TABLE OF CONTENTS
Volume 25, Issue S1 (August 2005)
Brain Metabolism |
Neuro-inflammation |
Neuroinflammation |
Clinical Stroke and Thrombolysis |
CBF Regulation |
Regeneration and Plasticity |
White Matter, Brain Edema, Blood Brain Barrier |
Endogenous Neuroprotection |
Neuroimaging |
Mechanisms of Cell Death |
Gene Expression and Cell Therapy |
Experimental Models and Methods |
Neurointensive Care, Monitoring, Trauma |
Neurotransmitters and Receptors |
PET Methods for Alzheimer's Disease |
PET Methods for Alzheimer's Disease |
PET Methods for Alzheimer's Disease |
New PET Tracers |
Animal PET Methodology |
Tracer Kinetic Modeling |
Neurotransmitter Release |
BRAINPET |
Physiological Basis of Functional Imaging |
Pleiotropic Actions of Tissue Plasminogen Activator |
In Vivo Cell Tracking and Gene Expression |
Cell and Gene Therapy |
Cerebrovascular Dysfunction in Dementia |
The Ischemic Penumbra |
Heterogeneity in Cerebral Metabolism and Blood Flow |
Plasticity and Recovery after Stroke |
Imaging Neurotransmission with PET |
Brain Metabolism
Oral session
Oral session
Intensive insulin therapy is associated with reduced extracellular glucose and increased oxygen extraction fraction after severe traumatic brain injury
Paul Vespa, Marvin Bergsneider, David McArthur, H M Wu, S C Huang, Jeffry Alger, Thomas Glenn and David Hovda
J Cereb Blood Flow Metab 25: S60-S60; doi:10.1038/sj.jcbfm.9591524.0060
Translational complex aggregation after transient cerebral ischemia
Chunli Liu, Maryann Martone, Pengfei Ge, Fan Zhang, Shaoyi Chen and Bingren Hu
J Cereb Blood Flow Metab 25: S61-S61; doi:10.1038/sj.jcbfm.9591524.0061
Glucose utilization in neurons in rat brain evaluated with fluorescent analogue of deoxyglucose
Yoshiaki Itoh, Rie Takaoka, Takato Abe, Norio Tanahashi and Norihiro Suzuki
J Cereb Blood Flow Metab 25: S62-S62; doi:10.1038/sj.jcbfm.9591524.0062
Glucose uptake and metabolism in the human brain during hypoglycaemia assessed by in vivo magnetic resonance
Marinette van der Graaf, Bastiaan E de Galan, Dennis W J Klomp, Laura M Parkes, Cees J J Tack and Arend Heerschap
J Cereb Blood Flow Metab 25: S63-S63; doi:10.1038/sj.jcbfm.9591524.0063
Metabolic abnormalities precede pathologic changes in the G93A SOD1 mouse model of ALS
Jon-Paul P DiMauro, Lichuan Yang, Sara W Fuller and Susan E Browne
J Cereb Blood Flow Metab 25: S64-S64; doi:10.1038/sj.jcbfm.9591524.0064
Functional distinctions among baseline, control, and default modes of brain operation
Manouchehr S Vafaee and Albert Gjedde
J Cereb Blood Flow Metab 25: S65-S65; doi:10.1038/sj.jcbfm.9591524.0065
Activity-dependent oxygen transients in rat cerebellar cortex are blocked by synaptic inhibition
Kirsten Caesar and Martin Lauritzen
J Cereb Blood Flow Metab 25: S66-S66; doi:10.1038/sj.jcbfm.9591524.0066
Oral session
Poster Session
The stress hormone corticosterone inhibits glucose-, but not lactate-supported hippocampal LTP
Ralphiel S Payne and Avital Schurr
J Cereb Blood Flow Metab 25: S67-S67; doi:10.1038/sj.jcbfm.9591524.0067
A role of lactate in neuronal energy metabolism: Investigation with dynamic living brain slice imaging system
Mikako Ogawa, Hiroshi Watabe, Noboru Teramoto, Takuya Hayashi, Yoshinori Miyake, Hidehiro Iida and Yasuhiro Magata
J Cereb Blood Flow Metab 25: S68-S68; doi:10.1038/sj.jcbfm.9591524.0068
Reduced regional CMRGluc suppression in newborn piglets during thiopental-induced burst suppression
Reinhard Bauer, Bernd Walter, Frank Füchtner, Rainer Hinz, Hiroto Kuwabara and Peter Brust
J Cereb Blood Flow Metab 25: S69-S69; doi:10.1038/sj.jcbfm.9591524.0069
Ampakine CX546 bolsters energetic response of astrocytes: A novel target for cognitive-enhancing drugs acting as AMPA receptor modulators
Luc Pellerin and Pierre J Magistretti
J Cereb Blood Flow Metab 25: S70-S70; doi:10.1038/sj.jcbfm.9591524.0070
The central role of astrocytes in neurometabolic coupling : A decade's perspective
Pierre J Magistretti and Luc Pellerin
J Cereb Blood Flow Metab 25: S71-S71; doi:10.1038/sj.jcbfm.9591524.0071
Theoretical support for the astrocyte-neuron lactate shuttle hypothesis. I. Modeling neuronal and astrocytic NADH/NAD+ kinetics
Agnès Aubert, Luc Pellerin, Pierre J Magistretti and Robert Costalat
J Cereb Blood Flow Metab 25: S72-S72; doi:10.1038/sj.jcbfm.9591524.0072
Biphasic metabolic adaptation to hypoxia in rat astrocytes
Celine Vega, Leroy Sachleben, David Gozal and Evelyne Gozal
J Cereb Blood Flow Metab 25: S73-S73; doi:10.1038/sj.jcbfm.9591524.0073
Effects of pro-inflammatory cytokines and beta-amyloid peptide on glucose metabolism in primary cultures of astrocytes
Mathilde Gavillet, Igor Allaman, Luc Pellerin and Pierre J Magistretti
J Cereb Blood Flow Metab 25: S74-S74; doi:10.1038/sj.jcbfm.9591524.0074
Oxygen metabolism, electrophysiological activity and cerebral blood flow in rat sensory cortex
Pia Enager, Nikolas Offenhauser and Martin Lauritzen
J Cereb Blood Flow Metab 25: S75-S75; doi:10.1038/sj.jcbfm.9591524.0075
Neuroenergetic basis of regional temperature dynamics in brain
Hubert K F Trübel, Laura I Sacolick and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S76-S76; doi:10.1038/sj.jcbfm.9591524.0076
Hyperoxidation of NAD(P)H redox state after anoxia and reoxygenation: Effects of nitric oxide and PARP-1 inhibition
Sibel Kahraman and Gary Fiskum
J Cereb Blood Flow Metab 25: S77-S77; doi:10.1038/sj.jcbfm.9591524.0077
Activity-induced tissue oxygenation changes in rat cerebellar cortex: Interplay of postsynaptic activity and cerebral blood flow
Nikolas Offenhauser, Kirsten Thomsen, Kirsten Caesar and Martin Lauritzen
J Cereb Blood Flow Metab 25: S78-S78; doi:10.1038/sj.jcbfm.9591524.0078
Perturbation of human cerebral energetics with chronic ketosis
Jullie W Pan, C J Segal-Isaacson, Monika Jamrozek, Brandy Cowell and Anne Obertance
J Cereb Blood Flow Metab 25: S79-S79; doi:10.1038/sj.jcbfm.9591524.0079
Is oxygen insufficiency compensated during acute ischemia? - A PET study in an ischemic model of non-human primates
Rishu Piao, Takuya Hayashi, Nobuyuki Kudomi, Noboru Teramoto, Yoichiro Ohta and Hedehiro Iida
J Cereb Blood Flow Metab 25: S80-S80; doi:10.1038/sj.jcbfm.9591524.0080
Oxygen consumption by spiking activity in rat cerebellum
Kirsten Thomsen and Martin Lauritzen
J Cereb Blood Flow Metab 25: S81-S81; doi:10.1038/sj.jcbfm.9591524.0081
Effectively truncated TCA cycle during profound hypoglycemia
Roland N Auer, Randy L Tyson and Garnette R Sutherland
J Cereb Blood Flow Metab 25: S82-S82; doi:10.1038/sj.jcbfm.9591524.0082
MRI & 31P MRS studies of brain energetics in a model of cerebral vasoconstriction
Raman Saggy, John P Lowe, Andrew M Blamire, Daniel C Anthony, Peter Styles and Nicola R Sibson
J Cereb Blood Flow Metab 25: S83-S83; doi:10.1038/sj.jcbfm.9591524.0083
Turnover of extra-cellular glucose and lactate in the rat striatum estimated by equilibrium micro-dialysis
Maria M Rhemrev-Boom, Gea M R Leegsma-Vogt, Jakob Korf, Folkert Postema and Kor Venema
J Cereb Blood Flow Metab 25: S84-S84; doi:10.1038/sj.jcbfm.9591524.0084
Sleep-dependent changes in the cerebral metabolic rate of oxygen consumption in newborn lambs
Alessandro Silvani, Valentina Asti, Chiara Berteotti, Tijana Bojic, Vera Ferrari, Carlo Franzini, Daniel A Grant, Pierluigi Lenzi, Adrian M Walker and Giovanna Zoccoli
J Cereb Blood Flow Metab 25: S85-S85; doi:10.1038/sj.jcbfm.9591524.0085
The blood-brain uptake of 3-O-methyl D-glucose may be mainly interstitial over times less than 45 seconds
Joseph D Fenstermacher, Ling Wei, Daniel Bereczki, Tadahiro Otsuka, Jiann-Liang Chen, Franz-Josef Hans, Virgil Acuff and Clifford S Patlak
J Cereb Blood Flow Metab 25: S86-S86; doi:10.1038/sj.jcbfm.9591524.0086
Near-infrared spectroscopy measurements of cerebral blood flow and oxygen consumption following hypoxia-ischemia in newborn piglets
Kenneth M Tichauer, Derek W Brown, Jennifer Hadway, Ting-Yim Lee and Keith St Lawrence
J Cereb Blood Flow Metab 25: S87-S87; doi:10.1038/sj.jcbfm.9591524.0087
Near-infrared spectroscopy measurement of cerebral oxidative metabolism: A validation study
Kenneth M Tichauer, Jennifer Hadway, Ting-Yim Lee and Keith St Lawrence
J Cereb Blood Flow Metab 25: S88-S88; doi:10.1038/sj.jcbfm.9591524.0088
The adverse effects of hyperglycemia during transient focal ischemia in rats are not attributable to increased plasma corticosteroids or neutrophil infiltration
Abraham Martín, Angel Chamorro and Anna M Planas
J Cereb Blood Flow Metab 25: S89-S89; doi:10.1038/sj.jcbfm.9591524.0089
Theoretical support for the astrocyte-neuron lactate shuttle hypothesis. II. Modeling brain lactate kinetics
Agnès Aubert, Robert Costalat, Pierre J Magistretti and Luc Pellerin
J Cereb Blood Flow Metab 25: S90-S90; doi:10.1038/sj.jcbfm.9591524.0090
CBF Regulation
Oral session
Oral session
NADPH oxidase-derived free radicals mediate neurovascular dysfunction in models of Alzheimer's disease
Costantino Iadecola, Laibaik Park, Josef Anrather and George Carlson
J Cereb Blood Flow Metab 25: S155-S155; doi:10.1038/sj.jcbfm.9591524.0155
Cerebral vascular effects of angiotensin II: New insights from genetic models
Frank M Faraci, Mary L Modrick, Kathryn G Lamping, Curt D Sigmund and Sean P Didion
J Cereb Blood Flow Metab 25: S156-S156; doi:10.1038/sj.jcbfm.9591524.0156
Reversal of fully developed cerebrovascular dysfunctions in two transgenic mouse models of Alzheimer's disease
Nektaria Nicolakakis, Xin-Kang Tong and Edith Hamel
J Cereb Blood Flow Metab 25: S157-S157; doi:10.1038/sj.jcbfm.9591524.0157
The use of OPS imaging to detect microvascular disturbances in cerebral ischemia
Frits A Pennings, Can Ince and Gerrit J Bouma
J Cereb Blood Flow Metab 25: S158-S158; doi:10.1038/sj.jcbfm.9591524.0158
Chemical or electrical stimulation of basal forebrain neurons activates specific subsets of cortical GABA-interneurons in parallel with increases in cortical cerebral blood flow
Ara Kocharyan, Priscilla Fernandes, Nella Serluca, Elvire Vaucher and Edith Hamel
J Cereb Blood Flow Metab 25: S159-S159; doi:10.1038/sj.jcbfm.9591524.0159
Role of astrocytes and gap junctions in seizure-induced pial arteriolar dilations in rats
Hao-Liang Xu and Dale A Pelligrino
J Cereb Blood Flow Metab 25: S160-S160; doi:10.1038/sj.jcbfm.9591524.0160
Oral session
Poster Session
Interaction of adenosine and cytochrome P450 epoxygenase pathways in neurovascular coupling during whisker stimulation
Yanrong Shi, John R Falck, David R Harder and Raymond C Koehler
J Cereb Blood Flow Metab 25: S161-S161; doi:10.1038/sj.jcbfm.9591524.0161
Flow-induced cerebral vasodilatation involves activation of PI3-kinase and production of reactive oxygen species
Christopher G Sobey, Grant R Drummond and Tamara M Paravicini
J Cereb Blood Flow Metab 25: S162-S162; doi:10.1038/sj.jcbfm.9591524.0162
Is the vascular TREK-1 potentially involved in PUFAS-induced neuronal activation
Nicolas Blondeau, Gisèle Jarretou, Pierre Gounon, Valérie Giordanengo, Michel Lazdunski and Catherine Heurteaux
J Cereb Blood Flow Metab 25: S163-S163; doi:10.1038/sj.jcbfm.9591524.0163
Spatial and temporal heterogeneity of single capillary plasma flow and RBC tracking in the rat cerebral cortex
Minoru Tomita, Istvan Schiszler, Hidetaka Takeda, Yutaka Tomita, Takashi Osada, Miyuki Unekawa, Norio Tanahashi and Norihiro Suzuki
J Cereb Blood Flow Metab 25: S164-S164; doi:10.1038/sj.jcbfm.9591524.0164
A compact physiological model of the autoregulation of cerebral blood vessels
Alexander B Rowley, Christopher J Stephens and Stephen J Payne
J Cereb Blood Flow Metab 25: S165-S165; doi:10.1038/sj.jcbfm.9591524.0165
Implication of nociceptin in alterations in cerebral blood flow regulation following postnatal exposure to ethanol in rats
Won Suk Lee, Su Yeon Ko, Jeong Hee Kim and Dong Hwan Cho
J Cereb Blood Flow Metab 25: S166-S166; doi:10.1038/sj.jcbfm.9591524.0166
Perturbation of intraparenchymal arterioles during K+-induced cortical spreading depression in cats
Takashi Osada, Minotu Tomita, Norio Tanahashi, Hidetaka Takeda, Masahiro Kobari, Manabu Ohtomo and Norihiro Suzuki
J Cereb Blood Flow Metab 25: S167-S167; doi:10.1038/sj.jcbfm.9591524.0167
Stellate cells release NO and induce vasodilation of intraparenchymal blood vessels in rat cerebellar slices
Armelle Rancillac, Manon Guille, Xin-Kang Tong, Hélène Geoffroy, Stéphane Arbault, Edith Hamel, Christian Amatore, Jean Rossier and Bruno Cauli
J Cereb Blood Flow Metab 25: S168-S168; doi:10.1038/sj.jcbfm.9591524.0168
Local oxygen delivery evoked by hindpaw stimulation is the same before and after isovolemic hemodilution in rat somatosensory cortex
Masakatsu Ureshi and Iwao Kanno
J Cereb Blood Flow Metab 25: S169-S169; doi:10.1038/sj.jcbfm.9591524.0169
Intramicrovascular behavior of platelets in rat brain observed by high-speed laser confocal fluorescence microscopy
Norio Tanahashi, Hidetaka Takeda, Takasi Osada, Kouichi Ohki, Miyuki Unekawa, Minoru Tomita and Norihiro Suzuki
J Cereb Blood Flow Metab 25: S170-S170; doi:10.1038/sj.jcbfm.9591524.0170
Nonlinear correlation between evoked local cerebral blood flow and field potential in rat somatosensory cortex as a function of stimulus current
Masakatsu Ureshi and Iwao Kanno
J Cereb Blood Flow Metab 25: S171-S171; doi:10.1038/sj.jcbfm.9591524.0171
Transforming growth factor-
1 (TGF-1) alter endothelin-1 (ET-1)-induced contraction in brain vessels via upregulation of mitogen-activated protein kinase phosphatase 1 (MKP-1) and inactivation of P38 mitogen-activated protein kinase (P38 MAPK)
Xin-Kang Tong and Edith Hamel
J Cereb Blood Flow Metab 25: S172-S172; doi:10.1038/sj.jcbfm.9591524.0172
Vascular fibrosis versus amyloid beta (A)-induced oxidative stress in the cerebrovascular pathology associated with Alzheimer's disease (AD)
Xin-Kang Tong, Nektaria Nicolakakis and Edith Hamel
J Cereb Blood Flow Metab 25: S173-S173; doi:10.1038/sj.jcbfm.9591524.0173
Changes of flow velocity and RBC tracking in single capillaries and capillary densities during severe hypotension in rat brain
Hidetaka Takeda, Minoru Tomita, Istvan Schiszler, Yutaka Tomita, Takashi Osada, Kouichi Ohki, Miyuki Unekawa, Norio Tanahashi and Norihiro Suzuki
J Cereb Blood Flow Metab 25: S174-S174; doi:10.1038/sj.jcbfm.9591524.0174
Cerebral perfusion pressure or arterial pressure only: How to assess dynamic cerebral autoregulation more accurately?
Piotr Smielewski, Phil Lewis, Marek Czosnyka and John D Pickard
J Cereb Blood Flow Metab 25: S175-S175; doi:10.1038/sj.jcbfm.9591524.0175
Evaluation of critical hemodynamic status induced by acetazolamide challenge in patients with cerebrovascular disease: Assessment of regional perfusion pressure
Hidehiko Okazawa, Tatsuro Tsuchida, Yoshikazu Arai, Tetsuya Mori, Masato Kobayashi, Fumiko Tanaka and Yoshiharu Yonekura
J Cereb Blood Flow Metab 25: S176-S176; doi:10.1038/sj.jcbfm.9591524.0176
'Ecstasy' as a risk factor in stroke: A laboratory investigation of 3, 4-methylenedioxymethamphetamine-induced cerebrovascular dysfunction
Linda Ferrington, Douglas E McBean, Henry J Olverman and Paul A T Kelly
J Cereb Blood Flow Metab 25: S177-S177; doi:10.1038/sj.jcbfm.9591524.0177
NOS inhibitor attenuates vasodilatation by trigeminal stimulation
Michinari Fukuda, Shinya Tsukahara, Kenzo Koizumi, Shigeyoshi Maruyama, Norihiro Suzuki and Fumihiko Sakai
J Cereb Blood Flow Metab 25: S178-S178; doi:10.1038/sj.jcbfm.9591524.0178
Angiotensin II type 1 (AT1)-receptor blocker prevents impairment of endothelium-dependent cerebral vasodilation by acute cigarette smoking in rats
Mami Iida, Hiroki Iida, Motoyasu Takenaka, Hisayoshi Fujiwara and Shuji Dohi
J Cereb Blood Flow Metab 25: S179-S179; doi:10.1038/sj.jcbfm.9591524.0179
Cerebral vascular mitochondrial efficiency is increased by estrogen treatment
Chris Stirone, Diana N Krause, Vincent Procaccio and Sue P Duckles
J Cereb Blood Flow Metab 25: S180-S180; doi:10.1038/sj.jcbfm.9591524.0180
Age increases overall complexity of human spontaneous CBV fluctuations
Andras Eke, Peter Herman and Marton Hajnal
J Cereb Blood Flow Metab 25: S181-S181; doi:10.1038/sj.jcbfm.9591524.0181
Essential cerebral distribution of cardiac output in infants
Takashi Kusaka, Kenichi Isobe, Kensuke Okubo, Keiko Nagano and Susumu Itoh
J Cereb Blood Flow Metab 25: S182-S182; doi:10.1038/sj.jcbfm.9591524.0182
Cerebral haemodynamics assessed by transcranial Doppler ultrasonography during orthotopic liver transplant. A preliminary report
Eric A Schmidt, Marek Czosnyka, David Tew, John R Klink, Marcella Balestreri, John D Pickard and Basil F Matta
J Cereb Blood Flow Metab 25: S183-S183; doi:10.1038/sj.jcbfm.9591524.0183
Delivery of a deltaPKC inhibitor peptide improves stroke survival in a rat model of hypertension, and increases cerebral blood flow following transient focal ischemia in normotensive rats
Rachel Bright, Koichi Inagaki, Midori A Yenari, Gary K Steinberg and Daria Mochly-Rosen
J Cereb Blood Flow Metab 25: S184-S184; doi:10.1038/sj.jcbfm.9591524.0184
Circadian periodicity in cerebral blood flow: Studies in normotensive and transgenic hypertensive rats
Constantin A Wauschkuhn, Klaus Witte, Stefan Gorbey, Björn Lemmer and Lothar Schilling
J Cereb Blood Flow Metab 25: S185-S185; doi:10.1038/sj.jcbfm.9591524.0185
Fractal properties of neurophysiologic signals in rat somatosensory cortex
Peter Herman, Shaun A Wahab, Andras Eke and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S186-S186; doi:10.1038/sj.jcbfm.9591524.0186
Interactions between the heme oxygenase, cyclooxygenase and nitric oxide synthase pathways in the regulation of the resting hypothalamic blood flow
Béla Horváth, László Hortobágyi, Péter Sándor and Zoltán Benyó
J Cereb Blood Flow Metab 25: S187-S187; doi:10.1038/sj.jcbfm.9591524.0187
Evaluation of the mathematical assumption underlying numerical identification modeling of cerebrovascular pressure transmission
Michael L Daley, Charles W Leffler, Marek Czosnyka and John D Pickard
J Cereb Blood Flow Metab 25: S188-S188; doi:10.1038/sj.jcbfm.9591524.0188
Inhibition of the cannabinoid-1 receptor enhances the cerebrocortical hyperemic response to hypoxia/hypercapnia
Miriam Ishiguro, Zsombor Lacza, Eszter M Horváth, Zoltán Járai, Péter Sándor and Zoltán Benyó
J Cereb Blood Flow Metab 25: S189-S189; doi:10.1038/sj.jcbfm.9591524.0189
Medullary epithelial sodium channels (ENAC) participate in cerebral blood flow (CBF) autoregulation
Eugene Golanov, Heather Drummond, Jasleen Shant, Benjamin Clower and Betty Chen
J Cereb Blood Flow Metab 25: S190-S190; doi:10.1038/sj.jcbfm.9591524.0190
Transcriptional and translational mechanisms for the reciprocal control of iNOS and endothelin 1 expression in brain microvessels after traumatic brain injury (TBI)
Christian Kreipke, Jose Rafols and Theodor Petrov
J Cereb Blood Flow Metab 25: S191-S191; doi:10.1038/sj.jcbfm.9591524.0191
Combined measurements of cerebellar blood flow, local field potentials and glucose utilization during climbing fibres stimulation: Effect of postsynaptic excitatory activity
Aïcha Douhou, Kirsten Caesar, Nikolas Offenhauser, Martin Lauritzen and Gilles Bonvento
J Cereb Blood Flow Metab 25: S192-S192; doi:10.1038/sj.jcbfm.9591524.0192
Investigation of the changes in cerebral tissue oxygenation measured with near infrared spectroscopy in response to moderate hypercapnia
Ilias Tachtsidis, Holie Jones, Caroline Oliver, Dave T Delpy, Martin Smith and Clare E Elwell
J Cereb Blood Flow Metab 25: S193-S193; doi:10.1038/sj.jcbfm.9591524.0193
Circulating tumor necrosis factor-
alters cerebral blood flow and microvascular ultrastructure through nitric oxide release in the rat brain
Eszter Farkas, Peter Antal, Valeria Toth-Szuki, Ibolya G Farkas, Andras Mihaly and Ferenc Bari
J Cereb Blood Flow Metab 25: S194-S194; doi:10.1038/sj.jcbfm.9591524.0194
Fractal patterns of local and global CBF in rat brain during hypotension
Peter Herman, Hubert Trübel, Fahmeed Hyder and Andras Eke
J Cereb Blood Flow Metab 25: S195-S195; doi:10.1038/sj.jcbfm.9591524.0195
Evoked potentials and activation flow coupling in endotoxin mediated sepsis syndrome in rats
Bernhard Rosengarten, Mirko Hecht, Ardeschir Ghofrani and Manfred Kaps
J Cereb Blood Flow Metab 25: S196-S196; doi:10.1038/sj.jcbfm.9591524.0196
Cerebral blood flow autoregulation in a rat model of subarachnoid hemorrhage as determined with laser Doppler flowmetry and the intra-arterial 133xenon method
Jan Tonnesen, Erik H Larsen, John Hauerberg, Olaf B Paulson and Gitte M Knudsen
J Cereb Blood Flow Metab 25: S197-S197; doi:10.1038/sj.jcbfm.9591524.0197
Effect of caffeine on theophyliine on cerebral blood flow response to brain activation: In vitro and in vivo studies
Joseph R Meno, Thien-son K Nguyen, Elise M Jensen, G Alexander West, Leonid Groysman, David K Kung, Al C Ngai, Gavin W Britz and H Richard Winn
J Cereb Blood Flow Metab 25: S198-S198; doi:10.1038/sj.jcbfm.9591524.0198
Regional variability in the CBF response to mild hypotension correlates with heterogeneous CBF after focal cerebral ischemia
Alexander Kharlamov and Stephen C Jones
J Cereb Blood Flow Metab 25: S199-S199; doi:10.1038/sj.jcbfm.9591524.0199
Effects of volatile agents on neurophysiology in -chloralose anesthetized rats
Basavaraju G Sanganahalli, Peter Herman and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S200-S200; doi:10.1038/sj.jcbfm.9591524.0200
Cell-specific expression and function of IKCa channels in cerebral endothelial cells but not smooth muscle cells: Relevance to the mechanism of EDHF-mediated dilation
Christina Hatfield and Marrelli Sean
J Cereb Blood Flow Metab 25: S201-S201; doi:10.1038/sj.jcbfm.9591524.0201
The effect of cerebral emboli formations after conventional, off-pump and assisted beating heart myocardial revascularisation on regional cerebral perfusion and water content in an adult porcine model
Benjamin O Bierbach, Matthias Meier, Walter Kasper-Koenig, Axel Heimann, Beat Alessandri, Georg Horstick, Christian F Vahl and Oliver Kempski
J Cereb Blood Flow Metab 25: S202-S202; doi:10.1038/sj.jcbfm.9591524.0202
Myogenic stretch of ovine cerebral arteries induces both MLC phosphorylation and thin-filament activation in an age-dependent manner
Renan Sandoval, Melody M Chang, James M Williams and William J Pearce
J Cereb Blood Flow Metab 25: S203-S203; doi:10.1038/sj.jcbfm.9591524.0203
Role of gap junctional communication in pial arteriole dilation during somatosensory stimulation
Al C Ngai, Jeffrey J Iliff, Gavin W Britz and H Richard Winn
J Cereb Blood Flow Metab 25: S204-S204; doi:10.1038/sj.jcbfm.9591524.0204
NADPH-oxidase activity and function is enhanced in the cerebral circulation and influenced by gender
Christopher G Sobey, Grant R Drummond and Alyson A Miller
J Cereb Blood Flow Metab 25: S205-S205; doi:10.1038/sj.jcbfm.9591524.0205
Adaptation of the hypothalamic blood flow to chronic nitric oxide synthase blockade
László Hortobágyi, Béla Kis, András Hrabák, Béla Horváth, Péter Sándor, David W Busija and Zoltán Benyó
J Cereb Blood Flow Metab 25: S206-S206; doi:10.1038/sj.jcbfm.9591524.0206
Allosteric release of nitric oxide from hemoglobin does not mediate neurovascular coupling
Christoph Leithner, Heike Sellien, Benjamin Rohrer, Georg Royl, Dirk Megow, Jens Steinbrink, Matthias Kohl-Bareis, Ulrich Dirnagl and Ute Lindauer
J Cereb Blood Flow Metab 25: S207-S207; doi:10.1038/sj.jcbfm.9591524.0207
Quantification of small microvascular system morphology in five rat brain areas
Joseph D Fenstermacher, Shinn-Zong Lin, Joseph A De Maro, Jia-Yi Wang, Wendy Akmentin, Gyongyi Gesztelyi and Ling Wei
J Cereb Blood Flow Metab 25: S208-S208; doi:10.1038/sj.jcbfm.9591524.0208
Clinical Stroke and Thrombolysis
Oral session
Oral session
Predicting effects of thrombolytic therapy in acute stroke patients using MR imaging
Ona Wu, Søren Christensen, Niels Hjort, Rick M Dijkhuizen, Thomas Kucinski, Jens Fiehler, Joachim Rother and Leif Ostergaard
J Cereb Blood Flow Metab 25: S113-S113; doi:10.1038/sj.jcbfm.9591524.0113
Ultrasound-augmented thrombolysis improves outcome in hyperglycaemic stroke
Sharyl Martini, Michael D Hill, Andrei V Alexandrov, Carlos A Molina and Thomas A Kent
J Cereb Blood Flow Metab 25: S114-S114; doi:10.1038/sj.jcbfm.9591524.0114
Albumin therapy for neuroprotection in ischemic stroke: Alias I trial
Myron D Ginsberg, Michael D Hill, Yuko Y Palesch, Karla J Ryckborst and Diego Tamariz
J Cereb Blood Flow Metab 25: S115-S115; doi:10.1038/sj.jcbfm.9591524.0115
Initial evidence for peri-infarct depolarization or cortical spreading depression as a cause of neurological deterioration in patients with subarachnoid haemorrhage
Robin Bhatia, Martyn G Boutelle, Parastoo Hashemi, Martin Fabricius, Martin Lauritzen, Susanne B Fuhr, Lisette Willumsen and Anthony J Strong
J Cereb Blood Flow Metab 25: S116-S116; doi:10.1038/sj.jcbfm.9591524.0116
A panel of biomarkers may successfully predict acute stroke diagnosis
Joan Montaner, Anna Rosell, Pilar Delgado, Marc Ribo, Francisco Purroy, Anna Penalba, Israel Fernandez-Cadenas, Carlos Molina and Jose Alvarez-Sabin
J Cereb Blood Flow Metab 25: S117-S117; doi:10.1038/sj.jcbfm.9591524.0117
Bilirubin production and oxidation in CSF of patients with cerebral vasospasm after subarachnoid hemorrhage
Gail Pyne-Geithman, Chad Morgan, Kenneth Wagner, Janice Carrozzella, Daniel Kanter, Elizabeth Dulaney, Mario Zuccarello and Joseph Clark
J Cereb Blood Flow Metab 25: S118-S118; doi:10.1038/sj.jcbfm.9591524.0118
Early proteomic markers of vasospasm can be identified in cerebral microdialysates of patients with subarachnoid hemorrhage
Martin H Maurer, Daniel Haux, Oliver W Sakowitz, Robert E Feldmann, Andreas W Unterberg and Wolfgang Kuschinsky
J Cereb Blood Flow Metab 25: S119-S119; doi:10.1038/sj.jcbfm.9591524.0119
Oral session
Poster Session
Changes in superficial temporal artery blood flow and cerebral hemodynamics of moyamoya disease after extracranial-intracranial bypass surgery
Shigeru Fujimoto, Kazunori Toyoda, Tooru Inoue, Yoko Yokoyama, Juro Jinnouchi, Koh Nakachi, Seiji Goto, Kotaro Yasumori, Setsuro Ibayashi and Yasushi Okada
J Cereb Blood Flow Metab 25: S120-S120; doi:10.1038/sj.jcbfm.9591524.0120
Evaluation of cerebral metabolism by multi-voxel proton magnetic resonance spectroscopy imaging before and after STA-MCA bypass
Kazunori Akaji, Hideichi Takayama, Masahito Kobayashi, Yoshio Tanizaki, Kenji Hiraga, Sadao Suga and Ban Mihara
J Cereb Blood Flow Metab 25: S121-S121; doi:10.1038/sj.jcbfm.9591524.0121
Melatonin reverses tissue-plasminogen activator (t-PA)-induced brain injury after intraluminal middle cerebral artery occlusion: Role of inducible NO synthase and phosphatidylinositol-3 kinase/Akt
Ertugrul Kilic, Ülkan Kilic, Claudio L Bassetti and Dirk M Hermann
J Cereb Blood Flow Metab 25: S122-S122; doi:10.1038/sj.jcbfm.9591524.0122
