: Original Article by Yang et al.
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Perspectives

Keratinocyte Apoptosis in Epidermal Development and Disease FREE

Deepak Raj, Douglas E Brash and Douglas Grossman

J Invest Dermatol 126: 243-257; doi:10.1038/sj.jid.5700008

Apoptosis in the Hair Follicle FREE

Natalia V Botchkareva, Gurpreet Ahluwalia and Douglas Shander

J Invest Dermatol 126: 258-264; doi:10.1038/sj.jid.5700007

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Original Articles

Clinical Research

Porphyrin Formation in Actinic Keratosis and Basal Cell Carcinoma after Topical Application of Methyl 5-Aminolevulinate FREE

Even Angell-Petersen, Roar Sørensen, Trond Warloe, Ana Maria Soler, Johan Moan, Qian Peng and Karl-Erik Giercksky

J Invest Dermatol 126: 265-271; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700048

Performance of the SCORTEN During the First Five Days of Hospitalization to Predict the Prognosis of Epidermal Necrolysis FREE

Sarah Guégan, Sylvie Bastuji-Garin, Ewa Poszepczynska-Guigné, Jean-Claude Roujeau and Jean Revuz

J Invest Dermatol 126: 272-276; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700068

A Genome Scan for Epidermal Skin Pattern in Adolescent Twins Reveals Suggestive Linkage on 12p13.31 FREE

Sri Niranjan Shekar, David L Duffy, Grant W Montgomery and Nicholas G Martin

J Invest Dermatol 126: 277-282; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700067

Connective Tissue

Inflammatory Destruction of Elastic Fibers in Acquired Cutis Laxa Is Associated with Missense Alleles in the Elastin and Fibulin-5 Genes FREE

Qirui Hu, Jean-Louis Reymond, Nicole Pinel, Marie-Therese Zabot and Zsolt Urban

J Invest Dermatol 126: 283-290; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700047

The Receptor for Advanced Glycation End Products Is Highly Expressed in the Skin and Upregulated by Advanced Glycation End Products and Tumor Necrosis Factor-Alpha FREE

Christina Lohwasser, Daniel Neureiter, Bernd Weigle, Thomas Kirchner and Detlef Schuppan

J Invest Dermatol 126: 291-299; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700070

Genetics

The Gene for a Rare Autosomal Dominant Form of Pompholyx Maps to Chromosome 18q22.1–18q22.3 FREE

Jian-Jun Chen, Yan-Hua Liang, Fu-Sheng Zhou, Sen Yang, Jian Wang, Pei-Guang Wang, Wen-Hui Du, Shi-Jie Xu, Wei Huang and Xue-Jun Zhang

J Invest Dermatol 126: 300-304; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700103

The Distal and Proximal Regulatory Regions of the Involucrin Gene Promoter have Distinct Functions and Are Required for In Vivo Involucrin Expression FREE

James F Crish, Ramamurthy Gopalakrishnan, Frederic Bone, Anita C Gilliam and Richard L Eckert

J Invest Dermatol 126: 305-314; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700019

SPINK5, the Defective Gene in Netherton Syndrome, Encodes Multiple LEKTI Isoforms Derived from Alternative Pre-mRNA Processing FREE

Alessandro Tartaglia-Polcini, Chrystelle Bonnart, Alessia Micheloni, Francesca Cianfarani, Alessandra Andrè, Giovanna Zambruno, Alain Hovnanian and Marina D'Alessio

J Invest Dermatol 126: 315-324; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700015

Transcriptional Regulation and Characterization of the Promoter Region of the Human ABCC6 Gene FREE

Qiujie Jiang, Yasushi Matsuzaki, Kehua Li and Jouni Uitto

J Invest Dermatol 126: 325-335; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700065

Mitochondrial DNA Deletions Serve as Biomarkers of Aging in the Skin, but Are Typically Absent in Nonmelanoma Skin Cancers FREE

Alex Eshaghian, Ruth A Vleugels, Jeffrey A Canter, Michel A McDonald, Thomas Stasko and James E Sligh

J Invest Dermatol 126: 336-344; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700088

Immunology/Infection

Presence of Chimeric Maternally Derived Keratinocytes in Cutaneous Inflammatory Diseases of Children: The Example of Pityriasis Lichenoides FREE

