TABLE OF CONTENTS
Volume 121, Issue 6 (December 2003)
Editorials
Clinical Snippets FREE
Lowell A Goldsmith
J Invest Dermatol 121: v-v; doi:10.1111/j.1523-1747.2003.12649.x
In This Issue FREE
Jonathan Rees
J Invest Dermatol 121: vi-vi; doi:10.1111/j.1523-1747.2003.12657.x
See also: Original Article by Birklein et al. See also: Original Article by Treumer et al. See also: Original Article by Struijk et al. See also: Letter to the Editor by Nyholt et al.A Mouthful of Epithelial–Mesenchymal Interactions FREE
Michael W Hughes and Cheng-Ming Chuong
J Invest Dermatol 121: vii-viii; doi:10.1111/j.1523-1747.2003.12651.x
See also: Original Article by Costea et al.Cell Movement in the Hair Follicle Dermis – More Than a Two-Way Street? FREE
Colin A B Jahoda
J Invest Dermatol 121: ix-xi; doi:10.1111/j.1523-1747.2003.12585.x
See also: Original Article by Mc Elwee et al.P for Probability and p for p53 FREE
Jonathan Rees
J Invest Dermatol 121: xii-xiii; doi:10.1111/j.1523-1747.2003.12652.x
See also: Original Article by Shen et al.Assessment of Itch: More to be Learned and Improvements to be Made FREE
Gil Yosipovitch
J Invest Dermatol 121: xiv-xv; doi:10.1111/j.1523-1747.2003.12650.x
Letters to the Editors
Author Index for Volume 121 FREE
J Invest Dermatol 121: xvii-xxxiii; doi:10.1111/j.1523-1747.2003.index.x
Original Articles
Appendages
Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla FREE
Kevin J Mc Elwee, Sabine Kissling, Elke Wenzel, Andrea Huth and Rolf Hoffmann
J Invest Dermatol 121: 1267-1275; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12568.x
See also: Editorial by JahodaType II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles FREE
Zhiling Wang, Pauline Wong, Lutz Langbein, Jürgen Schweizer and Pierre A Coulombe
J Invest Dermatol 121: 1276-1282; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12644.x
Cell Biology
Inhibition of the Transforming Growth Factor-
/Smad Signaling Pathway in the Epithelium of Oral Lichen FREE
Andreas Karatsaidis, Olav Schreurs, Tony Axéll, Kristen Helgeland and Karl Schenck
J Invest Dermatol 121: 1-8; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12633.x
Cross-Talk Between RhoGTPases and Stress Activated Kinases for Matrix Metalloproteinase-9 Induction in Response to Keratinocytes Injury FREE
Laurent Turchi, Anne-Amandine Chassot, Isabelle Bourget, Christine Baldescchi, Jean Paul Ortonne, Guerrino Meneguzzi, Emmanuel Lemichez and Gilles Ponzio
J Invest Dermatol 121: 1291-1300; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12627.x
Clinical Research
Perceptual Matching for Assessment of Itch; Reliability and Responsiveness Analyzed by a Rank-Invariant Statistical Method FREE
Elisabet Stener-Victorin, Thomas Lundeberg, Jan Kowalski, Lars Opdal, Johan Sjöström and Lena Lundeberg
J Invest Dermatol 121: 1301-1305; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12622.x
See also: Editorial by GoldsmithSee also: Editorial by YosipovitchEpidermal Overexpression of Interleukin-19 and -20 mRNA in Psoriatic Skin Disappears After Short-Term Treatment with Cyclosporine A or Calcipotriol FREE
John Rømer, Erik Hasselager, Peder Lisby Nørby, Torben Steiniche, Jes Thorn Clausen and Knud Kragballe
J Invest Dermatol 121: 1306-1311; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12626.x
Botulinum Toxin Type B Blocks Sudomotor Function Effectively: A 6 Month Follow Up FREE
Frank Birklein, Gabi Eisenbarth, Frank Erbguth and Martin Winterholler
J Invest Dermatol 121: 1312-1316; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12620.x
See also: Editorial by ReesConnective Tissue
Collagen of Chronically Inflamed Skin Is Over-Modified and Upregulates Secretion of Matrix Metalloproteinase 2 and Matrix-Degrading Enzymes by Endothelial Cells and Fibroblasts FREE
Arisa Hirota, Tetsuya Ebihara, Masashi Kusubata, Miya Kobayashi, Kunihiko Kobayashi, Kumiko Kuwaba, Keisuke Tanaka, Tomomi Kiriyama, Shinkichi Irie and Yoh-ichi Koyama
J Invest Dermatol 121: 1317-1325; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12637.x
Keratinocytes Promote Proliferation and Inhibit Apoptosis of the Underlying Fibroblasts: An Important Role in the Pathogenesis of Keloid FREE
