Clinical Snippets FREE

Lowell A Goldsmith

J Invest Dermatol 121: iv-iv; doi:10.1046/j.1523-1747.2003.12079.x

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Biologic Lessons from Mutations in the Kreb's Cycle Enzyme, Fumarate Hydratase FREE

John A McGrath

J Invest Dermatol 121: vii-vii; doi:10.1046/j.1523-1747.2003.12503.x

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Photo Protection Begins at the Cellular Level: Microparasols on the Job FREE

Glynis Scott MD

J Invest Dermatol 121: viii-viii; doi:10.1046/j.1523-1747.2003.12504.x

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Are Broad-Spectrum Sunscreens Necessary for Immunoprotection? FREE

Antony R Young

J Invest Dermatol 121: ix-x; doi:10.1046/j.1523-1747.2003.12507.x

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The Great Escape: Another Way for Melanoma to Leave Physiological Control? FREE

Keiran S M Smalley and Meenhard Herlyn

J Invest Dermatol 121: xi-xii; doi:10.1046/j.1523-1747.2003.12506.x

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Expression of Cyclooxygenase Isozymes During Morphogenesis and Cycling of Pelage Hair Follicles in Mouse Skin: Precocious Onset of the First Catagen Phase and Alopecia upon Cyclooxygenase-2 Overexpression FREE

Karin Müller-Decker, Christoph Leder, Melanie Neumann, Gitta Neufang, Christiane Bayerl, Jürgen Schweizer, Friedrich Marks and Gerhard Fürstenberger

J Invest Dermatol 121: 661-668; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12473.x

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Protease-Activated Receptor-1 (Thrombin Receptor) Is Expressed in Mesenchymal Portions of Human Hair Follicle FREE

T Anan, T Sonoda, Y Asada, S Kurata and S Takayasu

J Invest Dermatol 121: 669-673; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12490.x

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Alopecia in a Novel Mouse Model RCO3 Is Caused by mK6irs1 Deficiency FREE

T Peters, R Sedlmeier, H Büssow, F Runkel, G H Lüers, D Korthaus, H Fuchs, M Hrabé de Angelis, G Stumm, A P Russ, R M Porter, M Augustin and T Franz

J Invest Dermatol 121: 674-680; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12491.x

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Actin Reorganization Is Abnormal and Cellular ATP Is Decreased in Hailey-Hailey Keratinocytes FREE

Ida Aronchik, Martin J Behne, Laura Leypoldt, Debbie Crumrine, Ervin Epstein, Shigaku Ikeda, Masayuki Mizoguchi, Graham Bench, Tullio Pozzan and Theodora Mauro

J Invest Dermatol 121: 681-687; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12472.x

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Human Keratinocyte ATP2C1 Localizes to the Golgi and Controls Golgi Ca²⁺ Stores FREE

Martin J Behne, Chia-Ling Tu, Ida Aronchik, Ervin Epstein, Graham Bench, Daniel D Bikle, Tullio Pozzan and Theodora M Mauro

J Invest Dermatol 121: 688-694; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12528.x

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Fibroblast Migration on Fibronectin Requires Three Distinct Functional Domains FREE

Richard A F Clark, Jian-Qiang An, Doris Greiling, Azim Khan and Jean E Schwarzbauer

J Invest Dermatol 121: 695-705; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12484.x

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View of Normal Human Skin In Vivo as Observed Using Fluorescent Fiber-Optic Confocal Microscopic Imaging FREE

Lucinda D Swindle, Steven G Thomas, Michael Freeman and Peter M Delaney

J Invest Dermatol 121: 706-712; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12477.x

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Latency-Associated Peptide Prevents Skin Fibrosis in Murine Sclerodermatous Graft-Versus-Host Disease, a Model for Human Scleroderma FREE

Yan Zhang, Laura L McCormick and Anita C Gilliam

J Invest Dermatol 121: 713-719; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12517.x

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Targeted Inactivation of Murine Laminin 2-Chain Gene Recapitulates Human Junctional Epidermolysis Bullosa FREE

Xianmin Meng, John F Klement, Dominic A Leperi, David E Birk, Takako Sasaki, Rupert Timpl, Jouni Uitto and Leena Pulkkinen

J Invest Dermatol 121: 720-731; doi:10.1046/j.1523-1747.2003.12515.x

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A Novel Missense Mutation in CYLD in a Family with Brooke–Spiegler Syndrome FREE

Guofang Hu, Meltem Önder, Melissa Gill, Burhan Aksakal, Murat Öztas, M Ali Gürer and Jülide Tok Çelebi

J Invest Dermatol 121: 732-734; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12514.x

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Psoriasis Susceptibility Locus on 18p Revealed by Genome Scan in Finnish Families Not Associated with PSORS1 FREE

Kati Asumalahti, Tarja Laitinen, Päivi Lahermo, Sari Suomela, Raija Itkonen-Vatjus, Christer Jansen, Jaakko Karvonen, Seija-Liisa Karvonen, Timo Reunala, Erna Snellman, Tutta Uurasmaa, Ulpu Saarialho-Kere and Juha Kere

