TABLE OF CONTENTS

Volume 121, Issue 5 (November 2003)

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Marion B. Sulzberger, M.d. 1895–1983; a Twenty Year Retrospective

Remembering Marion Sulzberger, 1895–1983 FREE

Lowell A Goldsmith

J Invest Dermatol 121: v-v; doi:10.1046/j.1523-1747.2003.12578_1.x

Marion B Sulzberger's Legacy, Or the Privilege of Learning: Remarks on Occasion of the 20th Anniversary of His Death—A Perspective from Abroad FREE

Karl Holubar

J Invest Dermatol 121: vi-vi; doi:10.1046/j.1523-1747.2003.12578_2.x

Sulzberger Lessons for the 21st Century FREE

Irwin M Freedberg

J Invest Dermatol 121: vii-viii; doi:10.1046/j.1523-1747.2003.12578_3.x

Journal of Investigative Dermatology, Volume 24 Festschrift in Honor of Marion B. Sulzberger's 60th Birthday FREE

J Invest Dermatol 121: ix-ix; doi:10.1111/j.1523-1747.2003.12587.x

Marion B. Sulzberger, M.d. 1895–1983; A Twenty Year Retrospective FREE

J Invest Dermatol 121: x-x; doi:10.1111/j.1523-1747.2003.12595.x

Festschrift FREE

J Invest Dermatol 121: xi-xi; doi:10.1111/j.1523-1747.2003.12588.x

Marion Sulzberger, Our Guide: Always looking to the Future FREE

J Invest Dermatol 121: xii-xii; doi:10.1111/j.1523-1747.2003.12586.x

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Editorials

Clinical Snippets FREE

Lowell A Goldsmith

J Invest Dermatol 121: xiii-xiii; doi:10.1046/j.1523-1747.2003.12580.x

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Commentaries

Activation of B-raf in Non-Malignant Nevi Predicts a Novel Tumor Suppressor Gene in Melanoma (MAP Kinase Phosphatase) FREE

Jack L Arbiser

J Invest Dermatol 121: xiv-xiv; doi:10.1046/j.1523-1747.2003.12583.x

See also: Original Article by Yazdi et al.

The Continuing Saga of Epidermal Stem Cells FREE

Jackie R Bickenbach

J Invest Dermatol 121: xv-xvi; doi:10.1046/j.1523-1747.2003.12577.x

See also: Original Article by Geer & Andreadis

Decreased Serum Ferritin and Alopecia in Women FREE

D Hugh Rushton

J Invest Dermatol 121: xvii-xviii; doi:10.1046/j.1523-1747.2003.12581.x

See also: Original Article by Kantor et al.

Matrix Metalloproteinase-19: What Role Does this Enzyme Play in Wound Healing? FREE

Cornelia Mauch

J Invest Dermatol 121: xix-xx; doi:10.1046/j.1523-1747.2003.12582.x

See also: Original Article by Hieta et al.

Fibrin Is a Many Splendored Thing FREE

Richard A F Clark, MD

J Invest Dermatol 121: xxi-xxii; doi:10.1046/j.1523-1747.2003.12575.x

See also: Original Article by Geer & Andreadis

Talk to the Hand 'Cause the Nucleus Ain't Listening: Adhesion, Communication, and Tumor Cell Invasion in the Skin  FREE

David S Rubenstein, MD, PhD

J Invest Dermatol 121: xxiii-xxiv; doi:10.1046/j.1523-1747.2003.12576.x

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Review Article

The Molecular Basis of Lymphocyte Recruitment to the Skin: Clues for Pathogenesis and Selective Therapies of Inflammatory Disorders FREE

Michael P Schön, Thomas M Zollner and W-Henning Boehncke

J Invest Dermatol 121: 951-962; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12563.x

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Original Articles

Appendages

Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge FREE

Yaping Liu, Stephen Lyle, Zaixin Yang and George Cotsarelis

J Invest Dermatol 121: 963-968; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12600.x

Profile of Transforming Growth Factor-beta Responses During the Murine Hair Cycle FREE