Elevation of plasma oxidized LDL in acute stroke patients is associated with ischemic lesion depicted by DWI and predictive of infarct enlargement
Masaaki Uno, Keiko Kitazato, Atsuhiko Suzue, Kyoko Nishi and Shinji Nagahiro
J Cereb Blood Flow Metab 25: S123-S123; doi:10.1038/sj.jcbfm.9591524.0123
Nitric oxide-based pathomechanism of delayed cerebral vasospasm after SAH
Ryszard Pluta, Carla Jung, Brian Iuliano and Edward Oldfield
J Cereb Blood Flow Metab 25: S124-S124; doi:10.1038/sj.jcbfm.9591524.0124
Imbalance between oxidant/antioxidant systems contributes to plaque vulnerability in patients who underwent carotid endarterectomy
Kyoko Nishi, Masaaki Uno, Keiko T Kitazato, Atsuhiko Suzue, Hao Liu, Hiroyuki Itabe and Shinji Nagahiro
J Cereb Blood Flow Metab 25: S125-S125; doi:10.1038/sj.jcbfm.9591524.0125
Mutivariate statistical differentiation of hemodynamic factors in chronic occlusive cerebrovascular disease with positron emission tomography – Analysis of 100 patients with moyamoya disease
Tadashi Nariai, Yoji Tanaka, Iwae Yu, Motoki Inaji, Kikuo Ohno, Kiichi Ishiwata, Michio Senda and Kenji Ishii
J Cereb Blood Flow Metab 25: S126-S126; doi:10.1038/sj.jcbfm.9591524.0126
Dynamic CT Perfusion imaging in subarachnoid hemorrhage related vasospasm
Amanda M Laslo, James D Eastwood, Fang Chen and Ting-Yim Lee
J Cereb Blood Flow Metab 25: S127-S127; doi:10.1038/sj.jcbfm.9591524.0127
Role of c-Jun N-terminal kinase in cerebral vasospasm of subarachnoid hemorrhage
Hiroshi Yatsushige, Mitsuo Yamaguchi, Changman Zhou, John H Calvert, Austin R T Colohan and John H Zhang
J Cereb Blood Flow Metab 25: S128-S128; doi:10.1038/sj.jcbfm.9591524.0128
Uric acid improves the beneficial effects of rt-PA in a rat model of thromboembolic ischemia
Eduardo Romanos, Anna M Planas and Angel Chamorro
J Cereb Blood Flow Metab 25: S129-S129; doi:10.1038/sj.jcbfm.9591524.0129
Subarachnoid hemorrhage in rats – neuroprotective efficacy of bradykinin B2 receptor blockade
Stefan Zausinger, Sonja Sporer, Serge Thal, Nikolaus Plesnila, Karsten Schöller and Robert Schmid-Elsaesser
J Cereb Blood Flow Metab 25: S130-S130; doi:10.1038/sj.jcbfm.9591524.0130
Plasma brain natriuretic peptide on the diagnosis of cardioembolic stroke due to paroxysmal atrial fibrillation
Takayuki Naya, Kazushi Yukiiri, Naohisa Hosomi, Tsutomu Takahashi and Masakazu Kohno
J Cereb Blood Flow Metab 25: S131-S131; doi:10.1038/sj.jcbfm.9591524.0131
Biochemical markers of acute ischemic stroke patients
Genki Mizukoshi, Ken-ichiro Katsura, Megumi Watanabe and Yasuo Katayama
J Cereb Blood Flow Metab 25: S132-S132; doi:10.1038/sj.jcbfm.9591524.0132
Mapping of ADC abnormalities associated with acute spontaneous intracerebral hematoma as evaluated by diffusion-weighted imaging
Enrico Fainardi, Stefano Ceruti, Massimo Borrelli, Andrea Saletti, Roberta Schivalocchi, Cristiano Azzini, Monia Russo, Michele Cavallo, Arturo Chieregato and Riccardo Tamarozzi
J Cereb Blood Flow Metab 25: S133-S133; doi:10.1038/sj.jcbfm.9591524.0133
Contractile and cytoskeletal protein changes in rabbit basilar artery 7 days after subarachnoid hemorrhage and effects of dexamethasone treatment
Philippe Gomis, Yves-Roger Tran Dinh, Christine Sercombe and Richard Sercombe
J Cereb Blood Flow Metab 25: S134-S134; doi:10.1038/sj.jcbfm.9591524.0134
Perioperative evaluation of carotid endarterectomy by 3D-CT angiography with refined reconstruction: Preliminary experience of CEA without conventional angiography
Hiroyuki Katano, Kojiro Kato, Atsushi Umemura and Kazuo Yamada
J Cereb Blood Flow Metab 25: S135-S135; doi:10.1038/sj.jcbfm.9591524.0135
Predicting the fate of acute ischemic lesion with CT-perfusion
Hiroshi Hagiwara, Hidenori Nakamura, Hironaka Igarashi, Tatsushi Kamiya and Yasuo Katayama
J Cereb Blood Flow Metab 25: S136-S136; doi:10.1038/sj.jcbfm.9591524.0136
Structure and function of cerebral microcirculation after subarachnoid hemorrhage caused by puncture of the bifurcation of the internal carotid artery in the rat
Katarzyna Borcuch, Radoslaw Michalik, Anna Domasiewicz, Zbigniew Czernicki, Michal Walski, Malgorzata Frontczak-Baniewicz and Ewa Kozniewska
J Cereb Blood Flow Metab 25: S137-S137; doi:10.1038/sj.jcbfm.9591524.0137
Protein kinase C inhibition blocks upregulation of ETB and 5-HT1B receptors and reverses cerebral blood flow reduction in subarachnoid haemorrhage of rats
Saema Beg, Jacob Hansen-Schwartz and Lars Edvinsson
J Cereb Blood Flow Metab 25: S138-S138; doi:10.1038/sj.jcbfm.9591524.0138
Determination of the time course of experimental cerebral vasospasm in the rat double subarachnoid hemorrhage model by neurological score, selective vertebro-basilar angiography, and perfusion weighted magnet resonance imaging
Hartmut Vatter, Stefan Weidauer, Juergen Konczalla, Edgar Dettmann, Michael Zimmermann, Friedhelm E Zanella and Volker Seifert
J Cereb Blood Flow Metab 25: S139-S139; doi:10.1038/sj.jcbfm.9591524.0139
Tissue-type plasminogen activator crosses the intact blood-brain barrier by LRP-mediated transcytosis : A phenomenon that is switched during oxygen glucose deprivation to an increased and LRP-independent process
Karim Benchenane, Carine Ali, Julien Brillault, Vincent Berezowski, Monica Fernandez-Monreal, Jose P Lopez-Attalaya, Julien Chuquet, Andre Nouvelot, Eric T MacKenzie, Marie-Pierre Dehouck, Romeo Cecchelli, Denis Vivien and Omar Touzani
J Cereb Blood Flow Metab 25: S140-S140; doi:10.1038/sj.jcbfm.9591524.0140
In vitro evaluation of the cerebrovascular effects of clazosentan, the first clinically effective endothelin-receptor antagonist for the treatment of cerebral vasospasm after subarachnoid hemorrhage
Hartmut Vatter, Michael Zimmermann, Veronika Tesanovic, Andreas Raabe, Volker Seifert and Lothar Schilling
J Cereb Blood Flow Metab 25: S141-S141; doi:10.1038/sj.jcbfm.9591524.0141
Cerebral hemodynamics and oxygen metabolism in occlusive cerebrovascular disease: Comparison between "misery perfusion" and "matched reduction in CBF and CMRO2"
Ken Okada, Hiroshi Ito, Eku Shimosegawa, Kentarou Inoue, Ryoui Goto, Shigeo Kinomura, Yasuyuki Taki, Shuichi Miura and Hiroshi Fukuda
J Cereb Blood Flow Metab 25: S142-S142; doi:10.1038/sj.jcbfm.9591524.0142
Ipsilateral thalamic diaschisis in patients with cortical infarction: Logistic regression analysis
Komaba Yuichi, Masahiro Mishina, Shiro Kobayashi and Yasuo Katayama
J Cereb Blood Flow Metab 25: S143-S143; doi:10.1038/sj.jcbfm.9591524.0143
Quality of preclinical evidence for neuroprotection in stroke
Tori O'Collins, Malcolm Macleod, Laura Horky, Dennis Young, Geoffrey Donnan and David Howells
J Cereb Blood Flow Metab 25: S144-S144; doi:10.1038/sj.jcbfm.9591524.0144
Cerebrovascular alteration in alcoholic patients
Piroska Szalay, Kornel Sipos, Attila Szucs and Michael Bodo
J Cereb Blood Flow Metab 25: S145-S145; doi:10.1038/sj.jcbfm.9591524.0145
Bedside monitoring of cerebral blood flow (CBF) in patients with cerebral vasospasm after subarachnoid hemorrhage
Regina Mudra, Peter Niederer and Emanuela Keller
J Cereb Blood Flow Metab 25: S146-S146; doi:10.1038/sj.jcbfm.9591524.0146
Adult-onset moyamoya disease with angiographically verified progression
Yasuyuki Ezaki, Keisuke Tsutsumi, Naoki Kitagawa and Izumi Nagata
J Cereb Blood Flow Metab 25: S147-S147; doi:10.1038/sj.jcbfm.9591524.0147
Relationships between vertebral artery diameter and dissecting aneurysm formation
Yoko Yokoyama, Shigeru Fujimoto, Kazunori Toyoda, Tooru Inoue, Juro Jinnouchi, Koh Nakachi, Seiji Gotoh, Daisuke Fukui, Kotaro Yasumori and Yasushi Okada
J Cereb Blood Flow Metab 25: S148-S148; doi:10.1038/sj.jcbfm.9591524.0148
Disease burden of ischemic stroke on functional ability of working
Shigeharu Takagi, Sari Sekiyama, Kentaro Tokuoka, Hiroyuki Mandokoro, Tomohide Onuki, Ryuya Kumazawa, Satoko Kobori, Tsuyoshi Uesugi and Takashi Yasuda
J Cereb Blood Flow Metab 25: S149-S149; doi:10.1038/sj.jcbfm.9591524.0149
Clinical differences between monoparesis and hemiparesis in pure motor stroke
Kiminobu Yonemura, Yoichiro Hashimoto and Makoto Uchino
J Cereb Blood Flow Metab 25: S150-S150; doi:10.1038/sj.jcbfm.9591524.0150
The acute and long-term prognosis of cerebral infarction on the basis of the clinical classification of the Oxfordshire community stroke project
Katsunori Isa, Takashi Tokashiki, Koichiro Okumura, Kunitoshi Iseki and Shuichi Takishita
J Cereb Blood Flow Metab 25: S151-S151; doi:10.1038/sj.jcbfm.9591524.0151
Dynamic changes of the pyramidal tract after ischemic stroke detected by MR tractography
Mette Møller, Jesper Frandsen, Grethe Andersen, Albert Gjedde and Peter Vestergaard-Poulsen
J Cereb Blood Flow Metab 25: S152-S152; doi:10.1038/sj.jcbfm.9591524.0152
Pharmacological neutropenia reduces thrombolysis-associated hemorrhagic complications after focal ischemia in rats
Sophie Gautier, Thavarak Ouk, Olivier Pétrault, Maud Laprais, Jacques Caron and Régis Bordet
J Cereb Blood Flow Metab 25: S153-S153; doi:10.1038/sj.jcbfm.9591524.0153
Statistical parametric analysis of cerebral blood flow in vascular dementia due to small-vessel disease using 99mTc-HMPAO SPECT
Hiroki Kato, Takuya Yoshikawa, Naohiko Oku, Yasuyuki Kimura, Katsufumi Kajimoto, Makiko Tanaka, Masatsugu Hori and Jun Hatazawa
J Cereb Blood Flow Metab 25: S154-S154; doi:10.1038/sj.jcbfm.9591524.0154
Endogenous Neuroprotection
Oral session
Oral session
17Beta - estradiol treatment improves neurohistopathological outcome after cardiac arrest and cardio pulmonary resuscitation in male mice
Ruediger R Noppens, Julia Kofler, Marjorie R Grafe, Patrica D Hurn and Richard J Traystman
J Cereb Blood Flow Metab 25: S280-S280; doi:10.1038/sj.jcbfm.9591524.0280
Hypothermia reduces influence of matrix metalloproteinase induction by EMMPRIN in experimental focal cerebral ischemia
Dorothe Burggraf, Helge K Martens and Gerhard F Hamann
J Cereb Blood Flow Metab 25: S281-S281; doi:10.1038/sj.jcbfm.9591524.0281
Transgenic erythropoietin protects from focal cerebral ischemia by a dual pathway involving both ERK-1/-2 and Akt
Ülkan Kilic, Ertugrul Kilic, Jorge Soliz, Claudio L Bassetti, Max Gassmann and Dirk M Hermann
J Cereb Blood Flow Metab 25: S282-S282; doi:10.1038/sj.jcbfm.9591524.0282
Cortical spreading depression elevates mRNAs encoding feedback inhibitors of inflammation: A novel mechanism of induced tolerance to ischemia
Katalin Kariko, Hiromi Muramatsu and Frank A Welsh
J Cereb Blood Flow Metab 25: S283-S283; doi:10.1038/sj.jcbfm.9591524.0283
Ischemic preconditioning prevents translational complex aggregation after transient cerebral ischemia
Chinli Liu, Shaoyi Chen and Bingren Hu
J Cereb Blood Flow Metab 25: S284-S284; doi:10.1038/sj.jcbfm.9591524.0284
Early CBF recovery predicts infarct reduction by ischemic preconditioning in a model of permanent middle cerebral artery occlusion in spontaneously hypertensive rats
Liang Zhao and Thaddeus S Nowak Jr.
J Cereb Blood Flow Metab 25: S285-S285; doi:10.1038/sj.jcbfm.9591524.0285
Oral session
Poster Session
Caspase-3 dependent proteolytic cleavage of 
PKC after ischemic preconditioning in the organotypic hippocampal slices
Kunjan R Dave, Ami P Raval and Miguel A Perez-Pinzon
J Cereb Blood Flow Metab 25: S286-S286; doi:10.1038/sj.jcbfm.9591524.0286
A-type potassium currents and neuroprotection after ischemia
Ping Deng, Zhi-Ping Pang, Zhigang Lei, Sojin Shikano, Qiaoxi Xiong, Min Li and Zao C Xu
J Cereb Blood Flow Metab 25: S287-S287; doi:10.1038/sj.jcbfm.9591524.0287
Erythropoietin regulated by hypoxia-inducible factor-1 and recombinant human erythropoietin protect cultured neurons from hypoxic and reoxygenic injury
Ruiqin Liu, Asuka Suzuki, Yoshikuni Mizuno and Takao Urabe
J Cereb Blood Flow Metab 25: S288-S288; doi:10.1038/sj.jcbfm.9591524.0288
Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying mutant sod1 gene
Tetsuro Murakami, Tetsuya Nagata, Isao Nagano, Takeshi Hayashi, Mikio Shoji and Koji Abe
J Cereb Blood Flow Metab 25: S289-S289; doi:10.1038/sj.jcbfm.9591524.0289
Gender differences in isoflurane preconditioning and experimental stroke
Hideto Kitano, Patricia D Hurn and Stephanie J Murphy
J Cereb Blood Flow Metab 25: S290-S290; doi:10.1038/sj.jcbfm.9591524.0290
Estradiol increases signal transducer and activator of transcription (STAT3) phosphorylation and DNA binding in brain nuclear extract after MCAO occlusion
Suzan Dziennis, Jennifer M Young, Vanessa R Anderson, Patricia D Hurn and Nabil J Alkayed
J Cereb Blood Flow Metab 25: S291-S291; doi:10.1038/sj.jcbfm.9591524.0291
Chronic mild reduction of cerebral perfusion pressure induces ischemic tolerance in focal cerebral ischemia
Kazuo Kitagawa, Yoshiki Yagita, Tsutomu Sasaki, Emi Omura, Kenichi Todo, Kohji Matsushita and Masatsugu Hori
J Cereb Blood Flow Metab 25: S292-S292; doi:10.1038/sj.jcbfm.9591524.0292
Brain aromatase overexpression does not reduce ischaemic damage nor improve long term functional outcome after experimental stroke: A magnetic resonance imaging and behavioural study
Hilary V O Carswell, Kirsty Gordon, Tracy Farr, Jim M Mullin, Lindsay Gallagher, Barrie Condon and I Mhairi Macrae
J Cereb Blood Flow Metab 25: S293-S293; doi:10.1038/sj.jcbfm.9591524.0293
Erythropoietin prevents spinal cord damage and affecting enzyme levels of brain-derived neurotrophic factor after transient spinal cord ischemia in rabbits
Hiroaki Kokubo, Masahiro Sakurai, Koji Abe, Yasuto Itoyama and Koichi Tabayashi
J Cereb Blood Flow Metab 25: S294-S294; doi:10.1038/sj.jcbfm.9591524.0294
A small cortical lesion increases the expression of feedback inhibitors of proinflammatory cytokine–signaling
Hiromi Muramatsu, Katalin Karikó and Frank A Welsh
J Cereb Blood Flow Metab 25: S295-S295; doi:10.1038/sj.jcbfm.9591524.0295
Mitochondrial KATP channel opening initiate ischemic preconditioning in organotypic hippocampal slice cultures
Miguel A Pérez-Pinzón and Ami P Raval
J Cereb Blood Flow Metab 25: S296-S296; doi:10.1038/sj.jcbfm.9591524.0296
Quantitative evaluation of the neuroprotective effects of thiopental sodium, propofol and halothane on brain ischemia in gerbils: Use of a logistic regression curve
Motomu Kobayashi, Yoshimasa Takeda, Ken Takata, Hisami Aoe and Kiyoshi Morita
J Cereb Blood Flow Metab 25: S297-S297; doi:10.1038/sj.jcbfm.9591524.0297
Improved regional cerebral blood flow mediates tolerance afforded by ischemic preconditioning
Lisa C Hoyte and Alastair M Buchan
J Cereb Blood Flow Metab 25: S298-S298; doi:10.1038/sj.jcbfm.9591524.0298
Role of P450 aromatase in sex-specific astrocyte cell death
Mingyue Liu, Patrica D Hurn, Charles E Roselli and Nabil J Alkayed
J Cereb Blood Flow Metab 25: S299-S299; doi:10.1038/sj.jcbfm.9591524.0299
Ischemic preconditioning protects the hippocampal CA1 neurons by inhibiting synaptic activity in rat
Thomas J Sick, Ami P Raval, Isabel Saul, Kunjan R Dave, Raul Busto and Miguel A Pérez-Pinzón
J Cereb Blood Flow Metab 25: S300-S300; doi:10.1038/sj.jcbfm.9591524.0300
Analogous neuroprotection induced by resveratrol and ischemic preconditioning in CA1 region of hippocampus after ischemia
Ami P Raval, Kunjan R Dave and Miguel A Pérez-Pinzón
J Cereb Blood Flow Metab 25: S301-S301; doi:10.1038/sj.jcbfm.9591524.0301
Effect of PKC translocation on respiration in synaptosomal mitochondria after ischemic preconditioning
Gabriel Santamarina, Edilberto Alvarez, Kunjan R Dave, Isabel Saul, Raul Busto and Miguel A Perez-Pinzon
J Cereb Blood Flow Metab 25: S302-S302; doi:10.1038/sj.jcbfm.9591524.0302
Possible role of cerebellar fastigial nucleus in preconditioned neuroprotection
Shadon Rollins, Betty Chen and Eugene Golanov
J Cereb Blood Flow Metab 25: S303-S303; doi:10.1038/sj.jcbfm.9591524.0303
Ischemic preconditioning promotes neuroprotection via cyclooxygenase-2 induction in vitro
Eun Joo Kim, Ami P Raval and Miguel A Perez-Pinzon
J Cereb Blood Flow Metab 25: S304-S304; doi:10.1038/sj.jcbfm.9591524.0304
In vivo ischemic preconditioning by caspase-3 cleavage of poly(ADP-ribose) polymerase-1
Philippe E Garnier, San Won Suh, Weihai Ying and Raymond A Swanson
J Cereb Blood Flow Metab 25: S305-S305; doi:10.1038/sj.jcbfm.9591524.0305
Unique properties of ischemic tolerance following intermittent hypoxia
W David Lust, Jorge L Gamboa, Jose Valerio, Michael Buczek, Svetlana Pundik and Warren R Selman
J Cereb Blood Flow Metab 25: S306-S306; doi:10.1038/sj.jcbfm.9591524.0306
Reduced infarct volumes following focal ischemia in diet induced ketotic rat brain
Michelle Puchowicz, Douglas Emancipator, Jorge Gamboa, Jose Valerio, Kui Xu, W D Lust and Joseph C LaManna
J Cereb Blood Flow Metab 25: S307-S307; doi:10.1038/sj.jcbfm.9591524.0307
Remote preconditioning protects the rodent brain from focal cerebral ischemia
Samit Malhotra, Manjeet Singh and Daniel M Rosenbaum
J Cereb Blood Flow Metab 25: S308-S308; doi:10.1038/sj.jcbfm.9591524.0308
Hypoxic preconditioning reduces expression of the cyclin dependent kinase 5 in the post-ischemic neurons
Svetlana Pundik, W David Lust, Jose Valerio, Michael Buczek, Randall D York and Karl Herrup
J Cereb Blood Flow Metab 25: S309-S309; doi:10.1038/sj.jcbfm.9591524.0309
Increased SIRT1 following repetitive hypoxic preconditioning: A mechanism for mediating long-term tolerance (LTT) to focal stroke in adult mouse brain
Yolanda M Rangel, Angela B Freie, Ronaldo S Perez, Ernesto R Gonzales, Tamer Altay, Allison Holt, Tae S Park and Jeffrey M Gidday
J Cereb Blood Flow Metab 25: S310-S310; doi:10.1038/sj.jcbfm.9591524.0310
Ischemic preconditioning and erythropoietin neuroprotection share common downstream pathways
Samit Malhotra, Lenore Ocave, Sean Savitz, Manjeet Singh and Daniel M Rosenbaum
J Cereb Blood Flow Metab 25: S311-S311; doi:10.1038/sj.jcbfm.9591524.0311
Hypoxic preconditioning increases expression of HIF prolyl hydroxylase 2 (Egln1) in neonatal rat brain
Nicole M Jones and Philip M Beart
J Cereb Blood Flow Metab 25: S312-S312; doi:10.1038/sj.jcbfm.9591524.0312
Carnosine is neuroprotective in a mouse model of stroke
Daniel Zemke, Rajanikant Krishnamurthy and Arshad Majid
J Cereb Blood Flow Metab 25: S313-S313; doi:10.1038/sj.jcbfm.9591524.0313
Experimental Ischemia: Therapy
Oral session
Oral session
Long-term effects of chronic statin treatment in the post-ischemic brain
Karen Gertz, Golo Kronenberg, Benjamin Winter, Juri Katchanov, Helmut Schröck, Georg Nickenig, Josef Priller, Ulrich Laufs and Matthias Endres
J Cereb Blood Flow Metab 25: S1-S1; doi:10.1038/sj.jcbfm.9591524.0001
Mitogen activated protein kinase inhibition attenuate cerebral blood flow reduction and abolish cerebral artery receptor upregulation after subarachnoid haemorrhage in rat
Saema Beg, Jacob Hansen-Schwartz and Lars Edvinsson
J Cereb Blood Flow Metab 25: S2-S2; doi:10.1038/sj.jcbfm.9591524.0002
Acute augmentation of cerebral blood flow by rho-kinase inhibitors in focal cerebral ischemia is dependent on endothelial nitric oxide synthase
Hwa Kyoung Shin, Andrew K Dunn, Phillip Jones, David A Boas, James K Liao, Michael A Moskowitz and Cenk Ayata
J Cereb Blood Flow Metab 25: S3-S3; doi:10.1038/sj.jcbfm.9591524.0003
The role of neuregulins in neuroprotection following acute stroke
Byron D Ford, Zhenfeng Xu, Gregory D Ford, Alicia Gates and Ju Jiang
J Cereb Blood Flow Metab 25: S4-S4; doi:10.1038/sj.jcbfm.9591524.0004
NIM811 prevents induction of mitochondrial permeability transition in cerebral ischemia
Amit S Korde, Peter Waldmeier, L Creed Pettigrew, Susan D Craddock and William F Maragos
J Cereb Blood Flow Metab 25: S5-S5; doi:10.1038/sj.jcbfm.9591524.0005
Neuroprotective effects of creatine in a mouse model of stroke: an experimental MRI study
Georg Royl, Konstantin Prass, Ute Lindauer, Dirk Megow, Ulrich Dirnagl and Josef Priller
J Cereb Blood Flow Metab 25: S6-S6; doi:10.1038/sj.jcbfm.9591524.0006
Oral session
Poster Session
Differential effects of oestrogen in models of permanent and transient focal cerebral ischaemia
Kirsty B Gordon, I Mhairi Macrae and Hilary V O Carswell
J Cereb Blood Flow Metab 25: S7-S7; doi:10.1038/sj.jcbfm.9591524.0007
Tumor necrosis factor-alpha neutralization reduced cerebral edema following transient focal cerebral ischemia
Naohisa Hosomi, Takayuki Naya and Masakazu Kohno
J Cereb Blood Flow Metab 25: S8-S8; doi:10.1038/sj.jcbfm.9591524.0008
Late post-ischemic intracerebral thrombin-application reduces infarct volume
Petra Henrich-Noack, Georg Reiser and Klaus G Reymann
J Cereb Blood Flow Metab 25: S9-S9; doi:10.1038/sj.jcbfm.9591524.0009
-Adrenoreceptor antagonists attenuate brain injury following transient focal ischemia in rats
Toru Goyagi, Tetsu Kimura and Toshiaki Nishikawa
J Cereb Blood Flow Metab 25: S10-S10; doi:10.1038/sj.jcbfm.9591524.0010
Neuroprotective and anti-apoptotic effects of FK506 following transient focal ischemia in rats
Shimon Amemiya, Tatsushi Kamiya, Toshiki Inaba, Masayuki Ueda, Kengo Kato, Chikako Nito, Satoshi Suda, Yasuhiro Nishiyama and Yasuo Katayama
J Cereb Blood Flow Metab 25: S11-S11; doi:10.1038/sj.jcbfm.9591524.0011
The importance of extracellular calcium for endothelin type A and B receptor-mediated contraction in rat basilar artery
Roya Jamali and Lars Edvinsson
J Cereb Blood Flow Metab 25: S12-S12; doi:10.1038/sj.jcbfm.9591524.0012
Alpha-linolenic acid and riluzole, activators of 2 pore-domain K+ channels afford brain protection against focal brain ischemia
Catherine Heurteaux, Christophe Laigle, Gisèle Jarretou, Michel Lazdunski and Nicolas Blondeau
J Cereb Blood Flow Metab 25: S13-S13; doi:10.1038/sj.jcbfm.9591524.0013
TNF-alpha and EGF potentiate the ETB receptor mediated contraction in rat middle cerebral arteries
Emelie Stenman, Marie Henriksson and Lars Edvinsson
J Cereb Blood Flow Metab 25: S14-S14; doi:10.1038/sj.jcbfm.9591524.0014
Differential effect of GlyT1 inhibitors on the development of ischemic cerebral infarction
Laszlo Szabo
J Cereb Blood Flow Metab 25: S15-S15; doi:10.1038/sj.jcbfm.9591524.0015
Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046
Feng Li, Takeshi Hayashi, Nobuhiko Omori, Guang Jin, Kentaro Deguchi, Shoko Nagotani, Hanzhe Zhang, Yoshihide Sehara, Xiquan Wang, Keiko Hamakawa, Isao Nagano, Mikio Shoji and Koji Abe
J Cereb Blood Flow Metab 25: S16-S16; doi:10.1038/sj.jcbfm.9591524.0016
Reduction of cerebral infarction in SHR-SP by statins
Shoko Nagotani, Takeshi Hayashi, Keiko Hamakawa, Guang Jin, Kentaro Deguchi, Yoshihide Sehara, HanZhe Zhang, XiQuan Wang, Isao Nagano, Mikio Shoji and Koji Abe
J Cereb Blood Flow Metab 25: S17-S17; doi:10.1038/sj.jcbfm.9591524.0017
The neuroprotective effects of a newly synthesized poly (ADP-ribose) polymerase (PARP) inhibitor (KCL-440) on neuronal cell death following transient focal ischemia in rat
Tatsushi Kamiya, Chikako Nito, Simon Amemiya, Masayuki Ueda, Kengo Kato, Yasuhiro Nishiyama, Satoshi Suda, Toshiki Inaba and Yasuo Katayama
J Cereb Blood Flow Metab 25: S18-S18; doi:10.1038/sj.jcbfm.9591524.0018
Thrombin generation and inhibition in the mediation of ischemic neuronal death
Marlise de Castro Ribeiro, Jerome Badaut, Melanie Price, Marita Meins, Julien Bogousslavsky, Denis Monard and Lorenz Hirt
J Cereb Blood Flow Metab 25: S19-S19; doi:10.1038/sj.jcbfm.9591524.0019
Prolonged therapeutic window associated with pharmacologic blockade of vascular adhesion protein-1 (VAP-1)-related post-ischemic leukocyte adhesion in diabetic, ovariectomized (OVX) female rats given chronic estrogen replacement
Dale A Pelligrino, Luisa Salter-Cid, Matthew D Linnik and Hao-Liang Xu
J Cereb Blood Flow Metab 25: S20-S20; doi:10.1038/sj.jcbfm.9591524.0020
Progesterone and allopregnanolone as neuroprotectants in ischemic ovariectomized mouse brain
Susan M Parker, Patricia D Hurn and Stephanie J Murphy
J Cereb Blood Flow Metab 25: S21-S21; doi:10.1038/sj.jcbfm.9591524.0021
Neuroprotective activity of glucocorticoids against NMDA toxicity in mouse cortical neuron-astrocyte cultures: Potential role of the tPA-PAI-1 axis
Edith Debroas, Carine Ali, Nathalie Lebeurrier, Denis Vivien and Dominic Duval
J Cereb Blood Flow Metab 25: S22-S22; doi:10.1038/sj.jcbfm.9591524.0022
Cilostazol protects both grey and white matter in a rodent model of permanent focal cerebral ischemia
Fumiaki Honda, Hideaki Imai, Chisato Kubota, Tatsuya Shimizu and Nobuhito Saito
J Cereb Blood Flow Metab 25: S23-S23; doi:10.1038/sj.jcbfm.9591524.0023
Atorvastatin reduces cerebral infarction via inhibiting NADPH oxidase-derived superoxide in transient focal ischemia
Hua Hong, Jin-Sheng Zeng, Yong-Yuan Guan and Alex F Chen
J Cereb Blood Flow Metab 25: S24-S24; doi:10.1038/sj.jcbfm.9591524.0024
Stroke protection by atorvastatin treatment in stroke-prone spontaneously hypertensive rats (SHRSPs):1. rate of morbidity and mortality of stroke, and serum asymmetric dimethyl arginine (ADMA)
Noriko Tanaka, Toshiya Katsumata, Tatsuo Otori, Yutaka Nishiyama, Hidenori Nakamura and Yasuo Katayama
J Cereb Blood Flow Metab 25: S25-S25; doi:10.1038/sj.jcbfm.9591524.0025
Mapping of glial metabolism in intact rat brain using 14C-acetate
Rie Hosoi, Yuto Kashiwagi, Shin-ichiro Hirose, Koji Abe, Jun Hatazawa, Antony Gee and Osamu Inoue
J Cereb Blood Flow Metab 25: S26-S26; doi:10.1038/sj.jcbfm.9591524.0026
Neuroprotective effects of dexmedetomidine-hypothermia after asphyxial cardiac arrest in rats
Tetsu Kimura, Toru Goyagi, Makoto Tanaka, Yoshitsugu Tobe, Yoko Masaki and Toshiaki Nishikawa
J Cereb Blood Flow Metab 25: S27-S27; doi:10.1038/sj.jcbfm.9591524.0027
Hyperglycemia increases protein kinase C (PKC) activity and myogenic tone of penetrating brain parenchymal arterioles and is associated with diminished postischemic reperfusion and enhanced infarction
Marilyn J Cipolla, Lisa Vitullo, Nicole Hoyniak and Rachael Hannah
J Cereb Blood Flow Metab 25: S28-S28; doi:10.1038/sj.jcbfm.9591524.0028
Protective effect of minocycline treatment on striatal ischemia in rats
Huijin Yan, Richard Buist, Dale Corbett and James Peeling
J Cereb Blood Flow Metab 25: S29-S29; doi:10.1038/sj.jcbfm.9591524.0029
Protective effect of the free radical scavenger (edaravone) against the photochemically induced cerebral infarction in the mice
Shinji Nakajima, Syoujiroh Sawada, Yuhji Morimoto and Souichiroh Nomura
J Cereb Blood Flow Metab 25: S30-S30; doi:10.1038/sj.jcbfm.9591524.0030
3-methyl-phenyl-2-pyrazolin-5-one (Edaravone), a novel free radical scavenger: Edaravone inhibits the increase of plasma OxLDL and S100B in patients with acute cortical infarction
Atsuhiko Suzue, Masaaki Uno, Keiko T Kitazato, Kazuhito Matsuzaki, Hiroyuki Itabe and Shinji Nagahiro
J Cereb Blood Flow Metab 25: S31-S31; doi:10.1038/sj.jcbfm.9591524.0031
A substance P antagonist improves outcome following reversible middle cerebral artery occlusion in rats
Renee J Turner, Peter C Blumbergs and Robert Vink
J Cereb Blood Flow Metab 25: S32-S32; doi:10.1038/sj.jcbfm.9591524.0032
Do cyclosporin A and insulin synergistically protect against ischemic spinal cord injury in rabbits?
