Commentary
Journal of Investigative Dermatology (2006) 126, 2156–2158. doi:10.1038/sj.jid.5700417
Photoadaptation: A Path Toward Rational Phototherapy Protocols
Iltefat Hamzavi1
1Department of Dermatology, Henry Ford Hospital, Detroit, Michigan, USA
Correspondence: Dr. Iltefat Hamzavi, Department of Dermatology, Henry Ford Hospital, 3031 West Grand Boulevard, Suite 800, Detroit, Michigan 48202, USA. E-mail: iham2av1@hfhs.org
Abstract
Photoadaptation is defined as the diminished future response to equivalent doses of irradiation. It is most often estimated in vivo by looking at changes in the minimal erythema dose with subsequent doses of UV radiation. Although photoadaptation's mechanism of action is poorly understood, Palmer et al. help clarify the clinical significance of photoadaptation for the dosimetry of UV-based phototherapy.