Tsutomu Soma, Cord E Dohrmann, Toshihiko Hibino and Laurel A Raftery

J Invest Dermatol 121: 969-975; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12516.x

Kit Is Expressed by Epithelial Cells In Vivo  FREE

Eva M J Peters, Marcus Maurer, Vladimir A Botchkarev, Karin deMasey Jensen, Pia Welker, Glynis A Scott and Ralf Paus

J Invest Dermatol 121: 976-984; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12478.x

Decreased Serum Ferritin is Associated With Alopecia in Women FREE

Jonathan Kantor, Lisa Jay Kessler, David G Brooks and George Cotsarelis

J Invest Dermatol 121: 985-988; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12540.x

See also: Commentary by Rushton

Connective Tissue

Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation FREE

Thorsten Sadowski, Sebastian Dietrich, Matthias Müller, Blanka Havlickova, Michael Schunck, Ehrhardt Proksch, Markus Stefan Müller and Radislav Sedlacek

J Invest Dermatol 121: 989-996; doi:10.1046/j.1523-1747.2003.12526.x

Matrix Metalloproteinase-19 Expression in Dermal Wounds and by Fibroblasts in Culture FREE

Niina Hieta, Ulla Impola, Carlos López-Otín, Ulpu Saarialho-Kere and Veli-Matti Kähäri

J Invest Dermatol 121: 997-1004; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12533.x

See also: Commentary by Mauch
Mechanisms of Hypoxic Regulation of Plasminogen Activator Inhibitor-1 Gene Expression in Keloid Fibroblasts FREE

Qunzhou Zhang, Yidi Wu, David K Ann, Diana V Messadi, Tai-Lan Tuan, A Paul Kelly, Charles N Bertolami and Anh D Le

J Invest Dermatol 121: 1005-1012; doi:10.1046/j.1523-1747.2003.12564.x

Genetics

Splice Site and Deletion Mutations in Keratin (KRT1 and KRT10) Genes: Unusual Phenotypic Alterations in Scandinavian Patients with Epidermolytic Hyperkeratosis FREE

Marie Virtanen, S Kaye Smith, Tobias Gedde-Dahl Jr, Anders Vahlquist and Paul E Bowden

J Invest Dermatol 121: 1013-1020; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12534.x

Normal and Gene-Corrected Dystrophic Epidermolysis Bullosa Fibroblasts Alone Can Produce Type VII Collagen at the Basement Membrane Zone FREE

David T Woodley, Gerald G Krueger, Cynthia M Jorgensen, Janet A Fairley, Tom Atha, Yi Huang, Lawrence Chan, Douglas R Keene and Mei Chen

J Invest Dermatol 121: 1021-1028; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12571.x

Truncation of CGI-58 Protein Causes Malformation of Lamellar Granules Resulting in Ichthyosis in Dorfman-Chanarin Syndrome FREE

Masashi Akiyama, Daisuke Sawamura, Yuko Nomura, Makoto Sugawara and Hiroshi Shimizu

J Invest Dermatol 121: 1029-1034; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12520.x

Clouston Syndrome Can Mimic Pachyonychia Congenita FREE

Maurice A M van Steensel, Marcel F Jonkman, Michel van Geel, Peter M Steijlen, W H Irwin McLean and Frances J D Smith

J Invest Dermatol 121: 1035-1038; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12527.x

Immunology/Infection

Thiol Antioxidants Block the Activation of Antigen-Presenting Cells by Contact Sensitizers FREE

Stefanie Bruchhausen, Sabine Zahn, Elke Valk, Jürgen Knop and Detlef Becker

J Invest Dermatol 121: 1039-1044; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12510.x

Chemokine Receptor Expression on Neoplastic and Reactive T Cells in the Skin at Different Stages of Mycosis Fungoides FREE

Tilmann Kallinich, J Marcus Muche, Shixin Qin, Wolfram Sterry, Heike Audring and Richard A Kroczek

J Invest Dermatol 121: 1045-1052; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12555.x