J Invest Dermatol 121: 735-740; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12483.x

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Germline Fumarate Hydratase Mutations in Families with Multiple Cutaneous and Uterine Leiomyomata FREE

Amalia Martinez-Mir, Benjamin Glaser, Gary S. Chuang, Liran Horev, Arie Waldman, Danielle E Engler, Derek Gordon, Lynda J Spelman, Ioannis Hatzibougias, Jack Green, Angela M Christiano and Abraham Zlotogorski

J Invest Dermatol 121: 741-744; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12499.x

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Efficient Induction of CD8 T-Associated Immune Protection by Vaccination with mRNA Transfected Dendritic Cells FREE

Shohreh Zarei, Jean-François Arrighi, Gioele Ongaro, Thomas Calzascia, Olivier Haller, Christophe Frossard, Vincent Piguet, Paul R Walker and Conrad Hauser

J Invest Dermatol 121: 745-750; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12492.x

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Association of Transcription-Coupled Repair but Not Global Genome Repair with Ultraviolet-B-Induced Langerhans Cell Depletion and Local Immunosuppression FREE

Wendy Kölgen, Harry van Steeg, Gijsbertus T J van der Horst, Jan H J Hoeijmakers, Willem A van Vloten, Frank R de Gruijl and Johan Garssen

J Invest Dermatol 121: 751-756; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12476.x

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Inhibition of IgE-Production by Peroxisome Proliferator-Activated Receptor Ligands FREE

Ralph Rühl, Anja Dahten, Florian J Schweigert, Udo Herz and Margitta Worm

J Invest Dermatol 121: 757-764; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12493.x

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Autoantibodies in Vitiligo Patients Recognize Multiple Domains of the Melanin-Concentrating Hormone Receptor FREE

Raju V S R K Gottumukkala, Elizabeth A Waterman, Laura M Herd, David J Gawkrodger, Philip F Watson, Anthony P Weetman and E Helen Kemp

J Invest Dermatol 121: 765-770; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12494.x

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17-Estradiol Enhances the Production of Nerve Growth Factor in THP-1-Derived Macrophages or Peripheral Blood Monocyte-Derived Macrophages FREE

Naoko Kanda and Shinichi Watanabe

J Invest Dermatol 121: 771-780; doi:10.1046/j.1523-1747.2003.12487.x

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The Expression of Vitamin D-Upregulated Protein 1 in Skin and its Interaction with Sciellin in Cultured Keratinocytes FREE

Marie-France Champliaud, Alain Viel and Howard P Baden

J Invest Dermatol 121: 781-785; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12539.x

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Vitamin C Recycling Is Enhanced in the Adaptive Response to Leptin-Induced Oxidative Stress in Keratinocytes FREE

Isabella Savini, Maria Valeria Catani, Antonello Rossi, Guglielmo Duranti, Marco Ranalli, Gerry Melino, Stefania Sabatini and Luciana Avigliano

J Invest Dermatol 121: 786-793; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12538.x

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The Characterization of Molecular Organization of Multilamellar Emulsions Containing Pseudoceramide and Type III Synthetic Ceramide FREE

B D Park, J K Youm, S K Jeong, E H Choi, S K Ahn and S H Lee

J Invest Dermatol 121: 794-801; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12470.x

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The Heregulin/Human Epidermal Growth Factor Receptor as a New Growth Factor System in Melanoma with Multiple Ways of Deregulation FREE

Christophe Stove, Veronique Stove, Lara Derycke, Veerle Van Marck, Marc Mareel and Marc Bracke

J Invest Dermatol 121: 802-812; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12522.x

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Role of Cytoplasmic Dynein in Perinuclear Aggregation of Phagocytosed Melanosomes and Supranuclear Melanin Cap Formation in Human Keratinocytes FREE

H Randolph Byers, Soniya Maheshwary, Dana M Amodeo and Sarah G Dykstra

J Invest Dermatol 121: 813-820; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12481.x

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A Novel Splice Variant of Pmel17 Expressed by Human Melanocytes and Melanoma Cells Lacking Some of the Internal Repeats FREE

Sarah E Nichols, Dawn C Harper, Joanne F Berson and Michael S Marks

J Invest Dermatol 121: 821-830; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12474.x

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Microphthalmia Associated Transcription Factor Is a Target of the Phosphatidylinositol-3-Kinase Pathway FREE

Mehdi Khaled, Lionel Larribere, Karine Bille, Jean-Paul Ortonne, Robert Ballotti and Corine Bertolotto

J Invest Dermatol 121: 831-836; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12420.x

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Ultraviolet Irradiation Induces Apoptosis in Human Immature, But Not in Skin Mast Cells FREE

Sven Guhl, Karin Hartmann, Silke Tapkenhinrichs, Alina Smorodchenko, Andreas Grützkau, Beate M Henz and Torsten Zuberbier

