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References
Ogle J, Ramakrishnan V . Structural insights into translational fidelity. Annu Rev Biochem 74: 129–177 ( 2005)
Lynch S, Gonzalez R, Puglisi J . Comparison of X-ray crystal structure of the 30S subunit-antibiotic complex with NMR structure of decoding site oligonucleotide-paromomycin complex. Structure 11: 43–53 ( 2003)
Schroeder R, Waldsich C, Wank H . Modulation of RNA function by aminoglycoside antibiotics. EMBO J 19: 1–9 ( 2000)
James P, Raut S, Rivard G, Poon M-C, McKenna S, Leggo J, Lillicrap D . Aminoglycoside suppression of nonsense mutations in severe hemophilia. Blood 106: 3043–3048 ( 2005)
Magnet S, Blanchard J . Molecular insights into aminoglycoside action and resistance. Chem Rev 105: 477–497 ( 2005)
Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, Bush K, Hooper DC . Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med 12: 83–88 ( 2006)
Goh E, Yim G, Tsui W, McClure J, Surette M, Davies J . Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics. Proc Natl Acad Sci USA 99: 17025–17030 ( 2002)
Gorini L, Kataja E . Phenotypic repair by streptomycin of defective genotypes in E. coli. Proc Natl Acad Sci USA 51: 487–493 ( 1964)
Hosoya Y, Okamoto K, Murakami H, Ochi K . Acquisition of certain streptomycin-resistant (str) mutations enhances antibiotic production in bacteria. Antimicrob Agents Chemother 42: 2041–2047 ( 1998)
Shier W, Rinehart KL Jr, Gottlieb D . Preparation of four new antibiotics from a mutant of Streptomyces fradiae. Proc Natl Acad Sci USA 63: 198–204 ( 1969)
Shier WT, Rinehart KL Jr . Preparation of two new aminoglycoside antibiotics. J Antibiot 23: 51–53 ( 1970)
Davies J . Structure-activity relationships among the aminoglycoside antibiotics: comparison of the neomycins and hybrimycins. Biochim Biophys Acta 222: 674–676 ( 1970)
Benveniste R, Davies J . Structure-activity relationships among the aminoglycoside antibiotics: role of hydroxyl and amino groups. Antimicrob Agents Chemother 4: 402–409 ( 1973)
Waitz JA, Miller GH, Moss E, Moss, Chiu PJ . Chemotherapeutic evaluation of 5-episisomicin (Sch 22591), a new semisynthetic aminoglycoside. Antimicrob Agents Chemother 13: 41–48 ( 1978)
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Davies, J. Aminoglycosides: Ancient and Modern. J Antibiot 59, 529–532 (2006). https://doi.org/10.1038/ja.2006.73
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DOI: https://doi.org/10.1038/ja.2006.73
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