Original Article

The Journal of Antibiotics (2005) 58, 61–64; doi:10.1038/ja.2005.7

Favolon B, a New Triterpenoid Isolated from the Chilean Mycena sp. Strain 96180

Pedro Aqueveque1, Timm Anke2, Heidrun Anke2, Olov Sterner3, José Becerra1 and Mario Silva1

  1. 1Departamento de Botánica. Facultad de Ciencias Naturales y Oceanográficas. Universidad de Concepción, Casilla 160-C, Concepción, Chile
  2. 2Lehrbereich Biotechnologie der Universität, Paul-Ehrlich-Strase 23, D-67663 Kaiserslautern, Germany
  3. 3Division of Organic and Bioorganic Chemistry, Lund University, P.O. Box 124, S-221 00 Lund, Sweden

Correspondence: M. Silva, Departamento de Botánica. Facultad de Ciencias Naturales y Oceanográficas. Universidad de Concepción, Casilla 160-C, Concepción, Chile, E-mail: mjsilva@udec.cl

Received 11 September 2004; Accepted 10 December 2004.

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Abstract

A new biologically active triterpenoid, favolon B (1), was isolated from fermentation broths of Mycena sp. strain 96180. Favolon B showed antifungal activities towards Botrytis cinerea, Mucor miehei, Paecilomyces variotii and Penicillium notatum. No activities were observed against bacteria and yeasts. The structure of favolon B was elucidated by spectroscopic techniques.

Keywords:

terpenoids, fungi, basidiomycetes, bioactive metabolites

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References

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