Journal of Cerebral Blood Flow & Metabolism

FIGURE 1

FROM:

Identification of early markers for symptomatic vasospasm in human cerebral microdialysate after subarachnoid hemorrhage: Preliminary results of a proteome-wide screening

Martin H Maurer, Daniel Haux, Oliver W Sakowitz, Andreas W Unterberg and Wolfgang Kuschinsky

BACK TO ARTICLE

Figure 1.

Figure and tables index
Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

(A) Examples of original two-dimensional electropherograms of human brain microdialysate for an asymptomatic SAH patient (upper panel) and a patient with symptomatic vasospasm (lower panel). Differentially expressed protein groups identified by cluster analysis are indicated (arrows) and marked for HSP7C and GAPDH. It is evident that GAPDH is higher and HSP7C is lower in the vasospastic patient than in the nonvasospastic patient. (B) Heat map of the hierarchical cluster analysis of all proteomic profiles. We used the clustering algorithm EPCLUST (http://ep.ebi.ac.uk) to sort the individual spots according to their expression profile. Red color codes for increased spot volume in symptomatic vasospasm patients, green for increased concentration in nonvasospastic controls. Clusters are marked for HSP7C and GAPDH. The spot isoforms for GAPDH and HSP7C were sorted into the same expression profile cluster, respectively.

Figure and tables index
BACK TO ARTICLE