Journal of Cerebral Blood Flow & Metabolism

FIGURE 4

FROM:

Neuroprotective Effects of Human Recombinant Interleukin-1 Receptor Antagonist in Focal Cerebral Ischaemia in the Rat

Sarah A Loddick and Nancy J Rothwell

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Figure 4.

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Infarct volume measured 24 h after middle cerebral artery occlusion (MCAo) in rats injected i.c.v. with either saline or rhIL-1ra (10 microg) 30 min before and 10 min after MCAo, or O h after or 30 min after MCAo. Values are presented as a percentage of the mean lesion size of the respective vehicle-treated group, and denote the mean of eight animals; bars indicate SD. ***p < 0.001 versus saline-treated group; *p < 0.05 versus saline-treated group.

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