FIGURE 3
FROM:
Adenovirus-Mediated Gene Transfer of Glial Cell Line-Derived Neurotrophic Factor Prevents Ischemic Brain Injury After Transient Middle Cerebral Artery Occlusion in Rats
Hisashi Kitagawa, Chihoko Sasaki, Kenichi Sakai, Atsushi Mori, Yasuhide Mitsumoto, Toyoki Mori, Yoshimosuke Fukuchi, Yasuhiro Setoguchi and Koji Abe
BACK TO ARTICLEFigure 3.
Effect of Ad-GDNF on infarct volume (A) and infarct area (B) at 24 hours after 90 minutes of transient MCAO. (A) Infarct volume in the brain sections of the Ad-GDNF-treated group (n = 9, **P < 0.01) was significantly smaller than that of the vehicle- (n = 9) or Ad-LacZ-treated group (n = 6). (B) Infarct area of three coronal sections (4, 6, and 8 mm caudal from frontal pole) of Ad-GDNF- (
) treated group (*P < 0.05, **P < 0.01 versus vehicle group; †P < 0.05, ††P < 0.01 versus Ad-LacZ group) was also significantly smaller than those of vehicle (
) or Ad-LacZ (
) groups. Data are expressed as mean 
SD.
