Journal of Investigative Dermatology - Figure 1 for article: Generalized Epidermolytic Hyperkeratosis in Two Unrelated Children from Parents with Localized Linear Form, and Prenatal Diagnosis

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Generalized Epidermolytic Hyperkeratosis in Two Unrelated Children from Parents with Localized Linear Form, and Prenatal Diagnosis

Nicolas Chassaing, Jean Kanitakis, Stéphanie Sportich, Marie-Pierre Cordier-Alex, Matthias Titeux, Patrick Calvas, Alain Claudy, P Berbis and Alain Hovnanian

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Clinical features and ultrastructural analysis of patient 1 and his mother. (a) At birth the proband's skin was diffusely erythematous with superficial blistering and erosive lesions leading to diffuse scaling. (b) Electronmicroscopic examination shows vacuolated keratinocytes of the upper epidermal layers, containing tonofilament clumps; bar=1.2 m. (c) The mother of patient 1 displays congenital keratotic papula over the left hand, the arm, and forearm.

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FIGURE 1

Generalized Epidermolytic Hyperkeratosis in Two Unrelated Children from Parents with Localized Linear Form, and Prenatal Diagnosis

Figure 1.