J Invest Dermatol 121: 837-844; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12480.x

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Ultraviolet B Radiation-Mediated Inhibition of Interferon--Induced Keratinocyte Activation Is Independent of Interleukin-10 and Other Soluble Mediators But Associated with Enhanced Intracellular Suppressors of Cytokine-Signaling Expression FREE

Markus Friedrich, Ruth Holzmann, Wolfram Sterry, Kerstin Wolk, Andreas Truppel, Helmut Piazena, Christiane Schonbein, Robert Sabat and Khusru Asadullah

J Invest Dermatol 121: 845-852; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12482.x

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Epidermal COX-2 Induction Following Ultraviolet Irradiation: Suggested Mechanism for the Role of COX-2 Inhibition in Photoprotection FREE

Catherine S Tripp, Eric A G Blomme, Kevin S Chinn, Medora M Hardy, Peter LaCelle and Alice P Pentland

J Invest Dermatol 121: 853-861; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12495.x

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Sunscreens Inadequately Protect Against Ultraviolet-A-Induced Free Radicals in Skin: Implications for Skin Aging and Melanoma? FREE

Rachel Haywood, Peter Wardman, Roy Sanders and Claire Linge

J Invest Dermatol 121: 862-868; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12498.x

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High Ultraviolet A Protection Affords Greater Immune Protection Confirming that Ultraviolet A Contributes to Photoimmunosuppression in Humans FREE

Elma D Baron, Anny Fourtanier, Delphine Compan, Chantal Medaisko, Kevin D Cooper and Seth R Stevens

J Invest Dermatol 121: 869-875; doi:10.1046/j.1523-1747.2003.12485.x

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DNA Mismatch Repair Protein Msh6 Is Required for Optimal Levels of Ultraviolet-B-Induced Apoptosis in Primary Mouse Fibroblasts FREE

Leah C Young, Anthea C Peters, Tomoko Maeda, Winfried Edelmann, Raju Kucherlapati, Susan E Andrew and Victor A Tron

J Invest Dermatol 121: 876-880; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12486.x

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Arsenic Trioxide Induces Apoptosis of Cutaneous T Cell Lymphoma Cells: Evidence for a Partially Caspase-Independent Pathway and Potentiation by Ascorbic Acid (Vitamin C) FREE

Laurence Michel, Alain Dupuy, Francette Jean-Louis, Aurore Sors, Joël Poupon, Manuelle Viguier, Philippe Musette, Louis Dubertret, Laurent Degos, Hervé Dombret and Hervé Bachelez

J Invest Dermatol 121: 881-893; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12479.x

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Microsatellite Instability Is Associated with Hypermethylation of the hMLH1 Gene and Reduced Gene Expression in Mycosis Fungoides FREE

Julia J Scarisbrick, Tracey J Mitchell, Eduardo Calonje, Guy Orchard, Robin Russell-Jones and Sean J Whittaker

J Invest Dermatol 121: 894-901; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12496.x

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Tazarotene-Induced Gene 3 Is Suppressed in Basal Cell Carcinomas and Reversed In Vivo by Tazarotene Application FREE

Madeleine Duvic, Xiao Ni, Rakhashandra Talpur, Kelly Herne, Claudia Schulz, Dawen Sui, Staci Ward, Aaron Joseph and Parul Hazarika

J Invest Dermatol 121: 902-909; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12488.x

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Release of Vascular Endothelial Growth Factor from a Human Melanoma Cell Line, WM35, Is Induced by Hypoxia but Not Ultraviolet Radiation and Is Potentiated by Activated Ras Mutation FREE

Yiqun G Shellman, Young-Lip Park, David G Marr, Katie Casper, Yisheng Xu, Mayumi Fujita, Robert Swerlick and David A Norris

J Invest Dermatol 121: 910-917; doi:10.1046/j.1523-1747.2003.12511.x

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Iron and 8-Isoprostane Levels in Acute and Chronic Wounds FREE

Sim Yeoh-Ellerton and Michael C Stacey

J Invest Dermatol 121: 918-925; doi:10.1046/j.1523-1747.2003.12471.x

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Selective Expression of Chemokine Monokine Induced by Interferon- in Alopecia Areata FREE

Sandrine Benoit, Atiye Toksoy, Matthias Goebeler and Reinhard Gillitzer

J Invest Dermatol 121: 933-935; doi:10.1046/j.1523-1747.2003.12524.x

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Activated Neutrophils Exert Antitumor Activity Against Human Melanoma Cells: Reactive Oxygen Species-Induced Mechanisms and Their Modulation by Granulocyte-Macrophage–Colony-Stimulating Factor FREE

Joachim Dissemond, Tatjana K Weimann, Lars A Schneider, Achim Schneeberger, Karin Scharffetter-Kochanek, Manfred Goos and Stephan N Wagner

J Invest Dermatol 121: 936-938; advance online publication, September 25, 2003; doi:10.1046/j.1523-1747.2003.12475.x

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