TABLE OF CONTENTS

Volume 120, Issue 4 (April 2003)

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Editorials

Clinical Snippets FREE

Lowell A Goldsmith

J Invest Dermatol 120: vii-vii; doi:10.1038/jid.2003.5

In This Issue: Progress Towards A More Complete Understanding of Two Important Immune Diseases Involving Skin FREE

Mark C Udey

J Invest Dermatol 120: viii-viii; doi:10.1046/j.1523-1747.2003.12115.x

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Commentaries

Greater Diversity of Desmosomal Cadherins FREE

Ken Ishii

J Invest Dermatol 120: ix-x; doi:10.1046/j.1523-1747.2003.12110.x

See also: Original Article by Whittock & Bower

The Virtue of Tolerance FREE

Jonathan Vogel

J Invest Dermatol 120: xi-xii; doi:10.1046/j.1523-1747.2003.12118.x

See also: Original Article by Ohyama et al.

Paradoxical Effects of Sphingosine-1-Phosphate FREE

Wendy B Bollag

J Invest Dermatol 120: xiii-xiv; doi:10.1046/j.1523-1747.2003.12116.x

See also: Original Article by Vogler et al.

Caveolins in Epidermal Lamellar Bodies: Skin Is an Interactive Interface, Not an Inflexible Barrier FREE

Gopinathan K Menon

J Invest Dermatol 120: xv-xvi; doi:10.1046/j.1523-1747.2003.12117.x

See also: Original Article by Sando et al.

Genotyping Psoriasis FREE

Enno Christophers

J Invest Dermatol 120: xvii-xvii; doi:10.1046/j.1523-1747.2003.12111.x

See also: Original Article by Asumalahti et al.
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Original Articles

Appendages

Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 FREE

Carol S Trempus, Rebecca J Morris, Carl D Bortner, George Cotsarelis, Randall S Faircloth, Jeffrey M Reece and Raymond W Tennant

J Invest Dermatol 120: 501-511; doi:10.1046/j.1523-1747.2003.12088.x

K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle  FREE

Lutz Langbein, Michael A Rogers, Silke Praetzel, Hermelita Winter and Jürgen Schweizer

J Invest Dermatol 120: 512-522; doi:10.1046/j.1523-1747.2003.12087.x

Cell Biology

Genetic Evidence for a Novel Human Desmosomal Cadherin, Desmoglein 4 FREE

Neil V Whittock and Christopher Bower

J Invest Dermatol 120: 523-530; doi:10.1046/j.1523-1747.2003.12113.x

See also: Commentary by Ishii
Caveolin Expression and Localization in Human Keratinocytes Suggest a Role in Lamellar Granule Biogenesis FREE

G N Sando, H Zhu, J M Weis, J T Richman, P W Wertz and K C Madison

J Invest Dermatol 120: 531-541; doi:10.1046/j.1523-1747.2003.12051.x

See also: Commentary by Menon

Clinical Research

Function Blocking Autoantibodies Against Matrix Metalloproteinase-1 in Patients with Systemic Sclerosis FREE

Shinichi Sato, Ikuko Hayakawa, Minoru Hasegawa, Manabu Fujimoto and Kazuhiko Takehara

J Invest Dermatol 120: 542-547; doi:10.1046/j.1523-1747.2003.12097.x

Effect of Smoking and Sun on the Aging Skin FREE

Cornelis Kennedy, Maarten T Bastiaens, Chris D Bajdik, Rein Willemze, Rudi G J Westendorp and Jan N Bouwes Bavinck for the members of the Leiden Skin Cancer Study

J Invest Dermatol 120: 548-554; doi:10.1046/j.1523-1747.2003.12092.x

Keratinocytes/Epidermis

A Cryotransmission Electron Microscopy Study of Skin Barrier Formation FREE

Lars Norlén, Ashraf Al-Amoudi and Jaques Dubochet

J Invest Dermatol 120: 555-560; doi:10.1046/j.1523-1747.2003.12102.x

1alpha,25-Dihydroxyvitamin D3 Stimulates Activator Protein 1 DNA-Binding Activity by a Phosphatidylinositol 3-Kinase/Ras/MEK/Extracellular Signal Regulated Kinase 1/2 and c-Jun N-Terminal Kinase 1-Dependent Increase in c-Fos, Fra1, and c-Jun Expression in Human Keratinocytes FREE

Claus Johansen, Knud Kragballe, Jeanette Henningsen, Majken Westergaard, Karsten Kristiansen and Lars Iversen

J Invest Dermatol 120: 561-570; doi:10.1046/j.1523-1747.2003.12095.x

Suppressor of Cytokine Signaling 1/JAB and Suppressor of Cytokine Signaling 3/Cytokine-Inducible SH2 Containing Protein 3 Negatively Regulate the Signal Transducers and Activators of Transcription Signaling Pathway in Normal Human Epidermal Keratinocytes FREE

