Letter to the Editor

Journal of Investigative Dermatology (2004) 123, 603–606; doi:10.1111/j.0022-202X.2004.23226.x

Barrier Function in Transgenic Mice Overexpressing K16, Involucrin, and Filaggrin in the Suprabasal Epidermis

Richard B Presland*, Pierre A Coulombe, Richard L Eckert, Man Mao-Qiang§, Kenneth R Feingold§ and Peter M Elias§

  1. *Departments of Oral Biology and Medicine (Dermatology), University of Washington, Seattle, Washington, USA
  2. Departments of Biological Chemistry and Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  3. Departments of Physiology and Biophysics, Dermatology, Biochemistry, Reproductive Biology, and Oncology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
  4. §Departments of Dermatology and Medicine, University of California, San Francisco, and Dermatology Service, VA Medical Center, San Francisco, California, USA

Correspondence: Richard B. Presland, PhD, Department of Oral Biology, Box 357132, University of Washington, Seattle, WA 98195-7132, USA Email: rp@u.washington.edu

Received 26 November 2003; Revised 3 March 2004; Accepted 29 March 2004; Published online 6 August 2004.

Abbreviations:

CE, cornified envelope; LB, lamellar bodies; PB, permeability barrier; TEWL, transepidermal water loss

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