Sex Differences in Opioid-Induced Enhancement of Contact Hypersensitivity FREE

Jay C Elliott, Mitchell J Picker, Christina J Nelson, Kelly A Carrigan and Donald T Lysle

J Invest Dermatol 121: 1053-1059; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12569.x

Thalidomide Inhibits Tumor Necrosis Factor-alpha Production and Antigen Presentation by Langerhans Cells FREE

Liang Deng, Wanhong Ding and Richard D Granstein

J Invest Dermatol 121: 1060-1065; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12565.x

Keratinocyte ATP Release Assay for Testing Skin-Irritating Potentials of Structurally Diverse Chemicals FREE

Norikatsu Mizumoto, Mark E Mummert, David Shalhevet and Akira Takashima

J Invest Dermatol 121: 1066-1072; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12558.x

H1 and H2 Histamine Receptors Are Absent on Langerhans Cells and Present on Dermal Dendritic Cells FREE

Tomoyuki Ohtani, Setsuya Aiba, Masato Mizuashi, Zia UA Mollah, Satoshi Nakagawa and Hachiro Tagami

J Invest Dermatol 121: 1073-1079; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12570.x

Immune Protection Factors of Chemical Sunscreens Measured in the Local Contact Hypersensitivity Model in Humans FREE

Peter Wolf, Christine Hoffmann, Franz Quehenberger, Stephan Grinschgl and Helmut Kerl

J Invest Dermatol 121: 1080-1087; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12361.x

Keratinocytes/Epidermis

Inhibition of the Epidermal Growth Factor Receptor Suppresses Telomerase Activity in HSC-1 Human Cutaneous Squamous Cell Carcinoma Cells FREE

Arief Budiyanto, Toshinori Bito, Makoto Kunisada, Masashi Ashida, Masamitsu Ichihashi and Masato Ueda

J Invest Dermatol 121: 1088-1094; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12529.x

Side Population Keratinocytes Resembling Bone Marrow Side Population Stem Cells Are Distinct From Label-Retaining Keratinocyte Stem Cells FREE

Atsushi Terunuma, Kimberly L Jackson, Veena Kapoor, William G Telford and Jonathan C Vogel

J Invest Dermatol 121: 1095-1103; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12531.x

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor kappaB in Normal and Lesional Psoriatic Skin FREE

Majken Westergaard, Jeanette Henningsen, Claus Johansen, Sofie Rasmussen, Morten Lyhne Svendsen, Uffe Birk Jensen, Henrik Daa Schrøder, Bart Staels, Lars Iversen, Lars Bolund, Knud Kragballe and Karsten Kristiansen

J Invest Dermatol 121: 1104-1117; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12536.x

Lasers and Microdermabrasion Enhance and Control Topical Delivery of Vitamin C FREE

Woan-Ruoh Lee, Shing-Chuan Shen, Kuo-Hsien Wang, Chung-Hong Hu and Jia-You Fang

J Invest Dermatol 121: 1118-1125; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12537.x

Differential Regulation of Cyclooxygenase-2 Expression by Phytosphingosine Derivatives, NAPS and TAPS, and its Role in the NAPS or TAPS-Mediated Apoptosis FREE

Hye Jung Kim, Weonhye Shin, Chang Seo Park, Hyung-Ok Kim and Tae-Yoon Kim

J Invest Dermatol 121: 1126-1134; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12554.x

Tetraacetyl Phytosphingosine-Induced Caspase Activation and Apoptosis Occur Through G2 Arrest in Human Keratinocyte HaCaT Cells FREE

Ho Jin Kim, Hye Jung Kim, Sang Hoon Kim and Tae-Yoon Kim

J Invest Dermatol 121: 1135-1137; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12553.x

Iontophoresis and Sonophoresis Stimulate Epidermal Cytokine Expression at Energies That Do Not Provoke a Barrier Abnormality: Lamellar Body Secretion and Cytokine Expression Are Linked to Altered Epidermal Calcium Levels FREE