Kenshi Yamasaki, Yasushi Hanakawa, Sho Tokumaru, Yuji Shirakata, Koji Sayama, Toshikatsu Hanada, Akihiko Yoshimura and Koji Hashimoto

J Invest Dermatol 120: 571-580; doi:10.1046/j.1523-1747.2003.12100.x

New Acylceramide in Native and Reconstructed Epidermis FREE

Maria Ponec, Arij Weerheim, Peter Lankhorst and Phil Wertz

J Invest Dermatol 120: 581-588; doi:10.1046/j.1523-1747.2003.12103.x

Bovine-Serum-Albumin-Containing Receptor Phase Better Predicts Transdermal Absorption Parameters for Lipophilic Compounds FREE

Sheree E Cross, Yuri G Anissimov, Beatrice M Magnusson and Michael S Roberts

J Invest Dermatol 120: 589-591; doi:10.1046/j.1523-1747.2003.12083.x

Analysis of Proteins with Caseinolytic Activity in a Human Stratum Corneum Extract Revealed a Yet Unidentified Cysteine Protease and Identified the So-Called "Stratum Corneum Thiol Protease" as Cathepsin L2 FREE

D Bernard, B Méhul, A Thomas-Collignon, L Simonetti, V Remy, M A Bernard and R Schmidt

J Invest Dermatol 120: 592-600; doi:10.1046/j.1523-1747.2003.12086.x

Genetics

Genetic Heterogeneity in Erythrokeratodermia Variabilis: Novel Mutations in the Connexin Gene GJB4 (Cx30.3) and Genotype-Phenotype Correlations FREE

Gabriele Richard, Nkecha Brown, Fatima Rouan, Jan-Gerrit Van der Schroeff, Emilia Bijlsma, Lawrence F Eichenfield, Virginia P Sybert, Kenneth E Greer, Peter Hogan, Carmen Campanelli, John G Compton, Sherri J Bale, John J DiGiovanna and Jouni Uitto

J Invest Dermatol 120: 601-609; doi:10.1046/j.1523-1747.2003.12080.x

Suppression of the Immune Response Against Exogenous Desmoglein 3 in Desmoglein 3 Knockout Mice: An Implication for Gene Therapy FREE

Manabu Ohyama, Takayuki Ota, Miyo Aoki, Kazuyuki Tsunoda, Reiko Harada, Shigeo Koyasu, Takeji Nishikawa and Masayuki Amagai

J Invest Dermatol 120: 610-615; doi:10.1046/j.1523-1747.2003.12090.x

See also: Commentary by Vogel
Association of TAP and HLA-DM Genes with Psoriasis in Koreans FREE

Chul-Woo Pyo, Seong-Suk Hur, Yang-Kyum Kim, Tae-Yoon Kim and Tai-Gyu Kim

J Invest Dermatol 120: 616-622; doi:10.1046/j.1523-1747.2003.12091.x

Epidermolytic Hyperkeratosis and Epidermolysis Bullosa Simplex Caused by Frameshift Mutations Altering the V2 Tail Domains of Keratin 1 and Keratin 5 FREE

Eli Sprecher, Gil Yosipovitch, Reuven Bergman, Dan Ciubutaro, Margarita Indelman, Ellen Pfendner, Leok C Goh, Christopher J Miller, Jouni Uitto and Gabriele Richard

J Invest Dermatol 120: 623-626; doi:10.1046/j.1523-1747.2003.12084.x

Genetic Analysis of PSORS1 Distinguishes Guttate Psoriasis and Palmoplantar Pustulosis FREE

Kati Asumalahti, Mahreen Ameen, Sari Suomela, Eva Hagforsen, Gerd Michaëlsson, Julie Evans, Margo Munro, Colin Veal, Michael Allen, Joyce Leman, A David Burden, Brian Kirby, Maureen Connolly, Christopher E M Griffiths, Richard C Trembath, Juha Kere, Ulpu Saarialho-Kere and Jonathan NWN Barker

J Invest Dermatol 120: 627-632; doi:10.1046/j.1523-1747.2003.12094.x

See also: Commentary by Christophers

Immunology/Infection

Epicutaneous Natural Rubber Latex Sensitization Induces T Helper 2-Type Dermatitis and Strong Prohevein-Specific IgE Response FREE

Maili Lehto, Minna Koivuluhta, Guoying Wang, Iman Amghaiab, Marja-Leena Majuri, Kai Savolainen, Kristiina Turjanmaa, Henrik Wolff, Timo Reunala, Antti Lauerma, Timo Palosuo and Harri Alenius