Kiarash Khosrotehrani, Sarah Guegan, Sylvie Fraitag, Michèle Oster, Yves de Prost, Christine Bodemer and Selim Aractingi

J Invest Dermatol 126: 345-348; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700060

See also: Commentary by Gilliam
Identification of Novel Pharmacological Activities of an Antifungal Agent, Nystatin, to Promote Dendritic Cell Maturation FREE

Yasushi Ogawa, Norikatsu Mizumoto, Hiroaki Tanaka, Hironori Matsushima and Akira Takashima

J Invest Dermatol 126: 349-353; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700081

Generation of Multiple Stable Dermcidin-Derived Antimicrobial Peptides in Sweat of Different Body Sites FREE

Siegbert Rieg, Silke Seeber, Heiko Steffen, Andreas Humeny, Hubert Kalbacher, Stefan Stevanovic, Akihiko Kimura, Claus Garbe and Birgit Schittek

J Invest Dermatol 126: 354-365; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700041

Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance FREE

Matthew J Deeths, Bart T Endrizzi, Michelle L Irvin, Lynne P Steiner, Marna E Ericson and Maria K Hordinsky

J Invest Dermatol 126: 366-373; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700054

Keratinocytes/Epidermis

Alterations in Skin and Stratified Epithelia by Constitutively Activated PPARalpha  FREE

Qian Yang, Atsushi Yamada, Shioko Kimura, Jeffrey M Peters and Frank J Gonzalez

J Invest Dermatol 126: 374-385; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700056

See also: Commentary by Dubrac & Schmuth
Basis for Improved Permeability Barrier Homeostasis Induced by PPAR and LXR Activators: Liposensors Stimulate Lipid Synthesis, Lamellar Body Secretion, and Post-Secretory Lipid Processing FREE

Mao-Qiang Man, Eung-Ho Choi, Matt Schmuth, Debra Crumrine, Yoshikazu Uchida, Peter M Elias, Walter M Holleran and Kenneth R Feingold

J Invest Dermatol 126: 386-392; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700046

Melanocytes/Melanoma

Heterogeneity of T-Cell Clones Infiltrating Primary Malignant Melanomas FREE

Amir S Yazdi, Kathrin Morstedt, Ursula Puchta, Kamran Ghoreschi, Michael J Flaig, Martin Rocken and Christian A Sander

J Invest Dermatol 126: 393-398; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700082

Germline CDKN2A Mutations Among Greek Patients with Early-Onset and Multiple Primary Cutaneous Melanoma FREE

Alexander J Stratigos, Guang Yang, Remos Dimisianos, Vasiliki Nicolaou, Irene Stefanaki, Andreas D Katsambas and Hensin Tsao

J Invest Dermatol 126: 399-401; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700078

Detection of UV-Induced Pigmentary and Epidermal Changes Over Time Using In Vivo Reflectance Confocal Microscopy FREE

Maritza A Middelkamp-Hup, H-Y Park, Jin Lee, Barbara A Gilchrest and Salvador Gonzalez

J Invest Dermatol 126: 402-407; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700055

Photobiology

The Incidence of Both Tandem Duplications and the Common Deletion in mtDNA from Three Distinct Categories of Sun-Exposed Human Skin and in Prolonged Culture of Fibroblasts FREE

Kim J Krishnan and Mark A Birch-Machin

J Invest Dermatol 126: 408-415; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700099

Tumor Biology

Chemical Peeling by SA-PEG Remodels Photo-damaged Skin: Suppressing p53 Expression and Normalizing Keratinocyte Differentiation FREE

Teruki Dainichi, Satoshi Amano, Yukiko Matsunaga, Shunsuke Iriyama, Tetsuji Hirao, Takeshi Hariya, Toshihiko Hibino, Chika Katagiri, Motoji Takahashi, Setsuko Ueda and Masutaka Furue

J Invest Dermatol 126: 416-421; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700066

Epigenetic Inactivation of Tumor Suppressor Genes in Serum of Patients with Cutaneous Melanoma FREE

Alessandra Marini, Alireza Mirmohammadsadegh, Sandeep Nambiar, Annett Gustrau, Thomas Ruzicka and Ulrich R Hengge

J Invest Dermatol 126: 422-431; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700073

Vascular Biology

Overexpression of Laminin-8 in Human Dermal Microvascular Endothelial Cells Promotes Angiogenesis-Related Functions FREE

