Journal of Investigative Dermatology

TABLE 1

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A Newly Identified Patient with Clinical Xeroderma Pigmentosum Phenotype has a Non-Sense Mutation in the DDB2 Gene and Incomplete Repair in (6-4) Photoproducts

Toshiki Itoh, Toshio Mori, Hiroaki Ohkubo and Masaru Yamaizumi

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Table 1. DNA repair levels in vivo in Ops1 cells

Cell straina Grains/nucleusRange of relative rate (%)b
UDS
 Ops1/Moric 14.4 plusminus 0.3/13.9 plusminus 0.399–108
 Ops1/Turuc 12.8 plusminus 0.3/ 9.8 plusminus 0.3124–138
 Ops1/Sonoc 8.9 plusminus 0.2/ 8.3 plusminus 0.2102–112
RRS
 Ops1/Morid 48.6 plusminus 3.9/40.2 plusminus 3.9101–145
 With caffeineWithout caffeineWith caffeineWithout caffeine
RDS59.9 plusminus 6.4/66.1 plusminus 5.972.2 plusminus 4.2/62.0 plusminus 5.974–110100–136
 Ops1/Morid     

a Mori, Turo, and Sono are normal control cells.

b Range of relative rate are the values (grain-numbers) of Ops1 cells compared with those of normal cells.

c The values represent the means plusminus SEM of 300 nuclei per cell strain in each coverslip. These were examined under the same conditions.

d The values represent the means plusminus SEM of 50 nuclei per cell strain.

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