Emi Funayama, Thinle Chodon, Akihiko Oyama and Tsuneki Sugihara
J Invest Dermatol 121: 1326-1331; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12572.x
See also: Editorial by GoldsmithReversible Dissociation of Collagen in Tissues FREE
Alvin T Yeh, Bernard Choi, J Stuart Nelson and Bruce J Tromberg
J Invest Dermatol 121: 1332-1335; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12634.x
Genetics
Rapid Decay of 
6 Integrin Caused by a Mis-Sense Mutation in the Propeller Domain Results in Severe Junctional Epidermolysis Bullosa with Pyloric Atresia FREE
Maryline Allegra, Laurent Gagnoux-Palacios, Yannick Gache, Stéphanie Roques, Gilles Lestringant, Jean-Paul Ortonne and Guerrino Meneguzzi
J Invest Dermatol 121: 1336-1343; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12625.x
Identification of a Lethal Form of Epidermolysis Bullosa Simplex Associated with a Homozygous Genetic Mutation in Plectin FREE
Alexandra Charlesworth, Laurent Gagnoux-palacios, Maryse Bonduelle, Jean-Paul Ortonne, Linda De Raeve and Guerrino Meneguzzi
J Invest Dermatol 121: 1344-1348; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12639.x
Impaired Trafficking of the Desmoplakins in Cultured Darier's Disease Keratinocytes FREE
Jittima Dhitavat, Christian Cobbold, Natalie Leslie, Susan Burge and Alain Hovnanian
J Invest Dermatol 121: 1349-1355; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12557.x
A Novel Loss-of-Function Mutation (N48K) in the PTEN Gene in a Spanish Patient with Cowden Disease FREE
Ana Vega, Josema Torres, María Torres, José Cameselle-teijeiro, Manuel Macia, Ángel Carracedo and Rafael Pulido
J Invest Dermatol 121: 1356-1359; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12638.x
HCR, a Candidate Gene for Psoriasis, Is Expressed Differently in Psoriasis and Other Hyperproliferative Skin Disorders and Is Downregulated by Interferon-
in Keratinocytes FREE
Sari Suomela, Outi Elomaa, Kati Asumalahti, Arja Leena Kariniemi, Seija Liisa Karvonen, Juha Peltonen, Juha Kere and Ulpu Saarialho-Kere
J Invest Dermatol 121: 1360-1364; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12642.x
Immunology/Infection
T Cell Receptor Gene Usage in Desmoglein-3-Specific T Lymphocytes from Patients with Pemphigus Vulgaris FREE
Mary K Hacker-foegen, Janet A Fairley and Mong-Shang Lin
J Invest Dermatol 121: 1365-1372; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12601.x
Pathogenicity and Epitope Characteristics of Anti-Desmoglein-1 from Pemphigus Foliaceus Patients Expressing Only IgG1 Autoantibodies FREE
Mary K Hacker-foegen, Marleen Janson, Masayuki Amagai, Janet A Fairley and Mong-Shang Lin
J Invest Dermatol 121: 1373-1378; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12608.x
Interleukin-21 Inhibits Dendritic Cell-Mediated T Cell Activation and Induction of Contact Hypersensitivity In Vivo FREE
Katja Brandt, Silvia Bulfone-Paus, André Jenckel, Donald C Foster, Ralf Paus and René Rückert
J Invest Dermatol 121: 1379-1382; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12603.x
Dimethylfumarate Is a Potent Inducer of Apoptosis in Human T Cells FREE
Felix Treumer, Kejian Zhu, Regine Gläser and Ulrich Mrowietz
J Invest Dermatol 121: 1383-1388; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12605.x
Toll-Like Receptor Expression in Human Keratinocytes: Nuclear Factor 
B Controlled Gene Activation by Staphylococcus aureus is Toll-Like Receptor 2 But Not Toll-Like Receptor 4 or Platelet Activating Factor Receptor Dependent FREE
Martin Mempel, Verena Voelcker, Gabriele Köllisch, Christian Plank, Roland Rad, Markus Gerhard, Christina Schnopp, Peter Fraunberger, Autar K Walli, Johannes Ring, Dietrich Abeck and Markus Ollert
J Invest Dermatol 121: 1389-1396; doi:10.1111/j.1523-1747.2003.12630.x
Interleukin-3 in Cooperation with Transforming Growth Factor Induces Granulocyte Macrophage Colony Stimulating Factor Independent Differentiation of Human CD34+ Hematopoietic Progenitor Cells into Dendritic Cells with Features of Langerhans Cells FREE
Zia U A Mollah, Setsuya Aiba, Satoshi Nakagawa, Masato Mizuashi, Tomoyuki Ohtani, Yumiko Yoshino and Hachiro Tagami