Jie Li, Lisa Zhou, Hoang T Tran, Yi Chen, Ngon E Nguyen, Marvin A Karasek and M Peter Marinkovich

J Invest Dermatol 126: 432-440; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700089

Increased Neutrophil Adherence in Psoriasis: Role of the Human Endothelial Cell Receptor Thy-1 (CD90) FREE

Anne Wetzel, Tino Wetzig, Uwe F Haustein, Michael Sticherling, Ulf Anderegg, Jan C Simon and Anja Saalbach

J Invest Dermatol 126: 441-452; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700072

Interaction between Genetic Control of Vascular Endothelial Growth Factor Production and Retinoid Responsiveness in Psoriasis FREE

Helen S Young, Angela M Summers, Ian R Read, David A Fairhurst, Darren J Plant, Emanuela Campalani, Catherine H Smith, Jonathan N W N Barker, Michael J Detmar, Paul E C Brenchley and Christopher E M Griffiths

J Invest Dermatol 126: 453-459; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700096

Regulation of Skin Microvasculature Angiogenesis, Cell Migration, and Permeability by a Specific Inhibitor of PKCalpha  FREE

Sirosh M Bokhari, Lisa Zhou, Marvin A Karasek, Sarita G Paturi and Vaishali Chaudhuri

J Invest Dermatol 126: 460-467; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700071

Wound Healing

Involvement of the CXCL12/CXCR4 Pathway in the Recovery of Skin Following Burns FREE

Shani Avniel, Zaretski Arik, Alex Maly, Assa Sagie, Hanna Ben Basst, Merav Darash Yahana, Ido D Weiss, Boaz Pal, Ori Wald, Dean Ad-El, Nobutaka Fujii, Fernando Arenzana-Seisdedos, Steffen Jung, Eithan Galun, Eyal Gur and Amnon Peled

J Invest Dermatol 126: 468-476; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700069

The Suppressor of Cytokine Signaling-3 Is Upregulated in Impaired Skin Repair: Implications for Keratinocyte Proliferation FREE

Itamar Goren, Andreas Linke, Elke Müller, Josef Pfeilschifter and Stefan Frank

J Invest Dermatol 126: 477-485; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700063

Epidermal Development and Wound Healing in Matrix Metalloproteinase 13-Deficient Mice FREE

Bettina Hartenstein, Bernd Thilo Dittrich, Dominique Stickens, Babette Heyer, Thiennu H Vu, Sibylle Teurich, Marina Schorpp-Kistner, Zena Werb and Peter Angel

J Invest Dermatol 126: 486-496; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700084

Numerous Keratinocyte Subtypes Involved in Wound Re-Epithelialization FREE

Girish K Patel, Catherine H Wilson, Keith G Harding, Andrew Y Finlay and Paul E Bowden

J Invest Dermatol 126: 497-502; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700101

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Letters to the Editor

The Human Dermokine Gene: Description of Novel Isoforms with Different Tissue-Specific Expression and Subcellular Location FREE

Eve Toulza, Marie-Florence Galliano, Nathalie Jonca, Hélène Gallinaro, Marie-Claire Méchin, Akemi Ishida-Yamamoto, Guy Serre and Marina Guerrin

J Invest Dermatol 126: 503-506; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700033

Massive Recruitment of Type I Interferon Producing Plasmacytoid Dendritic Cells in Varicella Skin Lesions FREE

Gianni Gerlini, Giulia Mariotti, Beatrice Bianchi and Nicola Pimpinelli

J Invest Dermatol 126: 507-509; advance online publication, December 22, 2005; doi:10.1038/sj.jid.5700052

Expression of Neutrophil Gelatinase-Associated Lipocalin in Skin Epidermis FREE

Seong Jun Seo, Ji-Young Ahn, Chang-Kwun Hong, Eun-Young Seo, Kyung-Chae Kye, Woong-Hee Lee, Sang-Keun Lee, Jong-Soon Lim, Myong-Joon Hahn, Lars Kjeldsen, Niels Borregaard, Chang Deok Kim, Jang-Kyu Park and Jeung-Hoon Lee

J Invest Dermatol 126: 510-512; advance online publication, December 29, 2005; doi:10.1038/sj.jid.5700035

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