Eung Ho Choi, Min Jung Kim, Byung-Il Yeh, Sung Ku Ahn and Seung Hun Lee

J Invest Dermatol 121: 1138-1144; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12566.x

Purinergic Receptors Are Part of a Signaling System for Keratinocyte Proliferation, Differentiation, and Apoptosis in Human Fetal Epidermis FREE

Aina V H Greig, Claire Linge, Alison Cambrey and Geoffrey Burnstock

J Invest Dermatol 121: 1145-1149; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12567.x

Melanocytes/Melanoma

Human Melanoblasts in Culture: Expression of BRN2 and Synergistic Regulation by Fibroblast Growth Factor-2, Stem Cell Factor, and Endothelin-3 FREE

Anthony L Cook, Philippe D Donatien, Aaron G Smith, Mark Murphy, Malcolm K Jones, Meenhard Herlyn, Dorothy C Bennett, J Helen Leonard and Richard A Sturm

J Invest Dermatol 121: 1150-1159; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12562.x

Mutations of the BRAF Gene in Benign and Malignant Melanocytic Lesions FREE

Amir S Yazdi, Gabriele Palmedo, Michael J Flaig, Ursula Puchta, Andrea Reckwerth, Arno Rütten, Thomas Mentzel, Heino Hügel, Markus Hantschke, Monika-Hildegard Schmid-Wendtner, Heinz Kutzner and Christian A Sander

J Invest Dermatol 121: 1160-1162; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12559.x

See also: Commentary by Arbiser

Photobiology

Vitamin A Exerts a Photoprotective Action in Skin by Absorbing Ultraviolet B Radiation FREE

Christophe Antille, Christian Tran, Olivier Sorg, Pierre Carraux, Liliane Didierjean and Jean-Hilaire Saurat

J Invest Dermatol 121: 1163-1167; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12519.x

S100A8 Induction in Keratinocytes by Ultraviolet A Irradiation Is Dependent on Reactive Oxygen Intermediates FREE

Michele A Grimbaldeston, Carolyn L Geczy, Nicodemus Tedla, John J Finlay-Jones and Prue H Hart

J Invest Dermatol 121: 1168-1174; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12561.x

Mice With Genetically Determined High Susceptibility to Ultraviolet (UV)-Induced Immunosuppression Show Enhanced UV Carcinogenesis FREE

Frances P Noonan, H Konrad Muller, Thomas R Fears, Donna F Kusewitt, Tracy M Johnson and Edward C De Fabo

J Invest Dermatol 121: 1175-1181; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12560.x

Tumor Biology

Abrogation of E-Cadherin-Mediated Adhesion Induces Tumor Cell Invasion in Human Skin-Like Organotypic Culture FREE

Alexander Margulis, Frank Andriani, Norbert Fusenig, Koji Hashimoto, Yasushi Hanakawa and Jonathan A Garlick

J Invest Dermatol 121: 1182-1190; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12523.x

Vascular Biology

Induction of Interferon Regulatory Factor 1 Expression in Human Dermal Endothelial Cells by Interferon-bold gamma and Tumor Necrosis Factor-alpha Is Transcriptionally Regulated and Requires Iron FREE

Amy K Gira, Katherine A Casper, Kristen B Otto, Shubhada M Naik, S Wright Caughman and Robert A Swerlick

J Invest Dermatol 121: 1191-1196; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12535.x

Endurance Training Enhances Vasodilation Induced by Nitric Oxide in Human Skin FREE

Yann Boegli, Gerald Gremion, Sandrine Golay, Sandrine Kubli, Lucas Liaudet, Pierre-François Leyvraz, Bernard Waeber and François Feihl

J Invest Dermatol 121: 1197-1204; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12518.x

Topically Applied Imiquimod Inhibits Vascular Tumor Growth In Vivo  FREE

Robert Sidbury, Nicole Neuschler, Erin Neuschler, Ping Sun, Xiao-qi Wang, Richard Miller, Mark Tomai, Elena Puscasiu, Sajiv Gugneja and Amy S Paller

J Invest Dermatol 121: 1205-1209; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12521.x

