Journal of Cerebral Blood Flow & Metabolism

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Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection

Louise D McCullough, Zhiyuan Zeng, Kathleen K Blizzard, Indira Debchoudhury and Patricia D Hurn

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Figure 1.

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Infarct size (expressed as % of contralateral structure) in ovary-intact nNOS-/- versus wild-type (WT) female mice. There is a significant increase (* P<0.001) in total, cortical (CTX) and striatal (CP) infarct volume in nNOS-/- females compared to WT.

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