Journal of Investigative Dermatology

TABLE II

FROM:

The Increased Risk of Skin Cancer Is Persistent After Discontinuation of Psoralen+Ultraviolet A: A Cohort Study

Tamar E C Nijsten and Robert S Stern

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Table II. The number of person-years of exposure to each level for each variable and the distribution of patient's characteristics at final follow up in the PUVA Follow-Up Study

 No. of person-years (%) (n=27,840)No. of persons at last follow-up (%) (n=1380)
Age (y)  
 < 458856 (31.8%)129 (9.3%)
 45–6412,135 (43.6%)565 (40.9%)
 >646849 (24.6%)686 (49.7%)
Mena 17,602 (63.2%)892 (64.6%)
Skin typea   
 I–II7983 (28.7%)402 (29.1%)
 III–VI19,857 (71.3%)978 (70.9%)
Regiona   
 North15,846 (56.9%)781 (56.6%)
 Middle4960 (17.8%)233 (16.9%)
 South7034 (25.3%)364 (26.4%)
Methotrexate exposure  
 Low23,020 (82.7%)1039 (75.3%)
 Highb 4820 (17.3%)341 (24.7%)
Tar and/or UVB exposure  
 Low19,969 (71.7%)877 (63.6%)
 Highc 7871 (28.3%)503 (36.5%)
X-ray therapy prior to entering study  
 No21,230 (75.3%)1053 (76.3%)
 Yes6516 (23.4%)327 (23.7%)
No. of PUVA treatments  
 <10012,469 (44.8%)497 (36.0%)
 100–1997753 (27.9%)371 (26.9%)
 200–2993838 (13.8%)218 (15.8%)
 300–3991831 (6.6%)121 (8.8%)
 400–499918 (3.3%)70 (5.1%)
 greater than or equal to5001031 (3.7%)103 (7.5%)
Years since stopping PUVA  
 <211,296 (40.6%)85 (6.2%)
 2–55818 (20.9%)235 (17.0%)
 6–104898 (17.6%)324 (23.5%)
 11–153256 (11.7%)268 (19.4%)
 >152572 (9.2%)468 (33.9%)

a No. of persons presents the distribution at time of enrollment.

b High methotrexate exposure is greater than or equal to36 mo of therapy.

c High tar is greater than or equal to45 mo of therapy and high UVB exposure is greater than or equal to300 treatments.

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