Shyunsuke Tsuruta, Mishiya Matsumoto, Yumika Koizumi, Shiro Fukuda and Takefumi Sakabe
J Cereb Blood Flow Metab 25: S33-S33; doi:10.1038/sj.jcbfm.9591524.0033
Pretreatment with angiotensin type II receptor blocker candesartan reduces superoxide production and subsequent ischemic neuronal injury after global cerebral ischemia
Taku Sugawara, Hiroyuki Kinouchi, Masaya Oda, Hidehiko Shoji, Tomoya Omae, Suguru Yamaguchi and Kazuo Mizoi
J Cereb Blood Flow Metab 25: S34-S34; doi:10.1038/sj.jcbfm.9591524.0034
Influence of anaesthesia on the neuroprotective effect elicited by 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, in a mouse model of transient focal cerebral ischemia
Jérôme Couturier, Elisabeth Letellier, Bruno Palmier, Michel Plotkine and Isabelle Margaill
J Cereb Blood Flow Metab 25: S35-S35; doi:10.1038/sj.jcbfm.9591524.0035
Temporary cerebral ischaemia upregulates the 5-HT1 receptor in the middle cereral artery
Jacob Hansen-Schwartz, Flemming F Johansen and Lars Edvinsson
J Cereb Blood Flow Metab 25: S36-S36; doi:10.1038/sj.jcbfm.9591524.0036
Mechanisms of neuroprotection by acetyl-L-carnitine
Nina J Solenski, Gary M Fiskum, Santina A Zanelli and Robert E Rosenthal
J Cereb Blood Flow Metab 25: S37-S37; doi:10.1038/sj.jcbfm.9591524.0037
Velcade®, a first-in-class proteasome inhibitor, is efficacious in rat permanent middle cerebral artery occlusion
Nancy E Stagliano, JingMei Ren, William Riordan and Seth P Finklestein
J Cereb Blood Flow Metab 25: S38-S38; doi:10.1038/sj.jcbfm.9591524.0038
Increased activation of NF-kB and ERK1/2 after permanent focal ischemia is abolished by simvastatin pre-treatment
Mauro Cimino, Cristina Banfi, Maura Brioschi, Paolo Gelosa, Elena Nobili, Anita Gianella, Elena Tremoli and Luigi Sironi
J Cereb Blood Flow Metab 25: S39-S39; doi:10.1038/sj.jcbfm.9591524.0039
Upregulation of contractile ETB receptors in middle cerebral arteries is dependent on PKC
Marie Henriksson, Emelie Stenman and Lars Edvinsson
J Cereb Blood Flow Metab 25: S40-S40; doi:10.1038/sj.jcbfm.9591524.0040
Neuroprotective effect of STAZN in focal cerebral ischemia: a therapeutic-window study
Ludmila Belayev, Larissa Khoutorova, Alexey Vigdorchik, Jim J Ley, David A Becker, Weizhao Zhao, Raul Busto and Myron D Ginsberg
J Cereb Blood Flow Metab 25: S41-S41; doi:10.1038/sj.jcbfm.9591524.0041
Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic failure, and neuronal death
Robert E Rosenthal, Viktoria Vereczki, Erica M Martin and Gary Fiskum
J Cereb Blood Flow Metab 25: S42-S42; doi:10.1038/sj.jcbfm.9591524.0042
Deferoxamine reduces CSF free iron levels following intracerebral hemorrhage in rats
Shu Wan, Guohua Xi, Richard Keep, Julian Hoff and Ya Hua
J Cereb Blood Flow Metab 25: S43-S43; doi:10.1038/sj.jcbfm.9591524.0043
Effect of erythropoietin on neonatal hypoxia-ischemia encephalopathy
Changlian Zhu, Wenqing Kang, Xiaoyang Wang, Hong Xiong and Xiuyong Cheng
J Cereb Blood Flow Metab 25: S44-S44; doi:10.1038/sj.jcbfm.9591524.0044
Peripheral administration of interleukin-1 receptor antagonist (IL-1ra) reduces ischaemic brain damage in the rat
Simon R Clark, Allan Stuart and Rothwell J Nancy
J Cereb Blood Flow Metab 25: S45-S45; doi:10.1038/sj.jcbfm.9591524.0045
Plasma kallikrein inhibitor DX-88 protects against brain ischemia/reperfusion injury
Emanuela Rossi, Claudio Storini, Diana Maiocchi, Maria Grazia De Simoni and Luigi Bergamaschini
J Cereb Blood Flow Metab 25: S46-S46; doi:10.1038/sj.jcbfm.9591524.0046
C1-inhibitor protects against brain ischemia/reperfusion injury via inhibition of cell recruitment and inflammation
Claudio Storini, Emanuela Rossi, Veronica Marrella, Luigi Bergamaschini and MariaGrazia De Simoni
J Cereb Blood Flow Metab 25: S47-S47; doi:10.1038/sj.jcbfm.9591524.0047
Peroxisome proliferator-activated receptor alpha activation promotes neurological recovery and exerts anti-edematous effect in a model of traumatic brain injury
Valerie C Besson, Xiaoru R Chen, Michel Plotkine and Catherine Marchand-Verrecchia
J Cereb Blood Flow Metab 25: S48-S48; doi:10.1038/sj.jcbfm.9591524.0048
Effect of three inducible NOS inhibitors on cerebral edema formation and neurological deficit in a rat model of traumatic brain injury
Gaëlle Louin, Catherine Marchand-Verrecchia, Bruno Palmier, Michel Plotkine and Mehrnaz Jafarian-Tehrani
J Cereb Blood Flow Metab 25: S49-S49; doi:10.1038/sj.jcbfm.9591524.0049
Delayed administration of deferoxamine reduces brain infarction and improves functional recovery after transient focal cerebral ischemia in the rat
Thomas Freret, Samuel Valable, Laurent Chalzaviel, Eric T MacKenzie, Edwige Petit, Myriam Bernaudin, Michel Boulouard and Pascale Schumann-Bard
J Cereb Blood Flow Metab 25: S50-S50; doi:10.1038/sj.jcbfm.9591524.0050
Role of Akt1 in estrogen-mediated neuroprotection
Nabil J Alkayed, Staphanie J Murphy, Sharon M Graham and Patrica D Hurn
J Cereb Blood Flow Metab 25: S51-S51; doi:10.1038/sj.jcbfm.9591524.0051
Effect of nuclear factor-kappa B on cell survival of SOD1 TG astrocytes after oxygen glucose deprivation
Yong-Sun Lee, Yun Seon Song, Jian Wang, Rona G Giffard and Pak H Chan
J Cereb Blood Flow Metab 25: S52-S52; doi:10.1038/sj.jcbfm.9591524.0052
Roles of the C-terminal peptide binding domain of human inducible HSP70 in focal ischemic brain injury
Yunjuan Sun, Yibing Ouyang, Lijun Xu and Rona G Giffard
J Cereb Blood Flow Metab 25: S53-S53; doi:10.1038/sj.jcbfm.9591524.0053
Neuroprotective effects of diketopiperazines, potential clinical application of small cyclic form of neuropeptide following ischemic brain injury
Jian Guan, Sam Mathai, Frank Sieg, Thorsten Gorba, Margaret Brimble and Peter Gluckman
J Cereb Blood Flow Metab 25: S54-S54; doi:10.1038/sj.jcbfm.9591524.0054
Antioxidant protective effects of stobadine against ischemia/reperfusion (I/R) induced alterations of muscular and endothelial functions of rat middle cerebral arteries (MCA)
Michèle Bastide, Olivier Pétrault, Maud Laprais, Thavarak Ouk, Svorad Stolc and Régis Bordet
J Cereb Blood Flow Metab 25: S55-S55; doi:10.1038/sj.jcbfm.9591524.0055
Acute treatment by a PPAR- agonist decreases cerebral infarct volume and prevents post-ischemic endothelium and Kir 2.1 impairment
Thavarak Ouk, Olivier Pétrault, Sophie Gautier, Patrick Gelé, Maud Laprais, Patrick Duriez, Michèle Bastide and Régis Bordet
J Cereb Blood Flow Metab 25: S56-S56; doi:10.1038/sj.jcbfm.9591524.0056
Time-lag combination therapy for cerebral ischemia using the FNK protein transduction technology and an immunosuppressant, I: In vivo study
Ken-ichiro Kasura, Megumi Watanabe, Kumiko Takahashi, Genki Mizukoshi, Seiji Ohkubo, Hironaka Igarashi, Takashi Mori, Sadamitsu Asoh, Shigeo Ohta and Yasuo Katayama
J Cereb Blood Flow Metab 25: S57-S57; doi:10.1038/sj.jcbfm.9591524.0057
Time-lag combination therapy for cerebral ischemia using the FNK protein transduction technology and an immunosuppressant, II: In vitro study
Megumi Watanabe, Ken-ichiro Katsura, Genki Mizukoshi, Ikuroh Ohsawa, Sadamitsu Asoh, Shigeo Ohta and Yasuo Katayama
J Cereb Blood Flow Metab 25: S58-S58; doi:10.1038/sj.jcbfm.9591524.0058
Stroke protection by atorvastatin treatment in stroke-prone spontaneously hypertensive rats (SHRSPs): 2. Measurement of regional cerebral blood flow (RCBF) by autoradiography
Tatsuo Otori, Toshiya Katsumata, Noriko Tanaka, Yutaka Nishiyama, Hidenori Nakamura and Yasuo Katayama
J Cereb Blood Flow Metab 25: S59-S59; doi:10.1038/sj.jcbfm.9591524.0059
Experimental Models and Methods
Oral session
CBF imaging and global CBF quantification in normal rats using dedicated pinhole SPECT system
Philippe Choquet, Vincent Israel-Jost, Izzie J Namer, Pascal Bilbault, François Schneider and André Constantinesco
J Cereb Blood Flow Metab 25: S527-S527; doi:10.1038/sj.jcbfm.9591524.0527
Effect of edaravone on hyper-accumulation around the lesion by 18F-FDG PET in primate thromboembolic stroke
Tetsuya Yoshikawa, Teruo Susumu, Yuki Akiyoshi, Koichiro Fukuzaki, Ryoichi Nagata, Yasukatsu Izumi, Yasuhiro Wada, Yasuyoshi Watanabe, Hiroshi Iwao and Go Kito
J Cereb Blood Flow Metab 25: S528-S528; doi:10.1038/sj.jcbfm.9591524.0528
New model of focal cerebral ischemia in the miniature pig
Hideaki Imai, Kenjiro Konno, Mitsunobu Nakamura, Tatsuya Shimizu, Chisato Kubota, Koji Seki, Fumiaki Honda, Shinichiro Tomizawa, Yukitaka Tanaka, Hidekazu Hata and Nobuhito Saito
J Cereb Blood Flow Metab 25: S529-S529; doi:10.1038/sj.jcbfm.9591524.0529
A simple and standardized mouse model of cerebral ischemia-hypoxia
Faisal Adhami, Guanghong Liao, Aryn Schloemer, Frank Sharp and Chia-Yi Kuan
J Cereb Blood Flow Metab 25: S530-S530; doi:10.1038/sj.jcbfm.9591524.0530
Endovascular dilation of rat carotid artery by ultraviolet laser light transmitted by microcatheterized optical fiber
Brant D Watson, Ricardo Prado, Adelfa Morales and John Rose
J Cereb Blood Flow Metab 25: S531-S531; doi:10.1038/sj.jcbfm.9591524.0531
Considerations in the selection of behavioural tests to gauge recovery after intracerebral hemorrhagic stroke in rats
Crystal MacLellan, Angela Auriat, Steven McGie, Reginia Yan, Maxine DeButte and Frederick Colbourne
J Cereb Blood Flow Metab 25: S532-S532; doi:10.1038/sj.jcbfm.9591524.0532
Hyperactive and anxious phenotype following brief ischemic episodes in mice
Benjamin Winter, Georg Juckel, Mustafa Balkaya, Heide Hörtnagl and Matthias Endres
J Cereb Blood Flow Metab 25: S533-S533; doi:10.1038/sj.jcbfm.9591524.0533
Characterisation of the neocortical clip model of focal cerebral ischaemia by MRI, neurological assessment, behaviour and immunohistochemistry
Maria Ashioti, John S Beech, Andrew S Lowe, Mike Modo, Mayke Hesselink and Steve C R Williams
J Cereb Blood Flow Metab 25: S534-S534; doi:10.1038/sj.jcbfm.9591524.0534
Selective and reversible occlusion of the middle cerebral artery in rats by an intraluminal approach
Jianya Ma and Thaddeus S Nowak Jr
J Cereb Blood Flow Metab 25: S535-S535; doi:10.1038/sj.jcbfm.9591524.0535
Altered cerebrovascular control in response to hypertension in a novel transgenic rat model of malignant hypertension
Paul A T Kelly, Linda Ferrington and John J Mullins
J Cereb Blood Flow Metab 25: S536-S536; doi:10.1038/sj.jcbfm.9591524.0536
Cerebrovascular pressure transmission: Changes in highest modal frequency induced by vasodilation
Michael L Daley, Massroor Pourcyrous, Shelly D Timmons and Charles W Leffler
J Cereb Blood Flow Metab 25: S537-S537; doi:10.1038/sj.jcbfm.9591524.0537
Spatio-temporal dynamics of infarct evolution using MR-based prediction algorithms
Ona Wu, Toshihisa Sumii, Masao Sasamata, Bruce R Rosen, Eng H Lo and Rick M Dijkhuizen
J Cereb Blood Flow Metab 25: S538-S538; doi:10.1038/sj.jcbfm.9591524.0538
Unilateral proximal occlusion of the middle cerebral artery has no effect on acquisition or retention of spatial memory
Deborah Bingham, Stephen J Martin, I Mhairi Macrae, Richard G M Morris and Hilary V O Carswell
J Cereb Blood Flow Metab 25: S539-S539; doi:10.1038/sj.jcbfm.9591524.0539
Correlation of infarct volume with functional outcome in an embolic MCA occlusion model in rats
Max Nedelmann, Thomas Wilhelm-Schwenkmezger, Beat Alessandri, Axel Heimann, Felicitas Schneider, B Martin Eicke, Marianne Dieterich and Oliver Kempski
J Cereb Blood Flow Metab 25: S540-S540; doi:10.1038/sj.jcbfm.9591524.0540
Software (KEIO-IS2) for automatically tracking red blood cells (RBCs) with calculation of individual RBC velocities in single capillaries of rat brain
Istvan Schiszler, Hidetaka Takeda, Minoru Tomita, Yutaka Tomita, Takashi Osada, Miyuki Unekawa, Norio Tanahashi and Norihiro Suzuki
J Cereb Blood Flow Metab 25: S541-S541; doi:10.1038/sj.jcbfm.9591524.0541
An improved technique for silicone-coating the suture used in rat MCA occlusion increases stroke induction rate, reduces mortality, and is effective across a wide weight and age range
Neil J Spratt, John A C Fernandez, Michelle Chen, Sarah S J Rewell, Susan F Cox, Leena van Raay, Lisa Hogan and David W Howells
J Cereb Blood Flow Metab 25: S542-S542; doi:10.1038/sj.jcbfm.9591524.0542
A new technique for the mapping of oxygen tension on the brain surface
Satoshi Kimura, Keigo Matsumoto, Yoshio Imahori, Katsuyoshi Mineura and Toshiyuki Itoh
J Cereb Blood Flow Metab 25: S543-S543; doi:10.1038/sj.jcbfm.9591524.0543
Brain venous hypertension induces angiogenesis through overexpression of hypoxia-inducible factor-1 (HIF-1)
Yiqian Zhu, Fanxia Shen, Yongmei Chen, William L Young and Guo-Yuan Yang
J Cereb Blood Flow Metab 25: S544-S544; doi:10.1038/sj.jcbfm.9591524.0544
White matter injury in kaolin-induced neonatal rat hydrocephalus
Osaama H Khan and Marc R Del Bigio
J Cereb Blood Flow Metab 25: S545-S545; doi:10.1038/sj.jcbfm.9591524.0545
Isometric force measurement in mouse cerebral arteries: establishing reference values and characterizing functional consequences of endothelial nitric oxide synthase knock-out in the basilar artery
Armin Hilpert, Zoltan Benyo and Lothar Schilling
J Cereb Blood Flow Metab 25: S546-S546; doi:10.1038/sj.jcbfm.9591524.0546
Cortical microflow quantitative measurements with high spatial and temporal resolution over 1 month after focal cerebral ischemia in mice
Yutaka Tomita, Alexy Tran Dinh, Istvan Schiszler, Minoru Tomita, Norihiro Suzuki, Nathalie Kubis, Elisabeth Pinard and Jacques Seylaz
J Cereb Blood Flow Metab 25: S547-S547; doi:10.1038/sj.jcbfm.9591524.0547
Application of NIRS in mice: Assessing cerebral blood flow and cerebral autoregulation
Helga Blockx, Geofrey De Visscher and Willem Flameng
J Cereb Blood Flow Metab 25: S548-S548; doi:10.1038/sj.jcbfm.9591524.0548
FK506 extended therapeutic time windows of thrombolysis without increasing risk of hemorrhagic transformation on embolic rat
Seiji Okubo, Hironaka Igarashi, Tomoyuki Kanamatsu and Yasuo Katayama
J Cereb Blood Flow Metab 25: S549-S549; doi:10.1038/sj.jcbfm.9591524.0549
Rheoencephalographic evidence of complement activation-related cerebrovascular changes in pigs
Michael Bodo, Janos Szebeni, Lajos Baranyi, Sandor Savay, Frederick Pearce, Carl Alving and Rolf Bunger
J Cereb Blood Flow Metab 25: S550-S550; doi:10.1038/sj.jcbfm.9591524.0550
Use of rheoencephalography for primary stroke prevention
Michael Bodo, Gyorgy Thuroczy, Mike Bodo Jr, Tamas Nebella, Gyula Panczel, Kornel Sipos, Peter Bonoczk, Zoltan Nagy and Andras Javor
J Cereb Blood Flow Metab 25: S551-S551; doi:10.1038/sj.jcbfm.9591524.0551
Image analysis of immunohistopathology from micro- to macro-scale: Application to ischemic brain tissue
Chunyan Wu, Weizhao Zhao, Baowan Lin and Myron Ginsberg
J Cereb Blood Flow Metab 25: S552-S552; doi:10.1038/sj.jcbfm.9591524.0552
Alteration of oxygen metabolism in MCA occlusion rat model by positron emission tomography with injectable O-15-oxygen
Yasuhiro Magata, Takashi Temma, Mikako Ogawa, Takahiro Mukai, Hidekazu Kawashima, Yuji Kuge, Hiroshi Watabe, Hidehiro Iida and Hideo Saji
J Cereb Blood Flow Metab 25: S553-S553; doi:10.1038/sj.jcbfm.9591524.0553
A lentivirus-based model to study the selective activation of delta and epsilon PKC during ischemia and ischemic preconditioning
Jesus Purroy, Ami Raval, Eun Joo Kim and Miguel A Perez-Pinzon
J Cereb Blood Flow Metab 25: S554-S554; doi:10.1038/sj.jcbfm.9591524.0554
Changes in cerebral blood flow modalities during hemorrhage in rats
Michael Bodo, Frederick Pearce, Lajos Baranyi and Rocco Armonda
J Cereb Blood Flow Metab 25: S555-S555; doi:10.1038/sj.jcbfm.9591524.0555
Reactivity of non-pressurized, non-perfused cerebral arterioles
Leonid Groysman, Greg Miekisiak, Alexander Beylin, David Kung and H Richard Winn
J Cereb Blood Flow Metab 25: S556-S556; doi:10.1038/sj.jcbfm.9591524.0556
Loss of distensibility in cerebral arteries with chronic hypertension and vasospasm after subarachnoid hemorrhage
Takeshi Kondoh, Seiji Nakajima, Akitsugu Morishita, Haruo Yamashita, Eiji Kohmura, Takashi Sakurai, Kohichi Yokono and Keiji Umetani
J Cereb Blood Flow Metab 25: S557-S557; doi:10.1038/sj.jcbfm.9591524.0557
Synchrotron radiation X-rays demonstrate small cerebral vessels in normal mouse and variations under ischemia in rat
Masahiro Tamaki, Takashi Mizobe, Keiji Kidoguchi, Junnji Koyama, Takeshi Kondoh, Haruo Yamashita, Takashi Sakurai, Kohichi Yokono and Keiji Umetani
J Cereb Blood Flow Metab 25: S558-S558; doi:10.1038/sj.jcbfm.9591524.0558
Towards a routine analysis of anatomical and functional post mortem slices in 3 dimensions
Julien Dauguet, Albertine Dubois, Anne-Sophie Hérard, Laurent Besret, Gilles Bonvento, Philippe Hantraye and Thierry Delzescaux
J Cereb Blood Flow Metab 25: S559-S559; doi:10.1038/sj.jcbfm.9591524.0559
Gene Expression and Cell Therapy
Oral session
Oral session
Migration and morphology changes of bone marrow cells in ischemic and peri-ischemic areas of the mouse brain demonstrated by chronic in vivo imaging
Alexy Tran Dinh, Nathalie Kubis, Yutaka Tomita, Bartosz Karaszewski, Yolande Calando, Karim Oudina, Hervé Petite, Jacques Seylaz and Elisabeth Pinard
J Cereb Blood Flow Metab 25: S494-S494; doi:10.1038/sj.jcbfm.9591524.0494
Nestin-expressing cells divide and adopt a complex electrophysiological phenotype after transient brain ischemia
Golo D Kronenberg, Wang Li Ping, Michael Synowitz, Karen Gertz, Juri Katchanov, Rainer Glass, Christoph Harms, Gerd Kempermann, Helmut Kettenmann and Matthias Endres
J Cereb Blood Flow Metab 25: S495-S495; doi:10.1038/sj.jcbfm.9591524.0495
The consequences of herpes simplex virus (HSV) vector delivery of GADD34 on focal ischaemia in the mouse
F White, C McCabe, S M Brown, J Harland and I M Macrae
J Cereb Blood Flow Metab 25: S496-S496; doi:10.1038/sj.jcbfm.9591524.0496
Assessing the effects of a contrast agent on the ability of neural stem cell grafts to recover behavioural impairments in a rat model of stroke: A 1 year serial MRI study
Michel Modo, Cori Smee, John S Beech, Maria Ashioti, Thomas J Meade, Jack Price and Steve C R Williams
J Cereb Blood Flow Metab 25: S497-S497; doi:10.1038/sj.jcbfm.9591524.0497
Stabilization of hypoxia-inducible factor 1 in neural stem cells with prolyl hydroxylase inhibition induces delayed tolerance against focal cerebral ischemia
Kon Chu, Soon-Tae Lee, Keun-Hwa Jung, Seung U Kim, Manho Kim and Jae-Kyu Roh
J Cereb Blood Flow Metab 25: S498-S498; doi:10.1038/sj.jcbfm.9591524.0498
Oral session
Poster Session
Aggravation of ischemic brain injury by prion protein deficiency, but lack of neuroprotection by elevated prion protein levels: Role of tyrosine kinases
Annett Spudich, Rico Frigg, Ertugrul Kilic, Ülkan Kilic, Bruno Oesch, Alex Raeber, Claudio L Bassetti and Dirk M Hermann
J Cereb Blood Flow Metab 25: S499-S499; doi:10.1038/sj.jcbfm.9591524.0499
Neuropilin-1 is a molecular target of the transcription factor E2F1 and is involved in cerebral ischemia–induced neuronal death
Sheng T Hou, Susan X Jiang, Melissa Sheldrick and Angele Desbois
J Cereb Blood Flow Metab 25: S500-S500; doi:10.1038/sj.jcbfm.9591524.0500
Effect of bone marrow transplantation of cytosolic phospholipase A2 deficient mice in focal cerebral ischemia/reperfusion injury
Sadaharu Tabuchi, Yasutaka Yamamoto, Takashi Watanabe, Naonori Uozumi and Takao Shimizu
J Cereb Blood Flow Metab 25: S501-S501; doi:10.1038/sj.jcbfm.9591524.0501
Influence of growth factors on proliferation and DCX doublestaining after transient focal cerebral ischemia
Kathrin Baldauf, Petra Henrich-Noack and Klaus G Reymann
J Cereb Blood Flow Metab 25: S502-S502; doi:10.1038/sj.jcbfm.9591524.0502
Serial and simultaneous PET measurement of fetal nigral transplantation in hemi-Parkinson model rats with [11C]PE2I and [11C]raclopride
Motoki Inaji, Takahito Yoshizaki, Kiyoshi Ando, Jun Maeda, Takashi Okauchi, Shigeru Obayashi, Tetsuya Suhara, Hideyuki Okano, Tadashi Nariai and Kikuo Ohno
J Cereb Blood Flow Metab 25: S503-S503; doi:10.1038/sj.jcbfm.9591524.0503
Deficiency of PAR-2 gene increases acute focal ischemic brain injury
Guang Jin, Takeshi Hayashi, Junichi Kawagoe, Toshiaki Takizawa, Tetsuya Nagata, Isao Nagano, Mikio Shoji and Koji Abe
J Cereb Blood Flow Metab 25: S504-S504; doi:10.1038/sj.jcbfm.9591524.0504
Neuroprotective effect of antisense oligodeoxynucleotides in experimental intracerebral hemorrhage in rats
Huijin Yan, Mengzhou Xue, Christopher Power, Marc R Del-Bigio and James Peeling
J Cereb Blood Flow Metab 25: S505-S505; doi:10.1038/sj.jcbfm.9591524.0505
Peroxisome proliferator-activated receptor-
activation as a mechanism of preventive neuroprotection induced by pioglitazone treatment
Kimihiko Hattori, Tomokazu Shimazu, Ikuo Inoue, Nobuo Araki, Shigehiro Katayama, Kunio Shimazu and Joel H Greenberg
J Cereb Blood Flow Metab 25: S506-S506; doi:10.1038/sj.jcbfm.9591524.0506
Post-ischemic gene transfer of IL-10 protects against global brain ischemia
Takashi Shichita, Hiroaki Ooboshi, Yasuhiro Kumai, Masahiro Kumai, Junichi Takada, Takanari Kitazono, Setsuro Ibayashi and Mitsuo Iida
J Cereb Blood Flow Metab 25: S507-S507; doi:10.1038/sj.jcbfm.9591524.0507
Heat shock protein overexpression - effect on experimental stroke
Louise van der Weerd, Mark F Lythgoe, Romina Aron Badin, Jackie de Belleroche, David L Latchman and David G Gadian
J Cereb Blood Flow Metab 25: S508-S508; doi:10.1038/sj.jcbfm.9591524.0508
Gene therapy for stroke using viral delivery of heat schock proteins
Romina Aron Badin, Mark F Lythgoe, Louise van der Weerd, David L Thomas, David L Latchman and David G Gadian
J Cereb Blood Flow Metab 25: S509-S509; doi:10.1038/sj.jcbfm.9591524.0509
MR cellular imaging of magnetically labeled neural stem cells in a dysmyelinated mouse brain model
Piotr Walczak, Dorota Kedziorek, Assaf A Gilad and Jeff W M Bulte
J Cereb Blood Flow Metab 25: S510-S510; doi:10.1038/sj.jcbfm.9591524.0510
Trafficking of human neural stem cells is regulated by stromal cell-derived factor-1 / CXC- chemokine receptor 4 signaling
Kon Chu, Soon-Tae Lee, Keun-Hwa Jung, Seung U Kim, Manho Kim and Jae-Kyu Roh
J Cereb Blood Flow Metab 25: S511-S511; doi:10.1038/sj.jcbfm.9591524.0511
Stem cell visualization in the rat brain by an improved MRI protocol
Uwe Himmelreich, Pedro Ramos-Cabrer, Ralph Weber, Susanne Wegener and Mathias Hoehn
