TABLE OF CONTENTS
Volume 122, Issue 5 (May 2004)
Editorials
Clinical Snippets FREE
Lowell A Goldsmith
J Invest Dermatol 122: v-v; advance online publication, May 5, 2004; doi:10.1111/j.1523-1747.2004.22536.x
Research Snippets FREE
J Invest Dermatol 122: vi-vi; advance online publication, May 5, 2004; doi:10.1111/j.1523-1747.2004.22542.x
In This Issue—Oncogenes, Tumor Suppressor Genes and Melanocytic Lesions FREE
Mark C Udey and Thomas J Hornyak
J Invest Dermatol 122: vii-viii; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22539.x
Connecting Wounds with Connexins FREE
Malcolm B Hodgins
J Invest Dermatol 122: ix-x; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22535.x
The Epidermal Lamellar Body: A Fascinating Secretory Organelle FREE
Manigé Fartasch
J Invest Dermatol 122: xi-xii; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22541.x
Immunopathological Mechanisms of Acantholysis in Pemphigus Vulgaris: An Explanation by Ultrastructural Observations FREE
Zhi Liu, Ning Li and Luis A Diaz
J Invest Dermatol 122: xiii-xiv; doi:10.1111/j.0022-202X.2004.22438.x
Imiquimod: Unexpected Killer FREE
Martin Leverkus
J Invest Dermatol 122: xv-xvi; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22537.x
Bullous Pemphigoid: What Is the Prognosis? FREE
Robert A Swerlick and Neil J Korman
J Invest Dermatol 122: xvii-xviii; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22538.x
Reviews
The Bone Marrow Is Akin to Skin: HCELL and the Biology of Hematopoietic Stem Cell Homing FREE
Robert Sackstein
J Invest Dermatol 122: 1061-1069; doi:10.1111/j.0022-202X.2004.09301.x
Staphylococcus aureus exfoliative toxins: How they cause disease FREE
J Invest Dermatol 122: 1070-1077; doi:10.1111/j.1523-1747.2004.22144.x
Original Articles
Appendages
On the Regulation of Hair Keratin Expression: Lessons from Studies in Pilomatricomas FREE
Bernard Cribier, Bernard Peltre, Edouard Grosshans, Lutz Langbein and Jürgen Schweizer
J Invest Dermatol 122: 1078-1083; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22513.x
Cell Biology
Bulge- and Basal Layer-Specific Expression of Fibroblast Growth Factor-13 (FHF-2) in Mouse Skin FREE
Mitsuko Kawano, Satoshi Suzuki, Masashi Suzuki, Junko Oki and Toru Imamura
J Invest Dermatol 122: 1084-1090; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22514.x
Clinical Research
Mortality Rate of Bullous Pemphigoid in a US Medical Center FREE
Rand L Colbert, David M Allen, Daniel Eastwood and Janet A Fairley
J Invest Dermatol 122: 1091-1095; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22504.x
Connective Tissue
Loss of EPC-1/PEDF Expression During Skin Aging In Vivo FREE
Mary Kay Francis, Stacia Appel, Christine Meyer, Samuel J Balin, Arthur K Balin and Vincent J Cristofalo
J Invest Dermatol 122: 1096-1105; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22510.x
Genetics
Psoriatic Arthritis and CARD15 Gene Polymorphisms: No Evidence for Association in the Italian Population FREE
Emiliano Giardina, Giuseppe Novelli, Antonio Costanzo, Steven Nisticò, Cristina Bulli, Cecilia Sinibaldi, Maria Laura Sorgi, Sergio Chimenti, Francesco Pallone, Egisto Taccari and Paola Borgiani
J Invest Dermatol 122: 1106-1107; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22524.x
Genetic Heterogeneity of KID Syndrome: Identification of a Cx30 Gene (GJB6) Mutation in a Patient with KID Syndrome and Congenital Atrichia FREE
Amy Y Jan, Shivan Amin, Paulina Ratajczak, Gabriele Richard and Virginia P Sybert
J Invest Dermatol 122: 1108-1113; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22518.x