Wound Healing

A Novel Role of Fibrin in Epidermal Healing: Plasminogen-Mediated Migration and Selective Detachment of Differentiated Keratinocytes FREE

David J Geer and Stelios T Andreadis

J Invest Dermatol 121: 1210-1216; advance online publication, October 31, 2003; doi:10.1046/j.1523-1747.2003.12512.x

See also: Commentary by Clark,See also: Commentary by Bickenbach
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Letters to the Editor

Phenotypic Diversity and Mutation Spectrum in Hypotrichosis with Juvenile Macular Dystrophy FREE

Margarita Indelman, Christian P Hamel, Reuven Bergman, Ken K Nischal, Dorothy Thompson, Marie-Odile Surget, Michal Ramon, Hatam Ganthos, Benjamin Miller, Gabriele Richard, Raziel Lurie, Rina Leibu, Isabelle Russell-Eggitt and Eli Sprecher

J Invest Dermatol 121: 1217-1220; doi:10.1046/j.1523-1747.2003.12550_1.x

CD34 in Human Hair Follicle FREE

Enrique Poblet MD and Francisco Jiménez MD

J Invest Dermatol 121: 1220; doi:10.1046/j.1523-1747.2003.12550_2.x

Response FREE

Carol S Trempus MS, Rebecca J Morris PhD, George Cotsarelis MD and Raymond W Tennant PhD

J Invest Dermatol 121: 1220-1221; doi:10.1046/j.1523-1747.2003.12550_3.x

A Novel GJB2 (Connexin 26) Mutation, F142L, in a Patient with Unusual Mucocutaneous Findings and Deafness FREE

Chester W Brown, Moise L Levy, Catherine M Flaitz, Barbara S Reid, Spiros Manolidis, Adelaide A Hebert, Matthew M Bender, Heidi A Heilstedt, Katie S Plunkett, Ping Fang, Benjamin B Roa, Pil Chung, Hsiao-Yuan Tang, Gabriele Richard and Raye L Alford

J Invest Dermatol 121: 1221-1223; doi:10.1046/j.1523-1747.2003.12550_4.x

Structure and Heterogeneity of the Human Gene for Epiplakin (EPPK1) FREE

Naoko Takeo, Wenqing Wang, Noritaka Matsuo, Hideaki Sumiyoshi, Hidekatsu Yoshioka and Sakuhei Fujiwara

J Invest Dermatol 121: 1224-1226; doi:10.1046/j.1523-1747.2003.12550_5.x

Propionibacterium acnes-Reactive T Helper-1 Cells in the Skin of Patients with Acne Vulgaris FREE

Paul E Mouser, Barbara S Baker, Edward D Seaton and Anthony C Chu

J Invest Dermatol 121: 1226-1228; doi:10.1046/j.1523-1747.2003.12550_6.x

Tightening Tight Junctions with Compression Therapy FREE

Birgit Kahle, Marco Idzko, Johannes Norgauer, Eberhard Rabe and Yared Herouy

J Invest Dermatol 121: 1228-1229; doi:10.1046/j.1523-1747.2003.12550_7.x

Inhibition of Vascular Cell Adhesion Molecule-1 Expression in Human Dermal Microvascular Endothelial Cells by Iron Chelators FREE

Thierry Simonart

J Invest Dermatol 121: 1229-1230; doi:10.1046/j.1523-1747.2003.12550_8.x

Errata FREE

J Invest Dermatol 121: 1231; doi:10.1046/j.1523-1747.2003.12592.x

8th International Workshop on Langerhans Cells Tokyo, Japan September 5–7, 2003 Congress Organization FREE

J Invest Dermatol 121: 1232-1252; doi:10.1046/j.1523-1747.2003.12509.x

International Symposium on Atopic Dermatitis Rome, Italy August 29–31, 2003 Organizing Committee A. Giannetti, G. Girolomoni, S. Seidenari FREE

J Invest Dermatol 121: 1253-1265; doi:10.1046/j.1523-1747.2003.12591.x

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