J Cereb Blood Flow Metab 25: S512-S512; doi:10.1038/sj.jcbfm.9591524.0512
ONO-5046 attenuates delayed motor neuron death and affects the induction of BDNF, p-ERK and caspase3 after spinal cord ischemia in rabbits
Takashi Yamauchi, Masahiro Sakurai, Yoshiki Sawa, Koji Abe and Hikaru Matsuda
J Cereb Blood Flow Metab 25: S513-S513; doi:10.1038/sj.jcbfm.9591524.0513
Comparative evaluation of three superparamagnetic iron oxide nanoparticles, feridex, MION-47, and tat-CLIO, to label human neural stem cells
Miyeoun Song, Yunhee Kim, Woo Kyung Moon and Byung-Woo Yoon
J Cereb Blood Flow Metab 25: S514-S514; doi:10.1038/sj.jcbfm.9591524.0514
Time-dependent systematic migration of intravenously transplanted human neural stem cells in ischemic rats
Miyeoun Song, Sun Ryu, Youngju Kim, Yunhee Kim and Byung-Woo Yoon
J Cereb Blood Flow Metab 25: S515-S515; doi:10.1038/sj.jcbfm.9591524.0515
Focal cerebral ischemia increases type 2 iodothyronine deiodinase
Koji Seki, Hideaki Imai, Tatsuya Shimizu, Katsuhiko Tsunekawa, Takayuki Kasahara, Takayuki Ogiwara, Nobuhito Saito and Masami Murakami
J Cereb Blood Flow Metab 25: S516-S516; doi:10.1038/sj.jcbfm.9591524.0516
Transplanted stem cells undergo cellular fusion in experimental brain trauma
Zsombor Lacza, Eszter M Horváth, Attila Csordás, Márk Kollai, Csaba Szabó and David W Busija
J Cereb Blood Flow Metab 25: S517-S517; doi:10.1038/sj.jcbfm.9591524.0517
Chronic survival and function of adult stem cells from adipose tissue in the ischemic mouse brain
Nathalie Kubis, Yutaka Tomita, Valérie Planat, Alexy Tran Dinh, Yolande Calando, Monique André, Ludovic Waekel, Bartosz Karaszewski, Luc Pénicaud, Bernard I Lévy, Jean-Sébastien Silvestre, Louis Casteilla, Jacques Seylaz and Elisabeth Pinard
J Cereb Blood Flow Metab 25: S518-S518; doi:10.1038/sj.jcbfm.9591524.0518
Traumatic brain injury coupled with secondary hypoxia leads to a mild endoplasmic reticulum stress response in the rat
Jessie S Truettner, Bingren Hu, Ofelia F Alonso, Helen M Bramlett and W Dalton Dietrich
J Cereb Blood Flow Metab 25: S519-S519; doi:10.1038/sj.jcbfm.9591524.0519
Gene expression in human cerebral arteries
Petter Vikman and Lars Edvinsson
J Cereb Blood Flow Metab 25: S520-S520; doi:10.1038/sj.jcbfm.9591524.0520
Neural stem cells decrease neuronal loss induced by ischemia/reperfusion in mice
Carmen Capone, Simona Frigerio, Alessia Cafici, Chiara Carlesso, Simone Pizzimenti, Maurizio Gelati, Giulio Alessandri, Eugenio Parati and MariaGrazia De Simoni
J Cereb Blood Flow Metab 25: S521-S521; doi:10.1038/sj.jcbfm.9591524.0521
Expression profiling in the photothrombotic rat model: Identification of genes potentially involved in plasticity
Wolf-R Schäbitz, Carola Krüger, Domus Cira, Clemens Sommer and Armin Schneider
J Cereb Blood Flow Metab 25: S522-S522; doi:10.1038/sj.jcbfm.9591524.0522
Spatio-temporal profile of small heat-shock protein Hsp27 induction in rat brain following fluid-percussion injury to the lateral parietotemporal cerebral cortex; involvement with beta actin
Jae-Hyuk Yi, Raquel Herrero, Chun-lei Wang and Alan Stewart Hazell
J Cereb Blood Flow Metab 25: S523-S523; doi:10.1038/sj.jcbfm.9591524.0523
Vasculogenesis, angiogenesis and local blood flow recovery after embryonic stem cells transplantation in the ischemic brain
Ling Wei, Jianan Wang, Michelle Hedrick, Chang-ling Li, Christine L Keogh, David I Gottlieb and Shan Ping Yu
J Cereb Blood Flow Metab 25: S524-S524; doi:10.1038/sj.jcbfm.9591524.0524
MRI investigation of angiogenesis after neuronal progenitor cell therapy of stroke
Quan Jiang, Zheng Gang Zhang, Guang Liang Ding, Li Zhang, Lian Li, Rui Lan Zhang, Lei Wang, He Meng, James R Ewing, Qing Jiang Li, Robert A Knight and Michael Chopp
J Cereb Blood Flow Metab 25: S525-S525; doi:10.1038/sj.jcbfm.9591524.0525
Magnetic labeling of human neural progenitor cells for in vivo MRI migration analysis following transplantation in stroke
Raphael Guzman, Bliss Tonya, Uchida Nobuko, Greve Joan, Sun Guo Hua, Palmer Theo, Moseley Mike and Steinberg Gary
J Cereb Blood Flow Metab 25: S526-S526; doi:10.1038/sj.jcbfm.9591524.0526
Mechanisms of Cell Death
Oral session
Oral session
Role of glycine in ischemic neuronal injury -the study using functional knockout mice of glycine cleavege enzyme
Masaya Oda, Hiroyuki Kinouchi, Shigeo Kure, Taku Sugawara, Suguru Yamaguchi, Kenichi Sato, Yoichi Matsubara, Tomoya Omae and Kazuo Mizoi
J Cereb Blood Flow Metab 25: S422-S422; doi:10.1038/sj.jcbfm.9591524.0422
Normobaric hyperoxia therapy exerts its neuroprotective effect through an increase in tissue pO2 and a decrease in free radical generation, caspases and MMP expression in the ischemic penumbra
Shimin Liu, Wenlan Liu, Wei Ding, Honglian Shi, Gary A Rosenberg and Ke J Liu
J Cereb Blood Flow Metab 25: S423-S423; doi:10.1038/sj.jcbfm.9591524.0423
EP1 receptors are responsible for COX-2 mediated neurotoxicity
Josef Anrather, Ping Zhou, Takayuki Kawano, Liping Qian, Camile Gooden and Costantino Iadecola
J Cereb Blood Flow Metab 25: S424-S424; doi:10.1038/sj.jcbfm.9591524.0424
Negative neurovascular coupling during anoxic depolarization and peri-infarct spreading depressions in acute focal cerebral ischemia in mice
Cenk Ayata, Hwa Kyoung Shin, Phillip Jones, Andrew K Dunn, David A Boas and Michael A Moskowitz
J Cereb Blood Flow Metab 25: S425-S425; doi:10.1038/sj.jcbfm.9591524.0425
Metabolic substrates prevent PARP1-mediated mitochondrial dysfunction and cell death
Conrad C Alano, Weihai Ying and Raymond A Swanson
J Cereb Blood Flow Metab 25: S426-S426; doi:10.1038/sj.jcbfm.9591524.0426
Detection of cortical spreading depression and peri-infarct depolarisations in the injured human brain
Martin Fabricius, Susanne Fuhr, Robin Bhatia, Martyn Boutelle, Parastoo Hashemi, Anthony J Strong and Martin Lauritzen
J Cereb Blood Flow Metab 25: S427-S427; doi:10.1038/sj.jcbfm.9591524.0427
Oral session
Poster Session
Cytoplasmic, mitochondrial or ER stress response after transient cerebral ischemia
Chunli Liu, Jessie Truttner, Shaoyi Chen, Dalton Dietrich, Helen Bramlett and Bingren Hu
J Cereb Blood Flow Metab 25: S428-S428; doi:10.1038/sj.jcbfm.9591524.0428
Superoxide causes endoplasmic reticulum damage and activates apoptotic machinery in ischemic neurons
Takeshi Hayashi, Pak H Chan, Guang Jin, Kentaro Deguchi, Shoko Nagotani, Yoshihide Sehara, Hanzhe Zhang, Xiquan Wang, Isao Nagano, Mikio Shoji and Koji Abe
J Cereb Blood Flow Metab 25: S429-S429; doi:10.1038/sj.jcbfm.9591524.0429
Diabetes mellitus causes astrocyte damage after ischemia and reperfusion injury
Pingan Li, Chaonan Ding, Marianna Muranyi, Qingping He and Yanling Lin
J Cereb Blood Flow Metab 25: S430-S430; doi:10.1038/sj.jcbfm.9591524.0430
Subunit-specific effects of NMDA receptor signaling: Implications for stroke
Yitao Liu, Tak Pan Wong, Michelle Aarts, Lidong Liu, Dongchuan Wu, Jie Lu, Michael Tymianski and Yu-Tian Wang
J Cereb Blood Flow Metab 25: S431-S431; doi:10.1038/sj.jcbfm.9591524.0431
Electrocorticographic evidence of deteriorating penumbral conditions associated with delayed peri-infarct depolarizations following reperfusion in rat focal cerebral ischemia
Jed A Hartings, Michael L Rolli and Frank C Tortella
J Cereb Blood Flow Metab 25: S432-S432; doi:10.1038/sj.jcbfm.9591524.0432
Acute amyloid-beta, cerebral penetrating arterioles and oxygen radical
Hans H Dietrich
J Cereb Blood Flow Metab 25: S433-S433; doi:10.1038/sj.jcbfm.9591524.0433
Does tissue plasminogen activator mediate neurogeneneration in the 1-methyl-4-phenyl-1, 2, 3, 6- tetrahydropyridine (MPTP) mouse model of Parkinson's disease?
Gabriel T Liberatore, Swee Jin Mok, Kate Sidon and David W Howells
J Cereb Blood Flow Metab 25: S434-S434; doi:10.1038/sj.jcbfm.9591524.0434
Production of nitric oxide in a diabetic animal model (OLETF) during forebrain ischemia and reperfusion
Tomokazu Shimazu, Nobuo Araki, Tsuyoshi Ohkubo, Yoshio Asano, Masahiko Sawada, Daisuke Furuya, Harumitsu Nagoya, Masamizu Yamazato, Yasuo Ito, Yuji Kato and Kunio Shimazu
J Cereb Blood Flow Metab 25: S435-S435; doi:10.1038/sj.jcbfm.9591524.0435
Seizure-induced neuronal necrosis with internucleosomal DNA cleavage is caspase-independent
Denson G Fujikawa, Rosen B Trinidad and Xingrao Ke
J Cereb Blood Flow Metab 25: S436-S436; doi:10.1038/sj.jcbfm.9591524.0436
Endoplasmic reticulum stress induced by spinal cord ischemia in rabbits: Induction of Grp78 and caspase12 in motor neurons
Masahiro Sakurai, Koji Abe, Yasuto Itoyama and Koichi Tabayashi
J Cereb Blood Flow Metab 25: S437-S437; doi:10.1038/sj.jcbfm.9591524.0437
Spreading depression (SD) waves in the brainstem can be elicited after blockade of potassium channels – evidence for the role of extracellular potassium ions as a driving force?
Frank Richter, Alfred Lehmenkühler and Hans-Georg Schaible
J Cereb Blood Flow Metab 25: S438-S438; doi:10.1038/sj.jcbfm.9591524.0438
Effects of isoflurane on the ischemia-induced release of excitatory amino acids, brain swelling and injury in a model of transient ischemia in rats
Marie-Françoise Ritz, Petra Schmidt and Aminadav Mendelowitsch
J Cereb Blood Flow Metab 25: S439-S439; doi:10.1038/sj.jcbfm.9591524.0439
Concentration dependent effects of estrogen and progestins on cell death in cortical cultures
Doug Lobner, Julie Hjelmhaug and Abed K Salous
J Cereb Blood Flow Metab 25: S440-S440; doi:10.1038/sj.jcbfm.9591524.0440
Mitochondrial translocation of P53 following transient global ischemia in rats
Hidenori Endo, Hiroshi Kamada, Chikako Nito, Tatsuro Nishi and Pak H Chan
J Cereb Blood Flow Metab 25: S441-S441; doi:10.1038/sj.jcbfm.9591524.0441
Increased oxidative biomarker in plasma reflects the cerebral oxidative damage in rats
Keiko T Kitazato, Hao Liu, Masaaki Uno, Atsuhiko Suzue, Kyoko Nishi, Shinji Manabe, Hiroyuki Yamasaki, Yuichi Takahashi, Hiroyuki Itabe and Shinji Nagahiro
J Cereb Blood Flow Metab 25: S442-S442; doi:10.1038/sj.jcbfm.9591524.0442
AMPA but not NMDA receptor stimulation induces an exacerbated brain lesion in spontaneously hypertensive rats
Clotilde Leblond, Julien Chuquet, Eric T MacKenzie and Omar Touzani
J Cereb Blood Flow Metab 25: S443-S443; doi:10.1038/sj.jcbfm.9591524.0443
Oxygen treatment after perinatal hypoxia-ischemia reduces neuronal damage at short survival times, but worsens injury with long-term survival
Kristin M Noppens, J Regino Perez-Polo, David K Rassin, Karin N Westlund, Roderic Fabian, Thomas A Kent and Marjorie R Grafe
J Cereb Blood Flow Metab 25: S444-S444; doi:10.1038/sj.jcbfm.9591524.0444
Differential role of synaptic an extrasynaptic NMDA receptors in glutamate mediated neuronal injury
Fréderic Léveillé, Olivier Nicole, Eric MacKenzie and Alain Buisson
J Cereb Blood Flow Metab 25: S445-S445; doi:10.1038/sj.jcbfm.9591524.0445
Further evidence for the role of inositol trisphosphate as an excitotoxic death signal in hippocampal neurons
S Yamamoto, K Ibaraki, T Tsuboi, T Sakurai and S Terakawa
J Cereb Blood Flow Metab 25: S446-S446; doi:10.1038/sj.jcbfm.9591524.0446
Poly-ADP-ribosylation is a prevalent post-translational modification of mitochondrial proteins in the brain
Yi-Chen Lai, Yamming Chen, Xiaopeng Zhang, Paula D Nathaniel, Fengli Guo, Larry W Jenkins, Simon C Watkins, Patrick M Kochanek, Csaba Szabo and Robert S B Clark
J Cereb Blood Flow Metab 25: S447-S447; doi:10.1038/sj.jcbfm.9591524.0447
Peri-infarct depolarisations are a cause as well as an effect of cortical ischaemia in the gyrencephalic brain
Anthony J Strong, Peter J B Anderson, Helena R Watts, David J Virley, Andrew P Lloyd, Toshiaki Nagafuji and Mitsuyoshi Ninomiya
J Cereb Blood Flow Metab 25: S448-S448; doi:10.1038/sj.jcbfm.9591524.0448
Effects of natural anthraquinones on neuronal survival in rat brain neuron
Hsin-Hsueh Lee, Yi-Hsuan Lee and Ling-Ling Yang
J Cereb Blood Flow Metab 25: S449-S449; doi:10.1038/sj.jcbfm.9591524.0449
Survival of newborn neurons in the adult hippocampus is enhanced by Bcl-2 overexpression in normal and ischemic conditions
Tsutomu Sasaki, Kazuo Kitagawa, Yoshiki Yagita, Emi Omura-Matsuoka, Shiro Sugiura, Kenichi Todo, Kohji Matsushita and Masatsugu Hori
J Cereb Blood Flow Metab 25: S450-S450; doi:10.1038/sj.jcbfm.9591524.0450
Effects of candesartan on NO production in aged spontaneous hypertensive rat during global cerebral ischemia and reperfusion
Harumitsu Nagoya, Nobuo Araki, Tsuyoshi Ohkubo, Yoshio Asano, Masahiko Sawada, Daisuke Furuya, Kimihiko Hattori, Tomokazu Shimazu, Masamizu Yamazato, Yasuo Ito, Yuji Kato, Mikiko Ninomiya and Kunio Shimazu
J Cereb Blood Flow Metab 25: S451-S451; doi:10.1038/sj.jcbfm.9591524.0451
Effects of HBO with reduction of iNOS and HIF -1 in motor neurons after transient spinal cord ischemia in rabbits
Noritaka Murakami, Masahiro Sakurai, Takashi Horinouchi, Jun Ito, Shin Kurosawa and Masato Kato
J Cereb Blood Flow Metab 25: S452-S452; doi:10.1038/sj.jcbfm.9591524.0452
Effect of edaravone, a novel free radical scavenger, on nitric oxide production and nNOS activity during cerebral ischemia and reperfusion in mice
Takeshi Ohkubo, Nobuo Araki, Yoshio Asano, Masahiko Sawada, Daisuke Furuya, Tomokazu Shimazu, Harumitsu Nagoya, Masamizu Yamazato, Yasuo Ito, Yuji Kato, Mikiko Ninomiya, Keisuke Ishizawa, Takanori Hirose and Kunio Shimazu
J Cereb Blood Flow Metab 25: S453-S453; doi:10.1038/sj.jcbfm.9591524.0453
The N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 does not block spreading ischemia in the rat
Jens P Dreier, Olaf Windmüller, Gabor C Petzold, Karl M Einhäupl, Ute Lindauer, Uwe Heinemann and Ulrich Dirnagl
J Cereb Blood Flow Metab 25: S454-S454; doi:10.1038/sj.jcbfm.9591524.0454
Neuroprotective activity of neuroserpin against NMDA receptor-mediated excitotoxicity
Nathalie Lebeurrier, Géraldine Liot, Jose-Pascual Lopez-Atalaya, Monica Fernandez-Monreal, Peter Sonderegger, Denis Vivien and Carine Ali
J Cereb Blood Flow Metab 25: S455-S455; doi:10.1038/sj.jcbfm.9591524.0455
Glutamate receptor subunit 2 (GluR2) expression mediates protection conferred to CA1 neurons from ischemic damage by prior fimbria-fornix deafferentation
Jaspreet Kaur, Zonghang Zhao, Rose M Geransar, Ping Sun and Alastair M Buchan
J Cereb Blood Flow Metab 25: S456-S456; doi:10.1038/sj.jcbfm.9591524.0456
Characterizing the evolution of the ischemic penumbra using pH weighted imaging
Phillip Z Sun, Jinyuan Zhou, Weiyun Weiyun, Judy Huang and Peter C M van Zijl
J Cereb Blood Flow Metab 25: S457-S457; doi:10.1038/sj.jcbfm.9591524.0457
Central role of neuronal IkappaBalpha kinase (IKK) in cerebral ischemia
Oliver Herrmann, Rossanna de Lorenzi, Sajjad Muhammad, Wen Zhang, Martin Koehrmann, Ioana Potrovita, Ira Maegele, Cordian Beyer, James R Burke, Thomas Wirth, Manolis Pasparakis, Bernd Baumann and Markus Schwaninger
J Cereb Blood Flow Metab 25: S458-S458; doi:10.1038/sj.jcbfm.9591524.0458
Inhibition of nitric oxide synthase does not prevent phosphorylation of the alpha subunit of eukaryotic initiation factor two following brain ischemia and reperfusion
Heather L Montie and Donald J DeGracia
J Cereb Blood Flow Metab 25: S459-S459; doi:10.1038/sj.jcbfm.9591524.0459
In vivo PPAR activation attenuates cerebrovascular endothelial dysfunction via impeding NADPH oxidase-derived superoxide and augmenting tetrahydrobiopterin in mineralocorticoid hypertension
Lixin Li, Song-Jie Liao, Li Lin, Jin-Sheng Zeng and Alex F Chen
J Cereb Blood Flow Metab 25: S460-S460; doi:10.1038/sj.jcbfm.9591524.0460
Endocytosis and autophagy in cerebral ischemia and excitotoxicity
Anne Vaslin, Julien Puyal, Vanessa Waechter, Tiziana Borsello and Peter G H Clarke
J Cereb Blood Flow Metab 25: S461-S461; doi:10.1038/sj.jcbfm.9591524.0461
Application of in vivo esr spectroscopy to measurement of cerebrovascular ROS generation in stroke
Mayumi Yamato, Toshiaki Watanabe and Hideo Utsumi
J Cereb Blood Flow Metab 25: S462-S462; doi:10.1038/sj.jcbfm.9591524.0462
Assessment of stress granules in motor cortex following global brain ischemia and reperfusion
Foaz Kayali, Heather L Montie, Jose A Rafols and Donald J DeGracia
J Cereb Blood Flow Metab 25: S463-S463; doi:10.1038/sj.jcbfm.9591524.0463
Evolution of focal cerebral ischaemia in rats observed by optical intrinsic signals imaging
Shangbin Chen, Zhe Feng, Pengcheng Li, Shaoqun Zeng and Qingming Luo
J Cereb Blood Flow Metab 25: S464-S464; doi:10.1038/sj.jcbfm.9591524.0464
Contribution of hemodynamics and light scattering to the changes in optical intrinsic signal during cortical spreading depression in rats
Pengcheng Li, Yuanyaun Yang and Qingming Luo
J Cereb Blood Flow Metab 25: S465-S465; doi:10.1038/sj.jcbfm.9591524.0465
Apoptosis inducing factor (AIF) is essential for neuronal cell death following transient focal cerebral ischemia
Carsten Culmsee, Changlian Zhu, Miriam Höhn, Stefan Landshamer, Uta Mamrak, Klas Blomgren and Nikolaus Plesnila
J Cereb Blood Flow Metab 25: S466-S466; doi:10.1038/sj.jcbfm.9591524.0466
ROS generation is ameliorated by ischemic preconditioning in organotypic hippocampal slice cultures
Robert Dugger, Ami P Raval and Miguel A Pérez-Pinzón
J Cereb Blood Flow Metab 25: S467-S467; doi:10.1038/sj.jcbfm.9591524.0467
Sigma receptors mediate potent neuroprotection in vivo and inhibit neuronal depolarisation and swelling in rat brain slices
Jennifer K Callaway, Christine Molnar, Song T Yao, Bevyn Jarrott and R David Andrew
J Cereb Blood Flow Metab 25: S468-S468; doi:10.1038/sj.jcbfm.9591524.0468
Mutant ubiquitin accumulate in CA1 pyramidal cells after transient global ischemia in gerbil
Kazuo Yamashiro, Takao Urabe, Nobutaka Hattori and Yoshikuni Mizuno
J Cereb Blood Flow Metab 25: S469-S469; doi:10.1038/sj.jcbfm.9591524.0469
Increased extracellular potassium concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression in human and rat brain slices
Gabor C Petzold, Stephan Haack, Dirk Megow, Katharina Buchheim, Uwe Heinemann, Ulrich Dirnagl and Jens P Dreier
J Cereb Blood Flow Metab 25: S470-S470; doi:10.1038/sj.jcbfm.9591524.0470
Hypothermia decreases the protein levels of TNF family members and their signaling intermediates after traumatic brain injury
George Lotocki, Robert W Keane, Ofelia F Alonso and W Dalton Dietrich
J Cereb Blood Flow Metab 25: S471-S471; doi:10.1038/sj.jcbfm.9591524.0471
PI-3/AKT kinase pathway contributes to neuroprotective effect of hypothermia against cerebral ischemia in rats
Heng Zhao, Takayoshi Shimohata, Jade Q Wang, Guohua Sun, David W Schaal, Robert M Sapolsky and Gary K Steinberg
J Cereb Blood Flow Metab 25: S472-S472; doi:10.1038/sj.jcbfm.9591524.0472
Alterations of intracranial pressure may lead to secondary deterioration by inducing peri-infarct depolarizations
Masao Umegaki, Yannic Waerzeggers, Yasuhiro Sanada, Gerhard Rosner, Christian Dohmen, Wolf-Dieter Heiss and Rudolf Graf
J Cereb Blood Flow Metab 25: S473-S473; doi:10.1038/sj.jcbfm.9591524.0473
Conditions of protection by hypothermia and effects on apoptotic pathways in a model of permanent middle cerebral artery occlusion
Heng Zhao, Jade Q Wang, Guohua Sun, Midori A Yenari, Robert M Sapolsky and Gary K Steinberg
J Cereb Blood Flow Metab 25: S474-S474; doi:10.1038/sj.jcbfm.9591524.0474
Significance of protein histidine phosphatase for neuronal viability
Susanne Klumpp, Anette Mäurer, Daniela Faber, Martina Lehmann, Gunther Bechmann, Thomas Wieland, Susanne Lutz, Thomas Gudermann, Olaf Pinkenburg and Josef Krieglstein
J Cereb Blood Flow Metab 25: S475-S475; doi:10.1038/sj.jcbfm.9591524.0475
Activation of an early and novel ASK1-MKK4-JNK signaling pathway after focal cerebral ischemia in rats
Hiroshi Kamada, Chikako Nito, Hidenori Endo, Tatsuro Nishi and Pak H Chan
J Cereb Blood Flow Metab 25: S476-S476; doi:10.1038/sj.jcbfm.9591524.0476
Effect of PPAR gamma agonist on cerebral nitric oxide production during cerebral ischemia and reperfusion
M Yamazato, N Araki, T Ohkubo, Y Asano, M Sawada, D Furuya, K Hattori, T Shimazu, H Nagoya, Y Ito, Y Kato, M Ninomiya and K Shimazu
J Cereb Blood Flow Metab 25: S477-S477; doi:10.1038/sj.jcbfm.9591524.0477
Cholinergic thalamic excitation results in remote caspase-independent cell damage and seizures
Angelique Regnier, Jasleen Shant, Sima Mraovitch, Betty Chen, Eric Vicaut and Eugene Golanov
J Cereb Blood Flow Metab 25: S478-S478; doi:10.1038/sj.jcbfm.9591524.0478
Lipid rafts mediate Fas apoptotic signaling after spinal cord injury
Angela R Davis, Jessie S Truettner, Alex E Marcillo, W Dalton Dietrich and Robert W Keane
J Cereb Blood Flow Metab 25: S479-S479; doi:10.1038/sj.jcbfm.9591524.0479
Caspase-dependent mechanisms are involved in delayed cell death in a rat model with critically reduced cerebral blood flow
Axel Heimann, Sylvia Hartmann, Beat Alessandri and Oliver Kempski
J Cereb Blood Flow Metab 25: S480-S480; doi:10.1038/sj.jcbfm.9591524.0480
Erythropoietin induces neuroprotection in experimental intracerebral hemorrhage via eNOS upregulation and STAT3 activation
Soon-Tae Lee, Kon Chu, Manho Kim and Jae-kyu Roh
J Cereb Blood Flow Metab 25: S481-S481; doi:10.1038/sj.jcbfm.9591524.0481
The protective effect of lipophilic iron chelator 2, 2'-dipyridyl after focal cerebral ischemia closely correlates with limitation of apoptotic cell death
Michaël C Van Hoecke, Anne Prigent-Tessier, Philippe E Garnier, Christine Marie and Alain Beley
J Cereb Blood Flow Metab 25: S482-S482; doi:10.1038/sj.jcbfm.9591524.0482
Mechanisms of vascular reactivity during cortical spreading depression (CSD) and cortical spreading ischemia (CSI)
Ute Lindauer, Ulrich Dirnagl and Jens P Dreier
J Cereb Blood Flow Metab 25: S483-S483; doi:10.1038/sj.jcbfm.9591524.0483
Null mutation of P53 attenuates hippocampal neuronal death in vivo following global ischemia in mice
Ichiro Yonekura, Nobutaka Kawahara, Akio Asai and Takaaki Kirino
J Cereb Blood Flow Metab 25: S484-S484; doi:10.1038/sj.jcbfm.9591524.0484
NMDA modulates the phosphorylation of several translation factors and inhibits protein synthesis in neural cultures
Valerie Petegnief, M Elena Martin, Matilde Salinas and Anna M Planas
J Cereb Blood Flow Metab 25: S485-S485; doi:10.1038/sj.jcbfm.9591524.0485
Mild hypothermia inhibits Fas expression and caspase-8 activation following experimental stroke