J Invest Dermatol 121: 1397-1401; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12641.x
The Autoantigen of Anti-p200 Pemphigoid Is an Acidic Noncollagenous N-Linked Glycoprotein of the Cutaneous Basement Membrane FREE
Iakov Shimanovich, Yoshiaki Hirako, Cassian Sitaru, Takashi Hashimoto, Eva-B Bröcker, Elke Butt and Detlef Zillikens
J Invest Dermatol 121: 1402-1408; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12609.x
Immunopathologic Features of Allergic Contact Dermatitis in Humans: Participation of Plasmacytoid Dendritic Cells in the Pathogenesis of the Disease? FREE
Christine Bangert, Josef Friedl, Georg Stary, Georg Stingl and Tamara Kopp
J Invest Dermatol 121: 1409-1418; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12623.x
Mechanisms for a Novel Immune Evasion Strategy in the Scabies Mite Sarcoptes Scabiei: A Multigene Family of Inactivated Serine Proteases FREE
Deborah C Holt, Katja Fischer, George E Allen, Danny Wilson, Peter Wilson, Robert Slade, Bart J Currie, Shelley F Walton and David J Kemp
J Invest Dermatol 121: 1419-1424; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12621.x
Generation of a Large Number of Connective Tissue Type Mast Cells by Culture of Murine Fetal Skin Cells FREE
Nobuo Yamada, Hironori Matsushima, Yutaka Tagaya, Shinji Shimada and Stephen I Katz
J Invest Dermatol 121: 1425-1432; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12613.x
Keratinocytes/Epidermis
Tumor Necrosis Factor Related Apoptosis Inducing Ligand Triggers Apoptosis in Dividing but not in Differentiating Human Epidermal Keratinocytes FREE
Bastiaan J H Jansen, Fred van Ruissen, Stefanie Cerneus, Wendy Cloin, Mieke Bergers, Piet E J van Erp and Joost Schalkwijk
J Invest Dermatol 121: 1433-1439; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12636.x
The Organization of Human Epidermis: Functional Epidermal Units and Phi Proportionality FREE
Steven B Hoath and D G Leahy
J Invest Dermatol 121: 1440-1446; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12606.x
Modulation of Gene Expression Induced in Human Epidermis by Environmental Stress In Vivo FREE
Claire Marionnet, Françoise Bernerd, Arnaud Dumas, Franck Verrecchia, Karine Mollier, Delphine Compan, Bruno Bernard, Morad Lahfa, Jacques Leclaire, Chantal Medaisko, Bruno Mehul, Sophie Seité, Alain Mauviel and Louis Dubertret
J Invest Dermatol 121: 1447-1458; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12629.x
Transcriptional Profiling of Epidermal Keratinocytes: Comparison of Genes Expressed in Skin, Cultured Keratinocytes, and Reconstituted Epidermis, Using Large DNA Microarrays FREE
Alix Gazel, Patricia Ramphal, Martin Rosdy, Bart De wever, Carine Tornier, Nadia Hosein, Brian Lee, Marjana Tomic-Canic and Miroslav Blumenberg
J Invest Dermatol 121: 1459-1468; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12611.x
Transcriptional Control of the Mouse Col7a1 Gene in Keratinocytes: Basal and Transforming Growth Factor- Regulated Expression FREE
Michael Naso, Jouni Uitto and John F Klement
J Invest Dermatol 121: 1469-1478; doi:10.1111/j.1523-1747.2003.12640.x
Crucial Effects of Fibroblasts and Keratinocyte Growth Factor on Morphogenesis of Reconstituted Human Oral Epithelium FREE
Daniela Elena Costea, Lado Lako Loro, Elisabeth Anne Okumo Dimba, Olav Karsten Vintermyr and Anne Christine Johannessen
J Invest Dermatol 121: 1479-1486; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12616.x
Aquaporin 3 Colocates with Phospholipase D2 in Caveolin-Rich Membrane Microdomains and Is Downregulated Upon Keratinocyte Differentiation FREE
Xiangjian Zheng and Wendy Bollinger Bollag
J Invest Dermatol 121: 1487-1495; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12614.x
Corticotropin-Releasing Hormone Inhibits Nuclear Factor-B Pathway in Human HaCaT Keratinocytes FREE
Blazej Zbytek, Lawrence M Pfeffer and Andrzej T Slominski
J Invest Dermatol 121: 1496-1499; doi:10.1111/j.1523-1747.2003.12612.x
17-Estradiol Inhibits Oxidative Stress-Induced Apoptosis in Keratinocytes by Promoting Bcl-2 Expression FREE
Naoko Kanda and Shinichi Watanabe
