TABLE I
FROM:
Proteome Analysis of Skin Distinguishes Acute Guttate from Chronic Plaque Psoriasis
Lina M Carlén, Fabio Sánchez, Ann-Charlotte Bergman, Susanne Becker, Daniel Hirschberg, Bo Franzén, Jonathan Coffey, Hans Jörnvall, Gert Auer, Ayodele A Alaiya and Mona Ståhle
BACK TO ARTICLETable I. Proteins with more than 2-fold change in plaque psoriasis compared with normal skin
| Protein | Lesional plaque | Lesional guttate | Non-lesional guttate | Eczema |
|---|---|---|---|---|
| SCCA-2, high pI | 171 | 38 | 1.8 | 4.3 |
| SCCA-2, low pI | 139 | 31 | -5.5 | 3.4 |
| Maspin | 1.9 | -1.3 | -1.1 | -2.1 |
| Cytokeratin 10 | ND | -9 | -2.8 | -1.6 |
| Cytokeratin 14 | 30 | 4 | -1.1 | -1.6 |
| Cytokeratin 15 | -15 | -1.3 | 1.2 | -1.3 |
| Cytokeratin 17 | 9 | 5 | -1.5 | 1.4 |
GST- | 2 | -1.1 | -1.2 | -1.3 |
| HSP27 | 2 | -1.1 | 1.2 | -1.5 |
| RhoGDI 1 | 11 | 5 | 2.3 | 12.4 |
| Calreticulin | -3 | -1.1 | -1.9 | 1.9 |
14–3–3  | 3 | -1.4 | -1.4 | 1.1 |
The fold change between groups is calculated on the basis of average expression level in each sample type.
SCCA-2, squamous cell carcinoma antigen-2; GST, glutathione S transferase; HSP, heat shock protein; RhoGDI, RhoGDP dissociation inhibitor; ND, not detected; bold, upregulated; –, downregulated.