Jong Youl Kim, Liping Liu, Danye Cheng, Maya Koike, Francis Blankenberg, Jong Eun Lee and Midori A Yenari
J Cereb Blood Flow Metab 25: S486-S486; doi:10.1038/sj.jcbfm.9591524.0486
Neuroprotection against ischemic CA1 neurodegeneration by pituitary adenylate cyclase activating polypeptide via cAMP-response-element-binding protein-mediated enhancement of endogenous DNA repair
Wenjin Li, Yumin Luo, Masanori Iwai, Yanqin Gao, Guodong Cao and Jun Chen
J Cereb Blood Flow Metab 25: S487-S487; doi:10.1038/sj.jcbfm.9591524.0487
Simultaneous multimodal optical imaging of cerebral blood flow and oxygenation in focal ischemic core and penumbra in mice
Hwa Kyoung Shin, Phillip Jones, Andrew K Dunn, David A Boas, Michael A Moskowitz and Cenk Ayata
J Cereb Blood Flow Metab 25: S488-S488; doi:10.1038/sj.jcbfm.9591524.0488
Free radical generation is involved in hypoglycemia-induced neuronal death
Sang Won Suh, Koji Aoyama, Elizabeth Gum and Raymond A Swanson
J Cereb Blood Flow Metab 25: S489-S489; doi:10.1038/sj.jcbfm.9591524.0489
Redistribution of apoptosis promoters: XAF1, Smac/DIABLO and HtrA2 during transient forebrain ischemia/reperfusion
Abdelhaq Rami and Markus David Siegelin
J Cereb Blood Flow Metab 25: S490-S490; doi:10.1038/sj.jcbfm.9591524.0490
Spreading depolarizations in human traumatic brain injury
Jed A Hartings, Anna T Mazzeo, Martin Fabricius, Frank C Tortella and M Ross Bullock
J Cereb Blood Flow Metab 25: S491-S491; doi:10.1038/sj.jcbfm.9591524.0491
Nitric oxide production during cerebral ischemia and reperfusion in endothelial nitric oxide synthase knockout mice
Yasuo Ito, Nobuo Araki, Takeshi Ohkubo, Yosio Asano, Masahiko Sawada, Daisuke Furuya, Kimihiko Hattori, Tomokazu Shimazu, Harumitsu Nagoya, Masakiyo Yamazato, Yuji Kato, Mikiko Ninomiya and Kunio Shimazu
J Cereb Blood Flow Metab 25: S492-S492; doi:10.1038/sj.jcbfm.9591524.0492
Nitric oxide production during cerebral ischemia and reperfusion in neuronal nitric oxide synthase knockout mice
Y Kato, N Araki, T Ohkubo, Y Asano, M Sawada, D Furuya, K Hattori, T Shimazu, M Yamazato, H Nagoya, Y Ito, M Ninomiya and K Shimazu
J Cereb Blood Flow Metab 25: S493-S493; doi:10.1038/sj.jcbfm.9591524.0493
Neuroimaging
Oral session
Oral session
Changes in cerebral blood flow and cerebral oxygen metabolism during neural activation measured by positron emission tomography: Comparison with changes in blood oxygenation level-dependent contrast measured by functional magnetic resonance imaging
Hiroshi Ito, Masanobu Ibaraki, Iwao Kanno, Hiroshi Fukuda and Shuichi Miura
J Cereb Blood Flow Metab 25: S314-S314; doi:10.1038/sj.jcbfm.9591524.0314
Mechanisms of deep brain stimulation in obsessive-compulsive disorder revealed by 15O-H2O PET and diffusion tractography
J C Klein, D Lennartz, J Poggenborg, K Herholz, K Lackner, V Sturm and W D Heiss
J Cereb Blood Flow Metab 25: S315-S315; doi:10.1038/sj.jcbfm.9591524.0315
Impact of sleep deprivation on cerebral A1 adenosine receptor (A1AR) density: A PET study
David Elmenhorst, Philipp T Meyer, Andreas Matusch, Karl Zilles and Andreas Bauer
J Cereb Blood Flow Metab 25: S316-S316; doi:10.1038/sj.jcbfm.9591524.0316
15O-PET shows that cerebral blood volume is increased in head injury, but may still not be the dominant cause of intracranial hypertension
David K Menon, Jonathan P Coles, Tim D Fryer, Dot A Chatfield, Luzius A Steiner, Andrew J Johnston, Franklin I Aigbirhio, John C Clark and John D Pickard
J Cereb Blood Flow Metab 25: S317-S317; doi:10.1038/sj.jcbfm.9591524.0317
Assessment of microglial activation in patients with Alzheimer's disease using [C-11]-(R)-PK11195 and PET
Alie Schuitemaker, Bart N M van Berckel, Ronald Boellaard, Marc A Kropholler, Cees Jonker, Dick J Veltman, Philip Scheltens and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S318-S318; doi:10.1038/sj.jcbfm.9591524.0318
Effects of early rearing condition on the central serotonin system: [11C]DASB PET imaging of serotonin transporters in adolescent peer- and mother-reared rhesus monkeys
Masanori Ichise, Douglass C Vines, Tami Gura, Stephen J Suomi, J Dee Higley and Robert B Innis
J Cereb Blood Flow Metab 25: S319-S319; doi:10.1038/sj.jcbfm.9591524.0319
Resolution and inversion time dependence of CBF measurements using MRI: A possible explanation for discrepancy between MRI and PET
Manus J Donahue, Craig K Jones, Hanzhang Lu and Peter C M van Zijl
J Cereb Blood Flow Metab 25: S320-S320; doi:10.1038/sj.jcbfm.9591524.0320
Quantitative assessment of the cerebral nicotinic acetylcholine receptors (nAChR) in Parkinson's disease using 2-[18F]F-A-85380-PET
Philipp Meyer, Kai Kendziorra, Swen Hesse, Henryk Barthel, Georg Becker, Dietlind Sorger, Andreas Schildan, Marianne Patt, Anita Seese, Gudrun Wagenknecht, Donald Lobsien, Florian Then Bergh, Peter Brust, Jörg Steinbach, Claus Zimmer, Johannes Schwarz and Osama Sabri
J Cereb Blood Flow Metab 25: S321-S321; doi:10.1038/sj.jcbfm.9591524.0321
Mood changes in women with premenstrual dysphoria correlate to changes in brain serotonin precursor trapping (11C-5-hydroxy-L-tryptophan)
Olle Eriksson, Anders Wall, Ina Marteinsdottir, Hans Ågren, Per Hartvig, Gunnar Blomqvist, Bengt Långström and Tord Naessén
J Cereb Blood Flow Metab 25: S322-S322; doi:10.1038/sj.jcbfm.9591524.0322
Spatiotemporal evolution of functional hemodynamic changes and their relationship to neuronal activity
Sameer Sheth, Michael Guiou and Arthur W Toga
J Cereb Blood Flow Metab 25: S324-S324; doi:10.1038/sj.jcbfm.9591524.0324
PET imaging of 5-HT1A receptors in late-life depression: Relationship to treatment response
Carolyn C Meltzer, Julie C Price, Scott K Ziolko, Chester A Mathis, Lisa A Weissfeld, Patricia R Houck, Brian J Lopresti, Benoit H Mulsant and Charles F Reynolds
J Cereb Blood Flow Metab 25: S323-S323; doi:10.1038/sj.jcbfm.9591524.0323
Cerebral GABA decrease in patients with schizophrenia measured by 1 H MR chemical shift imaging of GABA
In-Young Choi, Sang-Pil Lee, Jun Shen and Daniel C Javitt
J Cereb Blood Flow Metab 25: S325-S325; doi:10.1038/sj.jcbfm.9591524.0325
Relative CBF estimation from the kinetics of hyperpolarized Xe-129 NMR spectroscopy
Kazuhiro Nakamura, Jeff Kershaw, Atsushi Wakai, Yasushi Kondoh, Hiroshi Sato, Naoyuki Takei and Iwao Kanno
J Cereb Blood Flow Metab 25: S326-S326; doi:10.1038/sj.jcbfm.9591524.0326
Oral session
Poster Session
Crossed cerebellar diaschisis in acute human stroke: A PET study of serial changes and response to supratentorial reperfusion by intravenous thrombolysis
Jan Sobesky, Alexander Thiel, Karl Herholz, Jobst Rudolf and Wolf-Dieter Heiss
J Cereb Blood Flow Metab 25: S327-S327; doi:10.1038/sj.jcbfm.9591524.0327
Signal to concentration proportionality constants for dynamic contrast T2* MRI cerebral blood volume measurements
George C Newman, Frank E Hospod, Howard A Rowley, Kari A Pulfer and Sean B Fain
J Cereb Blood Flow Metab 25: S328-S328; doi:10.1038/sj.jcbfm.9591524.0328
Modulation of motor memory formation by levodopa in healthy subjects and in chronic stroke patients: A study with 11C-raclopride PET
Agnes Floel, Gaetan Garraux, Peter Herscovitch, Stefan Knecht and Leonardo G Cohen
J Cereb Blood Flow Metab 25: S329-S329; doi:10.1038/sj.jcbfm.9591524.0329
Normal database of cerebral blood flow measured by SPECT with I-123-IMP, Tc-99m-HMPAO, and Tc-99m-ECD and PET with O-15 labeled water in humans: Comparison with voxel-based morphometry
Hiroshi Ito, Kentaro Inoue, Ryoi Goto, Ken Okada, Shigeo Kinomura, Yasuyuki Taki, Kazunori Sato, Tachio Sato, Iwao Kanno and Hiroshi Fukuda
J Cereb Blood Flow Metab 25: S330-S330; doi:10.1038/sj.jcbfm.9591524.0330
Transfer rate index as a new parameter of [201Tl]-SPECT in brain tumors
Yoshihiro Tohyama
J Cereb Blood Flow Metab 25: S331-S331; doi:10.1038/sj.jcbfm.9591524.0331
Correlation of FDG accumulation in the frontal cortex with fractional anisotropy in the frontal white matter fiber tracts
Kentaro Inoue, Hiroshi Ito, Shigeo Kinomura, Ken Okada, Masatoshi Ito and Hiroshi Fukuda
J Cereb Blood Flow Metab 25: S332-S332; doi:10.1038/sj.jcbfm.9591524.0332
Changes in thalamic blood flow caused by subthalamic deep brain stimulation in Parkinson's disease
Kenichi Yamamoto, Atsushi Umemura and Kazuo Yamada
J Cereb Blood Flow Metab 25: S333-S333; doi:10.1038/sj.jcbfm.9591524.0333
Dependence of the hemodynamic response to functional activation on the CO2-induced vasodilation
Bojana Stefanovic, Jan M Warnking, Karin M Rylander and G Bruce Pike
J Cereb Blood Flow Metab 25: S334-S334; doi:10.1038/sj.jcbfm.9591524.0334
The spatial dependence of the post-stimulus undershoot as revealed by high resolution bold and CBV weighted fMRI
Essa Yacoub, Kamil Ugurbil and Noam Harel
J Cereb Blood Flow Metab 25: S335-S335; doi:10.1038/sj.jcbfm.9591524.0335
The intra and inter-subject reproducibility of rodent olfactory bulb activity maps measured with fMRI
James R A Schafer, Ikuhiro Kida, Fuqiang Xu, Douglas Rothman and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S336-S336; doi:10.1038/sj.jcbfm.9591524.0336
Standardized CBF-SPECT imaging on EC-IC bypass surgery for hemodynamic cerebral ischemia
Jyoji Nakagawara, Hidehiro Iida, Sunao Mizumura, Toshiaki Osato, Kenji Kamiyama and Hidehiko Nakamura
J Cereb Blood Flow Metab 25: S337-S337; doi:10.1038/sj.jcbfm.9591524.0337
Voxel-based morphometry (VBM) analysis in Alzheimer's disease an insight into heterogeneity of cerebral atrophy
Akihiko Shiino, Toshiyuki Watanabe, Ichiro Akiguchi, Shigehiro Morikawa, Toshiro Inubushi and Masayuki Matsuda
J Cereb Blood Flow Metab 25: S338-S338; doi:10.1038/sj.jcbfm.9591524.0338
Quantitative tomographic evaluation of cerebral perfusion with perfusion weighted magnetic resonance imaging in the patients with moyamoya disease
Yoji Tanaka, Tadashi Nariai, Tsukasa Nagaoka, Kiichi Ishiwata, Michio Senda and Kikuo Ohno
J Cereb Blood Flow Metab 25: S339-S339; doi:10.1038/sj.jcbfm.9591524.0339
Methylphenidate-induced changes in regional cerebral blood flow: A [15O]H2O PET study in healthy volunteers
Joanna I Udo de Haes, Paul Maguire, Anne M J Paans, Piet L Jager and Johan A den Boer
J Cereb Blood Flow Metab 25: S340-S340; doi:10.1038/sj.jcbfm.9591524.0340
Cause of increase in signal intensity in T1-weighted images in the striatal region after global ischemia
Yoshimasa Takeda, Hisami Aoe and Kiyoshi Morita
J Cereb Blood Flow Metab 25: S341-S341; doi:10.1038/sj.jcbfm.9591524.0341
Cerebrovascular collaterals and misery perfusion in patients with middle cerebral artery occlusion: A combined study with PET and angiography
Makiko Tanaka, Rishu Piao, Naohiko Oku, Yasuyuki Kimura, Katsufumi Kajimoto, Hiroki Kato, Kazuo Kitagawa, Masatsugu Hori and Jun Hatazawa
J Cereb Blood Flow Metab 25: S342-S342; doi:10.1038/sj.jcbfm.9591524.0342
A comparison of FAIR and CASL perfusion imaging in mice
Louise van der Weerd, David L Thomas, Mark F Lythgoe and David G Gadian
J Cereb Blood Flow Metab 25: S343-S343; doi:10.1038/sj.jcbfm.9591524.0343
Serotonin synthesis is lower in the cortical areas of female than male healthy participants as measured with -[11C]methyl-L-tryptophan positron emission tomography
Mirko Diksic, Yojiro Sakai, Masami Nishikawa, Marco Leyton, Chawki Benkelfat and Simon N Young
J Cereb Blood Flow Metab 25: S344-S344; doi:10.1038/sj.jcbfm.9591524.0344
Brain metabolic fluctuations in absence of stimuli
Masaki Fukunaga, Silvina Horovitz, Peter van Gelderen, Jacco A de Zwart and Jozef H Duyn
J Cereb Blood Flow Metab 25: S345-S345; doi:10.1038/sj.jcbfm.9591524.0345
Changes in benzodiazepine receptor binding in Dutch veterans with posttraumatic stress disorder assessed with [C-11]-flumazenil and PET
Elbert Geuze, Bart N M van Berckel, Ronald Boellaard, Bert D Windhorst, Gert Luurtsema, Herman G M Westenberg, Adriaan A Lammertsma and Eric Vermetten
J Cereb Blood Flow Metab 25: S346-S346; doi:10.1038/sj.jcbfm.9591524.0346
Neuropathological features underlying different degrees of MRI signal intensity changes during reperfusion after transient focal ischemia in the rat
Anna M Planas, Abraham Martín, Santiago Rojas, Carles Falcón, Noelia Montoya, Núria Bargalló and Angel Chamorro
J Cereb Blood Flow Metab 25: S347-S347; doi:10.1038/sj.jcbfm.9591524.0347
Elucidating the functional actions of ketamine in the rat brain using locomotor, phMRI and microdialysis techniques
Clare L Littlewood, Nicholas Jones, Stephen N Mitchell, Michael J O'Neill and Steven C R Williams
J Cereb Blood Flow Metab 25: S348-S348; doi:10.1038/sj.jcbfm.9591524.0348
Regional but not global cerebral baseline blood flow differences are present in HIV associated dementia (HAD) using continuous arterial spin labeling
Beau M Ances, Anne C Roc, Dennis Kolson, Joyce Okawa, John Stern and John A Detre
J Cereb Blood Flow Metab 25: S349-S349; doi:10.1038/sj.jcbfm.9591524.0349
2D CSI H1 MR spectroscopy of cerebral metabolites in HIV associated dementia (HAD)
Beau M Ances, Anne C Roc, Sanjeev Chawla, Harish Poptani and John A Detre
J Cereb Blood Flow Metab 25: S350-S350; doi:10.1038/sj.jcbfm.9591524.0350
Misery perfusion accelerates selective neuronal loss in patients with steno-occlusive cerebrovascular diseases
Eku Shimosegawa, Masanobu Ibaraki, Shigeki Sugawara, Jun Hatazawa, Akifumi Suzuki, Kazuhiro Takahashi and Shuuichi Miura
J Cereb Blood Flow Metab 25: S351-S351; doi:10.1038/sj.jcbfm.9591524.0351
Assessment of lithium treatment using fMRI during stroke recovery in rats
Young R Kim, Maurits P A van Meer, Emiri Tejima, Joe B Mandeville, Teng-Yi Huang, De M Chuang, Bruse R Rosen and Eng H Lo
J Cereb Blood Flow Metab 25: S352-S352; doi:10.1038/sj.jcbfm.9591524.0352
Age dependence of 18F-fluorodopa uptake rate and dopamine turnover PET markers and implications for Parkinson's disease progression
Vesna Sossi, James E Holden, Michael Schulzer, Thomas J Ruth and A Jonathan Stoessl
J Cereb Blood Flow Metab 25: S353-S353; doi:10.1038/sj.jcbfm.9591524.0353
Multimodal navigation system with integration of PET data in the surgical treatment of intrinsic brain tumors
Toshio Sasajima, Hiroyuki Kinouchi, Masanobu Ibaraki, Eku Shimosegawa, Kazuhiro Takahashi, Tohru Ohta, Kennichi Shibata, Akira Suzuki, Jun Hatazawa, Iwao Kanno and Kazuo Mizoi
J Cereb Blood Flow Metab 25: S354-S354; doi:10.1038/sj.jcbfm.9591524.0354
Interhemispheric neural conduction velocity estimated by auditory-evoked magnetic fields decreases correlating with the degree of depressive mood in elderly subjects
Hiroshi Oe, Akihiko Kandori, Tsuyoshi Miyashita, Kuniomi Ogata, Kotaro Miyashita, Kuni Konaka, Keiji Tsukada and Hiroaki Naritomi
J Cereb Blood Flow Metab 25: S355-S355; doi:10.1038/sj.jcbfm.9591524.0355
Modelling focal brain lesions: Perfusion changes induced by rTMS over language related cortex
Alexander Thiel, Birgit Schumacher, Karl Herholz, Klaus Wienhard, Walter F Haupt and Wolf-Dieter Heiss
J Cereb Blood Flow Metab 25: S356-S356; doi:10.1038/sj.jcbfm.9591524.0356
Diagnosis of mild cognitive impairment using fractal analysis in CBF SPECT
Naohiko Oku, Kenya Murase, Kazuo Kitagawa, Yasuyuki Kimura, Katsufumi Kajimoto, Ashik Bin Anser, Makiko Tanaka, Hiroki Katoh, Masatsugu Hori and Jun Hatazawa
J Cereb Blood Flow Metab 25: S357-S357; doi:10.1038/sj.jcbfm.9591524.0357
Finger flexion contrasted to extension activates higher-order motor circuitry
M W Stenekes, J M Hoogduin, Th Mulder, J H B Geertzen, K L Leenders, J-P A Nicolai and B M de Jong
J Cereb Blood Flow Metab 25: S358-S358; doi:10.1038/sj.jcbfm.9591524.0358
Assessment of heamodynamic parameters and cerebral blood flow reactivity using in vivo bolus tracking and arterial spin labeling in mice
Greetje Vanhoutte, Marleen Verhoye and Annemie Van der Linden
J Cereb Blood Flow Metab 25: S359-S359; doi:10.1038/sj.jcbfm.9591524.0359
Task intensity related brain activation by ergometer exercise measured by FDG-PET
Sabina Khondkar, Keiichiro Yamaguchi, Shoichi Watanuki, Toshihiko Fujimoto and Masatoshi Itoh
J Cereb Blood Flow Metab 25: S360-S360; doi:10.1038/sj.jcbfm.9591524.0360
A longitudinal and totally noninvasive fMRI protocol in rats
Ralph Weber, Pedro Ramos-Cabrer, Dirk Wiedermann and Mathias Hoehn
J Cereb Blood Flow Metab 25: S361-S361; doi:10.1038/sj.jcbfm.9591524.0361
Detection of chronic hemosiderin-loaded macrophages accumulation after stroke in the rat. Indicator of late vascular degradation?
Ralph Weber, Susanne Wegener, Pedro Ramos-Cabrer, Ulla Uhlenkueken and Mathias Hoehn
J Cereb Blood Flow Metab 25: S362-S362; doi:10.1038/sj.jcbfm.9591524.0362
Possible cortico-subcortical motor circuit disruption in patients with vascular parkinsonism
Masafumi Ihara, Hidekazu Tomimoto, Koichi Ishizu, Hidefumi Yoshida, Nobukatsu Sawamoto, Kazuo Hashikawa and Hidenao Fukuyama
J Cereb Blood Flow Metab 25: S363-S363; doi:10.1038/sj.jcbfm.9591524.0363
Prefrontal cortical response to verbal-spatial two-dimensional task measured by functional NIRS
Chenjun Li, Hui Gong and Qingming Luo
J Cereb Blood Flow Metab 25: S364-S364; doi:10.1038/sj.jcbfm.9591524.0364
Quantitation of ketamine induced changes of rCBF
Hans R Herzog, Holger Holthusen, Jan-Peter Nickel and Lars Kemna
J Cereb Blood Flow Metab 25: S365-S365; doi:10.1038/sj.jcbfm.9591524.0365
Visualizing the effects of scopolamine in the rat brain using functional MRI
Diana Cash, Toby J Roberts, Matthew D Ireland, Steve C R Williams, Jacqueline A Hunter, Neil Upton and David Virley
J Cereb Blood Flow Metab 25: S366-S366; doi:10.1038/sj.jcbfm.9591524.0366
Spatiotemporal correlation of neuronal activity and cerebral blood flow of the motor cortex: Non-invasive measurement of DC-EEG and near-infrared spectroscopy in humans during a motor task
Christoph W Drenckhahn, Rainer Papsdorf, Jens Steinbrink, Hellmuth Obrig, Stefanie Leistner, Bruno M Mackert, Gabriel Curio, Arno Villringer, Ulrich Dirnagl, Matthias Kohl-Bareis and Jens P Dreier
J Cereb Blood Flow Metab 25: S367-S367; doi:10.1038/sj.jcbfm.9591524.0367
Activation of the visual cortex in infants during natural sleep using multichannel near-infrared spectroscopy
Kusaka Takashi, Isobe Kenichi, Okubo Kensuke, Yasuda Saneyuki, Kawada Kou and Itoh Susumu
J Cereb Blood Flow Metab 25: S368-S368; doi:10.1038/sj.jcbfm.9591524.0368
Dynamic relationship between changes in CBF and CBV during somatosensory stimulation: Implications for calibrated fMRI
Ikuhiro Kida and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S369-S369; doi:10.1038/sj.jcbfm.9591524.0369
Visualizing activated microglias in Wernicke-Korsakoff syndrome by [11C]PK11195 and PET
Mihoko Tsukahara, Kenji Ishii, Yuichi Kimura, Sachio Matsushita, Susumu Higuchi and Kiichi Ishiwata
J Cereb Blood Flow Metab 25: S370-S370; doi:10.1038/sj.jcbfm.9591524.0370
Coupling between evoked neural and hemodynamic responses in the somatosensory cortex of isoflurane-anesthetized rats
Kazuto Masamoto, Tae Kim, Mitsuhiro Fukuda, Ping Wang and Seong-Gi Kim
J Cereb Blood Flow Metab 25: S371-S371; doi:10.1038/sj.jcbfm.9591524.0371
Non-stationary Gaussian spatio-temporal modeling of fMRI data
Jean-Michel Pignat, Oleksiy Koval, Sviatoslav Voloshynoskiy, Vicente Ibanez and Thierry Pun
J Cereb Blood Flow Metab 25: S372-S372; doi:10.1038/sj.jcbfm.9591524.0372
Correlation of changes in cortical bold MR contrast, near-infrared spectroscopy and laser Doppler flow during brain activation and transient hypertension
Ursula I Tuor, Min Qiao, Rong Wang, David Rushforth, Tadeusz Foniok, Susan Sea, Boguslaw Tomanek and R Anthony Shaw
J Cereb Blood Flow Metab 25: S373-S373; doi:10.1038/sj.jcbfm.9591524.0373
The use of depth-resolved optical imaging to separate cortical vascular compartments during functional activation
Elizabeth M C Hillman, Anna Devor, Anders M Dale, Andrew K Dunn and David A Boas
J Cereb Blood Flow Metab 25: S374-S374; doi:10.1038/sj.jcbfm.9591524.0374
Pure anarthria due to precentral gyrus infarction: fMRI study
Takanori Oikawa, Reiko Fukatsu, Kinya Hisanaga, Masaaki Kato, Hiroshi Mochizuki and Hiroshi Saito
J Cereb Blood Flow Metab 25: S375-S375; doi:10.1038/sj.jcbfm.9591524.0375
5-HT1A receptor density and defensive personality - interaction of neurochemistry, personality and depression explored with [11C]WAY 100635 PET
Eugenii A Rabiner, Andrew D Lawrence, Zubin Bhagwagar, N Venkatesha Murthy, R Alexander Bantick, Philip J Cowen and Paul M Grasby
J Cereb Blood Flow Metab 25: S376-S376; doi:10.1038/sj.jcbfm.9591524.0376
Quantitative PET determination of pericontusional tissue viability: Correlation with diagnostic CT imaging and implications for surgical removal following traumatic brain injury
Hsiao-Ming Wu, Sung-Cheng Huang, Chin-Lung Yu, Thomas C Glenn, Paul M Vespa, David A Hovda and Marvin Bergsneider
J Cereb Blood Flow Metab 25: S377-S377; doi:10.1038/sj.jcbfm.9591524.0377
Dynamic cerebral responses to prolonged hypoglycaemia in healthy volunteers measured using [15O]-H20 PET
Joel T Dunn, Laurence J Reed, Iain A Cranston, Paul K Marsden and Stephanie A Amiel
J Cereb Blood Flow Metab 25: S378-S378; doi:10.1038/sj.jcbfm.9591524.0378
Fractal correlation structure in fMRI data of rat brain
Peter Herman, Ikuhiro Kida, Basavaraju G Sanganahalli, Fahmeed Hyder and Andras Eke
J Cereb Blood Flow Metab 25: S379-S379; doi:10.1038/sj.jcbfm.9591524.0379
Simultaneous acquisition of fMRI and EEG in the picrotoxin model of epilepsy
Michel B Mesquita, Michael J Brammer and Steven C R Williams
J Cereb Blood Flow Metab 25: S380-S380; doi:10.1038/sj.jcbfm.9591524.0380
PET-FDG study: Regional associations within the cortico-striatal circuits in OCD patients
Steven Haugbøl, Gitte M Knudsen, Stefan Kemeny, Li-Ching Lee, Steen G Hasselbalch and Elsebet S Hansen
J Cereb Blood Flow Metab 25: S381-S381; doi:10.1038/sj.jcbfm.9591524.0381
Arterial spin labeling in the presence of severe motion
Karam Sidaros, Kern Olofsson, Maria J Miranda and Olaf B Paulson
J Cereb Blood Flow Metab 25: S382-S382; doi:10.1038/sj.jcbfm.9591524.0382
Neural basis of localized and delocalized fMRI patterns
Natasja J G Maandag, Arien J Smith, Hal Blumenfeld, Robert G Shulman and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S383-S383; doi:10.1038/sj.jcbfm.9591524.0383
Does gravity affect functional cerebral blood flow response?
