Journal of Cerebral Blood Flow & Metabolism

FIGURE 3

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Measurement of regional rates of cerebral protein synthesis with L-[1-11C]leucine and PET with correction for recycling of tissue amino acids: II. Validation in rhesus monkeys

Carolyn Beebe Smith, Kathleen C Schmidt, Mei Qin, Thomas V Burlin, Michelle P Cook, Julia Kang, Richard C Saunders, John D Bacher, Richard E Carson, Michael A Channing, William C Eckelman, Peter Herscovitch, Peter Laverman and Bik-Kee Vuong

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Figure 3.

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Time courses of 11C activity from a typical study after an intravenous injection over 1 min of 0.31 GBq L-[1-11C]leucine in primary visual cortex (A) and internal/external capsule (B). Open circles (circle) represent the total activity measured at each time point in the ROI. The solid lines are the activities predicted by the model. It was assumed that 11CO2 made a negligible contribution to the total activity.

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