J Invest Dermatol 121: 1500-1509; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12617.x
Melanocytes/Melanoma
p53 Codon 72 Arg Homozygotes Are Associated with an Increased Risk of Cutaneous Melanoma FREE
Hongbing Shen, Zhensheng Liu, Sara S Strom, Margaret R Spitz, Jeffrey E Lee, Jeffrey E Gershenwald, Merrick I Ross, Paul F Mansfield, Madeleine Duvic, Honnavara N Ananthaswamy and Qingyi Wei
J Invest Dermatol 121: 1510-1514; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12648.x
See also: Editorial by ReesNeurobiology
Expression and Function of Neurotrophins and Their Receptors in Cultured Human Keratinocytes FREE
A Marconi, M Terracina, C Fila, J Franchi, F Bonté, G Romagnoli, R Maurelli, C M Failla, M Dumas and C Pincelli
J Invest Dermatol 121: 1515-1521; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12624.x
Tumor Biology
Contribution of Flow Cytometry in the Diagnosis of Cutaneous Lymphoid Lesions FREE
Hong Wu, Mitchell Smith, Michael M Millenson, Nicos Nicolaou, Vivianna M Van Deerlin, Kathkali Addya, Stuart Lessin and Tahseen Al-saleem
J Invest Dermatol 121: 1522-1530; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12631.x
Presence of Human Papillomavirus DNA in Plucked Eyebrow Hairs Is Associated with a History of Cutaneous Squamous Cell Carcinoma FREE
Linda Struijk, Jan Nico Bouwes Bavinck, Patrick Wanningen, Els Van der meijden, Rudi G J Westendorp, Jan Ter schegget and Mariet C W Feltkamp
J Invest Dermatol 121: 1531-1535; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12632.x
See also: Editorial by ReesVascular Biology
An N-Terminal 80 kDa Recombinant Fragment of Human Thrombospondin-2 Inhibits Vascular Endothelial Growth Factor Induced Endothelial Cell Migration In Vitro and Tumor Growth and Angiogenesis In Vivo FREE
Yun-Hee Noh, Kant Matsuda, Young-Kwon Hong, Rainer Kunstfeld, Lucia Riccardi, Manuel Koch, Hajimu Oura, Soheil S Dadras, Michael Streit and Michael Detmar
J Invest Dermatol 121: 1536-1543; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12643.x
Wound Healing
Expression and Activity of Arginase Isoenzymes During Normal and Diabetes-Impaired Skin Repair FREE
Heiko Kämpfer, Josef Pfeilschifter and Stefan Frank
J Invest Dermatol 121: 1544-1551; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12610.x
Letters to the Editors
The Importance of Cationic Amino Acid Transporter Expression in Human Skin FREE
Kristin Recker, Thomas Klapperstück, Astrid Kehlen and Johannes Wohlrab
J Invest Dermatol 121: 1552-1553; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12646.x
The 97-kDa (LABD97) and 120-kDa (LAD-1) Fragments of Bullous Pemphigoid Antigen 180/Type XVII Collagen Have Different N-Termini FREE
Yoshiaki Hirako, Yuji Nishizawa, Cassian Sitaru, Annika Opitz, Katrin Marcus, Helmut E Meyer, Elke Butt, Katsushi Owaribe and Detlef Zillikens
J Invest Dermatol 121: 1554-1556; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12607.x
Altered Distribution of Calcium in Facial Epidermis of Aged Adults FREE
Mitsuhiro Denda, Akiko Tomitaka, Hirohiko Akamatsu and Kayoko Matsunaga
J Invest Dermatol 121: 1557-1558; doi:10.1111/j.1523-1747.2003.12619.x
Detection and Mutation Screening of malassezia sympodialis Sequences Coding for the Mal s 1 Allergen Implicated in Atopic Dermatitis FREE
George Gaitanis, Panayiotis Menounos, Andreas Katsambas and Aristea Velegraki
J Invest Dermatol 121: 1559-1560; advance online publication, December 8, 2003; doi:10.1046/j.1523-1747.2003.12618.x
Genetic Basis of Male Pattern Baldness FREE
Dale R Nyholt, Nathan A Gillespie, Andrew C Heath and Nicholas G Martin
J Invest Dermatol 121: 1561-1564; advance online publication, December 8, 2003; doi:10.1111/j.1523-1747.2003.12615.x
Erratum FREE
J Invest Dermatol 121: 1565; doi:10.1111/j.1523-1747.2003.12660.x
Abstracts of the Congrés Annuel de la Recherche Dermatologique (CARD) 12–13 June 2003, Rouen France FREE
J Invest Dermatol 121: 1566-1578; doi:10.1111/j.1523-1747.2003.12655.x
SID Acknowledgements 2002 FREE
J Invest Dermatol 121: 1579-1580; doi:10.1111/j.1523-1747.2003.12654.x
SID Minutes 2002 FREE
J Invest Dermatol 121: 1581-1584; doi:10.1111/j.1523-1747.2003.12653.x