Elizabeth R Devine, William P Milberg and Jorge M Serrador
J Cereb Blood Flow Metab 25: S384-S384; doi:10.1038/sj.jcbfm.9591524.0384
Modelling the bold response, a numerical approach
Egill Rostrup and Olaf B Paulson
J Cereb Blood Flow Metab 25: S385-S385; doi:10.1038/sj.jcbfm.9591524.0385
Using pharmacological MRI to map the dose dependent actions of the AMPA potentiator LY451395 in the rat brain
Nicholas Jones, Michael J O'Neill, Mark Tricklebank and Steve C R Williams
J Cereb Blood Flow Metab 25: S386-S386; doi:10.1038/sj.jcbfm.9591524.0386
Functional stimulation during cerebral ischemia
Mark G Burnett, Tomokazu Shimazu, Tamas Szabados, Hiromi Muramatsu, John A Detre and Joel H Greenberg
J Cereb Blood Flow Metab 25: S387-S387; doi:10.1038/sj.jcbfm.9591524.0387
Detection of haemodynamic changes in zebra finch brain by optical and functional magnetic resonance imaging
Tiny Boumans, Clémentine Vignal, Stéphane Ramstein, Marleen Verhoye, Johan Van Audekerke, Stéphane Mottin, Nicolas Mathevon and Annemie Van der Linden
J Cereb Blood Flow Metab 25: S388-S388; doi:10.1038/sj.jcbfm.9591524.0388
No association between genotypes of the 5-HT2A receptor gene and [18F]altanserin binding as measured with PET
Steven Haugbøl, Lars H Pinborg, Steen G Hasselbalch, Vibe G Frøkjær, Lis Hasholt and Gitte M Knudsen
J Cereb Blood Flow Metab 25: S389-S389; doi:10.1038/sj.jcbfm.9591524.0389
Serotonin receptor binding in mild cognitive impairment studied by PET and [18F]-altanserin
Steen G Hasselbalch, Karine Madsen, Claus Svarer, Lars Pinborg, Jette Stokholm, Søren Holm, Olaf B Paulson, Gunhild Waldemar and Gitte M Knudsen
J Cereb Blood Flow Metab 25: S390-S390; doi:10.1038/sj.jcbfm.9591524.0390
Assessment of microglia activation in schizophrenia using [11C](R)-PK11195 and PET
Bart N M van Berckel, Ronald Boellaard, Marc A Kropholler, Esther Caspers, Wiepke Cahn, Adriaan A Lammertsma and René S Kahn
J Cereb Blood Flow Metab 25: S391-S391; doi:10.1038/sj.jcbfm.9591524.0391
In vivo multimodal (MRI, SPECT) imaging of the 6-OHDA rat model for Parkinson's disease correlated with behavior and histology
Nadja Van Camp, Koen Van Laere, Ruth Vreys, Marleen Verhoye, Erwin Lauwers, Dirk Bequé, Frederic Maes, Alfons Verbruggen, Zeger Debyzer, Luc Mortelmans, Jan Sijbers, Johan Nuyts, Veerle Baekelandt and Annemie Van der Linden
J Cereb Blood Flow Metab 25: S392-S392; doi:10.1038/sj.jcbfm.9591524.0392
Differentiation of Lewy body dementia from Parkinson's disease with [C-11]DTBZ PET
Robert A Koeppe, Sid Gilman, Larry Junck, Mary Heumann, Kris Wernette and Kirk A Frey
J Cereb Blood Flow Metab 25: S393-S393; doi:10.1038/sj.jcbfm.9591524.0393
Intracranial vascular transfer function in acute stroke patients
Yang Wu, Hongyu An, Hamid Krim, Katie Vo, Jin-Moo Lee and Weili Lin
J Cereb Blood Flow Metab 25: S394-S394; doi:10.1038/sj.jcbfm.9591524.0394
Influence of volatile induction agents on fMRI and neural activity
Basavaraju G Sanganahalli, Peter Herman and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S395-S395; doi:10.1038/sj.jcbfm.9591524.0395
A comparative F-dopa and FDG PET study of parkinsonian subjects without evidence of dopaminergic dysfunction
Vijay Dhawan, Andy Feigin, Yilong Ma, Dan Lewis, Chaorui Huang and David Eidelberg
J Cereb Blood Flow Metab 25: S396-S396; doi:10.1038/sj.jcbfm.9591524.0396
Effects of isoflurane induction on inter-animal reproducibility
Basavaraju G Sanganahalli, Peter Herman and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S397-S397; doi:10.1038/sj.jcbfm.9591524.0397
Acute insulin induced hypoglycemia: Blood flow and metabolism in humans
Richard P Kennan, Kan Takahashi, Harry Shamoon and Jullie W Pan
J Cereb Blood Flow Metab 25: S398-S398; doi:10.1038/sj.jcbfm.9591524.0398
Assessment of acute metabolic stress following traumatic brain injury with 1 H magnetic resonance spectroscopic imaging in human subjects
Paul M Vespa, David L McArthur, Maria Etchepare and Jeffry R Alger
J Cereb Blood Flow Metab 25: S399-S399; doi:10.1038/sj.jcbfm.9591524.0399
Temporal evolution of cerebral metabolic rate of oxygen utilization using MRI in a middle cerebral artery occlusion stroke
Hongyu An, Liansheng Chang, Yang Wu, Yasheng Chen and Weili Lin
J Cereb Blood Flow Metab 25: S400-S400; doi:10.1038/sj.jcbfm.9591524.0400
Volatile induction agents affect adaptation in -chloralose anesthetized rat
Basavaraju G Sanganahalli, Peter Herman and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S401-S401; doi:10.1038/sj.jcbfm.9591524.0401
Transient increases in blood pressure affect sensory-motor activation following stroke using functional MR imaging in the rat
Rong Wang, Zhonghang Zhao, David Rushforth, Tadeusz Foniok, Jaclyn I Wamsteeker, Alastair Buchan, Boguslaw Tomanek and Ursula I Tuor
J Cereb Blood Flow Metab 25: S402-S402; doi:10.1038/sj.jcbfm.9591524.0402
Evaluation of serotonin 1A receptor binding in diabetes and depression
Julie C Price, David E Kelley, Sigrid A Hagg, Christopher M Ryan, Scott K Ziolko, Carolyn C Meltzer, Dana Tudorascu, Lisa A Weissfeld, Sati Mazumdar, Chester A Mathis and Charles F Reynolds
J Cereb Blood Flow Metab 25: S403-S403; doi:10.1038/sj.jcbfm.9591524.0403
Decreasing systemic blood pressure impairs cerebral vascular reserves in patients with steno-occlusive cerebral vascular diseases: A repeated I-123 split dose spect study
Yasuyuki Kimura, Naohiko Oku, Katsufumi Kajimoto, Hiroki Kato, Makiko Tanaka, Ashik M D Ansar Bin, Masakazu Kanai, Kazuo Kitagawa and Jun Hatazawa
J Cereb Blood Flow Metab 25: S404-S404; doi:10.1038/sj.jcbfm.9591524.0404
Comparison of bolus injection and continuous infusion arterial inputs in Gd-DTPA contrast-enhanced MRI
Tavarekere N Nagaraja, Vijaya Nagesh, James R Ewing, Polly A Whitton, Joseph D Fenstermacher and Robert A Knight
J Cereb Blood Flow Metab 25: S405-S405; doi:10.1038/sj.jcbfm.9591524.0405
Higher rate of cortical infarcts shown in acute stroke patients using high resolution diffusion weighted imaging
Karima Benameur, Julie Bykowski, Marie Luby, Naomi Lewin, Steven Warach and Lawrence Latour
J Cereb Blood Flow Metab 25: S406-S406; doi:10.1038/sj.jcbfm.9591524.0406
Abnormal covariance metabolic topography in patients with progressive supranuclear palsy: A FDG PET study
Yilong Ma, Shivani Rachakonda, Thomas Eckert, Andy Feigin, Vijay Dhawan and David Eidelberg
J Cereb Blood Flow Metab 25: S407-S407; doi:10.1038/sj.jcbfm.9591524.0407
Study of tissue atrophy involvement in semantic dementia using elastic mapping
Alex Leow, Sung-Cheng Huang, James Becker and Paul Thompson
J Cereb Blood Flow Metab 25: S408-S408; doi:10.1038/sj.jcbfm.9591524.0408
High resolution measurements of neuronal activity, cerebral blood flow, and fMRI during spike-wave seizures in WAG/Rij rats
Hal Blumenfeld, Hrachya Nersesyan, Manjula Khubchandani, Ulrich Schridde, Rachel Berman, Douglas Rothman and Fahmeed Hyder
J Cereb Blood Flow Metab 25: S409-S409; doi:10.1038/sj.jcbfm.9591524.0409
Mapping the functional effects of the AMPA receptor potentiators LY450108 and LY451395 with 14C 2-deoxyglucose autoradiography
Jill H Fowler, Michael J O'Neill, David Bleakman and James McCulloch
J Cereb Blood Flow Metab 25: S410-S410; doi:10.1038/sj.jcbfm.9591524.0410
Estimation of the temporal features of CMRO2 changes from CBF and bold fMRI data
Alberto L Vazquez, Vikas Gulani, Gregory Lee, Hernandez-Garcia Luis and Douglas C Noll
J Cereb Blood Flow Metab 25: S411-S411; doi:10.1038/sj.jcbfm.9591524.0411
Diffuse optical measurement of cerebral metabolic rate of oxygen in adult brain
Turgut Durduran, Guoqiang Yu, Mark G Burnett, Chao Zhou, Jiongjiong Wang, John A Detre, Arjun G Yodh and Joel H Greenberg
J Cereb Blood Flow Metab 25: S412-S412; doi:10.1038/sj.jcbfm.9591524.0412
Development of diffuse correlation techniques for non-invasive measurement of cerebral blood flow and oxygen metabolism in rats
Turgut Durduran, Guoqiang Yu, Chao Zhou, Daisuke Furuya, Joseph P Culver, Arjun G Yodh and Joel H Greenberg
J Cereb Blood Flow Metab 25: S413-S413; doi:10.1038/sj.jcbfm.9591524.0413
Neural activation in human brain detected with hyperpolarized 129XE and MRI
Yasushi Kondoh, Kazuhiro Nakamura, Jeff Kershaw, Atsushi Wakai, Naoyuki Takei, Tetsuji Tsukamoto and Iwao Kanno
J Cereb Blood Flow Metab 25: S414-S414; doi:10.1038/sj.jcbfm.9591524.0414
Follow-up study of amyloid deposition and glucose metabolism in patients with Alzheimer's disease
Anton Forsberg, Henry Engler, Emma Larsson, Gunnar Blomquist, Anders Wall, Bengt Långström and Agneta Nordberg
J Cereb Blood Flow Metab 25: S415-S415; doi:10.1038/sj.jcbfm.9591524.0415
Sedative profiles of antihistamine drugs evaluated by subjective sleepiness, cognitive tests, and PET for measurement of cerebral histamine H1 receptor occupancy
Manabu Tashiro, Yumiko Sakurada, Hideki Mochizuki, Etsuo Horikawa, Motohisa Kato, Masatoshi Itoh and Kazuhiko Yanai
J Cereb Blood Flow Metab 25: S416-S416; doi:10.1038/sj.jcbfm.9591524.0416
Region-specific, longitudinal assessment of functional recovery of reperfused brain following transient focal ischemia in mice using bicuculline-induced brain activation
Téa Kekelidze, Annett Spudich, Martin Rausch, Diana Kindler, Claudio Bassetti, Markus Rudin, Ernst Martin and Dirk Hermann
J Cereb Blood Flow Metab 25: S417-S417; doi:10.1038/sj.jcbfm.9591524.0417
Improving mean transit time calculations with better estimates of arterial delay
George C Newman, Frank Hospod and Evan Delucia-Deranja
J Cereb Blood Flow Metab 25: S418-S418; doi:10.1038/sj.jcbfm.9591524.0418
Preparation, characterization and application of an albumin-linked, gadolinium-based magnetic resonance contrast agent
Tavarekere N Nagaraja, Richard L Croxen, Swayamprava Panda, Jamie Churchman, Polly A Whitton, Stephen L Brown, Joseph D Fenstermacher and James R Ewing
J Cereb Blood Flow Metab 25: S419-S419; doi:10.1038/sj.jcbfm.9591524.0419
Muscarinic cholinergic2 receptor binding in bipolar disorder: Relation to saliency of affective-words
Dara M Cannon, Allison C Nugent, Kristine Erickson, Rich E Carson, William C Eckelman, Dale O Kiesewetter, Earle E Bain, Shilpa K Gandhi, Gerardo Solorio, Dennis Charney and Wayne C Drevets
J Cereb Blood Flow Metab 25: S420-S420; doi:10.1038/sj.jcbfm.9591524.0420
Absolute versus relative 'deactivation': A comparison of seven cognitive tasks using quantitative XE-133 SPECT
Georg Deutsch, Beverly Corbitt, Omur Sen, Hong-Gang Liu and Janis O'Malley
J Cereb Blood Flow Metab 25: S421-S421; doi:10.1038/sj.jcbfm.9591524.0421
Neuroinflammation
Oral session
Poster Session
Neurogenesis in organotypic hippocampal slice cultures inhibited by inflammation early after oxygen-glucose deprivation is restored at later time point
Olga Chechneva, Klaus M Dinkel and Klaus G Reymann
J Cereb Blood Flow Metab 25: S97-S97; doi:10.1038/sj.jcbfm.9591524.0097
Neuroprotective role of Fc gamma receptor in ischemia-reperfusion injury using Fc gamma receptor knockout mice
Takao Urabe, Miki Komine-Kobayashi, Ning Zhang and Yoshikuni Mizuno
J Cereb Blood Flow Metab 25: S98-S98; doi:10.1038/sj.jcbfm.9591524.0098
SOD1 overexpression reduces MCP-1 and MIP-1 expression after transient focal cerebral ischemia
Tatsuro Nishi, Carolina M Maier, Hidenori Endo, Hiroshi Kamada and Pak H Chan
J Cereb Blood Flow Metab 25: S99-S99; doi:10.1038/sj.jcbfm.9591524.0099
Microglia potentiate injury to the blood brain barrier: reverseal by minocycline
Xian N Tang, Yanli Qiao, Lijun Xu, Rona Giffard and Midori A Yenari
J Cereb Blood Flow Metab 25: S100-S100; doi:10.1038/sj.jcbfm.9591524.0100
Osteopontin mediates neuroprotection via inhibition of inducible nitric oxide synthase
Sebastian Jander, Michael Schroeter and David T Denhardt
J Cereb Blood Flow Metab 25: S101-S101; doi:10.1038/sj.jcbfm.9591524.0101
Temporal progression of seizures-induced amygdaloallocortical microvascular inflammation leading to edema and multifocal microhemorrhagic stroke in the rat
Sima Mraovitch, Angélique Régnier, Yolande Calando and Eric Vicaut
J Cereb Blood Flow Metab 25: S102-S102; doi:10.1038/sj.jcbfm.9591524.0102
Peripheral administration of interleukin-1 exacerbates ischaemic brain damage after transient focal ischaemia in mice
Barry W McColl, Nancy J Rothwell and Stuart M Allan
J Cereb Blood Flow Metab 25: S103-S103; doi:10.1038/sj.jcbfm.9591524.0103
Expression of cyclophilin C-associated protein and cyclophilin C mRNAs in focal cerebral ischemia
Tatsuya Shimizu, Hideaki Imai, Koji Seki, Shinichiro Tomizawa, Mitsunobu Nakamura, Fumiaki Honda, Nobutaka Kawahara and Nobuhito Saito
J Cereb Blood Flow Metab 25: S104-S104; doi:10.1038/sj.jcbfm.9591524.0104
Innate immune signal transduction mediated hyperphosphorylation of tau and inflammatory changes in human SH-SY5Y neuroblastoma cells
Nurun N Begum, Toshihisa Tanaka, Golam Sadik, Md. Ashik B Ansar, Takashi Kudo and Masatoshi Takeda
J Cereb Blood Flow Metab 25: S105-S105; doi:10.1038/sj.jcbfm.9591524.0105
The TNFalpha-transgenic rat: A new model of cytokine-mediated ischemic brain injury
L Creed Pettigrew, Mary L Holtz, Mark S Kindy, Thomas C Foster, David S Grass and Susan D Craddock
J Cereb Blood Flow Metab 25: S106-S106; doi:10.1038/sj.jcbfm.9591524.0106
The hepatic chemokine response to spinal cord injury - a new target for therapeutic intervention
Sandra J Campbell and Daniel C Anthony
J Cereb Blood Flow Metab 25: S107-S107; doi:10.1038/sj.jcbfm.9591524.0107
Systemic administration of lipopolysaccharide during transient focal cerebral ischemia leads to chronic CNS inflammation
Kyra J Becker, Darin L Kindrick, Mark P Lester and Connor P Shea
J Cereb Blood Flow Metab 25: S108-S108; doi:10.1038/sj.jcbfm.9591524.0108
Sex differences in posttraumatic inflammatory cytokines in the rat brain
Sylvia Guerrero, Karell Curbelo, Ofelia Furones-Alonso and Helen M Bramlett
J Cereb Blood Flow Metab 25: S109-S109; doi:10.1038/sj.jcbfm.9591524.0109
Effects of intrauterine inflammation on developing mouse brain
Xiaoyang Wang, Carina Mallard, Bo Jacobsson and Henrik Hagberg
J Cereb Blood Flow Metab 25: S110-S110; doi:10.1038/sj.jcbfm.9591524.0110
Gonadal hormones modulate LPS-induced inflammatory markers in rat cerebral blood vessels
Rayna Gonzales, Ali Razmara, Lorraine Sunday, Diana Krause and Sue Duckles
J Cereb Blood Flow Metab 25: S111-S111; doi:10.1038/sj.jcbfm.9591524.0111
Interleukin-6 triggers human cerebral smooth muscle cell proliferation
Jinghua S Yao, Zheng Xue, William L Young and Guo-Yuan Yang
J Cereb Blood Flow Metab 25: S112-S112; doi:10.1038/sj.jcbfm.9591524.0112
Neuro-inflammation
Oral session
Oral session
Adhesion of leukocytes to cerebral endothelium is sufficient to trigger delayed neuronal cell death following focal cerebral ischemia
Hiroharu Kataoka, Seong-Woong Kim and Nikolaus Plesnila
J Cereb Blood Flow Metab 25: S91-S91; doi:10.1038/sj.jcbfm.9591524.0091
Contribution of vascular adhesion protein-1 (VAP-1) to post-ischemic cerebral venular leukocyte adhesion and infiltration in diabetic, ovariectomized (OVX) and estrogen-treated female rats
Hao-Liang Xu, Matthew D Linnik, Luisa Salter-Cid and Dale A Pelligrino
J Cereb Blood Flow Metab 25: S92-S92; doi:10.1038/sj.jcbfm.9591524.0092
Soluble epoxide hydrolase gene deletion reduces inflammation after stroke
Ines P Koerner, Wenri Zhang, Patricia D Hurn, Dennis Koop and Nabil J Alkayed
J Cereb Blood Flow Metab 25: S93-S93; doi:10.1038/sj.jcbfm.9591524.0093
PPAR- agonist rosiglitazone decreases focal cerebral ischemia-induced inflammation and brain damage in adult mice
Kudret Tureyen, Ramya Sundaresan, Kellie Bowen and Raghu Vemuganti
J Cereb Blood Flow Metab 25: S94-S94; doi:10.1038/sj.jcbfm.9591524.0094
PARP-1 promotes microglial activation, proliferation, and MMP-9-mediated neuron death
Tiina M Kauppinen and Raymond A Swanson
J Cereb Blood Flow Metab 25: S95-S95; doi:10.1038/sj.jcbfm.9591524.0095
HSP70 protects against experimental stroke through the inhibition of postischemic inflammatory reaction
Zhen Zheng, Yanli Qiao, Nina Dunphy, Joyce Ma, Jong Eun Lee and M A Yenari
J Cereb Blood Flow Metab 25: S96-S96; doi:10.1038/sj.jcbfm.9591524.0096
Neurointensive Care, Monitoring, Trauma
Oral session
Variability of SF-36 scores within gose categories
Joanne G Outtrim, Doris A Chatfield, Christine Conway-Smith, Edna Shephard, Laura Moore, Peter J Hutchinson, John D Pickard and David K Menon
J Cereb Blood Flow Metab 25: S560-S560; doi:10.1038/sj.jcbfm.9591524.0560
The relationship between brain tissue oxygen partial pressure thresholds and microdialysis markers of ischaemia in traumatic brain injury
Jurgens Nortje, Peter J Hutchinson, David A Zygun, Pippa G Al-Rawi, Mark T O'Connell, David K Menon and Arun K Gupta
J Cereb Blood Flow Metab 25: S561-S561; doi:10.1038/sj.jcbfm.9591524.0561
Can cerebral autoregulation be assessed without measuring cerebral blood flow?
Marek Czosnyka, Ajay Kumar, Luzius Steiner, Eric A Schmidt and John D Pickard
J Cereb Blood Flow Metab 25: S562-S562; doi:10.1038/sj.jcbfm.9591524.0562
Asymmetry of cerebral circulation in injured brain
Marek Czosnyka, Piotr Smielewski, Ajay Kumar, Eric A Schmidt, Magdalena Hiler, Basil F Matta and John D Pickard
J Cereb Blood Flow Metab 25: S563-S563; doi:10.1038/sj.jcbfm.9591524.0563
Increased pentose phosphate cycle flux following severe traumatic brain injury: a 13C-labeling study
Joshua R Dusick, Thomas C Glenn, Yung C Lee, W N Paul Lee, Paul M Vespa, Sara Bassilian, Soyoun J Lee, Stefan M Lee and Neil A Martin
J Cereb Blood Flow Metab 25: S564-S564; doi:10.1038/sj.jcbfm.9591524.0564
The application of rapid-sampling, on-line microdialysis to intraoperative brain monitoring during aneurysm surgery
Robin Bhatia, Parastoo Hashemi, Emma Perpinan-Corcoles, Mark C Parkin, Sarah E Hopwod, Martyn G Boutelle and Anthony J Strong
J Cereb Blood Flow Metab 25: S565-S565; doi:10.1038/sj.jcbfm.9591524.0565
The lactate:pyruvate ratio affects hyperemia in humans following traumatic brain injury
Daniel Hirt, Thomas C Glenn, Paul M Vespa, Jane S Y Lee and Neil A Martin
J Cereb Blood Flow Metab 25: S566-S566; doi:10.1038/sj.jcbfm.9591524.0566
Cerebral lactate extraction fraction and outcome following human traumatic brain injury
Thomas C Glenn, W John Boscardin, Paul M Vespa, David A Hovda, Daniel F Kelly and Neil A Martin
J Cereb Blood Flow Metab 25: S567-S567; doi:10.1038/sj.jcbfm.9591524.0567
Detecting brainstem injury with acute MRI following severe head trauma
Richard J Mannion, David Menon, Justin Cross, Peter Bradbury, Jonathan Coles, Dot Chatfield, John D Pickard and Peter J A Hutchinson
J Cereb Blood Flow Metab 25: S568-S568; doi:10.1038/sj.jcbfm.9591524.0568
'ICM+': Versatile software for analysis of cerebrovascular dynamics in clinical practice
Peter Smielewski, Marek Czosnyka, Philip Lewis and John D Pickard
J Cereb Blood Flow Metab 25: S569-S569; doi:10.1038/sj.jcbfm.9591524.0569
Effects of subdural hemorrhage, mass lesion and controlled cortical impact on multi-parametric neuromonitoring in pigs
Beat Alessandri, Ralph Timaru-Kast, Anke Meissner, Oliver Kempski and Axel Heimann
J Cereb Blood Flow Metab 25: S570-S570; doi:10.1038/sj.jcbfm.9591524.0570
Investigation of the cerebral haemoglobin and cytochrome signals using near infrared spectroscopy during head up tilt in patients with orthostatic hypotension
Martin Tisdall, Ilias Tachtsidis, Katharine Bleasdale-Barr, Chris J Mathias, Dave T Delpy, Clare E Elwell and Martin Smith
J Cereb Blood Flow Metab 25: S571-S571; doi:10.1038/sj.jcbfm.9591524.0571
Carbon dioxide provides neuroprotection in fluid percussion injured rats
Michael L Rolli, Eleanor Lee, Anthony J Williams, Geoffrey S F Ling and Frank C Tortella
J Cereb Blood Flow Metab 25: S572-S572; doi:10.1038/sj.jcbfm.9591524.0572
Can we assess cerebrovascular autoregulation after head injury using brain tissue oxygen pressure reactivity?
Matthias Jaeger, Martin Soehle, Martin U Schuhmann and Jürgen Meixensberger
J Cereb Blood Flow Metab 25: S573-S573; doi:10.1038/sj.jcbfm.9591524.0573
Radiographic validity of transcranial Doppler cerebral blood flow velocity measurement
Michael J Souter, Gavin W Britz, Michael S Kincaid, Basavaraj Ghodke and Arthur M Lam
J Cereb Blood Flow Metab 25: S574-S574; doi:10.1038/sj.jcbfm.9591524.0574
Failure of pentobarbital to reduce cerebral oxygen consumption in rats after non-haemorrhagic closed head injury
Geofrey De Visscher, Servan Rooker, Helga Blockx, Phillippe Jorens, Jan Verlooy, Marcel Borgers, Robert S Reneman, Koen van Rossem and Willem Flameng
J Cereb Blood Flow Metab 25: S575-S575; doi:10.1038/sj.jcbfm.9591524.0575
Neurotransmitters and Receptors
Oral session
Effects of adrenomedullin on nitric-oxide production during forebrain ischemia and reperfusion in mice
Daisuke Furuya, Nobuo Araki, Takeshi Okubo, Yoshio Asano, Masahiko Sawada, Tomokazu Shimazu, Harumitsu Nagoya, Masamizu Yamazato, Yasuo Ito, Yuji Kato, Mikiko Ninomiya and Kunio Shimazu
J Cereb Blood Flow Metab 25: S576-S576; doi:10.1038/sj.jcbfm.9591524.0576
Simultaneous measurement of dopamine transporters and D2/D3 receptors in drug naïve schizophrenia
Yuan-Hwa Chou, Tung-Ping Su, Wen-Sheng Huang and Ying-Kai Fu
J Cereb Blood Flow Metab 25: S577-S577; doi:10.1038/sj.jcbfm.9591524.0577
Desmoteplase (DSPA) does not interact with or cleave the NMDA receptor NR1 subunit: Possible molecular basis for improved tolerability in treatment of acute ischemic stroke
José Lopez Atalaya, Karim Benchenane, Hervé Castel, Carine Ali, Karl-Uwe Petersen and Denis Vivien
J Cereb Blood Flow Metab 25: S578-S578; doi:10.1038/sj.jcbfm.9591524.0578
Physiological and pathological implications of the tPA/NR1 interaction : An immunization-based investigation
Hervé Castel, Karim Benchenane, Monica Fernandez-Monreal, José Lopez-Atalaya, Rose-Marie Bluthé, Michel Boulouard, François Dauphin, Eric T MacKenzie, Robert Dantzer, Omar Touzani, Carine Ali and Denis Vivien
J Cereb Blood Flow Metab 25: S579-S579; doi:10.1038/sj.jcbfm.9591524.0579
Cerebral nicotinic acetylcholine receptors in patients with Alzheimer's disease or vascular dementia - evaluation with 2-[18F]F-A85380 and positron emission tomography (PET)
Kai Kendziorra, Philipp Meyer, Henryk Barthel, Georg Becker, Dietlind Sorger, Andreas Schildan, Swen Hesse, Marianne Patt, Anita Seese, Kristina Richter, Eva Hammerstein, Claus Zimmer, Hermann Josef Gertz and Osama Sabri
J Cereb Blood Flow Metab 25: S580-S580; doi:10.1038/sj.jcbfm.9591524.0580
Direct cerebrovascular effects of CB1 receptor activation by the synthetic endocannabinoid HU-210 in vivo
Marion A Simpson, J Leanne Leith, Linda Ferrington and Paul A T Kelly
J Cereb Blood Flow Metab 25: S581-S581; doi:10.1038/sj.jcbfm.9591524.0581
Local cerebral metabolic response to 8-OH-DPAT in Dark Agouti rats is altered by prior exposure to 3, 4, -methylenedioxymethamphetamine (MDMA)
Linda Ferrington, J Lianne Leith, Douglas E McBean, Henry J Olverman and Paul A T Kelly
J Cereb Blood Flow Metab 25: S582-S582; doi:10.1038/sj.jcbfm.9591524.0582
Serotonin 2A receptor binding in healthy twins genetically predisposed to major depression in comparison with undisposed controls
Vibe G Frokjaer, Maj V Christensen, Kirstine A Bojsen-Moller, Erik L Mortensen, William Baare, Claus Svarer, Jakob Madsen, Lars V Kessing and Gitte M Knudsen
J Cereb Blood Flow Metab 25: S583-S583; doi:10.1038/sj.jcbfm.9591524.0583
Nicotinic acetylcholine receptors in patients with Parkinson's disease and Alzheimer's disease: Specific binding of 2-[18F]F-A-85380 in the cerebral white matter as demonstrated by PET and comparison with diffusion tensor MRI (DTI)
Philipp Meyer, Donald Lobsien, Kai Kendziorra, Henryk Barthel, Swen Hesse, Georg Becker, Andreas Schildan, Marianne Patt, Dietlind Sorger, Anita Seese, Annette Foerschler, Florian Then Bergh, Peter Brust, Jörg Steinbach, Hermann-Josef Gertz, Johannes Schwarz, Claus Zimmer and Osama Sabri
J Cereb Blood Flow Metab 25: S584-S584; doi:10.1038/sj.jcbfm.9591524.0584
Neurosteroids sensitize female mice to stress
Althea S Hayden, Veronique Devignot, John P Adelman, James Maylie and Paco S Herson
J Cereb Blood Flow Metab 25: S585-S585; doi:10.1038/sj.jcbfm.9591524.0585
Nicotinic acetylcholine receptors in the patients with Parkinson's disease: 5IA-SPECT
Kazuo Hashikawa, Hidefumi Yoshida, Nobukatsu Sawamoto, Shigetoshi Takaya, Chihiro Namiki, Hiroko Nishi, Tomohiko Asada, Kenichi Oishi, Kenji Aso, Kazumi Iseki, Hidekazu Kawashima, Koichi Ishizu, Hideo Saji and Hidenao Fukuyama
J Cereb Blood Flow Metab 25: S586-S586; doi:10.1038/sj.jcbfm.9591524.0586
The influence of prolonged hypokinesia on the levels of GABA, glutamate and glycine in white rat brain cortex
Vilen P Hakobyan, Oleg P Sotckiy, Lusine G Zhamharyan, Varduhi H Karapetyan and Irena Z Loryan
J Cereb Blood Flow Metab 25: S587-S587; doi:10.1038/sj.jcbfm.9591524.0587
PET Methods for Alzheimer's Disease
Oral session
Oral session
In vivo imaging of beta-amyloid load in transgenic rodents with [F-18]FDDNP microPET
Vladimir Kepe, Gregory M Cole, Jie Liu, Dorothy G Flood, Stephen P Trusko, Nagichettiar Satyamurthy, Sung-Chen Huang, Gary W Small, Andrej Petric, Michael E Phelps and Jorge R Barrio
J Cereb Blood Flow Metab 25: S588-S588; doi:10.1038/sj.jcbfm.9591524.0588
Simplified quantification of PIB amyloid imaging PET studies
Brian J Lopresti, William E Klunk, Chester A Mathis, Jessica A Hoge, Scott K Ziolko, Xueling Lu, Carolyn C Meltzer, Steven T DeKosky and Julie C Price
J Cereb Blood Flow Metab 25: S589-S589; doi:10.1038/sj.jcbfm.9591524.0589
Parametric imaging of [11C]PIB studies using spectral analysis
Rainer Hinz, Gunnar Blomquist, Paul Edison and David J Brooks
J Cereb Blood Flow Metab 25: S590-S590; doi:10.1038/sj.jcbfm.9591524.0590
Regeneration and Plasticity
Oral session
Oral session
Physical activity promotes angio- and vasculogenesis in the post-ischemic brain
Karen Gertz, Josef Priller, Golo Kronenberg, Helmut Schröck, Ulrich Laufs and Matthias Endres
J Cereb Blood Flow Metab 25: S209-S209; doi:10.1038/sj.jcbfm.9591524.0209
Enriched environment and learning enhances neurogenesis and peri-infarct neuronal density after cerebral focal ischemia
Yasuhiko Matsumori, Shwuhuey M Hong, Yang Fan, Zhengyan Liu, Philip R Weinstein, Chung Y Hsu and Jialing Liu
J Cereb Blood Flow Metab 25: S210-S210; doi:10.1038/sj.jcbfm.9591524.0210
Transgenic VEGF induces post-ischemic neuroprotection, but facilitates hemodynamic steal phenomena
Hugo H Marti, Yaoming Wang, Ertugrul Kilic, Ülkan Kilic, Claudio L Bassetti and Dirk M Hermann
J Cereb Blood Flow Metab 25: S211-S211; doi:10.1038/sj.jcbfm.9591524.0211
Neurotransmitter synthesis in newborn neurons in adult rat cerebral cortex after photothrombotic ring stroke with spontaneous reperfusion
Chao Gu, Per Wester, Wei Jiang and Weigang Gu
J Cereb Blood Flow Metab 25: S212-S212; doi:10.1038/sj.jcbfm.9591524.0212