Triple Helix-Mediated Inhibition of Gene Expression Is Increased by PUVA FREE
Robert Besch, Christoph Marschall, Theda Schuh, Carine Giovannangeli, Claudia Kammerbauer and Klaus Degitz
J Invest Dermatol 122: 1114-1120; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22521.x
Identification of a Locus for Punctate Palmoplantar Keratodermas at Chromosome 8q24.13–8q24.21 FREE
Xue-Jun Zhang, Ming Li, Tian-Wen Gao, Ping-Ping He, Sheng-Cai Wei, Jiang-Bo Liu, Cheng-Rang Li, Yong Cui, Sen Yang, Wen-Tao Yuan, Chun-Ying Li, Yu-Feng Liu, Shi-Jie Xu and Wei Huang
J Invest Dermatol 122: 1121-1125; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22507.x
Genome Scans Provide Evidence for Keloid Susceptibility Loci on Chromosomes 2q23 and 7p11 FREE
Alexander G Marneros, James E C Norris, Shoji Watanabe, Ernst Reichenberger and Bjorn R Olsen
J Invest Dermatol 122: 1126-1132; doi:10.1111/j.0022-202X.2004.22327.x
Immunology/Infection
Genetic Polymorphisms of Killer Cell Immunoglobulin-Like Receptors Are Associated with Susceptibility to Psoriasis Vulgaris FREE
Yu Suzuki, Yoshiaki Hamamoto, Yumie Ogasawara, Kimi Ishikawa, Yoshiaki Yoshikawa, Takehiko Sasazuki and Masahiko Muto
J Invest Dermatol 122: 1133-1136; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22517.x
Epidermal Lamellar Granules Transport Different Cargoes as Distinct Aggregates FREE
Akemi Ishida-Yamamoto, Michel Simon, Mari Kishibe, Yuki Miyauchi, Hidetoshi Takahashi, Shigetaka Yoshida, Timothy J O'Brien, Guy Serre and Hajime Iizuka
J Invest Dermatol 122: 1137-1144; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22515.x
IgG Binds to Desmoglein 3 in Desmosomes and Causes a Desmosomal Split Without Keratin Retraction in a Pemphigus Mouse Model FREE
Atsushi Shimizu, Akira Ishiko, Takayuki Ota, Kazuyuki Tsunoda, Masayuki Amagai and Takeji Nishikawa
J Invest Dermatol 122: 1145-1153; doi:10.1111/j.0022-202X.2004.22426.x
Characterization of the Sensitizing Potential of Chemicals by In Vitro Analysis of Dendritic Cell Activation and Skin Penetration FREE
Pierre Aeby, Christoph Wyss, Heinz Beck, Peter Griem, Heike Scheffler and Carsten Goebel
J Invest Dermatol 122: 1154-1164; doi:10.1111/j.0022-202X.2004.22402.x
A Model System Using Tape Stripping for Characterization of Langerhans Cell-Precursors In Vivo FREE
Sandra Holzmann, Christoph H Tripp, Matthias Schmuth, Katrin Janke, Franz Koch, Sem Saeland, Patrizia Stoitzner and Nikolaus Romani
J Invest Dermatol 122: 1165-1174; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22520.x
Induction of RANTES by TWEAK/Fn14 Interaction in Human Keratinocytes FREE
Long Jin, Atsuhito Nakao, Masafumi Nakayama, Noriko Yamaguchi, Yuko Kojima, Nobuhiro Nakano, Ryoji Tsuboi, Ko Okumura, Hideo Yagita and Hideoki Ogawa
J Invest Dermatol 122: 1175-1179; doi:10.1111/j.0022-202X.2004.22419.x
Keratinocytes/Epidermis
FOXE1, A New Transcriptional Target of GLI2 Is Expressed in Human Epidermis and Basal Cell Carcinoma FREE
Thomas Eichberger, Gerhard Regl, Mohammed S Ikram, Graham W Neill, Michael P Philpott, Fritz Aberger and Anna-Maria Frischauf
J Invest Dermatol 122: 1180-1187; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22505.x
Keratinocyte-Releasable Stratifin Functions as a Potent Collagenase-Stimulating Factor in Fibroblasts FREE
Aziz Ghahary, Feridoun Karimi-Busheri, Yvonne Marcoux, Yunyaun Li, Edward E Tredget, Ruhangiz Taghi Kilani, Liang Li, Jing Zheng, Ali Karami, Bernd O Keller and Michael Weinfeld
J Invest Dermatol 122: 1188-1197; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22519.x