J Invest Dermatol 120: 633-640; doi:10.1046/j.1523-1747.2003.12104.x

Afferent and Efferent Phases of Allergic Contact Dermatitis (ACD) Can Be Induced After a Single Skin Contact with Haptens: Evidence Using a Mouse Model of Primary ACD FREE

P Saint-Mezard, M Krasteva, C Chavagnac, S Bosset, H Akiba, J Kehren, J Kanitakis, D Kaiserlian, J F Nicolas and F Berard

J Invest Dermatol 120: 641-647; doi:10.1046/j.1523-1747.2003.12093.x

Melanocytes/Melanoma

Radiosensitization of Human Melanoma Cells by Ribozyme-Mediated Inhibition of Survivin Expression FREE

Marzia Pennati, Mara Binda, Gennaro Colella, Marco Folini, Lorenzo Citti, Raffaella Villa, Maria Grazia Daidone and Nadia Zaffaroni

J Invest Dermatol 120: 648-654; doi:10.1046/j.1523-1747.2003.12082.x

Photobiology

Influence of Hydration on Dihydroxyacetone-Induced Pigmentation of Stratum Corneum FREE

Bach-Cuc Nguyen and Irene E Kochevar

J Invest Dermatol 120: 655-661; doi:10.1046/j.1523-1747.2003.12089.x

De Novo Ceramide Synthesis Participates in the Ultraviolet B Irradiation-Induced Apoptosis in Undifferentiated Cultured Human Keratinocytes FREE

Yoshikazu Uchida, Anna Di Nardo, Vanessa Collins, Peter M Elias and Walter M Holleran

J Invest Dermatol 120: 662-669; doi:10.1046/j.1523-1747.2003.12098.x

Tumor Biology

T Cell Receptor-bold gamma Gene Analysis of CD30+ Large Atypical Individual Cells in CD30+ Large Primary Cutaneous T Cell Lymphomas FREE

Sylke Gellrich, Anke Wilks, Ansgar Lukowsky, Martin Wernicke, Astrid Müller, J Marcus Muche, Tanja Fischer, Kim Christian Jasch, Heike Audring and Wolfram Sterry

J Invest Dermatol 120: 670-675; doi:10.1046/j.1523-1747.2003.12101.x

High Frequency of Ultraviolet Mutations at the INK4a-ARF Locus in Squamous Cell Carcinomas from Psoralen-Plus-Ultraviolet-A-Treated Psoriasis Patients FREE

Heidemarie Kreimer-Erlacher, Hannes Seidl, Barbara Bäck, Lorenzo Cerroni, Helmut Kerl and Peter Wolf

J Invest Dermatol 120: 676-682; doi:10.1046/j.1523-1747.2003.12085.x

Vascular Biology

Stroma Formation and Angiogenesis by Overexpression of Growth Factors, Cytokines, and Proteolytic Enzymes in Human Skin Grafted to SCID Mice FREE

Claus J Gruss, Kapaettu Satyamoorthy, Carola Berking, John Lininger, Mark Nesbit, Helmut Schaider, Zhao-June Liu, Masahiro Oka, Mei-Yu Hsu, Takashi Shirakawa, Gang Li, Thomas Bogenrieder, Peter Carmeliet, Wafik S El-Deiry, Stephen L Eck, Justi S Rao, Andrew H Baker, Jean T Bennet, Timothy M Crombleholme, Omaida Velazquez, Jagajan Karmacharya, David J Margolis, James M Wilson, Michael Detmar, Mihaela Skobe, Paul D Robbins, Clayton Buck and Meenhard Herlyn

J Invest Dermatol 120: 683-692; doi:10.1046/j.1523-1747.2003.12112.x

Wound Healing

Sphingosine-1-Phosphate and Its Potentially Paradoxical Effects on Critical Parameters of Cutaneous Wound Healing FREE

Rüdiger Vogler, Bettina Sauer, Dong-Seok Kim, Monika Schäfer-Korting and Burkhard Kleuser

J Invest Dermatol 120: 693-700; doi:10.1046/j.1523-1747.2003.12096.x

See also: Commentary by Bollag
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Letters to the Editor

Autoantibody in Mucous Membrane Pemphigoid Binds to an Intracellular Epitope on Human beta4 Integrin and Causes Basement Membrane Zone Separation in Oral Mucosa in an Organ Culture Model FREE

K C Bhol, J E Colon and A R Ahmed

J Invest Dermatol 120: 701-702; doi:10.1046/j.1523-1747.2003.12081.x

The Crucial Role of TGF-beta in the Age-Related Alterations Induced by Ultrviolet A Irradiation FREE

Lei Yin, Akimichi Morita and Takuo Tsuji

J Invest Dermatol 120: 703-705; doi:10.1046/j.1523-1747.2003.12099.x

See also: Editorial by Goldsmith

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