Original Article

Subject Categories: Clinical Research

Journal of Investigative Dermatology (2004) 122, 873–877; doi:10.1111/j.0022-202X.2004.22406.x

Incidence of Hand Eczema—A Population-Based Retrospective Study

Birgitta Meding*, and Bengt Järvholm

  1. *Occupational Dermatology, National Institute for Working Life, Stockholm, Sweden
  2. Occupational and Environmental Dermatology, Karolinska Institutet and Stockholm County Council, Department of Medicine, Stockholm, Sweden
  3. Occupational Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden

Correspondence: Birgitta Meding, Occupational Dermatology, National Institute for Working Life, Stockholm SE-113 91, Sweden. Email: birgitta.meding@nivl.se

Received 14 May 2003; Revised 23 October 2003; Accepted 29 October 2003.

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Abstract

When etiological relationship is of interest, the incidence rate is a preferred measure. The aim of the present retrospective study was to estimate the incidence rate of self-reported hand eczema in a sample from the general population and to study the relation of this to age, sex, and atopy. A questionnaire was mailed to 3000 individuals aged 20–65 y, randomly selected from the population register of Göteborg, Sweden. This gave a response rate of 73.9%. Questions were asked about ever having had hand eczema, time of onset of the disease, history of childhood eczema, and history of asthma/hay fever. The crude incidence rate of self-reported hand eczema was 5.5 cases per 1000 person-years (females 7.1 and males 4.0). There was no difference, however, in incidence rate between women and men above 30 y of age. In a Poisson regression analysis, female sex, childhood eczema, and asthma/hay fever were all significantly associated with hand eczema, but only at ages below 30 y. A moderate influence of recall bias and a probable tendency to underreport imply that the incidence rates presented are to be considered as minimum rates.

Keywords:

atopy history, epidemiology, general population, relative risk, recall bias

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