TABLE 1

FROM:

Measurement of regional rates of cerebral protein synthesis with L-[1-¹¹C]leucine and PET with correction for recycling of tissue amino acids: II. Validation in rhesus monkeys

Carolyn Beebe Smith, Kathleen C Schmidt, Mei Qin, Thomas V Burlin, Michelle P Cook, Julia Kang, Richard C Saunders, John D Bacher, Richard E Carson, Michael A Channing, William C Eckelman, Peter Herscovitch, Peter Laverman and Bik-Kee Vuong

Table 1. Parameter estimates in whole brain and brain regions

	K1 (mL g-1 min-1)	k2+k3 (min-1)	k4 (min-1)		Vb (ml/g)	Leucine T1/2 (min)
Whole brain	0.0400.003	0.0910.008	0.0360.005	0.720.01	0.0500.013	5.60.6
Somatosensory cortex	0.0400.004	0.0800.005	0.0320.005	0.720.01	0.0480.011	6.40.6
Primary visual cortex	0.0470.005	0.1060.019	0.0410.007	0.720.02	0.0490.012	4.90.9
Putamen	0.0450.003	0.0920.010	0.0270.004	0.770.02	0.0490.014	6.00.6
Cerebellum	0.0400.005	0.1000.006	0.0400.005	0.720.02	0.0610.014	5.00.4
Corona radiata	0.0350.005	0.0750.007	0.0240.003	0.770.02	0.0310.010	7.41.3
Internal/external capsule	0.0300.003	0.0930.024	0.0320.008	0.740.00	0.0320.009	5.81.2

 Values are the meanss.d. of the means from each of the three animals. The means of two of the animals were obtained from four different PET scans; the mean of the third animal is of a single scan.