Journal of Investigative Dermatology

FIGURE 4

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Analysis of Proteins with Caseinolytic Activity in a Human Stratum Corneum Extract Revealed a Yet Unidentified Cysteine Protease and Identified the So-Called "Stratum Corneum Thiol Protease" as Cathepsin L2

D Bernard, B Méhul, A Thomas-Collignon, L Simonetti, V Remy, M A Bernard and R Schmidt

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Figure 4.

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Comparison of SCTP (gelatinase) and group D cysteine-dependent protease activity after gel filtration chromatography. Human SC extract separated by gel filtration chromatography was analyzed for its cysteine-dependent activity. The activity detected on the gelatin zymogram (SCTP) did not correlate with the caseinolytic dependent activity (group D).

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