TABLE 2

FROM:

Measurement of regional rates of cerebral protein synthesis with L-[1-¹¹C]leucine and PET with correction for recycling of tissue amino acids: II. Validation in rhesus monkeys

Carolyn Beebe Smith, Kathleen C Schmidt, Mei Qin, Thomas V Burlin, Michelle P Cook, Julia Kang, Richard C Saunders, John D Bacher, Richard E Carson, Michael A Channing, William C Eckelman, Peter Herscovitch, Peter Laverman and Bik-Kee Vuong

Table 2. rCPS (nmol g^-1 min^-1) in adult rhesus monkeys determined with L-[1-¹¹C]leucine PET: comparison of computation methods A and B

	Computed by method 'A'			Computed by method 'B'
	Animal A	Animal B	Animal C	Animal A	Animal B	Animal C
Whole brain	2.50.2	2.60.2	2.7	2.70.2	2.70.3	3.2
Somatosensory cortex	2.60.3	2.60.4	2.9	2.70.3	2.70.3	3.4
Primary visual cortex	3.10.2	3.00.3	3.1	3.30.2	3.20.4	3.7
Putamen	2.20.1	2.10.2	2.5	2.30.2	2.20.2	2.9
Cerebellum	2.50.2	2.60.2	2.8	2.70.2	2.80.2	3.3
Corona radiata	1.40.6	1.80.3	2.4	1.50.7	1.90.3	2.8
Internal/External capsule	1.60.1	1.60.3	2.1	1.70.1	1.70.3	2.5

 Animals A and B were studied four times and values of rCPS are the meanss.d. of four PET studies. Animal C was studied only one time.

 Regional values of the rate constants and were determined in each study from dynamic scan data and used to compute rCPS by means of equation (3) for method 'A' and equation (4) for method 'B'.