Transformation of diffuse beta-amyloid precursor protein and beta-amyloid deposits to plaques in the thalamus following transient occlusion of the middle cerebral artery in rats
Thomas van Groen, Kirsi Puurunen, Hanna-Mari Mäki, Juhani Sivenius and Jukka Jolkkonen
J Cereb Blood Flow Metab 25: S213-S213; doi:10.1038/sj.jcbfm.9591524.0213
Post-stroke neurogenesis and the neurovascular niche: Newly born neuroblasts localize to peri-infarct cortex in close association with the vascular endothelium
S Thomas Carmichael, John Ohab and Jimmy Nguyen
J Cereb Blood Flow Metab 25: S214-S214; doi:10.1038/sj.jcbfm.9591524.0214
Oral session
Poster Session
Premature cellular proliferation following cortical infarct in aged rats
Aurel Popa-Wagner, Irina Badan, Ivona Dinca, Yalikun Suofu, Raluca Vintilescu, Lary Walker and Christoff Keesler
J Cereb Blood Flow Metab 25: S215-S215; doi:10.1038/sj.jcbfm.9591524.0215
Post-ischemic gene therapy using the heparin-binding epidermal growth factor-like growth factor (HB-EGF) gene promotes functional recovery after focal cerebral ischemia in rats
Shiro Sugiura, Kazuo Kitagawa, Kenichi Todo, Emi O Matsuoka, Tsutomu Sasaki, Yoshiki Yagita, Takuma Mabuchi, Kohji Matsushita and Masatsugu Hori
J Cereb Blood Flow Metab 25: S216-S216; doi:10.1038/sj.jcbfm.9591524.0216
Expression of neurocan after transient middle cerebral artery occlusion in adult rat brain
Kentaro Deguchi, Mikiro Takaishi, Takeshi Hayashi, Atsuhiko Oohira, Shoko Nagotani, Guang Jin, HanZhe Zhang, XiQuan Wang, Yoshihide Sehara, Isao Nagano, Mikio Shoji, Masahiro Miyazaki, Nam-ho Huh and Koji Abe
J Cereb Blood Flow Metab 25: S217-S217; doi:10.1038/sj.jcbfm.9591524.0217
Vascular and haemodynamic response following chronic hypoperfusion in the developing and mature rat
Mankin Choy, Mark F Lythgoe, Vijeya Ganesan, David L Thomas, John S Thornton, Ted Proctor, Louise van der Weerd and David G Gadian
J Cereb Blood Flow Metab 25: S218-S218; doi:10.1038/sj.jcbfm.9591524.0218
Cerebral ischemia disrupts the expression of regulators of synaptic cell adhesion in synaptosomes
Willard Costain, Arsalan Haqqani, Ingrid Rasquinha, Edward Preston, Jaqueline Webster and Danica Stanimirovic
J Cereb Blood Flow Metab 25: S219-S219; doi:10.1038/sj.jcbfm.9591524.0219
Effect of cilostazol on neuronal regeneration following permanent middle cerebral artery occlusion in mice
Hiroyuki Nishimura, Toshio Takaoka, Takayuki Nakagomi, Hisao Tachibana, Hiroo Yoshikawa, Mari Fukunaga, Tatsuya Yamashita, Makoto Ishikawa, Akihiro Taguchi and Tomohiro Matsuyama
J Cereb Blood Flow Metab 25: S220-S220; doi:10.1038/sj.jcbfm.9591524.0220
Estrogen treatment post experimental stroke does not influence recovery of function
Tracy D Farr, Hilary V O Carswell, Lindsay Gallagher, Barrie Condon, Andrew J Fagan, Jim Mullin and I Mhairi Macrae
J Cereb Blood Flow Metab 25: S221-S221; doi:10.1038/sj.jcbfm.9591524.0221
Ischemic preconditioning promotes neurogenesis and angiogenesis after focal cerebral ischemia
Seung-Hoon Lee, Young-Ju Kim, Kyung-Mi Lee, Manho Kim and Byung-Woo Yoon
J Cereb Blood Flow Metab 25: S222-S222; doi:10.1038/sj.jcbfm.9591524.0222
Functional relevance of the Wnt signaling pathway in adult neural stem cells
Martin H Maurer, Robert E Feldmann, Fatemeh Sabouri, Heinrich F Bürgers, Armin Schneider and Wolfgang Kuschinsky
J Cereb Blood Flow Metab 25: S223-S223; doi:10.1038/sj.jcbfm.9591524.0223
Role of PlGF in hypoxia-induced brain angiogenesis
Moises Freitas-Andrade, Danica Stanimirovic and Maria Moreno
J Cereb Blood Flow Metab 25: S224-S224; doi:10.1038/sj.jcbfm.9591524.0224
Hypothermia following cerebral ischemia provides neuroprotection but is not beneficial toward neurogenesis
Zonghang Zhao, Jaspreet Kaur, Ping Sun, Lisa Hoyte, Rose Geransar and Alastair Buchan
J Cereb Blood Flow Metab 25: S225-S225; doi:10.1038/sj.jcbfm.9591524.0225
Neural stem cells division, migration, and differentiation in neonatal rat brain after ischemic/hypoxic injury
Masanori Iwai, Tomoaki Ikeda, Takeshi Hayashi, Guang Jin, Kentaro Deguchi, Shoko Nagotani, Hanzhe Zhang, Yoshihide Sehara, Isao Nagano, Mikio Shoji, Tsuyomu Ikenoue and Koji Abe
J Cereb Blood Flow Metab 25: S226-S226; doi:10.1038/sj.jcbfm.9591524.0226
Quantification of cerebral hemoglobin as a function of oxygenation using near-infrared time-resolved spectroscopy in a piglet model
Takashi Kusaka, Sonoko Ijichi, Kenich Isobe and Susumu Itoh
J Cereb Blood Flow Metab 25: S227-S227; doi:10.1038/sj.jcbfm.9591524.0227
Developmental changes of optical properties in infants determined by near-infrared time-resolved spectroscopy
Sonoko Ijichi, Takashi Kusaka, Kenichi Isobe, Kensuke Okubo, Saneyuki Yasuda, Kou Kawada and Susumu Itoh
J Cereb Blood Flow Metab 25: S228-S228; doi:10.1038/sj.jcbfm.9591524.0228
Administration of hematopoietic cytokines provides a favorable microenvironment for neurogenesis after stroke
Yuko Morita, Shunya Takizawa, Tsuyoshi Uesugi, Hiroshi Kawaguchi, Saori Kohara, Yoshiko Shinozaki, Sigeharu Takagi and Yukito Shinohara
J Cereb Blood Flow Metab 25: S229-S229; doi:10.1038/sj.jcbfm.9591524.0229
Neurogenesis and differentiation after domic acid induced nerodegeneration in adut rat hippocampus
Kengo Kato, Tatsushi Kamiya, Kuniko Shimazaki, Hidenori Yokota, Keiji Oguro, Takahiro Miyawaki, Cikako Nito, Simon Amemiya, Yasuhiro Nishiyama, Satoshi Suda, Toshiki Inaba, Masayuki Ueda and Yasuo Katayama
J Cereb Blood Flow Metab 25: S230-S230; doi:10.1038/sj.jcbfm.9591524.0230
Up-regulation of low-density lipoprotein receptor expression after transient MCA occlusion in rats
Hiroshi Kamada, Takeshi Hayashi, Koji Abe and Pak H Chan
J Cereb Blood Flow Metab 25: S231-S231; doi:10.1038/sj.jcbfm.9591524.0231
Comparison of the regenerative capacity of the cerebral cortex in neonatal mice following traumatic or ischemic injury
Richard H Dyck, Kimberley A Maxwell, Nimet A Maherali and Jens R Coorssen
J Cereb Blood Flow Metab 25: S232-S232; doi:10.1038/sj.jcbfm.9591524.0232
Functional recovery and increased PSA-NCAM expression following delayed administration of an anti-MAG antibody post stroke in the rat
Robert I Grundy, Sarah Collier, Colin A Cambell, Kevin L Wilson, Jenny C Roberts, Mary Vinson, John B Davis and Elaine A Irving
J Cereb Blood Flow Metab 25: S233-S233; doi:10.1038/sj.jcbfm.9591524.0233
Impact of chronic prenatal intermittent hypoxia on neuronal migration
Jennifer Zechel, Michael Buczek, Jorge L Gamboa, Michelle Puchowitz and W David Lust
J Cereb Blood Flow Metab 25: S234-S234; doi:10.1038/sj.jcbfm.9591524.0234
The hematopoietic factor G-CSF is a neuronal ligand that drives neurogenesis
Armin Schneider, Carola Krüger, Tobias Steigleder, Daniela Weber, Claudia Pitzer, Martin Maurer, Nikolaus Gassler, Rainer Kollmar, Stefan Schwab, Hans-Georg Kuhn and Wolf-R Schäbitz
J Cereb Blood Flow Metab 25: S235-S235; doi:10.1038/sj.jcbfm.9591524.0235
Inhibition of cyclooxygenase-2 reduces proliferation of endogenous neural progenitors and ameliorates the epileptogenic process
Soon-Tae Lee, Kon Chu, Keun-Hwa Jung, Seung U Kim, Manho Kim and Jae-Kyu Roh
J Cereb Blood Flow Metab 25: S236-S236; doi:10.1038/sj.jcbfm.9591524.0236
Cerebral blood flow SPET and response to acetazolamide challenge in premature craniosynostosis before and after surgery
Mayuki Uchiyama, Hiroshi Nishimoto, Kumiko Nozawa and Eiji Oguma
J Cereb Blood Flow Metab 25: S237-S237; doi:10.1038/sj.jcbfm.9591524.0237
Therapeutic induction of resistance vessels growth increases blood supply in hypoperfused rat brain after treatment with granulocyte-macrophage colony-stimulating factor
Johannes Woitzik, Ulf Schneider, Helmuth Schroeck and Lothar Schilling
J Cereb Blood Flow Metab 25: S238-S238; doi:10.1038/sj.jcbfm.9591524.0238
Minocycline enhances neurogenesis and functional recovery after stroke injury
Zhengyan Liu, Yang Fan, Shwuhuey M Hong and Jialing Liu
J Cereb Blood Flow Metab 25: S239-S239; doi:10.1038/sj.jcbfm.9591524.0239
Spatio-temporal patterns of MRI-detected manganese-enhancement in the sensorimotor network of rat brain after stroke
Jet van der Zijden, Ona Wu, Annette van der Toorn and Rick M Dijkhuizen
J Cereb Blood Flow Metab 25: S240-S240; doi:10.1038/sj.jcbfm.9591524.0240
Spatial differences of neuronal cell proliferation after focal ischemia: Neurogenesis is enhanced in dentate gyrus, but suppressed in the subventricular zone
Ansgar M Brambrink, Yulia Ivashkova, Kamila Vagnerova, Wenri Zhang and Patrica D Hurn
J Cereb Blood Flow Metab 25: S241-S241; doi:10.1038/sj.jcbfm.9591524.0241
Long-term motor deficit following periventricular hemorrhage in neonatal rats: A potential model for human cerebral palsy
Janani Balasubramaniam, Menghzou Xue and Marc Del Bigio
J Cereb Blood Flow Metab 25: S242-S242; doi:10.1038/sj.jcbfm.9591524.0242
Indomethacin decreases immune cell activation and improves cell survival and neurogenesis following stroke, but does not improve functional recovery
Benjamin D Hoehn, Theo D Palmer, Dave W Schaal and Gary K Steinberg
J Cereb Blood Flow Metab 25: S243-S243; doi:10.1038/sj.jcbfm.9591524.0243
Hematopoietic cytokines induce regeneration in mouse brain after stroke
Shunya Takizawa, Hiroshi Kawada, Mitsuyo Tsuma, Tomomi Takanashi, Yuko Morita, Tsuyoshi Uesugi, Tomomitsu Hotta, Shigeharu Takagi and Yukito Shinohara
J Cereb Blood Flow Metab 25: S244-S244; doi:10.1038/sj.jcbfm.9591524.0244
White Matter, Brain Edema, Blood Brain Barrier
Oral session
Oral session
Assessment of the blood-to-brain transfer constant for Gd-DTPA in ischemic brain tissue: Comparison of MRI and QAR methods using a continuous infusion procedure
Robert A Knight, Tavarekere N Nagaraja, Vijaya Nagesh, James R Ewing, Polly A Whitton, Kelly A Keenan, Susan C Fagan and Joseph D Fenstermacher
J Cereb Blood Flow Metab 25: S245-S245; doi:10.1038/sj.jcbfm.9591524.0245
Brain aquaporin 9 (AQP9) regulation by systemic insulin in rat
Jerome Badaut, Jean-Marie Petit, Jean-François Brunet, Pierre J Magistretti and Luca Regli
J Cereb Blood Flow Metab 25: S246-S246; doi:10.1038/sj.jcbfm.9591524.0246
Postischemic hypothermia protects against loss of agrin and SPARC from the vascular basement membrane in global cerebral ischemia
Danica Stanimirovic, Ewa Baumann, Edward Preston, Ingolf Blasig and Reiner Haseloff
J Cereb Blood Flow Metab 25: S247-S247; doi:10.1038/sj.jcbfm.9591524.0247
Vascular permeability may spatially predict subsequent hemorrhages in stroke-prone spontaneous hypertensive rats
Guihua Zhai, Weili Lin, Qingwei Liu, Liansheng Chang and Jin-Moo Lee
J Cereb Blood Flow Metab 25: S248-S248; doi:10.1038/sj.jcbfm.9591524.0248
Malignant brain edema after MCA infarction is determined by the severity of ischemia within the infarction
Bert Bosche, Christian Dohmen, Rudolf Graf, Norbert Galldiks, Jan Sobesky, Lutz Kracht, Fritz G Lehnhardt and Wolf-Dieter Heiss
J Cereb Blood Flow Metab 25: S249-S249; doi:10.1038/sj.jcbfm.9591524.0249
Characterization of vascular protein expression patterns in cerebral ischemia/reperfusion using laser capture microdissection and ICAT-LC-MS/MS
Arsalan Haqqani, Ewa Baumann, Edward Preston, John Kelly and Danica Stanimirovic
J Cereb Blood Flow Metab 25: S250-S250; doi:10.1038/sj.jcbfm.9591524.0250
Oral session
Poster Session
Chronic blood-brain barrier insufficiency and cytotoxic fragment of amyloid precursor protein activity in white matter following ischemia-reperfusion brain injury in long-lived animals
Ryszard Pluta, S
awomir Januszewski and Marzena Uamek
J Cereb Blood Flow Metab 25: S251-S251; doi:10.1038/sj.jcbfm.9591524.0251
Glial activation in white matter injury following ischemia in the neonatal P7 rat brain
Valerie Biran, Luc-Marie Joly, Jean Mariani, Sylvain Renolleau and Christiane Charriaut-Marlangue
J Cereb Blood Flow Metab 25: S252-S252; doi:10.1038/sj.jcbfm.9591524.0252
Absence of the mdr1a P-glycoprotein in mice shows neuroprotection in transient focal cerebral ischemia
Michihiro Murozono, Shohei Matsumoto, Naoko Takeda, Mao Miyamoto and Seigo Watanabe
J Cereb Blood Flow Metab 25: S253-S253; doi:10.1038/sj.jcbfm.9591524.0253
A role of astrocytic aquaporin4 on the traumatic brain edema and a hypothermic effect upon the aquaporin4 expression
Akira Watanabe, Kazuo Kataoka, Kiyoshi Tsuji, Toshihisa Sumii, Yoshifumi Teramoto and Mamoru Taneda
J Cereb Blood Flow Metab 25: S254-S254; doi:10.1038/sj.jcbfm.9591524.0254
Cardiac arrest induces vascular endothelial leakage in the brain stem
Jeff W M Bulte, Julia Kofler, Jiangyang Zhang, Susumu Mori and Richard J Traystman
J Cereb Blood Flow Metab 25: S255-S255; doi:10.1038/sj.jcbfm.9591524.0255
Intracerebral hemorrhage in complement C3 deficient and sufficient mice
Shuxu Yang, Takehiro Nakamura, Ya Hua, Richard Keep, John Younger, Julian Hoff and Guohua Xi
J Cereb Blood Flow Metab 25: S256-S256; doi:10.1038/sj.jcbfm.9591524.0256
Blood brain barrier impairment in the stroke-prone spontaneously hypertensive rat (SHRSP) 28 days after stroke
Jetta K McGill, David I Graham, William Stewart, Elaine I Irving, Anna F Dominiczak and I Mhairi Macrae
J Cereb Blood Flow Metab 25: S257-S257; doi:10.1038/sj.jcbfm.9591524.0257
Microvascular basal lamina damage after subarachnoid hemorrhage (SAH) in rats
Karsten Schöller, Andreas Trinkl, Mariusz Klopotowski, Serge Thal, Nikolaus Plesnila, Robert Schmid-Elsaesser and Stefan Zausinger
J Cereb Blood Flow Metab 25: S258-S258; doi:10.1038/sj.jcbfm.9591524.0258
Time course of edema formation and brain aquaporin expression after transient focal cerebral ischemia in mice
Marlise de Castro Ribeiro, Lorenz Hirt, Julien Bogousslavsky, Luca Regli and Jerome Badaut
J Cereb Blood Flow Metab 25: S259-S259; doi:10.1038/sj.jcbfm.9591524.0259
Recurrent spreading depression (SD) causes early opening of the blood-brain barrier (BBB)
Sebastian Major, Alon Friedman and Jens P Dreier
J Cereb Blood Flow Metab 25: S260-S260; doi:10.1038/sj.jcbfm.9591524.0260
Effect of Boswellia carterii on brain edema following contusion injury
Martin U Schuhmann, Maryam Mokhtarzardeh, Marco Skardelly, Matthias Jaeger, Frank M Gutzki and Dirk O Stichtenoth
J Cereb Blood Flow Metab 25: S261-S261; doi:10.1038/sj.jcbfm.9591524.0261
Accumulation of 4-hydroxy-2-nonenal-modified proteins in the white matter damage in chronic cerebral hypo-perfusion rat mode
Terubumi Watanabe, Yoshiko Yanagi, Takao Urabe and Yoshikuni Mizuno
J Cereb Blood Flow Metab 25: S262-S262; doi:10.1038/sj.jcbfm.9591524.0262
Chronic cerebral hypoperfusion induces white matter lesions and cognitive abnormalities; a comparison between mouse and rat models for vascular dementia
Hidekazu Tomimoto, Masunari Shibata, Kayoko Nakaji, Masafumi Ihara, Makoto Noda, Nobuyuki Yamasaki and Tsuyoshi Miyakawa
J Cereb Blood Flow Metab 25: S263-S263; doi:10.1038/sj.jcbfm.9591524.0263
Activation of Rho/Rho kinase system after focal cerebral ischemia
Yoshiki Yagita, Kazuo Kitagawa, Tsutomu Sasaki, Shiro Sugiura, Kenichi Todo, Emi Omura-Matsuoka, Kohji Matsushita and Masatsugu Hori
J Cereb Blood Flow Metab 25: S264-S264; doi:10.1038/sj.jcbfm.9591524.0264
Na-K-2Cl cotransporters contributes to IL-1-induced neuronal damage during traumatic brain injury
Kwok-Tung Lu, Chang-Yen Wu and Yi-Ling Yang
J Cereb Blood Flow Metab 25: S265-S265; doi:10.1038/sj.jcbfm.9591524.0265
Hyperbaric oxygen reduces blood-brain barrier damage and edema after transient focal cerebral ischemia
Roland Veltkamp, Li Sun, Dirk A Siebing, Katja Bieber, Sabine Heiland, Hugo H Marti, Stefan Schwab and Markus Schwaninger
J Cereb Blood Flow Metab 25: S266-S266; doi:10.1038/sj.jcbfm.9591524.0266
Delayed chronic endothelial damage after brief global forebrain ischemia in the rat
Baowan Lin, Weizhao Zhao, Raul J Busto and Myron D Ginsberg
J Cereb Blood Flow Metab 25: S267-S267; doi:10.1038/sj.jcbfm.9591524.0267
MRI measures of changes in the transfer constant of gadomer after dexamethasone in 9L rat cerebral tumor
James R Ewing, Stephen R Brown, Jamie R Churchman, Swayamprava R Panda, Ramesh R Paudyal and Joseph R Fenstermacher
J Cereb Blood Flow Metab 25: S268-S268; doi:10.1038/sj.jcbfm.9591524.0268
Barrier distruption following excitotoxic lesions in the brain of the anaesthetized rat
Jérôme Toutain, Xavier Jaglin, Didier Divoux, Laurent Chazalviel, Omar Touzani and Eric T MacKenzie
J Cereb Blood Flow Metab 25: S269-S269; doi:10.1038/sj.jcbfm.9591524.0269
Role of arginine vasopressin V1 and V2 receptors for brain damage after transient focal cerebral ischemia
Abedin Vakili, Hiroharu Kataoka and Nikolaus Plesnila
J Cereb Blood Flow Metab 25: S270-S270; doi:10.1038/sj.jcbfm.9591524.0270
Evolution of brain edema after subarachnoid hemorrhage (SAH) in rats
Serge C Thal, Sonja Sporer, Nikolaus Plesnila, Karsten Schoeller, Robert Schmid-Elsaesser and Stefan Zausinger
J Cereb Blood Flow Metab 25: S271-S271; doi:10.1038/sj.jcbfm.9591524.0271
Mast cell blocking improves outcome after experimental intracerebral hemorrhage
Daniel Strbian, Turgut Tatlisumak, Marja-Liisa Karjalainen-Lindsberg, Usama Abo-Ramadan and Perttu J Lindsberg
J Cereb Blood Flow Metab 25: S272-S272; doi:10.1038/sj.jcbfm.9591524.0272
Effect of age on blood brain barrier transport function studied with [11C](R)-verapamil and PET
Jan R Toornvliet, Bart N M van Berckel, Gert Luurtsema, Mark Lubberink, Ab A Geldof, Tessa M Bosch, Adriaan A Lammertsma and Eric J F Franssen
J Cereb Blood Flow Metab 25: S273-S273; doi:10.1038/sj.jcbfm.9591524.0273
Ultraearly reperfusion induces blood brain barrier disruption during focal ischemia in rats
Johannes Woitzik, Axel Hohenstein, Nina Weinzierl and Lothar Schilling
J Cereb Blood Flow Metab 25: S274-S274; doi:10.1038/sj.jcbfm.9591524.0274
Novel role of 'entourage' monoacylglycerols in function of human cerebral microvascular endothelial cells
Richard McCarron, Esther Shohami, Ye Chen, Alois Strasser, Raphael Mechoulam, Joliet Bembry and Maria Spatz
J Cereb Blood Flow Metab 25: S275-S275; doi:10.1038/sj.jcbfm.9591524.0275
RLIP-76: A novel mechanism of drug resistance in epilepsy
Kerri L Mancini, Vince Fazio, Sanjay Awasthi, Sharad Singhal, Luca Cucullo, Gabriele Dini and Damir Janigro
J Cereb Blood Flow Metab 25: S276-S276; doi:10.1038/sj.jcbfm.9591524.0276
In a rat model of transient ischemia, acute albumin leakage across the blood-brain barrier is often followed by rapid cellular uptake
Tavarekere N Nagaraja, Kelly A Keenan, Joseph D Fenstermacher and Robert A Knight
J Cereb Blood Flow Metab 25: S277-S277; doi:10.1038/sj.jcbfm.9591524.0277
Proteomics analysis in transgenic mice over-expressing endothelin-1 in astrocytes after transient focal cerebral ischemia
Amy C Y Lo, Marco M K Tsui, Victor K L Hung, Lai Ping Yaw, Qing-Yu He, Jen-Fu Chiu, Stephen S M Chung and Sookja K Chung
J Cereb Blood Flow Metab 25: S278-S278; doi:10.1038/sj.jcbfm.9591524.0278
Partial replacement of K+ with RB+ in the rat brain in vivo does not change the tissue potassium dynamics after focal cerebral ischemia and is detectable by 87Rb MRI
Victor E Yushmanov, Alexander Kharlamov, Eli J Wasserman, Fernando E Boada and Stephen C Jones
J Cereb Blood Flow Metab 25: S279-S279; doi:10.1038/sj.jcbfm.9591524.0279
PET Methods for Alzheimer's Disease
Oral session
Oral session
Correlation of regional cerebral amyloid load in Alzheimer's disease, measured with [11C]-PIB pet using spectral analysis and tissue uptake ratios, with Performance on recognition memory tests
Paul Edison, Hilary Archer, Rainer Hinz, Alexander Hammers, Alexander Gerhard, Nicola Pavese, Yen Tai, Gary Hotton, Dawn Cuttler, Nick Fox, Martin Rossor and David J Brooks
J Cereb Blood Flow Metab 25: S591-S591; doi:10.1038/sj.jcbfm.9591524.0591
Animal PET Methodology
Oral session
Noninvasive measurements of CBF and CMRO2 in the rat brain using microPET imaging
Seong-Hwan Yee and Peter T Fox
J Cereb Blood Flow Metab 25: S600-S600; doi:10.1038/sj.jcbfm.9591524.0600
Measurement of regional rates of cerebral protein synthesis with L-[1-11C]leucine and PET with correction for recycling of tissue amino acids: Comparison of region of interest and voxel-based analyses
Kathleen C Schmidt and Carolyn Beebe Smith
J Cereb Blood Flow Metab 25: S601-S601; doi:10.1038/sj.jcbfm.9591524.0601
Development of longitudinal PET studies for experimental animal models
Lia C Liefaard, Bart A Ploeger, Carla F M Molthoff, Ronald Boellaard, Hugo W A M de Jong, Adriaan A Lammertsma, Meindert Danhof and Rob A Voskuyl
J Cereb Blood Flow Metab 25: S602-S602; doi:10.1038/sj.jcbfm.9591524.0602
Imaging post-ischaemic cellular changes using 11C-flumazenil & microPET following temporary distal MCA occlusion in the spontaneous hypertensive rat (SHR)
Jessica L Hughes, John S Beech, Tim D Fryer, Rob Smith, Oksana Golovko, Marcel Cleij, Franklin I Aigbirhio, David K Menon, John C Clark and Jean-Claude Baron
J Cereb Blood Flow Metab 25: S603-S603; doi:10.1038/sj.jcbfm.9591524.0603
Dopamine D2/3 receptor binding in aphakia mice measured by microPET
Pedro Rosa-Neto, Andrew L Goertzen, Mirko Diksic, Alain Dagher, Shadrek Mzengeza, Jean-Paul Soucy, Kelvin C Luk, Vladimir Rymar, Abbas F Sadikot and Alan C Evans
J Cereb Blood Flow Metab 25: S604-S604; doi:10.1038/sj.jcbfm.9591524.0604
BRAINPET
Oral session
Poster Session
Glucose metabolism in distinct human midbrain nuclei and correlations with other brain regions
Karl Herholz, Klaus Wienhard, Jiri Cizek, Alexander Thiel, Stefan Vollmar, Johannes Klein and Wolf-Dieter Heiss
J Cereb Blood Flow Metab 25: S618-S618; doi:10.1038/sj.jcbfm.9591524.0618
Quantitative accuracy of the High Resolution Research Tomograph: Experimental and clinical evaluation
Hugo W A M de Jong, Ronald Boellaard, Bart N M van Berckel, Mirthe M Ponsen and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S619-S619; doi:10.1038/sj.jcbfm.9591524.0619
Interactive fuzzy temporal thresholding for the segmentation of dynamic brain PET images
Jinman Kim, Weidong Cai, Dagan Feng and Stefan Eberl
J Cereb Blood Flow Metab 25: S620-S620; doi:10.1038/sj.jcbfm.9591524.0620
Comparison of two methods for correction of partial volume effects in PET
Elena Rota Kops and Anthonin Reihlac
J Cereb Blood Flow Metab 25: S621-S621; doi:10.1038/sj.jcbfm.9591524.0621
Motion correction eliminates discontinuities in parametric PET images of neuroreceptor binding
Hans R Herzog, Lutz Tellmann, Roger Fulton, Isabelle Stangier, Elena Rota Kops, Kay Bente and Uwe Pietrzyk
J Cereb Blood Flow Metab 25: S622-S622; doi:10.1038/sj.jcbfm.9591524.0622
Active contour based efficient registration for biomedical brain images
Xiuying Wang and David D Feng
J Cereb Blood Flow Metab 25: S623-S623; doi:10.1038/sj.jcbfm.9591524.0623
Predicting drug concentrations in brain using positron emission tomography and venous input: Modeling of arterial-venous concentration differences
Stina Syvänen, Gunnar Blomquist, Lieuwe Appel, Margareta Hammarlund-Udenaes, Bengt Långström and Mats Bergström
J Cereb Blood Flow Metab 25: S624-S624; doi:10.1038/sj.jcbfm.9591524.0624
Generalization of a physiological model of input function for PET data analysis
Koon-Pong Wong and David D Feng
J Cereb Blood Flow Metab 25: S625-S625; doi:10.1038/sj.jcbfm.9591524.0625
Inhibition of in vivo defluorination of [18F]FCWAY in rat
Dnyanesh N Tipre, Sami S Zoghbi, Jeih-San Liow, Michael V Green, Jurgen Seidel, Masanori Ichise, Victor W Pike and Robert B Innis
J Cereb Blood Flow Metab 25: S626-S626; doi:10.1038/sj.jcbfm.9591524.0626
Performance of MAP-Bayesian methods for managing loss of metabolite samples in PET ligand studies
Mary E Spilker, Gjermund Henriksen, Till Sprenger, Michael Valet, Isabelle Stangier, Hans-J Wester, Thomas R Toelle and Henning Boecker
J Cereb Blood Flow Metab 25: S627-S627; doi:10.1038/sj.jcbfm.9591524.0627
Gender dependent rate of metabolism of the opioid receptor–PET ligand F-18-fluoroethyl-diprenorphine
Gjermund Henriksen, Mary E Spilker, Till Sprenger, Stefan Platzer, Achim Berthele, Thomas R Toelle, Henning Boecker, Markus Schwaiger and Hans-Juergen Wester
J Cereb Blood Flow Metab 25: S628-S628; doi:10.1038/sj.jcbfm.9591524.0628
Multi-input spectral analysis for evaluation of the contribution of radioactive metabolites in (R)-[11C]verapamil PET data
Mark Lubberink, Gert Luurtsema, Ronald Boellaard and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S629-S629; doi:10.1038/sj.jcbfm.9591524.0629
Impact of unmetabolized tracer function modeling on quantification of [carbonyl-11C]WAY-100635 PET images
Valentina Bovo, Alessandra Bertoldo and Claudio Cobelli
J Cereb Blood Flow Metab 25: S630-S630; doi:10.1038/sj.jcbfm.9591524.0630
Generating parametric binding potential and volume of distribution images using a novel 2D basis function method and the two tissue compartment plasma input model
Ronald Boellaard, Marc A Kropholler, Bart N M van Berckel and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S631-S631; doi:10.1038/sj.jcbfm.9591524.0631
Clustering approach for voxel-based Logan plot to improve noise reduction capability
Yuichi Kimura, Jyunnichi Yano, Mihoko Tsukahara, Mika Naganawa, Kenji Ishii and Kiichi Ishiwata
J Cereb Blood Flow Metab 25: S632-S632; doi:10.1038/sj.jcbfm.9591524.0632
Kinetic parametric analysis for feature extraction in FDOPA-PET study
Ren-Shyan Liu, Hong-Dun Lin and Kang-Ping Lin
J Cereb Blood Flow Metab 25: S633-S633; doi:10.1038/sj.jcbfm.9591524.0633
Spectral analysis with a minimal basis functions approach for quantification of ligand-receptor dynamic PET study
Yun Zhou, Weiguo Ye, James R Brasic, Mohab Alexander, John Hilton and Dean F Wong
J Cereb Blood Flow Metab 25: S634-S634; doi:10.1038/sj.jcbfm.9591524.0634
Functional logistic regression with PET imaging data: A voxel-level clinical diagnostic tool
Philip T Reiss, R Todd Ogden, J John Mann and Ramin V Parsey
J Cereb Blood Flow Metab 25: S635-S635; doi:10.1038/sj.jcbfm.9591524.0635
Mixture modeling for PET neuroreceptor studies
Huiping Jiang, R Todd Ogden, J John Mann and Ramin V Parsey
J Cereb Blood Flow Metab 25: S636-S636; doi:10.1038/sj.jcbfm.9591524.0636
A framework of incorporating variance estimates into wavelet analysis in PET metabolism and receptor studies
John A D Aston, Hong-Ren Su, Roger N Gunn and Federico E Turkheimer
J Cereb Blood Flow Metab 25: S637-S637; doi:10.1038/sj.jcbfm.9591524.0637
Integration of PET compartmental models and wavelet analysis techniques: A feasibility study
Hong-Ren Su, John A D Aston, Michelle Liou, Philip E Cheng and Federico E Turkheimer
J Cereb Blood Flow Metab 25: S638-S638; doi:10.1038/sj.jcbfm.9591524.0638
Optimization of wavelet processing of dynamic PET data
Nathaniel M Alpert, Anthonin Reihlac, Tat T Chio and Ivan Selesnick
J Cereb Blood Flow Metab 25: S639-S639; doi:10.1038/sj.jcbfm.9591524.0639
Improving accuracy and precision of PET pharmacokinetic analysis using wavelet based denoising of time activity curves