Insulin-like Growth Factors (IGF) and IGF-Binding Proteins Bound to Vitronectin Enhance Keratinocyte Protein Synthesis and Migration FREE
Carolyn Hyde, Brett Hollier, Alex Anderson, Damien Harkin and Zee Upton
J Invest Dermatol 122: 1198-1206; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22527.x
Expression of Cholesterol Sulfotransferase (SULT2B1b) in Human Skin and Primary Cultures of Human Epidermal Keratinocytes FREE
Yuko Higashi, Hirotoshi Fuda, Hidekatsu Yanai, Young Lee, Tomoko Fukushige, Tamotsu Kanzaki and Charles A Strott
J Invest Dermatol 122: 1207-1213; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22416.x
Proteinase-Activated Receptor-2 Stimulates Prostaglandin Production in Keratinocytes: Analysis of Prostaglandin Receptors on Human Melanocytes and Effects of PGE2 and PGF2
on Melanocyte Dendricity FREE
Glynis Scott, Sonya Leopardi, Stacey Printup, Namrita Malhi, Miri Seiberg and Randi Lapoint
J Invest Dermatol 122: 1214-1224; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22516.x
Characterization of Kdap, A Protein Secreted by Keratinocytes FREE
Shuichi Tsuchida, Makoto Bonkobara, James R McMillan, Masashi Akiyama, Tatsuo Yudate, Yoshinori Aragane, Tadashi Tezuka, Hiroshi Shimizu, Ponciano D Cruz Jr and Kiyoshi Ariizumi
J Invest Dermatol 122: 1225-1234; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22511.x
Degradation of Corneodesmosome Proteins by Two Serine Proteases of the Kallikrein Family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7 FREE
Cécile Caubet, Nathalie Jonca, Maria Brattsand, Marina Guerrin, Dominique Bernard, Rainer Schmidt, Torbjörn Egelrud, Michel Simon and Guy Serre
J Invest Dermatol 122: 1235-1244; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22512.x
Melanocytes/Melanoma
Tandem BRAF Mutations in Primary Invasive Melanomas FREE
Nancy E Thomas, Audrey Alexander, Sharon N Edmiston, Eloise Parrish, Robert C Millikan, Marianne Berwick, Pamela Groben, David W Ollila, Dianne Mattingly and Kathleen Conway
J Invest Dermatol 122: 1245-1250; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22523.x
Tyrosine-Induced Melanogenesis Shows Differences in Morphologic and Melanogenic Preferences of Melanosomes from Light and Dark Skin Types FREE
Frans van Nieuwpoort, Nico P M Smit, Ria Kolb, Hans van der Meulen, Henk Koerten and Stan Pavel
J Invest Dermatol 122: 1251-1255; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22533.x
The Epidermal Stem Cell Factor Is Over-Expressed in Lentigo Senilis: Implication for the Mechanism of Hyperpigmentation FREE
Hideko Hattori, Makoto Kawashima, Yoshiaki Ichikawa and Genji Imokawa
J Invest Dermatol 122: 1256-1265; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22503.x
Death Receptor-Independent Apoptosis in Malignant Melanoma Induced by the Small-Molecule Immune Response Modifier Imiquimod FREE
Michael P Schön, B Gregor Wienrich, Claudia Drewniok, Anne B Bong, Jürgen Eberle, Christoph C Geilen, Harald Gollnick and Margarete Schön
J Invest Dermatol 122: 1266-1276; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22528.x
Photobiology
Induction of the Photoaging-Associated Mitochondrial Common Deletion In Vivo in Normal Human Skin FREE
Mark Berneburg, Heidi Plettenberg, Kathrin Medve-König, Annette Pfahlberg, H Gers-Barlag, Olaf Gefeller and Jean Krutmann
J Invest Dermatol 122: 1277-1283; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22502.x
Tumor Biology
p16INK4a and p14ARF Tumor Suppressor Genes Are Commonly Inactivated in Cutaneous Squamous Cell Carcinoma FREE
