Journal of Investigative Dermatology

FIGURE 2

FROM:

The Development and Characterization of an In Vitro Model of Psoriasis

Carol L Barker, Mark T McHale, Angela K Gillies, John Waller, David M Pearce, Joy Osborne, Peter E Hutchinson, Gill M Smith and James H Pringle

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Figure 2.

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Proliferation of keratinocytes in normal and psoriatic models of human skin. Figure shows the mean number of Ki67 positive cells in normal (open columns), involved (black filled columns) and uninvolved (gray filled columns) psoriatic models cultured for 7, 14, and 21 d. Models derived from involved or uninvolved psoriatic skin showed higher rates of proliferation compared to normal models p<0.02 n=4. Proliferation rates were similar after 7 and 14 d culture but were significantly reduced after 21 d for all cases tested p<0.002. Error bars represent+SD.

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