Letter to the Editor

Journal of Investigative Dermatology (2005) 125, 395–396; doi:10.1111/j.0022-202X.2005.23802.x

Protein Tyrosine Phosphatase Gene PTPN22 Polymorphism in Psoriasis: Lack of Evidence for Association

Ioana Nistor*, Rajan P Nair*, Philip Stuart*, Ravi Hiremagalore*, Rachel A Thompson*, Stefan Jenisch, Michael Weichenthal, Gonçalo R Abecasis§, Zhaohui S Qin§, Enno Christophers, Henry W Lim, John J Voorhees* and James T Elder*,parallel,#

  1. *Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA
  2. Departments of Immunology and University of Kiel , Kiel, Germany
  3. Departments of Dermatology, University of Kiel, Kiel, Germany
  4. §Department of Biostatistics, Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA
  5. Department of Dermatology, Henry Ford Hospital, Detroit, Michigan, USA
  6. parallelDepartment of Radiation Oncology (Cancer Biology), University of Michigan Medical School, Ann Arbor, Michigan, USA
  7. #Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA

Correspondence: James T. Elder, 3312 CCGC, Box 0932, University of Michigan, Ann Arbor, Michigan 48109-0932, USA. Email: jelder@umich.edu

Received 18 February 2005; Revised 16 March 2005; Accepted 21 March 2005.

Abbreviations:

FBAT, family-based association test; GD, Graves disease; GRR, genotype relative risk; GRR1, genotype relative risk for carriers of one copy of the test allele; GRR2, genotype relative risk for carriers of two copies of the test allele; PDT, pedigree disequilibrium test; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SNP, single nucleotide polymorphism; T1D, type 1 diabetes; TDT, transmission/disequilibrium test

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