Victoria L Brown, Catherine A Harwood, Tim Crook, James G Cronin, David P Kelsell and Charlotte M Proby
J Invest Dermatol 122: 1284-1292; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22501.x
Truncation of Activated Leukocyte Cell Adhesion Molecule: A Gateway to Melanoma Metastasis FREE
Léon C L T van Kempen, Friedegund Meier, Mikala Egeblad, Monique J F Kersten-Niessen, Claus Garbe, Ulrich H Weidle, Goos N P van Muijen, Meenhard Herlyn, Henri P J Bloemers and Guido W M Swart
J Invest Dermatol 122: 1293-1301; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22531.x
Reduced Expression of Insulin-Like Growth Factor-Binding Protein-3 (IGFBP-3) in Squamous Cell Carcinoma Complicating Recessive Dystrophic Epidermolysis Bullosa FREE
Rajeev Mallipeddi, Vesarat Wessagowit, Andrew P South, Alistair M Robson, Guy E Orchard, Robin A J Eady and John A McGrath
J Invest Dermatol 122: 1302-1309; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22525.x
Wound Healing
Connexins 26, 30, and 43: Differences Among Spontaneous, Chronic, and Accelerated Human Wound Healing FREE
Johanna M Brandner, Pia Houdek, Birgit Hüsing, Colette Kaiser and Ingrid Moll
J Invest Dermatol 122: 1310-1320; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22529.x
Letters to the Editor
Cryptic Splicing at a Non-Consensus Splice-Donor in a Patient with a Novel Mutation in the Plakophilin-1 Gene FREE
Peter M Steijlen, Maurice A M van Steensel, Bastiaan J H Jansen, Willeke Blokx, Peter C M van de Kerkhof, Rudolf Happle and Michel van Geel
J Invest Dermatol 122: 1321-1324; doi:10.1111/j.0022-202X.2003.22302.x
Lack of BRAF Mutations in Spitz nevi FREE
Melissa Gill, Neil Renwick, David N Silvers and Jülide Tok Çelebi
J Invest Dermatol 122: 1325-1326; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22530.x
CDKN2A and MC1R Mutations in Patients with Sporadic Multiple Primary Melanoma FREE
Ketty Peris, Maria Concetta Fargnoli, Alessia Pacifico, Tiziana Surrenti, Wilhem Stolz, Peter Wolf, Hans Peter Soyer and Sergio Chimenti
J Invest Dermatol 122: 1327-1330; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22532.x
Expression and Regulation of RANTES/CCL5, MIP-1
/CCL3, and MIP-1
/CCL4 in Mouse Langerhans Cells FREE
Hideki Fujita, Akihiko Asahina, Ping Gao, Hiromi Fujiwara and Kunihiko Tamaki
J Invest Dermatol 122: 1331-1333; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22534.x
No Association Between p53 Codon 72 Polymorphisms and Erythemal Response FREE
Claire Manson, Lisa Naysmith, Karen Waterston, David W Melton and Jonathan L Rees
J Invest Dermatol 122: 1334-1335; doi:10.1111/j.0022-202X.2004.22526.x
Identification of an HLA-A3-Restricted Cytotoxic T Lymphocyte (CTL) Epitope from ML-IAP FREE
Mads Hald Andersen, Jürgen C Becker and Per thor Straten
J Invest Dermatol 122: 1336-1337; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22508.x
Methimazole Is an Inhibitor of Melanin Synthesis in Cultured B16 Melanocytes FREE
Behrooz Kasraee, Ambros Hügin, Christian Tran, Olivier Sorg and Jean-Hilaire Saurat
J Invest Dermatol 122: 1338-1341; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22509.x
Langerhans Cell Resistance, CD11b+ Cell Influx, and Cytokine mRNA Expression in Skin after UV Exposure in Patients with Polymorphous Light Eruption as Compared with Healthy Control Subjects FREE
Alexandra Wackernagel, Barbara Bäck, Franz Quehenberger, Lorenzo Cerroni, Helmut Kerl and Peter Wolf
J Invest Dermatol 122: 1342-1344; advance online publication, May 5, 2004; doi:10.1111/j.0022-202X.2004.22506.x