Maqsood Yaqub, Ronald Boellaard, Marc Kropholler, Mark Lubberink and Adriaan Lammertsma
J Cereb Blood Flow Metab 25: S640-S640; doi:10.1038/sj.jcbfm.9591524.0640
Binding potential underestimation with reference tissue models: Insight from [carbonyl-11C]WAY-100635 simulation studies
Valentina Bovo, Alessandra Bertoldo and Claudio Cobelli
J Cereb Blood Flow Metab 25: S641-S641; doi:10.1038/sj.jcbfm.9591524.0641
Evaluation of reference tissue models for analysing [11C](R)-PK11195 studies
Marc A Kropholler, Bart N M van Berckel, Alie Schuitemaker, Hedy Folkersma, Gert Luurtsema, Albert D Windhorst, Ronald Boellaard and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S642-S642; doi:10.1038/sj.jcbfm.9591524.0642
Effects of reference tissue versus plasma input parametric kinetic modelling on statistical parametric analysis of [11C](R)-PK11195 binding in Alzheimer's disease (AD) and young and old subjects
Alie Schuitemaker, Bart N M van Berckel, Marc A Kropholler, Philip Scheltens, Cees Jonker, Dick J Veltman, Adriaan A Lammertsma and Ronald Boellaard
J Cereb Blood Flow Metab 25: S643-S643; doi:10.1038/sj.jcbfm.9591524.0643
Monte Carlo simulation for reference tissue-based linear analysis of [11C]MP4A AND [11C]MP4P: Assessment of optimal regions and optimization for precise measurement of brain AChE activity
Koichi Sato, Kiyoshi Fukushi, Hitoshi Shinotoh, Shin-ichiro Nagatsuka, Noriko Tanaka, Tsuneyoshi Ota, Tetsuya Shiraishi, Shigeki Hirano, Shuji Tanada, Hiroki Namba, Masaomi Iyo and Toshiaki Irie
J Cereb Blood Flow Metab 25: S644-S644; doi:10.1038/sj.jcbfm.9591524.0644
A generalized reference tissue model for quantification of dynamic PET with bolus plus continuous infusion tracer administration and pharmacological challenge
Yun Zhou, Weiguo Ye, Mingkai Chen, Anil Kumar, Mohab Alexander, Christopher J Endres, Tomas R Guilarte and Dean F Wong
J Cereb Blood Flow Metab 25: S645-S645; doi:10.1038/sj.jcbfm.9591524.0645
Effect of amphetamine on dopamine D2 receptor binding in the primate brain with the agonist ligand [11C]MNPA
Nicholas Seneca, Sjoerd Finnema, Masanori Ichise, Balazs Gulyas, Håkan Wikstrom, Robert B Innis, Lars Farde and Christer Halldin
J Cereb Blood Flow Metab 25: S646-S646; doi:10.1038/sj.jcbfm.9591524.0646
[11C]raclopride imaging of dopamine release in rhesus monkeys
Alexander K Converse, Todd E Barnhart, Corinne B Dallas, Salma Jivan, Julie A Larson, Terrence R Oakes, Andrew D Roberts, Thomas J Ruth, Nicholas T Vandehey and Mary L Schneider
J Cereb Blood Flow Metab 25: S647-S647; doi:10.1038/sj.jcbfm.9591524.0647
Displacement detectability of [18F]MPPF from 5-HT1A receptors by endogenous serotonin: A monte carlo simulation study
Nicolas Costes, Anthonin Reilhac, Axel Martinez and Isabelle Merlet
J Cereb Blood Flow Metab 25: S648-S648; doi:10.1038/sj.jcbfm.9591524.0648
Quantifying in vivo dopaminergic D2-receptors Bmax and KdVr with microPET® focus after a single injection of [11C]raclopride
Laurent Besret, Jean-Dominique Gallezot, Frédéric Dollé, Philippe Hantraye and Marie-Claude Grégoire
J Cereb Blood Flow Metab 25: S649-S649; doi:10.1038/sj.jcbfm.9591524.0649
Measuring the integrity of the dopamine system in rats with [11C]dihydrotetrabenazine: MicroPET vs phosphor imaging autoradiography
Elissa M Strome, Ivan L Cepeda and Doris J Doudet
J Cereb Blood Flow Metab 25: S650-S650; doi:10.1038/sj.jcbfm.9591524.0650
Evaluation of the serotonin transporter ligand [123I]ADAM for SPECT studies in humans
Vibe G Frokjaer, Lars H Pinborg, Jacob Madsen and Gitte M Knudsen
J Cereb Blood Flow Metab 25: S651-S651; doi:10.1038/sj.jcbfm.9591524.0651
Use of an [18F]setoperone bolus + infusion protocol to delineate age related reduction in 5HT2A receptor binding potential in female rhesus monkeys
Wai-Si Eng, Stephen Krause, Christine Ryan, Holly Sleph, Maria Michener, Marie Holahan, Eric Hostetler, Liza Gantert, Marie-Jose Belanger, Daniel Rubins, Sandra Sanabria, Richard Hargreaves, Jacquelynn Cook and H Donald Burns
J Cereb Blood Flow Metab 25: S652-S652; doi:10.1038/sj.jcbfm.9591524.0652
Test-retest measurements of 5-HT2A receptors with [18F]altanserin PET
Steven Haugbøl, Gitte M Knudsen, Vibe G Frøkjær, Steen G Hasselbalch and Lars H Pinborg
J Cereb Blood Flow Metab 25: S653-S653; doi:10.1038/sj.jcbfm.9591524.0653
Synthesis of N-methyl-2-(2-amino-4-[18F]fluorophenylthio)benzylamine as serotonin transporter imaging agent
Grace G Shiue, Joel H Greenberg and Chyng-Yann Shiue
J Cereb Blood Flow Metab 25: S654-S654; doi:10.1038/sj.jcbfm.9591524.0654
[123I]TPCNE: A novel SPET tracer for the sigma-1 receptor binds irreversibly in humans in vivo
James M Stone, Erik Arstad, Kjell Erlandsson, Rikki N Waterhouse, Peter J Ell and Lyn S Pilowsky
J Cereb Blood Flow Metab 25: S655-S655; doi:10.1038/sj.jcbfm.9591524.0655
[123I]TPCNE: A novel SPET tracer for the sigma-1 receptor is displaceable in humans in vivo with low dose oral haloperidol
James M Stone, Kjell Erlandsson, Erik Arstad, Rikki N Waterhouse, Peter J Ell and Lyn S Pilowsky
J Cereb Blood Flow Metab 25: S656-S656; doi:10.1038/sj.jcbfm.9591524.0656
Evaluation of [11C](-)-O-methylvesamicol as a PET ligand for mapping vesicular acetylcholine transporters
Kiichi Ishiwata, Kazunori Kawamura, Hideo Tsukada, Shingo Nishiyama, Yuichi Kimura and Kazuhiro Shiba
J Cereb Blood Flow Metab 25: S657-S657; doi:10.1038/sj.jcbfm.9591524.0657
In vivo evaluation of [11C]TMSX and [11C]KF21213 for mapping adenosine A2A receptors: Brain kinetics in the conscious monkey and P-glycoprotein modulation in the mouse brain
Kiichi Ishiwata, Hideo Tsukada, Yuichi Kimura, Kazunori Kawamura, Norihiro Harada and Harry H Hendrikse
J Cereb Blood Flow Metab 25: S658-S658; doi:10.1038/sj.jcbfm.9591524.0658
Distribution of adenosine A2A receptors in human brain using [C-11]TMSX PET
Masahiro Mishina, Kiichi Ishiwata, Kenji Ishii, Yuichi Kimura, Kazunori Kawamura, Keiichi Oda, Toru Sasaki, Shiro Kobayashi and Yasuo Katayama
J Cereb Blood Flow Metab 25: S659-S659; doi:10.1038/sj.jcbfm.9591524.0659
Comparison of various models for analysing [11C]flumazenil studies
Ursula M H Klumpers, Dick J Veltman, Emile F I Comans, Marc A Kropholler, Ronald Boellaard, Witte J G Hoogendijk and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S660-S660; doi:10.1038/sj.jcbfm.9591524.0660
SPECT quantification of benzodiazepine receptor concentration and ligand affinity using a dual-ligand approach
Philippe Millet, Marcelle Moulin-Sallanon and Vicente Ibáñez
J Cereb Blood Flow Metab 25: S661-S661; doi:10.1038/sj.jcbfm.9591524.0661
Quantification of brain phosphodiesterase 4 in rats using [11C]rolipram PET after antidepressant treatment
Masahiro Fujita, Masao Imaizumi, Sami S Zoghbi, Matthew S Crescenzo, Jinsoo Hong, John L Musachio, Jian Q Lu, Vanessa L Cropley, Jeih S Liow, Antony D Gee, Jurgen Seidel, Michael V Green, Victor W Pike, Ronald S Duman and Robert B Innis
J Cereb Blood Flow Metab 25: S662-S662; doi:10.1038/sj.jcbfm.9591524.0662
Investigation of acute modulation of cAMP in vivo with PET using [11C]rolipram
Christine A Parker, Julian C Matthews, Roger N Gunn, Laurent Martarello, Vincent J Cunningham, Dirk Bender, Steen Jakobsen, Svend B Jensen, Stephen T Knibb and Antony D Gee
J Cereb Blood Flow Metab 25: S663-S663; doi:10.1038/sj.jcbfm.9591524.0663
Characterizing the optimal acquisition duration of [18F]fluoroethyl-diprenorphine PET studies
Henning Boecker, Till Sprenger, Germund Henriksen, Isabelle Stangier, Hans J Wester, Thomas R Toelle and Mary E Spilker
J Cereb Blood Flow Metab 25: S664-S664; doi:10.1038/sj.jcbfm.9591524.0664
Towards improved test-retest reliability in quantitative ligand PET: [11C]Diprenorphine as an example
Alexander Hammers, Marie-Claude Asselin, Safiye Osman, Rainer Hinz, Federico Turkheimer, Gary Hotton, David J Brooks, John S Duncan and Matthias J Koepp
J Cereb Blood Flow Metab 25: S665-S665; doi:10.1038/sj.jcbfm.9591524.0665
Different patterns of PIB uptake in AD patients
Gunnar Blomquist, Rainer Hinz, Henry Engler, Agneta Nordberg and Bengt Långström
J Cereb Blood Flow Metab 25: S666-S666; doi:10.1038/sj.jcbfm.9591524.0666
Quantification in vivo of nicotinic acetylcholine receptors density and affinity in the baboon brain using 2-[18F]fluoro-A-85380 and a multi-injection approach
Jean-Dominique Gallezot, Marie-Claude Grégoire, Michel Bottlaender, Dollé Frédéric, Saba Wadad, Christine Coulon, Michèle Ottaviani, Jacques Delforge, André Syrota and Héric Valette
J Cereb Blood Flow Metab 25: S667-S667; doi:10.1038/sj.jcbfm.9591524.0667
Inhibition of metabolic steps in serotonin biosynthesis: PET studies with [11C]-5-Hydroxy-L-tryptophan
Pinelopi Lundquist, Gunnar Blomquist, Per Hartvig and Bengt Långström
J Cereb Blood Flow Metab 25: S668-S668; doi:10.1038/sj.jcbfm.9591524.0668
Visualization of correlated neural and metabolic functions in temporal lobe epilepsy by a correlation analysis with multiple PET studies
Ikuma Takahashi, Tadashi Nariai, Koji Uemura, Taketoshi Maehara, Kenji Ishii, Akihiko Uchiyama and Hinako Toyama
J Cereb Blood Flow Metab 25: S669-S669; doi:10.1038/sj.jcbfm.9591524.0669
Quantitative measurement of cerebral metabolic rate of glucose by means of dual-head coincidence gamma camera and 2-deoxy-2- [18F] fluoro-D-glucose
Katsufumi Kajimoto, Naohiko Oku, Yasuyuki Kimura, Makiko Tanaka, Hiroki Kato, Kazuo Kitagawa, Masatsugu Hori and Jun Hatazawa
J Cereb Blood Flow Metab 25: S670-S670; doi:10.1038/sj.jcbfm.9591524.0670
Feasibility of deriving CBF, OEF and CMRO2 from a single dynamic PET scan using a short inhalation of oxygen-15 labelled molecular oxygen
Ronald Boellaard, Abraham Rijbroek, Gert Luurtsema, Henri N J M Greuter and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S671-S671; doi:10.1038/sj.jcbfm.9591524.0671
Rapid CBF/CMRO2 measurement in a single PET scan with dual tracer administration
Nobuyuki Kudomi, Takuya Hayashi, Hiroshi Watabe and Hidehiro Iida
J Cereb Blood Flow Metab 25: S672-S672; doi:10.1038/sj.jcbfm.9591524.0672
Estimation of 15O PET in healthy volunteers with automated ROI analysis by FineSRT
Ryo Takeuchi, Keiichi Matsumoto, Setsu Sakamoto, Yuhji Nakamoto and Michio Senda
J Cereb Blood Flow Metab 25: S673-S673; doi:10.1038/sj.jcbfm.9591524.0673
Development of sinogram-based estimation method of delay time of arterial input function with O-15 tracer and PET study
Hiroshi Watabe, Nobuyuki Kudomi, Takuya Hayashi and Hidehiro Iida
J Cereb Blood Flow Metab 25: S674-S674; doi:10.1038/sj.jcbfm.9591524.0674
Sources of variability in oxygen-15 PET studies in acute brain injury – impact on sample size estimation
Jonathan P Coles, Tim D Fryer, Peter G Bradley, Jurgens Nortje, Peter Smielewski, Kenneth Rice, John C Clark, John D Pickard and David K Menon
J Cereb Blood Flow Metab 25: S675-S675; doi:10.1038/sj.jcbfm.9591524.0675
Cerebral vascular mean transit time determined by PET and DSC-MRI
Masanobu Ibaraki, Hiroshi Ito, Eku Shimosegawa, Hideto Toyoshima, Keiichi Ishigame, Kazuhiro Takahashi, Syuichi Miura and Iwao Kanno
J Cereb Blood Flow Metab 25: S676-S676; doi:10.1038/sj.jcbfm.9591524.0676
Ordered subset expectation maximization algorithm for image reconstruction affects the SPM analysis in patients with mild Alzheimer's disease
Yasuhiro Katsura, Ryohei Matsuura, Yasuhiro Akazawa, Piao Rishu, Ansar M D Ashik, Yasuyuki Kimura, Katsufumi Kajimoto, Naohiko Oku, Shinji Hasegawa and Jun Hatazawa
J Cereb Blood Flow Metab 25: S677-S677; doi:10.1038/sj.jcbfm.9591524.0677
Ordered subset expectation maximization algorithm for image reconstruction applied to zero-flow or low-flow mimicking brain phantom
Yasuhiro Akazawa, Yasuhiro Katsura, Ryohei Matsuura, Piao Rishu, Ansar M D Ashik, Yasuyuki Kimura, Katsufumi Kajimoto, Naohiko Oku, Shinji Hasegawa and Jun Hatazawa
J Cereb Blood Flow Metab 25: S678-S678; doi:10.1038/sj.jcbfm.9591524.0678
Strategy of SPECT reconstruction for absolute quantitation of cerebral function image
Kyeong Min Kim, Hidehiro Iida, Mayumi Nakazawa and Kinuko Abe
J Cereb Blood Flow Metab 25: S679-S679; doi:10.1038/sj.jcbfm.9591524.0679
Defining paramaters for an adaptative 3D Wiener filter in image restoration of SPECT cerebral blood flow studies: A novel approach
Jean-Paul Soucy, Wei Li and Jean Meunier
J Cereb Blood Flow Metab 25: S680-S680; doi:10.1038/sj.jcbfm.9591524.0680
Cell and Gene Therapy
Oral session
Gene therapy for ischemic neuronal injury
Midori A Yenari, Heng Zhao, Robert M Sapolsky and Gary K Steinberg
J Cereb Blood Flow Metab 25: S693-S693; doi:10.1038/sj.jcbfm.9591524.0694
Gene therapy using adenovirus
Takeshi Hayashi
J Cereb Blood Flow Metab 25: S694-S694; doi:10.1038/sj.jcbfm.9591524.0695
Cell replacement therapy after stroke by recruitment of endogenous neural progenitors
Nobutaka Kawahara, Hirofumi Nakatomi, Toshihiko Kuriu, Shigeo Okabe, Akira Tamura, Masato Nakafuku and Taaaki Kirino
J Cereb Blood Flow Metab 25: S695-S695; doi:10.1038/sj.jcbfm.9591524.0696
TAT fusion proteins as innovative treatment strategy in stroke
Ertugrul Kilic
J Cereb Blood Flow Metab 25: S696-S696; doi:10.1038/sj.jcbfm.9591524.0697
Stimulating brain recovery after stroke with cell therapy
Michael Chopp
J Cereb Blood Flow Metab 25: S697-S697; doi:10.1038/sj.jcbfm.9591524.0698
Cerebrovascular Dysfunction in Dementia
Oral session
Functional cerebrovascular abnormalities in CADASIL
Martin Dichgans
J Cereb Blood Flow Metab 25: S698-S698; doi:10.1038/sj.jcbfm.9591524.0699
Transgenic mice modeling CADASIL arteriopathy have impaired cerebrovascular reactivity
Pierre Lacombe, Charleen Oligo, Valérie Domenga, Elisabeth Tournier-Lasserve and Anne Joutel
J Cereb Blood Flow Metab 25: S699-S699; doi:10.1038/sj.jcbfm.9591524.0700
CBF and metabolism in dementia during activation
Marc J Mentis
J Cereb Blood Flow Metab 25: S700-S700; doi:10.1038/sj.jcbfm.9591524.0701
CBF as a diagnostic tool in dementias: Revision required?
Olaf B Paulson
J Cereb Blood Flow Metab 25: S701-S701; doi:10.1038/sj.jcbfm.9591524.0702
Heterogeneity in Cerebral Metabolism and Blood Flow
Oral session
Symposium
Energetic costs associated with glutamatergic and gabaergic neurotransmission
Robin A de Graaf, Anant B Patel, Graeme F Mason, Douglas L Rothman, Robert G Shulman and Kevin L Behar
J Cereb Blood Flow Metab 25: S706-S706; doi:10.1038/sj.jcbfm.9591524.0707
Brain energy metabolism: Role of variable oxygen tensions during neuronal activity
Albert Gjedde and Manouchehr S Vafaee
J Cereb Blood Flow Metab 25: S707-S707; doi:10.1038/sj.jcbfm.9591524.0708
The degree of heterogeneity in metabolic demand and blood flow as measured by PET
Iida Hidehiro, Hayashi Takuya, Watabe Hiroshi, Kudomi Nobuyuki, Piao Rishu, Teramoto Noboru, Youichirou Ota, Koshino Kazuhiro, Enmi Junichiro, Kim Kyeong-Min, Inomata Toru, Zeniya Tsutomu, Sato Sato, Yamamotso Atsushi and Yamauchi Miho
J Cereb Blood Flow Metab 25: S708-S708; doi:10.1038/sj.jcbfm.9591524.0709
No way! O2/NO/blood flow interactions in brain
Donald G Buerk
J Cereb Blood Flow Metab 25: S709-S709; doi:10.1038/sj.jcbfm.9591524.0710
Imaging Neurotransmission with PET
Oral session
PET imaging of DA neurotransmission using agonist versus antagonist radiotracers
Nathalie Ginovart, Matthaeus Willeit, Ariel Graff, Shitij Kapur and Alan A Wilson
J Cereb Blood Flow Metab 25: S715-S715; doi:10.1038/sj.jcbfm.9591524.0716
Human dopamine response to drugs and natural rewards
Alain Dagher
J Cereb Blood Flow Metab 25: S716-S716; doi:10.1038/sj.jcbfm.9591524.0717
Effects of transient reduction of endogenous 5-HT levels on 11C-DASB and 11C-MDL100907 specific binding: Implications for finding a serotonergic radiotracer vulnerable to endogenous competition in humans
Peter S Talbot
J Cereb Blood Flow Metab 25: S717-S717; doi:10.1038/sj.jcbfm.9591524.0718
Can we measure 5-HT release with PET?
Paul M Grasby
J Cereb Blood Flow Metab 25: S718-S718; doi:10.1038/sj.jcbfm.9591524.0719
In Vivo Cell Tracking and Gene Expression
Oral session
Imaging-guided gene therapy of gliomas
Andreas H Jacobs, Maria A Rueger, Alexandra Winkeler, Huongfeng Li, Markus Klein, Matthias Stoeckle, Parisa Monfared, Rudolf Graf, Stefan Vollmar, Klaus Wienhard and Wolf-Dieter Heiss
J Cereb Blood Flow Metab 25: S690-S690; doi:10.1038/sj.jcbfm.9591524.0690
Neuroreceptor expression as surrogate markers for dementias
Gitte M Knudsen
J Cereb Blood Flow Metab 25: S691-S691; doi:10.1038/sj.jcbfm.9591524.0691
Monitoring stem cell migration in the nervous system by in vivo magnetic resonance imaging
Mathias Hoehn, Uwe Himmelreich, Ralph Weber, Pedro Ramos-Cabrer, Susanne Wegener, Dirk Wiedermann and Ekkehard Küstermann
J Cereb Blood Flow Metab 25: S692-S692; doi:10.1038/sj.jcbfm.9591524.0693
Neurotransmitter Release
Oral session
The D2-agonist radiotracer [11C]-(+)-PHNO shows a marked increase in sensitivity to amphetamine challenges when compared to [11C]raclopride in the cat brain
Nathalie Ginovart, Alan A Wilson, Matthaeus Willeit, Ken Singh, Douglas Hussey, Armando Garcia, Sylvain Houle and Shitij Kapur
J Cereb Blood Flow Metab 25: S611-S611; doi:10.1038/sj.jcbfm.9591524.0611
Methodological development of dynamic dopamine release using [18F]desmethoxyfallypride
Todd E Barnhart, Alexander K Converse, Terrence R Oakes, Jonathan A Nye, David W Dick, Dhanabalan Murali, Fabio Ferrarelli, Marchello Massimini, Guilio Tononi, Mary L Schneider, Julie A Larsen, Jogeshwar Mukherjee, Charles K Stone, Onofre T DeJesus, Robert J Nickles and Andrew D Roberts
J Cereb Blood Flow Metab 25: S612-S612; doi:10.1038/sj.jcbfm.9591524.0612
Estimation of receptor occupancy and synaptic dopamine after amphetamine challenge: A competition model approach
Hiroto Kuwabara, Anil Kumar, James Brasic, Ayon Nandi and Dean F Wong
J Cereb Blood Flow Metab 25: S613-S613; doi:10.1038/sj.jcbfm.9591524.0613
Effect of acute systemic baclofen on amphetamine stimulated striatal dopamine release as measured in rats with [3H]raclopride
Rikki N Waterhouse, Raymond C Chang, Patty Carambot and Harold A Sackeim
J Cereb Blood Flow Metab 25: S614-S614; doi:10.1038/sj.jcbfm.9591524.0614
Adenovirus-induced overexpression of D2 receptors alters the responsivity of striatal dopamine
Wynne K Schiffer, David L Alexoff, Hubert H M Van Tol, Vinal Patel and Stephen L Dewey
J Cereb Blood Flow Metab 25: S615-S615; doi:10.1038/sj.jcbfm.9591524.0615
The effect of ionic environments on the affinity of D2-dopamine receptor radioligands
Christine A Parker, Julian C Matthews, John Brown, Antony D Gee and Eugenii A Rabiner
J Cereb Blood Flow Metab 25: S616-S616; doi:10.1038/sj.jcbfm.9591524.0616
Imaging retrograde transport and expression of D2 receptors after striatal gene transfer
Wynne K Schiffer, Anat R Biegon, Hubert H M Van Tol, Joanna S Fowler, Vinal Patel, Jean Logan and Stephen L Dewey
J Cereb Blood Flow Metab 25: S617-S617; doi:10.1038/sj.jcbfm.9591524.0617
New PET Tracers
Oral session
Evaluation of [11C]-(+)-PHNO as an agonist radiotracer for imaging high-affinity dopamine D2 receptors
Alan A Wilson, Nathalie Ginovart, Patrick McCormick, Doug Hussey, Ken Singh, Armando Garcia, Sylvain Houle, Philip Seean, Suzi Vanderspeck and Shitij Kapur
J Cereb Blood Flow Metab 25: S594-S594; doi:10.1038/sj.jcbfm.9591524.0594
In vivo evaluation of [11C]CNS-5161 as a use-dependent ligand for the NMDA glutamate receptor channel
Wynne K Schiffer, Deborah Pareto-Onghena, HaiTao Wu, Kuo-Shyan Lin, Andrew R Gibbs, Joanna S Fowler, Jean Logan, David L Alexoff, Stephen L Dewey and Anat R Biegon
J Cereb Blood Flow Metab 25: S595-S595; doi:10.1038/sj.jcbfm.9591524.0595
Evaluation of [C-11]R116301 as a tracer for the in vivo measurement of NK1 receptors in human subjects
Saskia P A Wolfensberger, Anu J Araiksinen, Bart N M van Berckel, Ronald Boellaard, William D H Carey, Wieb Reddingius, Dick J Veltman, Bert D Windhorst, Josée E Leysen and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S596-S596; doi:10.1038/sj.jcbfm.9591524.0596
Synthesis, in vivo evaluation and direct comparison with [18F]FPS of a novel sigma-1 receptor radiotracer [18F]2-Flouroethyl-[(4-cyanophenoxy)methyl]piperidine ([18F]WLS1.002)
Rikki N Waterhouse, Jun Zhao, Raymond C Chang and Patty Carambot
J Cereb Blood Flow Metab 25: S597-S597; doi:10.1038/sj.jcbfm.9591524.0597
Radiolabelling and in vivo evaluation of [11C]GSK215083 as potential PET radioligand for the 5-HT6 receptor in the porcine brain
Laurent Martarello, Vincent J Cunningham, Julian C Matthews, Eugenii Rabiner, Steen Jakobsen and Antony D Gee
J Cereb Blood Flow Metab 25: S598-S598; doi:10.1038/sj.jcbfm.9591524.0598
Characterization of dose dependent norepinephrine transporter blockade by atomoxetine in human brain using 11C MeNER PET
Dean F Wong, Hiroto Kuwabara, P David Mozley, Robert F Dannals, Anil Kumar, Weiguo Ye, James R Brasic, Mohab Alexander, William Mathews, Daniel Holt, Francois Vandenhende and Albert Gjedde
J Cereb Blood Flow Metab 25: S599-S599; doi:10.1038/sj.jcbfm.9591524.0599
PET Methods for Alzheimer's Disease
Oral session
Oral session
Validation of [11C]MP4A and [11C]MP4P as tracers for quantifying brain ache activity with PET based on in vivo and in vitro human studies
Noriko Tanaka, Hajime Matsuura, Hitoshi Shinotoh, Sigeki Hirano, Yasukazu Sato, Tetsuya Shiraishi, Shuichi Sendoda, Hiroki Namba, Shuichi Tanada and Toshiaki Irie
J Cereb Blood Flow Metab 25: S592-S592; doi:10.1038/sj.jcbfm.9591524.0592
Comparison of kinetic modelling strategies of N-[11C]-methylpiperidin-4-yl-proprionate ([11C]-PMP) in normals and patients with mild cognitive impairment (MCI)
Virginie Kinnard, Patrick Dupont, Mathieu Vandenbulcke, Koen Van Laere, Guy Bormans, Tjibbe de Groot, Alfons Verbruggen and Rik Vandenberghe
J Cereb Blood Flow Metab 25: S593-S593; doi:10.1038/sj.jcbfm.9591524.0593
Physiological Basis of Functional Imaging
Oral session
Plenary Symposium
Compartment-resolved imaging of activity dependent dynamics of cortical blood volume and oximetry
Amiram Grinvald, Rina Hildesheim and Ivo Vanzetta
J Cereb Blood Flow Metab 25: S681-S681; doi:10.1038/sj.jcbfm.9591524.0681
Neuronal basis of neuroimaging in motor networks
Mark Hallett
J Cereb Blood Flow Metab 25: S682-S682; doi:10.1038/sj.jcbfm.9591524.0682
Neuronal basis of optical imaging signals in sensory cortex
Anna Devor, Istvan Ulbert, Andrew K Dunn, Suresh N Narayanan, Stephanie R Jones, Mark L Andermann, David A Boas and Anders M Dale
J Cereb Blood Flow Metab 25: S683-S683; doi:10.1038/sj.jcbfm.9591524.0683
Reading vascular changes in brain imaging: Is dendritic calcium the key?
Martin J Lauritzern
J Cereb Blood Flow Metab 25: S684-S684; doi:10.1038/sj.jcbfm.9591524.0684
Plasticity and Recovery after Stroke
Oral session
Plasticity and recovery after stoke: Introduction
Barbro B Johansson
J Cereb Blood Flow Metab 25: S710-S710; doi:10.1038/sj.jcbfm.9591524.0711
Anti-Nogo-A antibody infusion improves behavioral outcome and corticospinal plasticity after experimental stroke
Anis K Mir, Christoph Wiessner, Martin Rausch, Martin E Schwab and Gwendolyn L Kartje
J Cereb Blood Flow Metab 25: S711-S711; doi:10.1038/sj.jcbfm.9591524.0712
Can exogenous stem cells improve outcome after experimental stroke? The challenge of combined MRI imaging of stem cell dynamics, cell differentiation and functional outcome
Mathias Hoehn, Ralph Weber, Pedro Ramos-Cabrer, Susanne Wegener, Dirk Wiedermann, Ekkehard Küstermann and Uwe Himmelreich
J Cereb Blood Flow Metab 25: S712-S712; doi:10.1038/sj.jcbfm.9591524.0713
Mechanisms and modulation of plasticity in motor cortex and its implication for recovery after stroke: Studies with transcranial magnetic stimulation
Cathrin M Bütefisch
J Cereb Blood Flow Metab 25: S713-S713; doi:10.1038/sj.jcbfm.9591524.0714
Functional and structural neuroimaging studies of plasticity and functional recovery
Richard S Frackowiak
J Cereb Blood Flow Metab 25: S714-S714; doi:10.1038/sj.jcbfm.9591524.0715
Pleiotropic Actions of Tissue Plasminogen Activator
Oral session
Symposium
Introduction to the neurovascular unit
Thomas P Jacobs
J Cereb Blood Flow Metab 25: S685-S685; doi:10.1038/sj.jcbfm.9591524.0685
tPA as an effector of microglial activation
Jian Wang, Iordanis Gravanis, John Sheehan and Stella Tsirka
J Cereb Blood Flow Metab 25: S686-S686; doi:10.1038/sj.jcbfm.9591524.0686
tPA as an 'interface' between blood and brain
Denis Vivien
J Cereb Blood Flow Metab 25: S687-S687; doi:10.1038/sj.jcbfm.9591524.0687
Plasminogen activators and synaptic plasticity
Nicholas W Seeds
J Cereb Blood Flow Metab 25: S688-S688; doi:10.1038/sj.jcbfm.9591524.0688
Thrombolysis - where we are
W Hacke
J Cereb Blood Flow Metab 25: S689-S689; doi:10.1038/sj.jcbfm.9591524.0689
The Ischemic Penumbra
Oral session
Plenary Symposium
Can the penumbra be detected: MR versus PET imaging
Wolf-Dieter Heiss and Jan Sobesky
J Cereb Blood Flow Metab 25: S702-S702; doi:10.1038/sj.jcbfm.9591524.0703
How long does the penumbra survive? necrotic versus apoptotic injury
Anna M Planas
J Cereb Blood Flow Metab 25: S703-S703; doi:10.1038/sj.jcbfm.9591524.0704
Does the penumbra recover: Pharmacological versus hemodynamic interventions
Eng H Lo
J Cereb Blood Flow Metab 25: S704-S704; doi:10.1038/sj.jcbfm.9591524.0705
Is there room for regeneration: Spontaneous versus induced neurogenesis
Zaal Kokaia
J Cereb Blood Flow Metab 25: S705-S705; doi:10.1038/sj.jcbfm.9591524.0706
Tracer Kinetic Modeling
Oral session
Quantification of PET studies with the high affinity D2/D3 receptor ligand [C-11]FLB-457: Re-evaluation of the validity of using a cerebellar reference region
Marie-Claude Asselin, Andrew J Montgomery, Susan P Hume and Paul M Grasby
J Cereb Blood Flow Metab 25: S605-S605; doi:10.1038/sj.jcbfm.9591524.0605
Formation of binding potential maps of adenosine A1 and A2A receptors using independent component analysis without arterial blood sampling
Mika Naganawa, Yuichi Kimura, Tadashi Nariai, Kenji Ishii, Keiichi Oda, Yoshitsugu Manabe, Kunihiro Chihara and Kiichi Ishiwata
J Cereb Blood Flow Metab 25: S606-S606; doi:10.1038/sj.jcbfm.9591524.0606
Bolus-plus-infusion transformation (BPIT) of bolus-only PET experiments: Applications to dopamine receptor and transporter ligands
Hiroto Kuwabara, Anil Kumar, Weiguo Ye and Dean F Wong
J Cereb Blood Flow Metab 25: S607-S607; doi:10.1038/sj.jcbfm.9591524.0607
Development of a tracer kinetic model for the analysis of (R)-[11C]verapamil data
Mark Lubberink, Gert Luurtsema, Bart N M van Berckel, Ronald Boellaard, Rolf Toornvliet, Eric J F Franssen and Adriaan A Lammertsma
J Cereb Blood Flow Metab 25: S608-S608; doi:10.1038/sj.jcbfm.9591524.0608
A rapid CBF/CMRO2 measurement with a single PET scan with dual-tracer/integration technique in human
Takuya Hayashi, Nobuyuki Kudomi, Hiroshi Watabe, Hisashi Oka, Kohei Hayashida, Yoshinori Miyake and Hidehiro Iida
J Cereb Blood Flow Metab 25: S609-S609; doi:10.1038/sj.jcbfm.9591524.0609
