FIGURE 2
FROM:
Animal Model of Sclerotic Skin. I: Local Injections of Bleomycin Induce Sclerotic Skin Mimicking Scleroderma
Toshiyuki Yamamoto, Shinsuke Takagawa, Ichiro Katayama, Kenshi Yamazaki, Yoichiro Hamazaki, Hiroshi Shinkai and Kiyoshi Nishioka
BACK TO ARTICLEFigure 2.

Dermal thickness in BALB/C mice treated with bleomycin. Mice were injected with 1 mg BLM per ml (dose per day, n = 6) (U25CF;) or PBS alone (n = 5) (
). Dermal thickness gradually increased as the sclerosis developed, whereas PBS-treated mice did not exhibit an increase of dermal thickness. Significant differences were noted after 3 wk. * p < 0.05.
